T

he esophagus is a tube that connects the throat to the stomach, running down the middle of your chest behind your heart, and carrying foods and liquids from your mouth to the digestive system. Most adult’s esophagi are about 25 centimeters long and are lined by mucosa (a moist membrane that protects tissues) and muscle fibers.

The main function of the esophagus is to guide foods and fluids to the stomach avoiding foreign material (food, liquids, stomach acid or foreign objects) to enter into your trachea and lungs. There are two sphincter muscles – upper and lower – in the esophagus that are tightly closed in order to prevent stomach juices from traveling up the esophagus and also to prevent unwanted secretions from traveling to stomach. These muscles open up when you are eating, drinking, breathing, belching, etc.

A weakened lower esophageal sphincter is usually responsible for chronic acid reflux, also known as gastroesophageal reflux disease (GERD).

Match to Esophageal Cancer Clinical Trials

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What is Esophageal Cancer?

Esophageal cancer is a type of cancer that occurs healthy cells start to grow and divide uncontrollably creating growths (known as tumors) along the surface of the esophagus. Doctors diagnose esophageal cancer using a camera-guided scope (endoscopy) to explore the esophagus and look for any abnormalities such as nodules or areas of irritation. If the doctor found any signs of cancer during an endoscopy they may order a biopsy to collect a sample of the abnormal growth. These tissues are analyzed for any potential cancer cells.

There are two main types of esophageal cancer: squamous cell carcinoma and adenocarcinoma.

Squamous cell carcinomas develop from normal squamous cells that run along the surface of the esophagus. On the other hand, adenocarcinomas are formed from gland cells present in the lower third of the esophagus, and it is believed to be caused mainly by the continuous exposure to stomach acid.

What Are the Symptoms of Esophageal Cancer?

Early stage esophageal cancer usually doesn’t have any symptoms, however, as the cancer progresses it starts to cause the following problems and discomforts:

  • Trouble swallowing
  • Chest or back pain
  • Chronic heartburn or indigestion
  • A cough and/or hoarseness
  • Shortness of breath and/or fatigue
  • Unexplained weight loss and loss of appetite

What Causes Esophageal Cancer?

The causes of esophageal cancer are still not fully understood. However, doctors believe that there are a few risk factors that appear to increase a person’s risk for developing this kind of cancer.

Tobacco and Alcohol Use

Tobacco and drinking alcohol seems to damage DNA cells in the lining of the esophagus, which may lead them to mutate and become cancerous.

Gender

Men are three to four times more likely than women to develop esophageal cancer.

Being Overweight or Obese

Obesity and having too much body fat seems to increase the likelihood of developing esophageal cancer. However, researchers are still trying to find out why that happens.

Barrett’s Esophagus

Barrett’s esophagus is a condition that develops from chronic GERD in which the normal lining of the esophagus changes as a result of the constant acid exposure. Though Barrett’s Esophagus is not a form of cancer, some individuals with this condition develop esophageal cancer later on.

Diet

A diet low fruits and vegetables and some vitamin deficiencies have been observed to increase an individual’s risk of developing this type of cancer.

Esophageal Cancer Clinical Trials

Unfortunately, because esophageal cancer is rarely diagnosed early it has one the lowest survival rates. For that reason, doctors and researchers are constantly looking for better screening and diagnostic methods as well as more effective treatments. In order to test new approaches, researchers design clinical trials that involve esophageal cancer patients.

The main goal of a clinical trial is to assess if a new drug or intervention is safe, effective, and altogether a better alternative than available options. Clinical trials are very carefully evaluated by internal and external agencies to ensure that the health and safety of volunteers are never compromised.

ClinicalTrials.gov: Recruiting Studies | esophageal cancer | Last update posted in the last 300 days Studies found on ClinicalTrials.gov by a search of: Recruiting Studies | esophageal cancer | Last update posted in the last 300 days

  • A MULTICENTER CANCER BIOSPECIMEN COLLECTION STUDY
    on August 12, 2020 at 4:00 pm

    Conditions:   Cancer of Head and Neck;   Lung Cancer, Nonsmall Cell;   Small-cell Lung Cancer;   Urothelial Carcinoma;   Gastroesophageal Junction Adenocarcinoma;   Cervical Cancer;   Esophageal Squamous Cell Carcinoma;   Triple Negative Breast Cancer;   Hepatocellular Carcinoma;   Renal Cell Carcinoma;   Colorectal CancerIntervention:   Diagnostic Test: OncoPrism™ assaySponsors:   Cofactor Genomics, Inc.;   Curebase, Inc.Recruiting

