There are currently 205 clinical trials in Newport Beach, California looking for participants to engage in research studies. Trials are conducted at various facilities, including Hoag Memorial Hospital Presbyterian, USC Norris Oncology/Hematology-Newport Beach, GSK Investigational Site and Eye Research Foundation. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Safety of AV-MEL-1 With Anti-PD-1 Therapy in Metastatic Melanoma
NCT03743298
Recruiting
This is an open label, single-arm, phase IB treatment study to determine the safety of administering anti-PD1 monoclonal antibodies with AV-MEL-1 and to get some suggestion of efficacy, in patients with measurable metastatic melanoma. The study is open to patients who have either never received treatment for metastatic melanoma or were previously treated with anti-PD-1 with or without anti-CTLA-4 or with enzymatic inhibitors of the BRAF/MEK pathway because of BRAF600E/K mutations, and are about... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/07/2023
Locations: Hoag Memorial Hospital Presbyterian, Newport Beach, California
Conditions: Metastatic Melanoma
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U01-Biomarkers for Noninvasive and Early Detection of Pancreatic Cancer
NCT03886571
Recruiting
This is an observational, biospecimen collection protocol to develop a bank of pancreatic cancer tissue and normal tissue.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2023
Locations: Hoag Memorial Hospital Presbyterian, Newport Beach, California
Conditions: Pancreatic Cancer
Register for Updates
Perioperative Mindfulness Proposal
NCT04049214
Recruiting
The purpose of this study is to determine if a regular meditation and breath work practice started before surgery and continued through post-surgical recovery can improve anxiety and pain related to breast cancer and its treatment.
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/27/2023
Locations: Hoag Memorial Hospital Presbyterian, Newport Beach, California
Conditions: Breast Cancer, DCIS
Register for Updates
A Retrospective Trial to Evaluate the Micra Pacemaker
NCT04051814
Recruiting
This is a retrospective study of our patient population implanted with the Medtronic's Leadless single-chamber ventricular pacemakers.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2023
Locations: Hoag Memorial Hospital Presbyterian, Newport Beach, California
Conditions: Pacemaker
Register for Updates
Atrial Fibrillation Ablation Registry
NCT04055961
Recruiting
The Atrial Fibrillation Ablation Registry (AFib Ablation Registry™) is designed to assess the prevalence, demographics, management, and outcomes of patients undergoing percutaneous catheter ablation procedures to treat atrial fibrillation (AF).
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2023
Locations: Hoah Memorial Hospital Presbyterian, Newport Beach, California
Conditions: Atrial Fibrillation
Register for Updates
STS & ACC Foundation's Transcutaneous Valve Therapy (TVT) Registry Foundation's Transcutaneous Valve Therapy (TVT) Registry
NCT04167579
Recruiting
The TVT Registry was designed to support a national surveillance system to assess the characteristics, treatments, and outcomes of patients receiving transcutaneous valve therapies.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2023
Locations: Hoah Memorial Hospital Presbyterian, Newport Beach, California
Conditions: Transcutaneous Valve Therapies
Register for Updates
AMDX-2011P Retinal Tracer in Subjects With Neurodegenerative Diseases Associated With Amyloidogenic Proteinopathy
NCT05542576
Recruiting
The purpose of this research study is to assess safety and tolerability of a single intravenous (given through a vein) dose of the investigational retinal tracer AMDX-2011P in patients with neurodegenerative diseases (Parkinson's disease and ALS).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/31/2023
Locations: Eye Research Foundation, Newport Beach, California
Conditions: Parkinson Disease, Amyotrophic Lateral Sclerosis
Register for Updates
A Study of ZN-c3 in Participants With Solid Tumors
NCT04158336
Recruiting
This is a Phase 1 open-label, multicenter study of ZN-c3 monotherapy which consists of Dose Escalation, a Food Effect Cohort, and Dose Expansion.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2023
Locations: Site 0167, Newport Beach, California
Conditions: Solid Tumor
Register for Updates
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
NCT05401357
Recruiting
This is a randomized, double-blind, two-treatment, single-period, parallel design, multiple dose at multiple clinical trial sites designed to demonstrate bioequivalence with clinical endpoint in subjects with chronic open-angle glaucoma or ocular hypertension in both eyes. Test Product - Bimatoprost ophthalmic solution, 0.01% of Amneal EU, Limited Reference Product - LUMIGAN® (bimatoprost ophthalmic solution) 0.01% of Allergan, Inc.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/09/2022
Locations: Eye Research Foundation Inc., Newport Beach, California
Conditions: Glaucoma, Open-Angle, Ocular Hypertension
Register for Updates
PET MRI as a Staging Tool for Head and Neck Cancer
NCT04750434
Recruiting
To explore the use of PET/MRI in the staging and pretreatment evaluation of patients with head and neck cancer and to compare this modality to standard PET/CT imaging.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/01/2022
Locations: Hoag Memorial Hospital Presbyterian, Newport Beach, California
Conditions: Head Cancer, Neck Cancer
Register for Updates
A Phase 3, Multi-Center Study Evaluating PL9643 in Patients With Dry Eye
NCT05201170
Recruiting
This is a multi-center, double-masked, randomized, vehicle-controlled study testing PL9643, an opthalmic solution to determine if safe and efficacious for dry eye patients. After a 2-week run-in period, patients will be randomized equally to the PL9643 opthalmic solution or vehicle opthalmic solution administered bilaterally three times a day for 12 weeks. A Data Monitoring Committee will be engaged to review interim data.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/08/2022
Locations: Palatin Clinical Site #9, Newport Beach, California
Conditions: Dry Eye, Dry Eye Syndromes
Register for Updates
Duration of Botox Using OLD Versus COLD for Treatment of Glabellar Lines
NCT05083286
Recruiting
This is a blinded, randomized study in the US to compare the duration response of two different concentrations of BOTOX in healthy female subjects with moderate to severe dynamic glabellar lines on maximum frown.
Gender:
Female
Ages:
18 years and above
Trial Updated:
10/20/2021
Locations: Steve Yoelin MD, Newport Beach, California
Conditions: Glabellar Frown Lines
Register for Updates