There are currently 1854 clinical trials in Los Angeles, California looking for participants to engage in research studies. Trials are conducted at various facilities, including Cedars-Sinai Medical Center, USC / Norris Comprehensive Cancer Center, Childrens Hospitla Los Angeles and University of California Los Angeles. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Optimizing Treatment of Adhesive Small Bowel Obstruction
NCT06182319
Recruiting
Small bowel obstruction (SBO) is one of the most common causes of serious gastrointestinal disease in the US. Adhesion-related SBO (aSBO) is usually treated by the placement of a nasogastric tube (NGT) to decompress the stomach, administration of intravenous (IV) fluids and observation by a surgical team. The purpose of this feasibility study is to determine the potential for implementation of treatment protocols for aSBO and determine the feasibility of randomizing patients with aSBO to receiv... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, California
Conditions: Adhesive Small Bowel Obstruction
Register for Updates
Efficacy of Trigeminal Nerve Stimulation for ADHD
NCT05374187
Recruiting
This study is a large multisite randomized clinical trial to asses the efficacy of external trigeminal nerve stimulation (TNS), a novel, minimal risk, non-invasive neuromodulation treatment, for ADHD in children ages 7-12 years old (N=180). Study hypotheses address potential differences in ADHD symptoms over 4 weeks treatment with active vs. sham TNS in an expanded multi-site investigation; whether resting state fronto-parietal connectivity mediates TNS impact on ADHD symptoms; if changes in fr... Read More
Gender:
ALL
Ages:
Between 7 years and 12 years
Trial Updated:
05/07/2024
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Attention-Deficit Hyperactivity Disorder
Register for Updates
Active Surveillance for Cancer of the Prostate (ASCaP)
NCT00949819
Recruiting
Active Surveillance (A.S.) of prostate cancer (CaP) is the systematic monitoring of men with low-risk, localized lesions, with curative treatment of those whose tumors show substantial progression. A.S. is different from Watchful Waiting (W.W.), which is the palliative treatment of men with progressive prostate cancer.
Gender:
MALE
Ages:
Between 30 years and 85 years
Trial Updated:
05/06/2024
Locations: University of California Los Angeles, Los Angeles, California
Conditions: Prostate Cancer
Register for Updates
Expression of Stress Markers During Meth Treatment (EXPRESS+)
NCT05558345
Recruiting
This is a non-randomized behavioral trial that aims to investigate whether changes in inflammatory and type I IFN expression coincide with changes in methamphetamine use and viral load over the course of 12 weeks in HIV-positive people assigned male at birth with and without methamphetamine use disorder.
Gender:
MALE
Ages:
Between 18 years and 45 years
Trial Updated:
05/06/2024
Locations: UCLA Vine Street Clinic, Los Angeles, California
Conditions: Substance-Related Disorders, HIV
Register for Updates
Impact of Protect Your Colon™ on CRC Screening
NCT05929820
Recruiting
The purpose of the research is to assess the impact of Protect Your Colon™, a colorectal cancer (CRC) screening decision aid, on patients' CRC screening behaviors. The Investigators hypothesize that Protect Your Colon™, through optimizing shared decision making, will lead to selection of a test that accurately matches patients' values and increase CRC screening uptake. To test this hypothesis, the investigators will conduct a pilot randomized controlled trial (RCT) to assess if provision of Prot... Read More
Gender:
ALL
Ages:
Between 45 years and 75 years
Trial Updated:
05/06/2024
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Colorectal Cancer Screening
Register for Updates
Trazodone vs. Quetiapine for the Treatment of ICU Delirium
NCT05307003
Recruiting
This is a single-center, prospective observational pilot study. The objective of this study is to evaluate the effectiveness of trazodone as compared to quetiapine, in the management of ICU delirium in adult (\>=18 years old) surgical and medical ICU patients. The investigators will compare outcomes such as delirium duration, delirium-free days, coma-free days, in-hospital mortality, 28-day mortality, hospital length of stay (LOS), ICU LOS, mechanical ventilator days, complications, adverse effe... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Keck Hospital of the University of Southern California, Los Angeles, California