  • Study of Pembrolizumab Plus Trastuzumab or Trastuzumab Alone After Surgery in Patients With Esophagogastric Tumors
    on August 12, 2020 at 4:00 pm

    Conditions:   Esophagogastric Tumors;   Gastric Cancer;   Gastric Tumor;   Esophageal Cancer;   Esophageal Neoplasms;   Esophageal Tumor;   GastroEsophageal Cancer;   Gastroesophageal Junction Adenocarcinoma;   Gastroesophageal Junction Tumor;   Gastroesophageal Junction CancerInterventions:   Drug: Trastuzumab;   Drug: PembrolizumabSponsor:   Memorial Sloan Kettering Cancer CenterRecruiting

  • Combination of Metronomic Capecitabine With Camrelizumab for Treatment of Refractory Solid Tumor Trial (Cohort 2)
    on August 12, 2020 at 4:00 pm

    Condition:   Head and Neck Cancer / Esophageal Squamous CancerIntervention:   Drug: Capecitabine, CamrelizumabSponsor:   Ruijin HospitalRecruiting

  • Measurement of Diaphragmatic Dysfunction After Thoracic Surgery
    on August 11, 2020 at 4:00 pm

    Conditions:   Diaphragm Injury;   Phrenic Nerve Paralysis;   Thoracic Cancer;   Postoperative ComplicationsIntervention:   Procedure: Lung lobectomy OR esophagus cancer resectionSponsor:   Aarhus University HospitalRecruiting

  • Study of BO-112 With Pembrolizumab for Colorectal or Gastric/GEJ Cancer With Liver Metastasis
    on August 11, 2020 at 4:00 pm

    Conditions:   Colorectal Cancer;   Gastric Cancer;   Oesophageal CancerInterventions:   Procedure: Hepatic Biopsy;   Drug: BO-112 with PembrolizumabSponsor:   Bioncotech TherapeuticsRecruiting

  • Camrelizumab in Combination With Neoadjuvant Chemotherapy for Resectable Thoracic Esophageal Squamous Cell Carcinoma
    on August 10, 2020 at 4:00 pm

    Condition:   Esophageal Squamous Cell CarcinomaInterventions:   Drug: Camrelizumab;   Drug: Paclitaxel for Injection (Albumin Bound);   Drug: CarboplatinSponsor:   Zhejiang Cancer HospitalRecruiting

  • 99m Tc-3PRGD2 SPECT/CT Imaging in the Diagnosis of Lymph Node Metastasis of Esophageal Carcinoma
    on August 7, 2020 at 4:00 pm

    Conditions:   Esophageal Cancer;   Lymph Node Metastases;   Diagnoses DiseaseIntervention:   Diagnostic Test: 99mTc-3PRGD2Sponsors:   Fifth Affiliated Hospital, Sun Yat-Sen University;   Peking UniversityRecruiting

  • Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes
    on August 6, 2020 at 4:00 pm

