Search
All Clinical Trials
A listing of 25513 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 25513
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Conditions:
Healthy
Healthy Volunteer Study
Featured Trial
Herpes Clinical Trial
Recruiting
Help move the future of herpes simplex virus type 2 (HSV-2) genital herpes forward by participating in the Vantage Trial for an investigational vaccine.
Conditions:
HSV-2 Infection
HSV-2
Herpes
Herpes Simplex
Genital Herpes
Genital Herpes Simplex Type 2
HSV-2 Genital Herpes
HIV-1 and HSV-2 Coinfection
Featured Trial
Fronto-Temporal Dementia Research Study
Recruiting
The aim of this study is to better understand the genetics of FTD, in order to
empower researchers with the data they need to potentially identify treatment
options. Help researchers accelerate their understanding of Frontotemporal
Dementia and get access to free, at-home genetic testing and genetic counseling
before and after your test.
empower researchers with the data they need to potentially identify treatment
options. Help researchers accelerate their understanding of Frontotemporal
Dementia and get access to free, at-home genetic testing and genetic counseling
before and after your test.
Conditions:
Frontotemporal Dementia
Alzheimer Dementia
Dementia Alzheimers
Mild Dementia
Dementia
Alzheimer Type
Alzheimer Disease
Dementia of Alzheimer Type
Parkinson's Disease
Parkinson Disease
Idiopathic Parkinson's Disease
ALS
Memory Disorders
Memory Impairment
Memory Loss
Age-Related Memory Disorders
Alzheimer's Disease
Featured Trial
Clinical Research for Alpha-1 Antitrypsin Deficiency–Associated Liver Disease
Recruiting
We’re searching for new treatments for Alpha-1 Liver Disease, but we need your help.
If you
- are between 18 to 75 years of age, inclusive
- Have a confirmed or suspected diagnosis of Alpha-1 Liver Disease
- OR have a family member with a confirmed or suspected diagnosis of Alpha-1
Liver Disease
You may be eligible to participate in a research opportunity evaluating the safety
and effectiveness of an investigational study drug.
If you
- are between 18 to 75 years of age, inclusive
- Have a confirmed or suspected diagnosis of Alpha-1 Liver Disease
- OR have a family member with a confirmed or suspected diagnosis of Alpha-1
Liver Disease
You may be eligible to participate in a research opportunity evaluating the safety
and effectiveness of an investigational study drug.
Conditions:
Crohn's Disease
COPD
Chronic Obstructive Pulmonary Disease (COPD)
Emphysema or COPD
Alpha 1-Antitrypsin Deficiency
AAT Deficiency
AATD
Chronic Obstructive Pulmonary Disease
Emphysema
Pulmonary Emphysema
Bronchiectasis
Panniculitis
Hepatocellular Carcinoma
Cirrhosis
Liver Cirrhosis
Cirrhosis
Liver
Cystic Fibrosis
Idiopathic Pulmonary Fibrosis
Pulmonary Fibrosis
Non-Alcoholic Fatty Liver Disease
Liver Diseases
Liver Disease
Vaginal Microbiome Seeding and Health Outcomes in Cesarean-delivered Neonates.
Recruiting
Neonates delivered by scheduled Cesarean Section will be randomized to receive vaginal seeding (exposing the infant to Mother's vaginal flora) or sham. Infants will be followed for three years to examine health outcomes including microbiome development, immune development, metabolic outcomes, and any adverse events.
Gender:
All
Ages:
Between 0 days and 50 years
Trial Updated:
12/06/2023
Locations: Inova Health System, Falls Church, Virginia
Conditions: Cesarean Delivery Affecting Newborn, Obesity, Childhood, Intestinal Microbiome, Microbiota, Host Microbial Interactions, Gastrointestinal Microbiome
A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative Colitis
Recruiting
The purpose of this study is to estimate and compare the incidence of overall malignancy, serious infection, and opportunistic infections between new users of ustekinumab and new users of other biologic therapies among adult participants with Crohn's disease (CD) or ulcerative colitis (UC).
Gender:
All
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: NMCP, Portsmouth, Virginia
Conditions: Crohn Disease, Colitis, Ulcerative
Feasibility and Acceptability of Using Weighted Blankets to Prevent and /or Mitigate Delirium
Recruiting
The use of weighted blankets to avert or alleviate Delirium in Adult ICU patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: VCU Health Systems, Richmond, Virginia
Conditions: Delirium
Redesigning Pediatric Primary Care Obesity Treatment: Virtual House Calls
Recruiting
This study examines a redesign of pediatric primary care overweight/obesity treatment, augmenting typical in-person visits with: (1) direct-to-patient video telehealth to tailor counseling advice to families, (2) that leverages certified health coaches as a part of the care team, and (3) creates skills building in real-time within the home environment.
