Colorado Clinical Trials

A listing of Colorado clinical trials actively recruiting patient volunteers.

One of the biggest domestic vacation destinations in the U.S., Colorado is perhaps best known for its world class skiing. Denver, Colorado Springs, Boulder, and Aspen are among the major cities, with tourism centered on the Aspen area and the smaller city of Vail. Denver International Airport is one of America’s busiest airports and, at 53 square miles, is twice the size of Manhattan. Colorado has also a fast-moving culinary scene: It’s behind only Washington and California in total number of breweries. The Denver area has some of the nation’s top hospitals, with University of Colorado Hospital leading in size.

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1870 trials found

Study to Evaluate the Benefit of RUCONEST in Improving Neurological Symptoms in Post COVID-19 Infection

NCT04705831

Randomized, Double Blind, Placebo Controlled, Proof-of-Concept Study to Evaluate the Benefit of RUCONEST in Improving Neurological Symptoms in Post-SARS-CoV-2 Infection.

Conditions: Post-Viral Fatigue Syndrome, Post-Viral Disorder (Disorder), Covid19

Evaluation of Geistlich Fibro-Gide® in Comparison to CTG for the Treatment Around Implants

NCT04703738

This double blind, randomized, parallel study evaluates the non-inferiority of Geistlich Fibro-Gide® in comparison to connective tissue graft for soft tissue volume augmentation around dental implants

Conditions: Soft Tissue Defect
Phase: Not Applicable

Defining the Genetic Etiology of Suppurative Lung Disease in Children and Adults

NCT04702243

The investigators will utilize a systematic approach for the diagnostic evaluation of patients to identify characteristics which may distinguish between Primary Immunodeficiency (PID) disorders versus Primary Ciliary Dyskinesia (PCD).

Conditions: Primary Ciliary Dyskinesia, Primary Immune Deficiency, Kartagener Syndrome

Feasibility of a Goal-based Agenda Setting Intervention

NCT04696484

This study aims to assess the feasibility of a new, brief intervention, the 'coopeRATE Prompt', for informing conversations between patients and physicians in routine tele-health and in-person adult Cystic Fibrosis (CF) care. The coopeRATE Prompt is two questions designed to elicit patients' concerns and goals to facilitate collaborative goal setting within the health care visit. This is a prospective single arm study that will be conducted at four CF care centers in the United States.

Conditions: Cystic Fibrosis, Chronic Disease
Phase: Not Applicable

A Study of PY314 in Subjects With Advanced Solid Tumors

NCT04691375

A Phase 1a/1b Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PY314 as a Single Agent and In Combination with Pembrolizumab in Subjects with Advanced Solid Tumors

Conditions: Advanced Solid Tumor

A Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD)

NCT04688164

This is an outpatient, 2-arm, Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of REL-1017 once daily (QD) as an adjunctive treatment of Major Depressive Disorder. Study participants will continue to take their current antidepressant therapy in addition to the study drug or placebo for the duration of the treatment period.

Conditions: Major Depressive Disorder

DreamKit Diagnostic Validation

NCT04671342

This study has been developed in order to demonstrate diagnostic efficacy of the DreamKit device against polysomnography.

Conditions: Sleep Apnea, Obstructive, Sleep Apnea, Central
Phase: Not Applicable

Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm

NCT04671082

This is a double-blind, randomized, placebo-controlled, multicenter study of the efficacy and safety of tolperisone (a non-opioid) or placebo administered in subjects with pain due to acute back muscle spasm.

Conditions: Back Muscle Spasm, Back Pain, Back Strain, Back Spasm Upper, Muscle Spasm, Acute Pain

A Sample Collection Study Utilizing DermTech's Non-invasive Adhesive Patch Biopsy Kits

NCT04668846

This sample collection study will recruit subjects with a variety of skin conditions from up to 15 geographically dispersed sites in the United States. Skin samples will be collected with the DermTech Adhesive Patch Kit from both lesional and non-lesional skin. Subjects may also be asked to return at a future data for additional collections. Collected skin samples will be analyzed for gene expression information, DNA and the microbiome.

Conditions: Dermatologic Diseases

COVID-19 Study Assessing the Virologic Efficacy of REGN10933+REGN10987 Across Different Dose Regimens in Adult Outpatients With SARS-CoV-2 Infection

NCT04666441

The primary objective of the study is to assess the virologic efficacy of REGN10933+REGN10987 across different intravenous and subcutaneous doses compared to placebo. The secondary objectives of the study are: To evaluate additional indicators of virologic efficacy of REGN10933+REGN10987 compared to placebo To evaluate the safety and tolerability of REGN10933+REGN10987 compared to placebo To assess the concentrations of REGN10933 and REGN10987 in serum over time

Conditions: COVID-19

LYT-200 Alone and in Combination With Chemotherapy or Anti-PD-1 in Patients With Metastatic Solid Tumors

NCT04666688

A Phase 1/2 Open-label, Multi-center Study of the Safety, Pharmacokinetics, and Anti-tumor Activity of LYT-200 Alone and in Combination with Chemotherapy or Anti-PD-1 in Patients with Metastatic Solid Tumors

Conditions: Metastatic Cancer, Solid Tumor, Cholangiocarcinoma, Colorectal Cancer, Pancreatic Cancer
Phase: Phase 1/2

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

NCT04658862

The purpose of study is to compare bladder intact-event free survival (BI-EFS) in participants receiving TAR-200 in combination with cetrelimab versus concurrent chemoradiotherapy.

Conditions: Urinary Bladder Neoplasms