Conditions: Delirium, Delirium of Mixed Origin, Delirium, Sepsis Associated, Delirium in Old Age, Delirium Confusional State, Psych, Morality, Treatment Side Effects
Register for Updates
In Line Aerosol Nebulization With High Flow
NCT05880836
Recruiting
The objective of ILAN is to assess the safety, feasibility and bronchodilator efficacy of in-line bronchodilator nebulizer delivery with VMN via HFNC system in hypoxemic respiratory failure patients treated with bronchodilators and compare this method to standard-nebulization using a jet nebulizer with a facial mask. The investigators hypothesized that aerosol nebulization using HFNC/VMN represents safer and more convenient approach in hypoxemic respiratory failure patients in comparison to conv... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: Ronald Reagan Medical Center at UCLA, Los Angeles, California
Conditions: Hypoxemic Respiratory Failure, Airway Obstruction
Register for Updates
Writing About Experiences and Health in Older Adults II
NCT05524597
Recruiting
UCLA researchers looking for healthy older adults (aged 65+) to participate in a study investigating how writing about experiences can affect your brain and body. Once a week for 6 weeks, participants will write about their experiences and fill out online questionnaires. Participants will also come to the UCLA campus to complete a neuroimaging session (fMRI), provide a blood spot sample, and fill out questionnaires 2 times: once prior to the 6-week writing period and once immediately after the... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
05/06/2024
Locations: Center for Cognitive Neuroscience, Los Angeles, California
Conditions: Social Psychology
Register for Updates
Bioresorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers
NCT06403605
Recruiting
This study is a prospective, multi-center, randomized controlled trial designed to collect patient outcome data on 2 commercially available SOC treatments for Diabetic Foot Wounds.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: LA Foot and Ankle, Los Angeles, California
Conditions: Diabetic Foot Ulcer, Ulcer Foot, Diabetic Foot
Register for Updates
S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer
NCT04155034
Recruiting
This phase III trial studies magnetic resonance imaging (MRI) surveillance and prophylactic cranial irradiation (PCI) to see how well they work compared to MRI surveillance alone in treating patients with small cell lung cancer. MRI scans are used to monitor the possible spread of the cancer with an MRI machine over time. PCI is radiation therapy that is delivered to the brain in hopes of preventing spread of cancer into the brain. The use of brain MRI alone may reduce side effects of receiving... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/02/2024
Locations: Los Angeles County-USC Medical Center, Los Angeles, California +1 locations
Conditions: Extensive Stage Lung Small Cell Carcinoma, Limited Stage Lung Small Cell Carcinoma, Lung Small Cell Carcinoma
Register for Updates
Diabetes RElated to Acute Pancreatitis and Its Mechanisms
NCT05197920
Recruiting
The overriding objective of DREAM is to conduct a prospective longitudinal (36 months) observational clinical study to investigate the incidence, etiology, and pathophysiology of diabetes mellitus (DM) following acute pancreatitis (AP).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/02/2024
Locations: University of Southern California, Los Angeles, California +1 locations
Conditions: Acute Pancreatitis
Register for Updates
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease
NCT02852031
Recruiting
The purpose of this initiative is to improve care and outcomes for infants with HLHS by expanding the NPC-QIC national registry to gather clinical care process, outcome, and developmental data on infants with HLHS between diagnosis and 12 months of age, by improving the use of standards into everyday practice across pediatric cardiology centers, and by engaging parents as partners in the process.
Gender:
ALL
Ages:
15 months and below
Trial Updated:
05/01/2024
Locations: Children's Hospital Los Angeles, Los Angeles, California +1 locations
Conditions: Hypoplastic Left Heart Syndrome (HLHS)
Register for Updates