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All Clinical Trials
A listing of 24325 clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 24325
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Studying an Investigational Vaccine for a Common Herpesvirus in Adolescents
Recruiting
This study aims to evaluate the safety, effectiveness, and immune response of an investigational vaccine targeting cytomegalovirus (CMV), a common type of herpesvirus. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. The study will monitor participants’ health and immune response over an 18-month period. Should you express interest for the adolescent in your care, you will be contacted directly by the research site. They will provide further details and address any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Preventative Trials
Healthy
All Conditions
Parent / Carer of child aged 0-17
Featured Trial
Investigational Combined COVID-19 and Influenza Vaccine
Recruiting
This study aims to evaluate the safety, immune response, and tolerability of an investigational vaccine designed to protect against both COVID-19 and seasonal influenza in adults aged 18 to 64 years. Participants will be randomly assigned to receive the investigational vaccine or a currently available vaccine. The study involves a single vaccination followed by monitoring over several months. Should you express interest, the research site will contact you directly to provide further details and address any questions you may have about study requirements, risks/benefits, and compensation.
Conditions:
Interested in vaccine studies
All Conditions
Healthy
Preventative Trials
Featured Trial
Investigational Stomach Flu Vaccine
Recruiting
The main objectives of this study are to assess the safety and effectiveness of an investigational vaccine aimed at preventing norovirus, commonly known as the stomach flu. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Interested in vaccine studies
All Conditions
Preventative Trials
Healthy
Age 60+
Featured Trial
Healthy Volunteer Oral COVID-19 Preventative Drug
Recruiting
The main objectives of this study are to assess the safety, effectiveness, and immune response of an investigational oral preventative drug (oral vaccination) in preventing COVID-19 and its symptoms. Participants will be randomly assigned to receive the investigational oral vaccine or a currently available market COVID-19 vaccine. Should you express interest, you will be contacted directly by the research site, who will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Preventative Trials
Healthy
All Conditions
Interested in vaccine studies
Featured Trial
Studying an Investigational Vaccine for a Common Herpesvirus
Recruiting
This study aims to evaluate the safety, effectiveness, and immune response of an investigational vaccine targeting cytomegalovirus (CMV), a common type of herpesvirus. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. The study will monitor participants’ health and immune response over an 18-month period. Should you express interest, the research site will contact you directly to provide further details and address any questions you may have about study requirements, risks/benefits, and compensation.
Conditions:
All Conditions
Adolescent Trials
Preventative Trials
Pediatric
Healthy
A Study of the C-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced And/or Metastatic Solid Tumors Known to Express C-Kit
Recruiting
This open-label clinical trial will evaluate the safety and tolerability of NN3201 in subjects with advanced and/or metastatic solid tumors known to express c-Kit.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/11/2025
Locations: NEXT Virginia, Fairfax, Virginia
Conditions: Gastrointestinal Stromal Tumors, Small-cell Lung Cancer, Adenoid Cystic Carcinoma, Uveal Melanoma, Neuroendocrine Tumors, Chromophobe Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma
Reduced CT + Anti-PD-1 as First Line Tx in Vulnerable Older Adults w/Adv <50% PD-L1 Non-Small Cell Lung Cancer (NSCLC)
Recruiting
Evaluate frequency of adverse events that lead to chemotherapy discontinuation in vulnerable older adults with recurrent/metastatic PD-L1 TPS\<50% NSCLC patients who receive reduced dose chemotherapy in combination with immunotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/11/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Non-Small Cell Lung Cancer, NSCLC, Advanced Non-Small Cell Lung Cancer, Metastatic Non Small Cell Lung Cancer
CALM: Managing Distress in Malignant Brain Cancer
Recruiting
The purpose of this study is to test an empirically supported psychotherapeutic intervention, Managing Cancer and Living Meaningfully (CALM), compared to treatment as usual (TAU) in those with malignant brain cancer diagnoses.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/10/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Brain Tumor, Brain Metastases, Brain Cancer, Metastatic Lung Cancer, Metastatic Breast Cancer, Metastatic Melanoma, Metastatic Colon Cancer, Metastatic Kidney Cancer
Oral Health In Cirrhosis of the Liver (ORACLE)
Recruiting
The goal of this observational study is to learn about dental evaluation and periodontal cleaning along with scheduled follow -up on the dental health and overall health of patients with cirrhosis and also to determine what barrier(s) if any exist to improve oral health in this population.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/10/2025
Locations: Hunter Holmes McGuire VA Medical Center, Richmond, Virginia +1 locations
Conditions: Cirrhosis, Periodontal Diseases
Temporal Window and Episodic Future Thinking in CUD
Recruiting
The primary objective is to test the theory of Reinforcer Pathology via manipulation of the temporal window with successive Episodic Future Thinking generation in individuals with cocaine use disorder.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/10/2025
Locations: Fralin Biomedical Research Institute at VTC, Roanoke, Virginia
Conditions: Cocaine Use Disorder
Hepatic Encephalopathy and Albumin Lasting Cognitive Improvement
Recruiting
Hypothesis: Improvement in cognitive dysfunction with IV albumin in patients with cirrhosis with prior HE and MHE lasts for several weeks after albumin infusion has ended, and is due to persistent improvement in inflammatory markers, endothelial dysfunction, albumin function and gut microbial changes.
