There are currently 486 clinical trials in Little Rock, Arkansas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Arkansas for Medical Sciences, Arkansas Children's Hospital, GSK Investigational Site and Arkansas Cancer Research Center at University of Arkansas for Medical Sciences. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Nutritional Therapy for Delirium in Elderly Hospitalized Subjects
NCT05066503
Recruiting
The investigators have developed a proprietary blend of amino acids that they think will help to prevent or reduce the severity of delirium in older people who are hospitalized for certain infections. In this study, up to 45 people will be enrolled. 15 will be asked to drink this blend twice a day for up to 4 days, and 15 will drink a placebo (sugar water) for the same time period. The other 15 subjects will be non-delirious control subjects who do not consume any study products.
Gender:
All
Ages:
60 years and above
Trial Updated:
12/20/2023
Locations: UAMS Center on Aging, Little Rock, Arkansas
Conditions: Subacute Delirium
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Glowing and Expecting Follow Up
NCT03108001
Recruiting
This study will help us learn more about how a mother's health during pregnancy may influence her child's growth and development later in life.
Gender:
All
Ages:
Between 5 years and 14 years
Trial Updated:
12/18/2023
Locations: Arkansas Children's Nutrition Center, Little Rock, Arkansas
Conditions: Healthy
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Beginnings Study Follow up
NCT03108014
Recruiting
This study will help us learn more about how early infant diet may influence child's growth and development at age 14.
Gender:
All
Ages:
Between 14 years and 14 years
Trial Updated:
12/18/2023
Locations: Arkansas Children's Nutrition Center, Little Rock, Arkansas
Conditions: Healthy
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A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical Pain
NCT05773846
Recruiting
PRF-110 is a viscous, yellowish clear oily solution of ropivacaine intended for administration into surgical sites to provide post-operative analgesia. The pharmacokinetic profile for PRF-110 suggests that its effect could last up to 72 hours. This is A Phase 3, Randomized, Double-Blind, Saline Placebo- and Active-Controlled, Multicenter Study to Evaluate the Analgesic Efficacy and Safety of Intra-operative Administration of PRF-110 Following Unilateral Bunionectomy
Gender:
All
Ages:
18 years and above
Trial Updated:
12/15/2023
Locations: Woodland International Research Group, Little Rock, Arkansas
Conditions: Bunion
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Prospective Study of Pregnancy in Women With Cystic Fibrosis
NCT04828382
Recruiting
In this study, the investigators aim to evaluate changes in lung function in women with cystic fibrosis (CF) during pregnancy and for 2 years after pregnancy based on exposure to highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators.
Gender:
Female
Ages:
16 years and above
Trial Updated:
12/12/2023
Locations: University of Arkansas for Medical Sciences, Little Rock, Arkansas
Conditions: Pregnancy Related, Cystic Fibrosis
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The Human Stress Response in a Simulated ED Setting
NCT04317482
Recruiting
Stress is important for health. As emergency departments (EDs) are often stressful places, a better understanding of the human stress response is important for understanding how and why patients respond as they do when they come to the ED. Since the investigators cannot take up space in the ED for research, the investigators will instead recruit 20 methamphetamine-using participants who are not currently in treatment and 10 healthy adult matched participants to a simulated ED room in the Univers... Read More
Gender:
All
Ages:
Between 21 years and 55 years
Trial Updated:
12/11/2023
Locations: University of Arkansas for Medical Sciences, Little Rock, Arkansas
Conditions: Stress Physiology, Stress Reaction, Substance Use Disorders, Methamphetamine-dependence, Stress, Emotional
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CureDuchenne Link®: A Resource for Research
NCT04972604
Recruiting
CureDuchenne link is a data hub comprised of integrated biospecimens, clinical data, and self- and/or caregiver-reported information from participants. Anyone over 4 weeks old who has been diagnosed with DMD or BMD or who is a carrier of DMD or BMD can join. Parents or legal guardians can sign up their child(ren).
Gender:
All
Ages:
4 weeks and above
Trial Updated:
12/08/2023
Locations: Arkansas Children's Hospital, Little Rock, Arkansas
Conditions: Duchenne Muscular Dystrophy, Becker Muscular Dystrophy
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In Vivo Real-time Detection of Circulating Melanoma Cells
NCT01776905
Recruiting
The objective of this clinical trial is to determine whether a Photoacoustic flow cytometry (PAFC)-based prototype device can detect circulating tumor cells (CTCs) in the blood of melanoma patients in vivo, in real time, and do so at detection limits at least one order of magnitude below the detection limits of currently existing ex vivo methods.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
12/04/2023
Locations: University of Arkansas for Medical Sciences, Little Rock, Arkansas
Conditions: Melanoma
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CapTemY90 for Grade 2 NET Liver Metastases
NCT04339036
Recruiting
This is a Phase 2 evaluation of hepatic-progression free survival among patients with Grade 2 liver-dominant NET metastases undergoing combination therapy with CapTem and Y90 radioembolization.The hypothesis is to confirm safety and to assess if disease control is improved relative to expectation from either therapy alone.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/01/2023
Locations: CARTI Cancer Center, Little Rock, Arkansas
Conditions: Neuroendocrine Tumor Grade 2, Neuroendocrine Tumors
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Casting vs Bracing for Idiopathic Early-Onset Scoliosis
NCT04500041
Recruiting
Comparison of casting and bracing for the treatment of idiopathic early onset scoliosis
Gender:
All
Ages:
Between 12 months and 36 months
Trial Updated:
11/27/2023
Locations: Arkansas Children's Hospital, Little Rock, Arkansas
Conditions: Scoliosis Idiopathic, Early-Onset Scoliosis Deformity of Spine
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CHaractErizing CFTR Modulated Changes in Sweat Chloride and Their Association With Clinical Outcomes
NCT03350828
Recruiting
This is a multicenter, cross-sectional, cohort study which will collect contemporary sweat chloride (SC) values from approximately 5000 Cystic Fibrosis (CF) patients prescribed and currently receiving commercially approved Cystic Fibrosis transmembrane conductance regulator (CFTR) modulator therapies.
Gender:
All
Ages:
4 months and above
Trial Updated:
11/21/2023
Locations: University of Arkansas for Medical Sciences, Little Rock, Arkansas
Conditions: Cystic Fibrosis
Register for Updates
The Pediatric Anesthesia Quality Improvement Project
NCT00674388
Recruiting
The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics. An analysis of each adverse event will be performed and entered into the database. From this information we will devise strategies to prevent these adverse events.
Gender:
All
Ages:
21 years and below
Trial Updated:
11/20/2023
Locations: Arkansas Children's Hospital, Little Rock, Arkansas
Conditions: Surgery, Anesthesia, Children
Register for Updates