Survivorship and Patient Outcomes of Primary Total Hip Arthroplasty With the Ovation Hip System
Recruiting
The objective of this study is to evaluate patient outcomes in regards to safety and effectiveness based on the clinical performance of the reference devices to further support the assessment of residual risk identified in the Clinical Evaluation Report for the Ortho Development Hip System.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/13/2019
Locations: Straub Medical Center, Honolulu, Hawaii
Conditions: Joint Diseases, Osteoarthritis, Hip, Rheumatoid Arthritis, Psoriatic Arthritis, Avascular Necrosis of Hip
Antibiotic Irrigations for Intra-Abdominal Drains
Recruiting
Intra-abdominal abscesses are pus-filled pouches in the abdominal cavity. Current standard of care includes drain placement in the abscess cavity to reach source control as well as administration of systemic antibiotics. It is common practice to flush the drain on a daily basis to ensure patency. This study aims to analyze the clinical impact of a higher local concentration of antibiotics (rather than normal saline) provided through drain irrigation with an antimicrobial agent (Gentamicin and/or... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/05/2019
Locations: The University of Iowa, Iowa City, Iowa
Conditions: Abdominal Abscess
Investigate the Development and Progression of Lung Disease in Rheumatoid Arthritis Over Time
Recruiting
The purpose of this study is to investigate the link between the lungs and rheumatoid arthritis (RA). Additionally, to understand why RA patients get lung disease, how to treat, and prevent the disease.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/05/2019
Locations: National Jewish Health, Denver, Colorado
Conditions: Rheumatoid Arthritis, Lung Diseases
Metabolomics and Genetic Diagnosing Pancreatic Neuroendocrine Tumors in MEN1 Patients
Recruiting
Objectives: The aim of the present study is to assess the significance of metabolomics and genetics in diagnosing and survival evaluation for pNET in the periodic follow-up of MEN1 patients. Aim 1: To evaluate the relationship of serum global metabolic profiles with subsequent development of aggressive PNET and evaluate patients survival in a nested case-control study of MEN1 patients who have developed aggressive PNETs (cases) and MEN1 patients who have developed non-aggressive PNETs (control... Read More
Gender:
All
Ages:
All
Trial Updated:
05/21/2019
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Multiple Endocrine Neoplasia
Prospective Study of Colon Serrated Polyps
Recruiting
With this study, the investigators plan to review the clinical, epidemiology, pathology, and endoscopic features of colon serrated lesions as well as outcome of endoscopic resection of these lesions. The findings will help us define the natural history of colon serrated lesions, develop techniques for endoscopic management of patients with serrated lesions, and identity areas for improvement. The data will be used for continuing quality improvement and presenting our outcomes at academic meeting... Read More
Gender:
All
Ages:
All
Trial Updated:
05/13/2019
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Colon Polyps
The Collection and Storage of Umbilical Cord Blood for Transplantation
Recruiting
The goal of this study is to collect blood samples from the umbilical cords of newborn babies, as soon as they are delivered, and to place these samples in the MD Anderson Cord Blood Bank. Your sample may be included in the National Cord Blood Inventory (NCBI) which is part of the CW Bill Young Cell Transplantation Program. The NCBI is a federally-supported program to assist in the collection of cord blood. Cord blood will be made available to patients through The National Marrow Donor Program (... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/10/2019
Locations: MD Anderson Cord Blood Bank Collection Sites, Houston, Texas
Conditions: Cord Blood Stem Cell Transplantation, Cord Blood Transplantation, Hematopoietic Stem Cell Transplantation
Prospective Study of Colonoscopic Resection of Large Polyps and Flat Lesions
Recruiting
With this study, the investigators plan to review the performance of colonoscopic resection of large (> 1 cm) and flat lesions in the colon. The findings will help us define the role of colonoscopic resection of colon polyps and flat lesions and identity areas for improvement. The data will be used for continuing quality improvement and presenting our outcomes at academic meetings and publishing our results in peer reviewed journals.
Gender:
All
Ages:
All
Trial Updated:
05/10/2019
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Colon Polyps
Use of Sugammadex for Reversal of Paralysis in Microlaryngoscopy
Recruiting
Use of Muscle relaxant and reversal with Sugammadex at end of airway procedures will reduce the time to extubation after end of procedure
Gender:
All
Ages:
18 years and above
Trial Updated:
04/26/2019
Locations: WVU Healthcare Ruby Memorial Hospital, Morgantown, West Virginia
Conditions: Microlaryngoscopy, Rigid Bronchoscopy
A Comparison of NETSPOT Imaging Versus F-FDG-PET in Head and Neck Cancer Patients
Recruiting
This is a proof-of-concept trial to compare 18F-FDG-PET/CT with NETSPOT (68Ga-DOTA-TATE), a commercially available radiotracer packet that utilizes 68Ga to image SSTR-specific tissue.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2019
Locations: West Virginia University Medicine, Morgantown, West Virginia
Conditions: Head and Neck Squamous Cell Carcinoma
MyHeart Counts Cardiovascular Health Study
Recruiting
The MyHeart Counts Cardiovascular Health Study will utilize mobile health capabilities of smartphones and wearables to assess daily activity measures of the general population and compare these to measures of cardiovascular health risk factors and fitness. How people divide their time among exercise, sedentary behavior, and sleep all affect cardiovascular health, yet to date these have largely gone unmeasured. With the advancement of phone sensors and wearable fitness tracking devices these fact... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/09/2019
Locations: Stanford University, Stanford, California
Conditions: Cardiovascular Health
Hypofractionated Image Guided Proton Therapy for Low andIntermediate Risk Prostate Cancer
Recruiting
This study is being proposed to evaluate the use of moderate hypofractionated proton therapy in low and intermediate risk prostate cancer patients. Quality of life outcomes as well as gastrointestinal and genitourinary early and late toxicities will be analyzed and compared to conventional proton therapy regimens. It is thought that this regimen will produce comparable findings and would result in substantial health care cost savings, as well as, be more convenient for patients.
Gender:
Male
Ages:
18 years and above
Trial Updated:
04/03/2019
Locations: Provision Cares Proton Therapy Center Knoxville, Knoxville, Tennessee +1 locations
Conditions: Prostate Cancer
Smoking Cessation With Varenicline in Schizophrenia: Antipsychotic-Induced Neurological Symptoms as Correlates
Recruiting
To test the feasibility of studying effects of smoking cessation with varenicline on antipsychotic drug-induced neurological side effects, we propose a 12 week pilot study of smoking cessation treatment with varenicline in 10 schizophrenia or schizoaffective disorder patients who are actively smoking and have pre-existing TD while receiving stable doses of antipsychotics. Subjects will be followed after a 2 week baseline period to assess changes in smoking status and neurological symptoms using... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/20/2019
Locations: Corporal Michael J Crescenz VA Medical Center, Philadelphia, Pennsylvania
Conditions: Schizophrenia, Schizoaffective Disorder, Tobacco Smoking, Tardive Dyskinesia, Parkinsonism