This will be a single-arm, single-blind sequential trial of IV 25% albumin and IV saline over 8 weeks with biological sampling and cognitive and health related quality of life (HRQOL) testing with... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/10/2025
Locations: Hunter Holmes McGuire VA Medical Center, Richmond, Virginia
Conditions: Cirrhosis, Hepatic Encephalopathy
Behavioral Exercise TRaining for Men Undergoing Androgen Depr Therapy for Prostate Ca
Recruiting
To refine a remote behavioral exercise training intervention for testing in a larger randomized trial.
Gender:
MALE
Ages:
Between 41 years and 85 years
Trial Updated:
02/10/2025
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Prostate Cancer
Decision Making in Chronic Pain and Alcohol Use Disorder
Recruiting
The objective of this within-subject study is to test the effects of Episodic Future Thinking (EFT) and Low-intensity Focused Ultrasound (LIFU) interventions on the pain of subjects who have chronic pain and alcohol use disorder(s).
Gender:
ALL
Ages:
21 years and above
Trial Updated:
02/10/2025
Locations: Fralin Biomedical Research Institute at VTC, Roanoke, Virginia
Conditions: Alcohol Use Disorder, Chronic Pain
Physical Exam, Static & Dynamic Ultrasound Assessment, & Treatment of Thoracolumbar Fascia (TLF) Mediated Low Back Pain
Recruiting
This Study is for our continued study of the Thoracolumbar Fascia (TFL) in patients with and without low back pain by our experienced multidisciplinary team:
Vincent Wang PhD, VT Biomedical Engineering \& Mechanics (BEAM). Albert J Kozar DO, FAOASM, R-MSK. P. Gunnar Brolinson, DO, FAOASM, FAOCFP. David T. Redden PhD, VCOM Research Biostatistician. Matthew Chung DO, VCOM and Team Physician at Virginia Tech. Edward Magalhaes, PhD, LPC, Psychiatry and Neuro- Behavioral Sciences, VCOM.
This listin... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
02/07/2025
Locations: Edward Via College of Osteopathic Medicine, Blacksburg, Virginia
Conditions: Low Back Pain, Chronic Low-back Pain, Acute Low Back Pain
Pain Control and Quality of Recovery After Intravenous Methadone Versus Intrathecal Morphine in Major Abdominal Surgery
Recruiting
Moderate to severe postoperative pain is relatively common after major abdominal surgery. It is associated with less than optimal surgical experience, poor quality of recovery, and the development of persistent postsurgical pain. Opioids remain a significant component of postoperative pain management. Side effects of opioids used for the treatment of postoperative pain include constipation, pruritus, nausea, and vomiting. Enhanced recovery after surgery (ERAS) protocols involve the utilization o... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/06/2025
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Pain, Postoperative
InsuLearn Feasibility with Type 1 Diabetes Patients Under MDI Therapy
Recruiting
This is a 24-hour, randomized, crossover, single-center trial where participants are randomized to either start with the InsuLearn intervention or the usual care (UC) intervention. In the InsuLearn intervention, insulin doses are optimized using data collected in a 4-weeks at home data collection period.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/06/2025
Locations: University of Virginia Center for Diabetes Technology, Charlottesville, Virginia
Conditions: Type 1 Diabetes Mellitus
Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer
Recruiting
This is phase 2 trial of neoadjuvant therapy and short-course radiotherapy in resectable rectal cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2025
Locations: Virginia Cancer Institute, Richmond, Virginia +2 locations
Conditions: Rectal Cancer
1 - 12 of 24325