Gender:
All
Ages:
9 years and above
Trial Updated:
12/04/2023
Locations: Virginia Commonwealth Universiy, Richmond, Virginia
Conditions: Obesity, Pediatric
The Abuse Liability of a Novel Heated Tobacco Product (IQOS) and Its Feasibility as a Menthol Cigarette Substitute
Recruiting
This project examines the influence of flavor availability on switching to an MRTP known as IQOS, part of the Heated Tobacco Product (HTP) class, among menthol smokers using clinical lab and naturalistic evaluations of abuse liability. Results will help federal regulators predict the public health impact on menthol cigarette smokers of policies restricting access to menthol-flavored HTPs.
Gender:
All
Ages:
21 years and above
Trial Updated:
12/02/2023
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Tobacco Use
Water Intake and Weight Control in Older Adults
Recruiting
This study is a randomized controlled intervention trial in adults aged 50+ years with overweight or obesity, which will compare three groups with different diet prescriptions: 1) pre-meal water consumption (500 ml, before each main meal) with a hypocaloric diet; 2) 1500 ml water consumed throughout the day with a hypocaloric diet; 3) hypocaloric diet with no instructions regarding water consumption. Smart water bottles will objectively assess water intake timing and volume. Urine osmolality, ur... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
12/01/2023
Locations: Virginia Tech, Blacksburg, Virginia
Conditions: Overweight and Obesity
Automated Insulin Delivery (AID) for Basal Insulin Titration in Type 2 Diabetes
Recruiting
The purpose of this clinical trial is to test the safety and feasibility of using an Automated Insulin Device (AID) in people with Type 2 Diabetes under basal insulin injections to achieve safe and fast basal insulin titration. Participants will be randomized to either the control group or the experimental group. If in the experimental group, the participant will use an insulin pump with Control-IQ Technology (Tandem Diabetes Care) for ten days. Researchers will compare the glycemic control of t... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/29/2023
Locations: University of Virginia Center for Diabetes Technology, Charlottesville, Virginia
Conditions: Type 2 Diabetes
Optimizing Pain Self-Management in Total Knee Arthroplasty
Recruiting
The purpose of this study is to investigate the efficacy of a positive affect enhancing intervention designed to reduce pain and augment reward system function in knee osteoarthritis (KOA) patients undergoing total knee arthroplasty (TKA). The scientific premise is that patient use of a positive emotion generative practice - savoring meditation, which has been demonstrated to reduce pain in experimental laboratory settings, enhanced with a pain neuroscience education component about reward syste... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
11/29/2023
Locations: Fontaine Research Park, Charlottesville, Virginia
Conditions: Osteo Arthritis Knee, Knee Pain Chronic, Surgery
The Effects of Oral Inorganic Nitrate Supplementation on Lower Limb Perfusion During Exercise in Patients With PAD
Recruiting
Peripheral arterial disease (PAD) is a highly prevalent and costly condition. Intermittent claudication (IC), defined as ischemic leg pain that occurs with walking, results in functional impairment, reduced daily physical activity, and a lower quality of life. Although the mechanisms contributing to functional impairment are not fully delineated, current evidence suggests that the uncoupling of skeletal muscle cellular metabolism from tissue perfusion may be responsible for exercise intolerance.... Read More
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
11/28/2023
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Peripheral Arterial Disease, Peripheral Vascular Diseases
Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status
Recruiting
The purpose of the study is to determine associations between fitness status, bacteria in the mouth, and the blood flow to muscle. This study is trying to find out if fitness status impacts the bacteria that are present in the oral microbiome (environment in the mouth) or the ability of the body to send blood to the skeletal muscle.
Participants will complete all or some of the following:
A mouth swab to assess the bacteria in their mouths.
Produce a saliva sample into a tube.
Cycle on a bike... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: UVA Student Health and Wellness Building, Charlottesville, Virginia
Conditions: Heart Failure, Systolic, Heart Failure, Diastolic, Peripheral Arterial Disease, Overweight and Obesity
The Group Risk Reduction Intervention Therapy (GRRIT) Project
Recruiting
Investigators will evaluate a group format adaptation of Brief Cognitive-Behavioral Therapy for Suicide (i.e., G-BCBT) on suicide ideation (Aim 1), ability to use coping strategies (Aim 2), and overall mental health (exploratory analysis). The combination of tailored means safety counseling and training in evidence-based emotion regulation and cognitive flexibility skills delivered via a 12-session group therapy treatment will decrease service members' overall suicide risk. The group format will... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
11/28/2023
Locations: Naval Medical Center Portsmouth, Portsmouth, Virginia
The Use of Memantine for Prevention of Alzheimer's Disease
Recruiting
As the US population ages, the prevalence of dementia is increasing, and Alzheimer's Disease (AD) is the most prevalent one. Solving the Alzheimer's Disease (AD) epidemic is likely to require preventive therapy beginning many years before symptoms are expected to be evident in at-risk individuals. AD is caused by the dysfunction, loss of synapses, and eventual neuronal death, which may occur up to 25 years before clinical symptoms appear. This study, based off of pre-clinical data, seeks to asse... Read More
Gender:
All
Ages:
Between 50 years and 65 years
Trial Updated:
11/28/2023
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Alzheimer Disease
1 - 12 of 25513