There are currently 199 clinical trials in Newport Beach, California looking for participants to engage in research studies. Trials are conducted at various facilities, including Hoag Memorial Hospital Presbyterian, USC Norris Oncology/Hematology-Newport Beach, GSK Investigational Site and Eye Research Foundation. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
AMDX-2011P Retinal Tracer in Subjects With Neurodegenerative Diseases Associated With Amyloidogenic Proteinopathy
Recruiting
The purpose of this research study is to assess safety and tolerability of a single intravenous (given through a vein) dose of the investigational retinal tracer AMDX-2011P in patients with neurodegenerative diseases (Parkinson's disease and ALS).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/31/2023
Locations: Eye Research Foundation, Newport Beach, California
Conditions: Parkinson Disease, Amyotrophic Lateral Sclerosis
A Study of ZN-c3 in Participants With Solid Tumors
Recruiting
This is a Phase 1 open-label, multicenter study of ZN-c3 monotherapy which consists of Dose Escalation, a Food Effect Cohort, and Dose Expansion.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2023
Locations: Site 0167, Newport Beach, California
Conditions: Solid Tumor
Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGANĀ® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
Recruiting
This is a randomized, double-blind, two-treatment, single-period, parallel design, multiple dose at multiple clinical trial sites designed to demonstrate bioequivalence with clinical endpoint in subjects with chronic open-angle glaucoma or ocular hypertension in both eyes. Test Product - Bimatoprost ophthalmic solution, 0.01% of Amneal EU, Limited Reference Product - LUMIGANĀ® (bimatoprost ophthalmic solution) 0.01% of Allergan, Inc.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/09/2022
Locations: Eye Research Foundation Inc., Newport Beach, California
Conditions: Glaucoma, Open-Angle, Ocular Hypertension
PET MRI as a Staging Tool for Head and Neck Cancer
Recruiting
To explore the use of PET/MRI in the staging and pretreatment evaluation of patients with head and neck cancer and to compare this modality to standard PET/CT imaging.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/01/2022
Locations: Hoag Memorial Hospital Presbyterian, Newport Beach, California
Conditions: Head Cancer, Neck Cancer
A Phase 3, Multi-Center Study Evaluating PL9643 in Patients With Dry Eye
Recruiting
This is a multi-center, double-masked, randomized, vehicle-controlled study testing PL9643, an opthalmic solution to determine if safe and efficacious for dry eye patients. After a 2-week run-in period, patients will be randomized equally to the PL9643 opthalmic solution or vehicle opthalmic solution administered bilaterally three times a day for 12 weeks. A Data Monitoring Committee will be engaged to review interim data.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/08/2022
Locations: Palatin Clinical Site #9, Newport Beach, California
Conditions: Dry Eye, Dry Eye Syndromes
Duration of Botox Using OLD Versus COLD for Treatment of Glabellar Lines
Recruiting
This is a blinded, randomized study in the US to compare the duration response of two different concentrations of BOTOX in healthy female subjects with moderate to severe dynamic glabellar lines on maximum frown.
Gender:
Female
Ages:
18 years and above
Trial Updated:
10/20/2021
Locations: Steve Yoelin MD, Newport Beach, California
Conditions: Glabellar Frown Lines
An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis
Recruiting
The present study D5272C00001 (Legacy # 3151-201-008) seeks to evaluate the efficacy and safety of brazikumab versus placebo in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
01/19/2021
Locations: Research Site, Newport Beach, California
Conditions: Ulcerative Colitis