There are currently 80 clinical trials in Huntsville, Alabama looking for participants to engage in research studies. Trials are conducted at various facilities, including Heart Center Research, Llc, Clearview Cancer Institute, Medical Affiliated Research Center, Inc and Pfizer Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization
NCT05064540
Recruiting
Prospective, randomized, multi-center study designed to evaluate the outcomes of commercially available contemporary EVAR in a real-world population. Patients will be randomized into two device cohorts and compared across the primary endpoints. Patients will be followed procedurally to discharge, at 1, 6, 12 months and annually through to 5 years (total follow-up commitment).
Gender:
ALL
Ages:
21 years and above
Trial Updated:
06/05/2025
Locations: Huntsville Hospital, Huntsville, Alabama
Conditions: AAA, AAA - Abdominal Aortic Aneurysm
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A Study of Zigakibart in Adults With IgA Nephropathy
NCT05852938
Recruiting
Safety and Efficacy of BION-1301 in Adults with IgA Nephropathy
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/29/2025
Locations: Nephrology Consultants, LLC, Huntsville, Alabama
Conditions: IgA Nephropathy, Immunoglobulin A Nephropathy
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MicroRNA Correlates of Childhood Maltreatment and Suicidality
NCT04923685
Recruiting
This is a research study to find out if childhood trauma and stress are associated with depression or suicidal risk. The study will assess the effects of both short-term and long-term stress on biomarker (e.g. miRNA \[MiRNA\]) levels. miRNAs are a type of RNA (genetic material that is translated into protein) that are found in throughout the body and blood. They are called microRNA because their size is much smaller than typical RNA molecules. miRNAs are highly responsive to environment. This re... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
05/12/2025
Locations: UAB Huntsville Regional Medical Campus, Huntsville, Alabama
Conditions: Major Depressive Disorder, Suicidal Ideation
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Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA
NCT04955795
Recruiting
This study is designed to examine the efficacy of a brief intervention plus a cognitive-behavioral intervention compared to brief intervention alone to address unhealthy alcohol use and comorbid mental health symptoms to improve HIV outcomes among people living with HIV in Alabama.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
05/01/2025
Locations: Thrive, Huntsville, Alabama
Conditions: Hiv, Alcohol Problem
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In-Office Clinical Study of the Solo+ TTD
NCT05741333
Recruiting
The objective of this study is to evaluate the safety and effectiveness of the Solo+ Tympanostomy Tube Device (Solo+ TTD) for the placement of tympanostomy tubes in paediatric patients undergoing a tympanostomy procedure.
Gender:
ALL
Ages:
Between 6 months and 13 years
Trial Updated:
04/15/2025
Locations: North Alabama ENT, Huntsville, Alabama
Conditions: Ear Infection, Otitis Media
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A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder
NCT05729373
Recruiting
A clinical study that will meaure how well SEP-363856 works and how safe it is in adults with Generalized Anixety Disorder. This study will be accepting both male and female subjects between the ages of 18 years and 65 years old. The study will be held in Approximately 50 global study centers and approximately 15 additional centers for a separate Japan population. Participation in the study can be up to approximately 12 weeks.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
04/09/2025
Locations: University of Alabama at Birmingham, Huntsville, Alabama
Conditions: Generalized Anxiety Disorder
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Absorption and Tolerability of Injectable Administration of Niagen®+, as Compared to NAD+
NCT06919328
Recruiting
This study evaluates the subjective effects of injection administration of NR on healthy adult populations.
Gender:
ALL
Ages:
Between 40 years and 65 years
Trial Updated:
04/07/2025
Locations: Nutraceuticals Research Institute, Huntsville, Alabama
Conditions: Healthy Aging
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The Effectiveness of a Proprietary of a Botanical Extract on Sleep Quality
NCT06894108
Recruiting
The purpose of this study is to evaluate the efficacy and superiority of a botanical based sleep product on sleep quality as compared to melatonin, among healthy female participants.
Gender:
FEMALE
Ages:
Between 35 years and 55 years
Trial Updated:
03/19/2025
Locations: Nutraceuticals Research Institute, Huntsville, Alabama
Conditions: Sleep
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Amplatzer Amulet LAAO Vs. NOAC
NCT04226547
Recruiting
The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device ("Device Group") and a commercially available NOAC medication ("Cont... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: Heart Center Research, LLC, Huntsville, Alabama
Conditions: Atrial Fibrillation, Stroke, Bleeding
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Study of the Research Medicine CIN-103 in Adults with Irritable Bowel Syndrome with Predominant Diarrhea (IBS-D).
NCT06153420
Recruiting
The goal of this clinical trial is to evaluate if the study drug, CIN-103, can help reduce the symptoms associated with irritable bowel syndrome with predominant diarrhea (IBS-D) in adult patients. The main questions it aims to answer are: * To evaluate the efficacy of CIN-103 on symptoms of IBS-D when given to patients with IBS-D compared to a placebo. * To evaluate the safety and tolerability of CIN-103 when given to patients with IBS-D compared to a placebo Participants will attend the foll... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/21/2025
Locations: Clinical Research Associates, LLC, Huntsville, Alabama
Conditions: Irritable Bowel Syndrome With Diarrhea
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A Phase 2 Study of MZE829 in Adults with APOL1 Kidney Disease
NCT06830629
Recruiting
This is purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/12/2025
Locations: Apogee Clinical Research, Huntsville, Alabama
Conditions: Proteinuric Kidney Disease
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A Real-World Comparative Study of Donanemab (LY3002813) Plus Usual Care Versus Usual Care Alone in US Participants With Early Symptomatic Alzheimer's Disease
NCT06566170
Recruiting
The main purpose of this study is to evaluate the long-term effectiveness of donanemab plus usual care versus usual care alone in participants with early symptomatic AD. The study will employ a prospective, observational cohort design with participant management resembling real-world practice to the greatest extent possible via prospective assessments and linkage to historical and prospective electronic health records. The study will last about 273 weeks and may include up to 28 visits.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
02/11/2025
Locations: Rehabilitation & Neurological Services, Huntsville, Alabama
Conditions: Alzheimer Disease
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