    Conditions:   Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8;   Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage 0 Gastric Cancer AJCC v8;   Clinical Stage I Esophageal Adenocarcinoma AJCC v8;   Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage I Gastric Cancer AJCC v8;   Clinical Stage II Esophageal Adenocarcinoma AJCC v8;   Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage II Gastric Cancer AJCC v8;   Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8;   Clinical Stage IIA Gastric Cancer AJCC v8;   Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8;   Clinical Stage IIB Gastric Cancer AJCC v8;   Clinical Stage III Esophageal Adenocarcinoma AJCC v8;   Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage III Gastric Cancer AJCC v8;   Clinical Stage IV Esophageal Adenocarcinoma AJCC v8;   Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage IV Gastric Cancer AJCC v8;   Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8;   Clinical Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage IVA Gastric Cancer AJCC v8;   Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8;   Clinical Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage IVB Gastric Cancer AJCC v8;   Hepatobiliary Neoplasm;   Malignant Digestive System Neoplasm;   Malignant Female Reproductive System Neoplasm;   Malignant Genitourinary System Neoplasm;   Malignant Neoplasm;   Pathologic Stage 0 Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage 0 Gastric Cancer AJCC v8;   Pathologic Stage I Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage I Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage I Gastric Cancer AJCC v8;   Pathologic Stage IA Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IA Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IA Gastric Cancer AJCC v8;   Pathologic Stage IB Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IB Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IB Gastric Cancer AJCC v8;   Pathologic Stage IC Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage II Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage II Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage II Gastric Cancer AJCC v8;   Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IIA Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IIA Gastric Cancer AJCC v8;   Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IIB Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IIB Gastric Cancer AJCC v8;   Pathologic Stage III Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage III Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage III Gastric Cancer AJCC v8;   Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IIIA Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IIIA Gastric Cancer AJCC v8;   Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IIIB Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IIIB Gastric Cancer AJCC v8;   Pathologic Stage IIIC Gastric Cancer AJCC v8;   Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IV Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IV Gastric Cancer AJCC v8;   Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8;   Postneoadjuvant Therapy Stage I Esophageal Adenocarcinoma AJCC v8;   Postneoadjuvant Therapy Stage I Esophageal Squamous Cell Carcinoma AJCC v8;   Postneoadjuvant Therapy Stage II Esophageal Adenocarcinoma AJCC v8;   Postneoadjuvant Therapy Stage II Esophageal Squamous Cell Carcinoma AJCC v8;   Postneoadjuvant Therapy Stage III Esophageal Adenocarcinoma AJCC v8;   Postneoadjuvant Therapy Stage III Esophageal Squamous Cell Carcinoma AJCC v8;   Postneoadjuvant Therapy Stage IIIA Esophageal Adenocarcinoma AJCC v8;   Postneoadjuvant Therapy Stage IIIA Esophageal Squamous Cell Carcinoma AJCC v8;   Postneoadjuvant Therapy Stage IIIB Esophageal Adenocarcinoma AJCC v8;   Postneoadjuvant Therapy Stage IIIB Esophageal Squamous Cell Carcinoma AJCC v8;   Postneoadjuvant Therapy Stage IV Esophageal Adenocarcinoma AJCC v8;   Postneoadjuvant Therapy Stage IV Esophageal Squamous Cell Carcinoma AJCC v8;   Postneoadjuvant Therapy Stage IVA Esophageal Adenocarcinoma AJCC v8;   Postneoadjuvant Therapy Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8;   Postneoadjuvant Therapy Stage IVB Esophageal Adenocarcinoma AJCC v8;   Postneoadjuvant Therapy Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8;   Stage 0 Colorectal Cancer AJCC v8;   Stage 0a Bladder Cancer AJCC v8;   Stage 0is Bladder Cancer AJCC v8;   Stage I Bladder Cancer AJCC v8;   Stage I Cervical Cancer AJCC v8;   Stage I Colorectal Cancer AJCC v8;   Stage I Ovarian Cancer AJCC v8;   Stage I Prostate Cancer AJCC v8;   Stage I Renal Cell Cancer AJCC v8;   Stage I Uterine Corpus Cancer AJCC v8;   Stage IA Cervical Cancer AJCC v8;   Stage IA Ovarian Cancer AJCC v8;   Stage IA Uterine Corpus Cancer AJCC v8;   Stage IA1 Cervical Cancer AJCC v8;   Stage IA2 Cervical Cancer AJCC v8;   Stage IB Cervical Cancer AJCC v8;   Stage IB Ovarian Cancer AJCC v8;   Stage IB Uterine Corpus Cancer AJCC v8;   Stage IB1 Cervical Cancer AJCC v8;   Stage IB2 Cervical Cancer AJCC v8;   Stage IC Ovarian Cancer AJCC v8;   Stage II Bladder Cancer AJCC v8;   Stage II Cervical Cancer AJCC v8;   Stage II Colorectal Cancer AJCC v8;   Stage II Ovarian Cancer AJCC v8;   Stage II Prostate Cancer AJCC v8;   Stage II Renal Cell Cancer AJCC v8;   Stage II Uterine Corpus Cancer AJCC v8;   Stage IIA Cervical Cancer AJCC v8;   Stage IIA Colorectal Cancer AJCC v8;   Stage IIA Ovarian Cancer AJCC v8;   Stage IIA Prostate Cancer AJCC v8;   Stage IIA1 Cervical Cancer AJCC v8;   Stage IIA2 Cervical Cancer AJCC v8;   Stage IIB Cervical Cancer AJCC v8;   Stage IIB Colorectal Cancer AJCC v8;   Stage IIB Ovarian Cancer AJCC v8;   Stage IIB Prostate Cancer AJCC v8;   Stage IIC Colorectal Cancer AJCC v8;   Stage IIC Prostate Cancer AJCC v8;   Stage III Bladder Cancer AJCC v8;   Stage III Cervical Cancer AJCC v8;   Stage III Colorectal Cancer AJCC v8;   Stage III Ovarian Cancer AJCC v8;   Stage III Prostate Cancer AJCC v8;   Stage III Renal Cell Cancer AJCC v8;   Stage III Uterine Corpus Cancer AJCC v8;   Stage IIIA Bladder Cancer AJCC v8;   Stage IIIA Cervical Cancer AJCC v8;   Stage IIIA Colorectal Cancer AJCC v8;   Stage IIIA Ovarian Cancer AJCC v8;   Stage IIIA Prostate Cancer AJCC v8;   Stage IIIA Uterine Corpus Cancer AJCC v8;   Stage IIIA1 Ovarian Cancer AJCC v8;   Stage IIIA2 Ovarian Cancer AJCC v8;   Stage IIIB Bladder Cancer AJCC v8;   Stage IIIB Cervical Cancer AJCC v8;   Stage IIIB Colorectal Cancer AJCC v8;   Stage IIIB Ovarian Cancer AJCC v8;   Stage IIIB Prostate Cancer AJCC v8;   Stage IIIB Uterine Corpus Cancer AJCC v8;   Stage IIIC Colorectal Cancer AJCC v8;   Stage IIIC Ovarian Cancer AJCC v8;   Stage IIIC Prostate Cancer AJCC v8;   Stage IIIC Uterine Corpus Cancer AJCC v8;   Stage IIIC1 Uterine Corpus Cancer AJCC v8;   Stage IIIC2 Uterine Corpus Cancer AJCC v8;   Stage IV Bladder Cancer AJCC v8;   Stage IV Cervical Cancer AJCC v8;   Stage IV Colorectal Cancer AJCC v8;   Stage IV Ovarian Cancer AJCC v8;   Stage IV Prostate Cancer AJCC v8;   Stage IV Renal Cell Cancer AJCC v8;   Stage IV Uterine Corpus Cancer AJCC v8;   Stage IVA Bladder Cancer AJCC v8;   Stage IVA Cervical Cancer AJCC v8;   Stage IVA Colorectal Cancer AJCC v8;   Stage IVA Ovarian Cancer AJCC v8;   Stage IVA Prostate Cancer AJCC v8;   Stage IVA Uterine Corpus Cancer AJCC v8;   Stage IVB Bladder Cancer AJCC v8;   Stage IVB Cervical Cancer AJCC v8;   Stage IVB Colorectal Cancer AJCC v8;   Stage IVB Ovarian Cancer AJCC v8;   Stage IVB Prostate Cancer AJCC v8;   Stage IVB Uterine Corpus Cancer AJCC v8;   Stage IVC Colorectal Cancer AJCC v8Interventions:   Procedure: Patient Monitoring;   Other: Questionnaire AdministrationSponsors:   City of Hope Medical Center;   National Cancer Institute (NCI)Recruiting

