There are currently 2033 clinical trials in Los Angeles, California looking for participants to engage in research studies. Trials are conducted at various facilities, including Cedars-Sinai Medical Center, USC Norris Comprehensive Cancer Center, Children's Hospital Los Angeles and University of California Los Angeles. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
CAN-Stim Compared to SNS in Treatment of Urinary Urgency Incontinence With Wireless Neuromodulation Technology
NCT02577302
Recruiting
This is a prospective, randomized, controlled, multi-center, study in which 150 evaluable subjects will be randomized 1:1 to receive either a Protect CAN-Stim or SNS InterStim® system. Subjects from both groups will immediately start with therapy. The primary endpoint is a ≥ 50% reduction in number of incontinence episodes associated with urgency at the 3-month visit, with additional measurements assessed at 14 days, 1, 6, 9 and 12-months.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/03/2023
Locations: Kaiser Permanente, Los Angeles, California
Conditions: Urinary Incontinence, Urge
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Spine Procedures Assisted With RoboTics And Navigation
NCT05071144
Recruiting
Creation of a pediatric robotic spine surgery registry will allow for data collection and analysis on the coupled use of robotics and navigation in pediatric spine deformity surgery across participating study institutions. Eventually, an educational and informative framework for this technology will be established.
Gender:
All
Ages:
Between 0 years and 21 years
Trial Updated:
10/03/2023
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Spine Deformity, Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis, Spondylolisthesis, Congenital Scoliosis, Neuromuscular Scoliosis
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Transcutaneous Electrical Acupoint Stimulation (TEAS) for Chronic Constipation
NCT03243955
Recruiting
Transcutaneous electrical acupoint stimulation (TEAS) is an emerging technology for non-invasive neuromodulation that has broad potential implications and warrants further study. The investigators' clinical experience from the University of California, Los Angeles (UCLA) Center for East-West Medicine (CEWM) has also demonstrated that TEAS can be used as an effective self-care tool for patients with chronic illness who do not have the time or resources for frequent acupuncture treatments. Chronic... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/02/2023
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Constipation - Functional
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SAMe Trial for Patients With Alcoholic Cirrhosis
NCT04250259
Recruiting
The proposed of this randomized, double blinded, placebo-controlled study is to assess the effect of SAMe compared to placebo in patients with alcoholic cirrhosis Child Class A and B. The primary objective of the study is to test relationship between SAMe (S-adenosylmethionine) supplement on liver function. The hypothesis is that SAMe supplement will improve liver function in patients with alcoholic liver disease. The improvement in liver function will lead to the reduction in all-cause mortalit... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
10/02/2023
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Alcoholic Cirrhosis
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Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone
NCT03295981
Recruiting
The purpose of the clinical study is to investigate whether the local delivery of bisphosphonate as a surgical adjuvant can decrease the chance of a giant cell tumor of bone coming back to the same location. The hypothesis is that the local administration of bisphosphonate will decrease the rate of the tumor returning compared to traditional aggressive surgical removal of the tumor.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/02/2023
Locations: University of California - Los Angeles, Los Angeles, California
Conditions: Giant Cell Tumor of Bone
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A Single-arm, Multicenter Study to Assess the Efficacy, Safety, and Tolerability of P1101 in Adults With ET
NCT05482971
Recruiting
A Single-arm, Multicenter Study to Assess the Efficacy, Safety, and Tolerability of Ropeginterferon alfa-2b-njft (P1101) in Adult Patients with Essential Thrombocythemia
Gender:
All
Ages:
18 years and above
Trial Updated:
10/01/2023
Locations: USC Norris Comprehensive Cancer Center, Los Angeles, California
Conditions: Essential Thrombocythemia
Register for Updates
Impact of Sinus Surgery on Individuals With Cystic Fibrosis
NCT04469439
Recruiting
This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of life, and others.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
09/29/2023
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Chronic Rhinosinusitis (Diagnosis), Cystic Fibrosis
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Decoding and Selective Modulation of Human Memory During Awake/Sleep Cycles
NCT05452122
Recruiting
The proposed project seeks to elucidate memory processes and consolidation during sleep by leveraging the unique capability of direct recordings from the human brain at multiple levels of resolution-single neurons, localized neuronal assemblies, intracranial local field potentials-during rich behavioral tasks with real-life narratives and extracting neural features that relate to different aspects of episodic experience. The investigators will further probe causal mechanisms of consolidation by... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
09/29/2023
Locations: University of California Los Angeles, Los Angeles, California
Conditions: Memory, Delayed
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A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Huntington's Disease
NCT05655520
Recruiting
The primary purpose of the study is to evaluate the safety and tolerability of SAGE-718 softgel lipid capsule in participants with Huntington's Disease (HD)
Gender:
All
Ages:
Between 25 years and 65 years
Trial Updated:
09/29/2023
Locations: Sage Investigational Site, Los Angeles, California
Conditions: Huntington Disease
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Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty
NCT04717869
Recruiting
Frailty, the decline in physical and cognitive reserves leading to vulnerability to stressors is increasingly being recognized as a public health concern. Although multiple measures exist that can identify frail patients, very little is known about how or when to intervene. Sarcopenia, or the degree of muscle wasting, is closely correlated to frailty and patient outcomes. This is a prospective cohort study of critically ill patients to identify modifiable risk factors of sarcopenia, as potential... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/27/2023
Locations: Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine, Los Angeles, California
Conditions: Frailty, Sarcopenia
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A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
NCT05271604
Recruiting
This is a multi-center, open-label Phase 2 study designed to evaluate the efficacy and safety of BA3021 in PD-1/L1 failure patients with ROR-2 expression in recurrent or metastatic squamous cell carcinoma of the head and neck.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/27/2023
Locations: USC Norris Comprehensive Cancer Center, Los Angeles, California
Conditions: Head and Neck Cancer, Squamous Cell Carcinoma of Head and Neck, Recurrent Squamous Cell Carcinoma of the Head and Neck, Metastatic Cancer, Metastatic Squamous Cell Carcinoma of the Head and Neck
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Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma
NCT05045027
Recruiting
This clinical trial constructs and tests a novel multinuclear metabolic magnetic resonance imaging (MRI) sequence in patients with glioma (brain tumor) that is newly diagnosed or has come back (recurrent). This trial aims to develop new diagnostic imaging technology that may bridge gaps between early detection and diagnosis, prognosis, and treatment in brain cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/27/2023
Locations: UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California
Conditions: Glioma, Malignant Glioma, Recurrent Glioma, Recurrent Malignant Glioma
Register for Updates