Indiana Clinical Trials

A listing of Indiana clinical trials actively recruiting patient volunteers.

Indiana is about more than swashbuckling archaeologists. The capital, Indianapolis, is home to the famous Indianapolis Motor Speedway and Indy 500. Other great cities in the state include Evansville, Fort Wayne, and Bloomington. Indiana is one of the nation’s leaders in the automotive industry and has seen some of the strongest manufacturing job growth nationwide. Oddly enough, it is also one of the top states in producing professional basketball players. Those seeking quality healthcare in Indiana have lots of options, including Methodist Hospital in Indianapolis, part of Indiana University Health. It has the largest neuroscience critical care unit in America.

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1287 trials found

Comparison of Adenoma Detection Rate With ENDOCUFF VISION® vs. G-EYE®


The study is intended to compare the detection rate obtained by performing G-EYE® high definition colonoscopy vs. the detection rate obtained by performing ECV high definition colonoscopy.

Conditions: Adenoma, Colorectal Cancer
Phase: Not Applicable

A Study of Axatilimab at 3 Different Doses in Patients With Chronic Graft Versus Host Disease (cGVHD)


AGAVE-201 is a Phase 2 study to evaluate the efficacy, safety, and tolerability of axatilimab at 3 different dose levels in patients with recurrent or refractory active chronic graft versus host disease (cGVHD) who have received at least 2 prior lines of systemic therapy due to progression of disease, intolerability or toxicity.

Conditions: Chronic Graft-versus-host-disease

The Prevalence of Hypoesthesia Related Keratitis in Ocular Graft Vs. Host Disease (GVHD) Patients


The Investigators hypothesize that the recalcitrant nature of ocular GVHD may be related to corneal nerve damage and corneal hypoesthesia. The investigators aim to study the prevalence of corneal hypoesthesia in GVHD patients and its correlation with ocular surface changes.

Conditions: Ocular GVHD

Facilitators and Barriers to Cancer Screening: Stakeholder Perspectives on Implementation


The rate of screening for colorectal cancer (CRC) in the U.S. remains low (under 65%), meaning that thousands of people die of colorectal cancer unnecessarily. Colorectal cancer screening tests range from more invasive and very sensitive for polyps and cancer (colonoscopy) to less invasive and less sensitive (e.g., fecal immunochemical testing (FIT)). Screening rates go up when patients consider all these tests, not just colonoscopy. Informing patients about their options for CRC screening could ...

Conditions: Colorectal Cancer Screening

TTHX1114(NM141) in Combination With DWEK/DSO


Open label, single-treatment, with a concurrent non-treatment control

Conditions: Fuchs' Endothelial Dystrophy, Fuchs Dystrophy, Fuchs

Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm


This is a double-blind, randomized, placebo-controlled, multicenter study of the efficacy and safety of tolperisone (a non-opioid) or placebo administered in subjects with pain due to acute back muscle spasm.

Conditions: Back Muscle Spasm, Back Pain, Back Strain, Back Spasm Upper, Muscle Spasm, Acute Pain

Pandemic-adapted Caries Care Multicentre Case Series


TThe current understanding of dental caries has not been completely transferred into the clinical practice to control caries lesion progression (severity / activity) and the individual risk of caries. This situation led to the development of the CariesCare International CCI Caries Management System (2018), derived from ICCMS™- International Caries Classification and Management System (2012) and the ICDAS - International Caries Detection and Assessment System (2002) in a consensus among more than ...

Conditions: Dental Caries in Children

Study To Assess Efficacy, Safety, Tolerability And Pharmacokinetics Of PF-07038124 Ointment In Participants With Atopic Dermatitis Or Plaque Psoriasis


This study is being conducted to provide data on efficacy, safety, tolerability and PK of PF-07038124 ointment versus vehicle control in the treatment of mild to moderate AD and mild to moderate plaque psoriasis.

Conditions: Atopic Dermatitis, Plaque Psoriasis

ASCO Survey on COVID-19 in Oncology (ASCO) Registry


The American Society of Clinical Oncology (ASCO) Survey on Coronavirus 2019 (COVID-19) in Oncology Registry (ASCO Registry) aims to help the cancer community learn more about the patterns of symptoms and severity of COVID-19 among patients with cancer, as well as how COVID-19 is impacting the delivery of cancer care and patient outcomes. The ASCO Registry is designed to collect both baseline and follow-up data on how the virus impacts cancer care and cancer patient outcomes during the COVID-19 p ...

Conditions: Neoplasms, Coronavirus

A Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273 Vaccine in Adolescents 12 to <18 Years Old to Prevent COVID-19


The mRNA-1273 vaccine is being developed to prevent COVID-19, the disease resulting from Severe Acute Respiratory Syndrome coronavirus (SARS-CoV-2) infection. The study is designed to primarily evaluate the safety and reactogenicity of a single dose level of mRNA-1273 vaccine administered in 2 doses 28 days apart to an adolescent population.

Conditions: SARS-CoV-2
Phase: Phase 2/3

A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Dry Age-related Macular Degeneration


This study is designed to investigate the safety, PK/PD, biomarker and early clinical effects of repeat GEM103 IVT injections.

Conditions: Dry Age-related Macular Degeneration, Geographic Atrophy, Macular Degeneration, Retinal Disease, Retinal Degeneration

The Combined Effect of Chronic Cannabis Use and Subconcussive Head Impacts on Brain Health


The purpose of this pilot study is to better understand the effects of chronic cannabis (THC) use on the neural responses to subconcussive head impacts, as a form of repetitive soccer headings. The study is designed to identify the physiological changes of cannabis using cohort (THC) and compare it to a nonusing cohort in order to see if the responses to 20 controlled bouts of soccer headings are exacerbated by the chronic cannabis use, diminished to less of a response, or unchanged, through an ...

Conditions: Concussion, Mild
Phase: Not Applicable