  • Nutrition in Gastrointestinal Tumors
    on July 17, 2020 at 4:00 pm

    Conditions:   Pancreatic Cancer;   Oesophageal Cancer;   Colon Cancer;   Liver Cancer;   Rectal Cancer;   Bile Duct Cancer;   GIST, Malignant;   Neuroendocrine Tumors;   Small Intestine Cancer;   Gastric CancerIntervention:   Other: No intervention - observational study onlySponsor:   University Medicine GreifswaldRecruiting

  • Health and Employment After Gastro Intestinal Surgery - HEAGIS1
    on July 10, 2020 at 4:00 pm

    Conditions:   Esophageal Neoplasms;   Stomach Neoplasm;   Colonic NeoplasmsIntervention:   Behavioral: Promotion of competences of participant involved in the management of the post operative periodSponsors:   University of Padova;   Humanitas Hospital, Italy;   Istituto Oncologico Veneto IRCCSRecruiting

  • Health and Employment After Gastro Intestinal Surgery - HEAGIS2
    on July 10, 2020 at 4:00 pm

    Conditions:   Esophageal Neoplasms;   Gastric Neoplasm;   Colon NeoplasmsIntervention:   Sponsors:   University of Padova;   Humanitas Hospital, Italy;   Istituto Oncologico Veneto IRCCSRecruiting

