There are currently 4 active clinical trials seeking participants for Anemia research studies. The states with the highest number of trials for Anemia participants are .
A Study to Determine the Efficacy and Safety of Luspatercept in Adult Participants and to Evaluate the Safety and Pharmacokinetics in and Adolescent Participants With Alpha (α)-Thalassemia
NCT05664737
Recruiting
The purpose of the study is to evaluate the efficacy and safety of luspatercept plus best supportive care (BSC) vs placebo plus BSC on anemia in adult participants with α-thalassemia hemoglobin H (HbH) disease and determine the safety and drug levels in adolescent participants.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
08/19/2025
Locations: Local Institution - 0008, Halifax, Nova Scotia +35 locations
Conditions: Anemia
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To Assess Safety of Mitapivat and Provide Proof of Concept of the Efficacy of the Drug in Patients With RBC Membranopathies or CDAII.
NCT07055243
Recruiting
This is a prospective exploratory phase 2 study designed to evaluate the safety and efficacy of mitapivat in RBC membranopathies and CDAII, a rare sub type of anemia. Nine patients from Princess Margaret who are diagnosed with CDAII will be enrolled to the study. Patients will be in the trial for 57 weeks treatment weeks and a safety follow up week after 30 days from last dose. First 8 weeks will be dose escalating period followed by 48 weeks of fixed dose period. 57th week will be dose tapering... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/03/2025
Locations: University Health Network (UHN), Toronto, Ontario
Conditions: Anemia
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Ferric Derisomaltose and Outcomes in the Recovery of Gynecologic Oncology: ERAS (Enhanced Recovery After Surgery)
NCT05407987
Recruiting
Iron deficiency has been reported in approximately 35% of patients with a gynecologic malignancy. Blood transfusions are known to be immunosuppressive and carry immediate and long-term risks. Pre-operative blood transfusion in gynecologic oncology patients is associated with higher rates of surgical site infection, length of stay, composite morbidity, cancer recurrence, and mortality. Pre-operative intravenous iron formulations have been shown in benign gynecology and other surgical specialities... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Arthur J.E. Child Comprehensive Cancer Centre, Calgary, Alberta
Conditions: Gynecologic Cancer, Anemia, Iron-deficiency
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Optimal Brain Oxygenation in Neurologic Intensive Care Unit : The NeurO2 Study
NCT04935866
Recruiting
The NeurO2 study is a multicenter observational study looking at NIRS monitoring in neurocrocritically ill patients during the acute phase of care following an acute brain injury. The study is nested within the HEMOTION Trial and the SAHaRA Trial
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/16/2022
Locations: The Ottawa Hospital, Ottawa, Ontario +1 locations
Conditions: Traumatic Brain Injury, Subarachnoid Hemorrhage, Brain Injuries, Near-Infrared Spectroscopy, Intensive Care Neurological Disorder, Anemia
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