Texas is currently home to 5025 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry
Recruiting
The purpose of the HF2 (Hemodynamic Frontiers in Heart Failure) registry is to collect relevant patient-level demographic, clinical, laboratory, and hemodynamic data from patients implanted with pulmonary artery pressure sensor at participating centers to advance scientific knowledge about ambulatory hemodynamics monitoring and HF (Heart Failure) therapies. The data collected will be used for retrospective studies, quality improvement, identifying research cohorts, and member-initiated research.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
05/21/2024
Locations: Austin Heart, Austin, Texas
Conditions: Heart Failure
Protocol Title: Safety and Feasibility of Autologous CD34+ Hematopoietic Stem Cells Mobilization and Apheresis in Participants With RUNX1 Familial Platelet Disorder
Recruiting
To evaluate the safety and feasibility of collecting hematopoietic stem cells (HSC) in participants with RUNX1-FPD.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/21/2024
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: RUNX1 Familial Platelet Disorder
Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses
Recruiting
This will be an open-label, 3-visit, single-arm, dispensing clinical trial to evaluate visual acuity.
Gender:
All
Ages:
Between 40 years and 70 years
Trial Updated:
05/21/2024
Locations: Tyler Eye Associates, Tyler, Texas
Conditions: Visual Acuity
Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma
Recruiting
The goal of this study is to assess and compare the effectiveness of fluticasone furoate/umeclidinium bromide/vilanterol trifenatate (FF/UMEC/VI) with inhaled corticosteroids/long-acting beta-2 agonists (ICS/LABA) in adult participants with uncontrolled asthma
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/21/2024
Locations: GSK Investigational Site, Dallas, Texas
Conditions: Asthma
Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia
Recruiting
This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with hypertriglyceridemia (HTG). After providing informed consent eligible participants will be randomized to receive 4 doses (once every 3 months) of plozasiran or placebo and be evaluated for efficacy and safety.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: Juno Research LLC, Houston, Texas
Conditions: Hypertriglyceridemia
Study of Plozasiran in Adults With Severe Hypertriglyceridemia
Recruiting
This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with severe hypertriglyceridemia (SHTG). After providing informed consent eligible participants will be randomized to receive 4 doses (once every 3 months) of plozasiran or placebo, and be evaluated for efficacy and safety. After Month 12, eligible participants will be offered an opportunity to continue in an optional open-label extension under a separate protocol.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: Diabetes and Thyroid Center of Fort Worth, Fort Worth, Texas
Conditions: Severe Hypertriglyceridemia
A Study of CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive Disorder
Recruiting
The study is a Phase 2, double-blind, randomized, placebo-controlled study in Major Depressive Disorder (MDD) participants with an inadequate response to standard antidepressants The objective of the study is to assess CLE-100 (oral esketamine) for the treatment of MDD in participants currently treated with an oral antidepressant medication and who have an inadequate response to at least 2 antidepressants.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/21/2024
Locations: Clinical Site 106, DeSoto, Texas
Conditions: Adjunctive Treatment of Major Depressive Disorder (MDD)
A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer
Recruiting
The main purpose of this study is to compare the disease-free survival between participants receiving treatment with TAR-210 versus investigator's choice of intravesical chemotherapy for treatment of intermediate-risk NMIBC.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: Urology Austin, Austin, Texas
Conditions: Non-Muscle Invasive Bladder Cancer
A Phase 3 Study to Evaluate the Efficacy and Safety of Efgartigimod IV in Patients With Acetylcholine Receptor Binding Antibody Seronegative Generalized Myasthenia Gravis
Recruiting
The primary purpose of this study is to measure the efficacy and safety of efgartigimod intravenously (IV) compared to placebo in participants with Acetylcholine Receptor Binding Antibody (AChR-Ab) seronegative Generalized Myasthenia Gravis (gMG). Other objectives are to assess long-term efficacy, safety, and tolerability of efgartigimod. Study will consist of: Screening Part A: participants will be randomized to receive either efgartigimod IV or placebo Part B: participants completing part A... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: National Neuromuscular Research Institute, Austin, Texas
Conditions: Generalized Myasthenia Gravis
Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder
Recruiting
Hypothesis: Will the use of tDCS brain modulation in the cerebellum assist in restricted behaviors, social cognition and cognitive flexibility in women with anorexia nervosa in addition to other therapies? Primary Outcomes: To observe the impacts and outcomes of cerebellar transcranial direct current stimulation (tDCS) on social behaviors measured by Cyberball and Trust Game. To observe the neuropsychological impacts of cerebellar tDCS through fMRI imaging as well as looking at the Region of I... Read More
Gender:
Female
Ages:
Between 15 years and 30 years
Trial Updated:
05/21/2024
Locations: UT Southwestern Multispecialty Psychiatry Clinic, Dallas, Texas
Conditions: Anorexia Nervosa
Study of V117957 in Interstitial Cystitis/Bladder Pain Syndrome
Recruiting
The purpose of this study is to evaluate the safety, tolerability and efficacy of V117957 in subjects with interstitial cystitis/bladder pain syndrome, compared to placebo.
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: Epic Clinical Research, Lewisville, Texas
Conditions: Interstitial Cystitis/Bladder Pain Syndrome
Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)
Recruiting
The purpose of this study is to investigate the efficacy and safety of retatrutide compared with semaglutide in participants with Type 2 Diabetes and inadequate glycemic control with metformin with or without sodium-glucose cotransporter-2 inhibitor (SGLT2i). The study will last about 26 months and may include up to 24 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/21/2024
Locations: Dallas Diabetes Research Center, Dallas, Texas
Conditions: Diabetes Mellitus, Type 2