  • Real-Time Monitoring of Chemotherapy Side-Effects in Patients With Gastrointestinal Cancers, RT-CAMSS Study
    on June 29, 2020 at 4:00 pm

    Conditions:   Clinical Stage 0 Esophageal Adenocarcinoma AJCC v8;   Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage 0 Gastric Cancer AJCC v8;   Clinical Stage I Esophageal Adenocarcinoma AJCC v8;   Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage I Gastric Cancer AJCC v8;   Clinical Stage II Esophageal Adenocarcinoma AJCC v8;   Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage II Gastric Cancer AJCC v8;   Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8;   Clinical Stage IIA Gastric Cancer AJCC v8;   Clinical Stage IIB Gastric Cancer AJCC v8;   Clinical Stage III Esophageal Adenocarcinoma AJCC v8;   Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage III Gastric Cancer AJCC v8;   Clinical Stage IV Esophageal Adenocarcinoma AJCC v8;   Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage IV Gastric Cancer AJCC v8;   Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8;   Clinical Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage IVA Gastric Cancer AJCC v8;   Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8;   Clinical Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8;   Clinical Stage IVB Gastric Cancer AJCC v8;   Pathologic Stage 0 Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage 0 Gastric Cancer AJCC v8;   Pathologic Stage I Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage I Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage I Gastric Cancer AJCC v8;   Pathologic Stage IA Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IA Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IA Gastric Cancer AJCC v8;   Pathologic Stage IB Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IB Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IB Gastric Cancer AJCC v8;   Pathologic Stage IC Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage II Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage II Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage II Gastric Cancer AJCC v8;   Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IIA Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IIA Gastric Cancer AJCC v8;   Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IIB Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IIB Gastric Cancer AJCC v8;   Pathologic Stage III Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage III Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage III Gastric Cancer AJCC v8;   Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IIIA Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IIIA Gastric Cancer AJCC v8;   Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IIIB Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IIIB Gastric Cancer AJCC v8;   Pathologic Stage IIIC Gastric Cancer AJCC v8;   Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IV Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IV Gastric Cancer AJCC v8;   Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8;   Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8;   Pathologic Stage IVB Esophageal Squamous Cell Carcinoma AJCC v8;   Stage 0 Colorectal Cancer AJCC v8;   Stage 0 Pancreatic Cancer AJCC v8;   Stage I Colorectal Cancer AJCC v8;   Stage I Pancreatic Cancer AJCC v8;   Stage IA Pancreatic Cancer AJCC v8;   Stage IB Pancreatic Cancer AJCC v8;   Stage II Colorectal Cancer AJCC v8;   Stage II Pancreatic Cancer AJCC v8;   Stage IIA Colorectal Cancer AJCC v8;   Stage IIA Pancreatic Cancer AJCC v8;   Stage IIB Colorectal Cancer AJCC v8;   Stage IIB Pancreatic Cancer AJCC v8;   Stage IIC Colorectal Cancer AJCC v8;   Stage III Colorectal Cancer AJCC v8;   Stage III Pancreatic Cancer AJCC v8;   Stage IIIA Colorectal Cancer AJCC v8;   Stage IIIB Colorectal Cancer AJCC v8;   Stage IIIC Colorectal Cancer AJCC v8;   Stage IV Colorectal Cancer AJCC v8;   Stage IV Pancreatic Cancer AJCC v8;   Stage IVA Colorectal Cancer AJCC v8;   Stage IVB Colorectal Cancer AJCC v8;   Stage IVC Colorectal Cancer AJCC v8Interventions:   Other: Patient Monitoring System;   Other: Questionnaire Administration;   Other: ConsultationSponsors:   Thomas Jefferson University;   National Cancer Institute (NCI)Recruiting

To participate in a clinical trial, participants are asked to sign an informed consent document. This document outlines all the potential benefits and risks that may arise from the trial, as well as an explanation of the experimental treatment, and what will be expected from the volunteer (i.e., number of visits to the clinic or hospital, any in-patient stays, etc.) Most clinical trials also have inclusion and exclusion criteria that outline who can and cannot participate in the study and why.

If you are interested in participating in an esophageal cancer clinical trial your doctor will be able to tell you if you are a good candidate for one and may help you find a trial in your local area. Clinical trials are conducted by research centers, hospitals, and universities all across the country and many of them are always recruiting new volunteers.

Match to Esophageal Cancer Clinical Trials

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