Oklahoma Clinical Trials

A listing of Oklahoma clinical trials actively recruiting patient volunteers.

Bordered by no less than six states including Texas, Oklahoma is a major producer of oil, gas, and agricultural foodstuffs that also has robust aviation, energy, biotechnology, and telecom industries. It is the 20th largest state and sits near the geographical center of the country. Its biggest city and capital is Oklahoma City, followed by Tulsa, Norman, and Edmond. It was originally part of the French territory of “Louisiana,” becoming part of the U.S. in the Louisiana Purchase of 1803. Today, the 511-bed INTEGRIS Baptist Medical Center is one of the local leaders in acute care, surgery, diagnosis, and rehabilitation.

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890 trials found

A Study Assessing the Efficacy and Safety of CBP-307 in Subjects With Moderate to Severe Ulcerative Colitis (UC)

NCT04700449

This study will evaluate the efficacy and safety of CBP-307 in subjects with moderate to severe ulcerative colitis (UC).

Conditions: Moderate to Severe Ulcerative Colitis

Pulse Consumption and Bone Health

NCT04692298

This study will investigate the effects of the addition of 100 grams/day of cooked pulses (i.e. lentil, pinto beans, peas, chickpeas, kidney beans) to the diet of postmenopausal women for 12 weeks on gut health, metabolic outcomes and bone biomarkers.

Conditions: Menopause
Phase: Not Applicable

A Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD)

NCT04688164

This is an outpatient, 2-arm, Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of REL-1017 once daily (QD) as an adjunctive treatment of Major Depressive Disorder. Study participants will continue to take their current antidepressant therapy in addition to the study drug or placebo for the duration of the treatment period.

Conditions: Major Depressive Disorder

Diabetes Smoking Cessation Incentives Study

NCT04682067

The purpose of this study is to evaluate the feasibility of contingency management on improving smoking cessation among individuals with type 2 diabetes.

Conditions: Smoking Cessation, Diabetes Type 2
Phase: Not Applicable

Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm

NCT04671082

This is a double-blind, randomized, placebo-controlled, multicenter study of the efficacy and safety of tolperisone (a non-opioid) or placebo administered in subjects with pain due to acute back muscle spasm.

Conditions: Back Muscle Spasm, Back Pain, Back Strain, Back Spasm Upper, Muscle Spasm, Acute Pain

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

NCT04658862

The purpose of study is to compare bladder intact-event free survival (BI-EFS) in participants receiving TAR-200 in combination with cetrelimab versus concurrent chemoradiotherapy.

Conditions: Urinary Bladder Neoplasms

A 18-month Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Oral UCB0599 in Study Participants With Early-stage Parkinson's Disease

NCT04658186

The purpose of the study is to assess the safety and tolerability of UCB0599 and to demonstrate the superiority of UCB0599 over placebo with regard to clinical symptoms of disease progression over 12 and 18 months in participants diagnosed with early-stage Parkinson's Disease.

Conditions: Early-stage Parkinson's Disease

Discogenic Low Back Pain Registry

NCT04652687

Registry is to observe and trend patterns of care and outcomes for the standard of care treatments of discogenic chronic LBP.

Conditions: Discogenic Pain, Low Back Pain

A Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273 Vaccine in Adolescents 12 to <18 Years Old to Prevent COVID-19

NCT04649151

The mRNA-1273 vaccine is being developed to prevent COVID-19, the disease resulting from Severe Acute Respiratory Syndrome coronavirus (SARS-CoV-2) infection. The study is designed to primarily evaluate the safety and reactogenicity of a single dose level of mRNA-1273 vaccine administered in 2 doses 28 days apart to an adolescent population.

Conditions: SARS-CoV-2
Phase: Phase 2/3

Randomized Study in Children and Adolescents With Migraine: Acute Treatment

NCT04649242

The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.

Conditions: Migraine

Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder

NCT04641143

The study's purpose is to evaluate the efficacy and safety of troriluzole as adjunctive therapy compared to placebo in subjects with Obsessive Compulsive Disorder (OCD)

Conditions: Obsessive-Compulsive Disorder

A Study of LY3462817 in Participants With Rheumatoid Arthritis

NCT04634253

The reason for this study is to see if the study drug LY3462817 is safe and effective in participants with moderately to severely active rheumatoid arthritis (RA).

Conditions: Rheumatoid Arthritis