The state of Alabama currently has 15 active clinical trials seeking participants for Alzheimer's Disease research studies. These trials are conducted in various cities, including Birmingham, Mobile, Huntsville and Anniston.
DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease
Recruiting
This is an open label study to treat dominantly inherited Alzheimer's disease (DIAD) mutation carrier participants from the DIAN-TU-001 gantenerumab Open Label Extension (OLE) period with lecanemab to determine the effects of amyloid removal on age of onset and clinical progression compared to external controls, if amyloid plaque as measured by amyloid PET can be fully removed in DIAD, and the effects of amyloid removal on biomarkers of disease progression.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/01/2024
Locations: University of Alabama in Birmingham, Birmingham, Alabama
Conditions: Alzheimer's Disease, Dementia, Alzheimer's Disease, Familial
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001
Recruiting
The purpose of this study is to assess the safety, tolerability, biomarker, cognitive and clinical efficacy of investigational products in participants with an Alzheimer's disease-causing mutation by determining if treatment with the study drug slows the rate of progression of cognitive/clinical impairment or improves disease-related biomarkers.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/01/2024
Locations: University of Alabama in Birmingham, Birmingham, Alabama
Conditions: Alzheimers Disease, Dementia, Alzheimers Disease, Familial
Juice Plus Supplement Clinical Trial
Recruiting
The study is designed to determine whether encapsulated fruit and vegetable juice concentrates can improve biological indicators of cognitive and multiple dimensions of memory and learning.
Gender:
All
Ages:
Between 55 years and 90 years
Trial Updated:
04/05/2021
Locations: University of Alabama, North East Medical Building, Tuscaloosa, Alabama +1 locations
Conditions: Cognitive Impairment, Alzheimer Disease, Early Onset, Mild Cognitive Impairment