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All Clinical Trials
A listing of clinical trials actively recruiting patient volunteers.
61 - 72 of 25482
Featured Trial
CMV Vaccine Trial For Young Women Ages 16-17
Recruiting
A Cytomegalovirus (CMV) Investigational Vaccine Clinical Trial for Healthy Women Age 16 to 17 years old. Compensation included.
Conditions:
Healthy Volunteers
Healthy
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Conditions:
Healthy
Healthy Volunteer Study
Featured Trial
Resistant Hypertension Clinical Trial
Recruiting
This clinical trial is seeking volunteers that take three or more medications daily and still routinely have a systolic (top number) blood pressure above 145.
Conditions:
High Blood Pressure
Hypertension
Resistant Hypertension
Featured Trial
Paid Vaccine Study For Teens
Recruiting
Vaccine study that aims to protect teens ages 12–17 against Epstein-Barr virus (EBV) and infectious mononucleosis (mono).
Conditions:
Healthy
Healthy Volunteer Study
The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA
Recruiting
The term "Overlap Syndrome" (OS) is used to describe the presence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in a single patient. Due to premature aging, patients with OS are prone to developing functional decline up to 20 years earlier than the general population. The International Classification of Functioning, Disability and Health (ICF) evaluates functional status in chronic pulmonary disease globally in 5 domains. The investigators propose to stud... Read More
Gender:
All
Ages:
All
Locations: Salem VA Medical Center, Salem, VA, Salem, Virginia
Conditions: COPD, OSA
Platelet Adhesion in the Pathobiology of Aortic Stenosis
Recruiting
Aortic stenosis (AS) is a serious and common condition that affects 2-3% of the population >65 years of age in Western countries. It is also responsible for extraordinarily high healthcare expenditures, estimated to be over $6 billion annually,2 in part because the primary treatment for severe AS is aortic valve replacement (AVR) which is resource-intensive. Valve abnormalities are frequently recognized before AS becomes severe, or before there is need for guideline-directed procedural intervent... Read More
Gender:
All
Ages:
25 years and above
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Aortic Valve Stenosis
Determination of Core Body Temperature in Parturient Warmed With Upper or Underbody Forced Air Cover (Bair Hugger)
Recruiting
This study is intended to calculate the core body temperature in patients who are having a Cesarean Section (C/S) and are kept warm with an Upper Body Forced Air Warming device (Bair Hugger) or underbody forced air warmer. These warming devices are approved and are a required item in many if not all surgical procedures. They are used daily throughout the hospital. The research question is: Where is the best place to position the warming blanket in pregnant mothers undergoing Cesarean section del... Read More
Gender:
Female
Ages:
18 years and above
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Cesarean Section
Study of Hepatitis Eradication Receiving Protease Inhibitor Administration
Recruiting
This is a prospective, non-blinded cohort study that will assess the safety, tolerability, and antiviral efficacy of glecaprevir/pibrentasivir therapy given post-discharge to HCV-negative recipients of HCV infected donors. Patients who meet entry criteria will be enrolled while on the transplant waitlist. At the time of transplant, some donors will be HCV positive / NAT positive and some will not be infected. Enrolled patients who receive an HCV negative donor will serve as contemporaneous contr... Read More
Gender:
All
Ages:
18 years and above
Locations: Sentara Norfolk General Hospital, Norfolk, Virginia
Conditions: Coronary Artery Disease, Morality
Exercise Dose and Metformin for Vascular Health in Adults With Metabolic Syndrome
Recruiting
Health organizations recommend exercise in an intensity based manner to promote cardiovascular adaptation and prevent disease. Metformin is a common anti-diabetes medication that reduces future type 2 diabetes and cardiovascular disease (CVD) risk. However, the optimal dose of exercise to be combined with metformin for vascular health remains unknown. The purpose of this study is to evaluate whether combining high or low intensity exercise with metformin has the potential to outperform either ex... Read More
Gender:
All
Ages:
Between 40 years and 70 years
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Metabolic Syndrome
Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury
Recruiting
The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with chronic spinal cord injury.
Gender:
All
Ages:
Between 18 years and 65 years
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Spinal Cord Injuries, Neuropathic Pain
Focused Ultrasound and Gemcitabine in Breast Cancer
Recruiting
This study will test the use of focused ultrasound ablation, low-dose gemcitabine (a chemotherapy) and the combination of focused ultrasound ablation plus low-dose gemcitabine in patients with early-stage breast cancers. We will be testing the effects of each of these regimens on cells in the immune system. We hypothesize that the combination of focused ultrasound ablation and gemcitabine will decrease myeloid-derived suppressor cells and will increase T cell activity. We also hypothesize that f... Read More
Gender:
All
Ages:
18 years and above
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Breast Cancer, Breast Neoplasms
Study of Nicotine for Pain Associated With Chemotherapy-Induced Peripheral Neuropathy
Recruiting
Assess the efficacy of short-term nicotine transdermal patch administration for the treatment of CIPN in cancer stable patients or patients in remission.
Gender:
All
Ages:
18 years and above
Locations: Virginia Commonwealth University, Richmond, Virginia +1 locations
Conditions: Neuropathy, Peripheral Neuropathy, Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy
The Role of Altered Nutrient Partitioning in Food Reward
Recruiting
Obesity remains a public health epidemic despite substantial advances in treatment strategies and therapies in the last decade. Effective strategies to support maintenance of improved metabolic health and reduced body weight are still needed.
Signals from the gut to the brain are important in regulating metabolism and energy balance and have been linked with food reward and preference in metabolically healthy individuals with normal body mass index. In particular, post-ingestive signaling relat... Read More
Gender:
All
Ages:
Between 18 years and 45 years
Locations: Fralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, Virginia
Conditions: Overweight and Obesity
Ultra-processed Food Consumption, Gut Microbiota, and Glucose Homeostasis
Recruiting
Advancing age is associated with gut dysbiosis, low-grade chronic inflammation, progressive insulin resistance, and increased risk of type 2 diabetes (T2D). Prediabetes is present in 45-50% of middle-aged/older adults, and declines in glucose tolerance are evident in the third or fourth decade of life. Thus, there is an urgent need to identify new approaches for the prevention of type 2 diabetes among middle-aged adults. Observational research has linked intake of ultra-processed foods (UPF), wh... Read More
Gender:
All
Ages:
Between 45 years and 65 years
Locations: Virginia Tech, Blacksburg, Virginia
Conditions: Insulin Sensitivity, 24-hour Glucose Control
Effectiveness of Immersive Virtual Reality Combined With Task-Specific Training on Hemiplegic Arm Function Following Stroke: A Single Case Series Study.
Recruiting
The purpose of this research study is to understand the efficacy of using an immersive Virtual Reality (VR) environment, with task-specific training, to encourage arm movement following stroke.
Gender:
All
Ages:
18 years and above
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Stroke
The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort
Recruiting
The purpose of this study is to compare patient responses during and after surgery when local anesthetic is used for dental treatment under general anesthesia (GA) and when it is not used.
Gender:
All
Ages:
6 years and below
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Pain, Procedural
61 - 72 of 25482