There are currently 23 active clinical trials seeking participants for Atherosclerosis research studies. The states with the highest number of trials for Autism participants are California, Florida, Texas and New York.
Stroke Prevention in the Wisconsin Native American Population
NCT04382963
Recruiting
This project will develop a "Stroke Awareness Team" including training of Oneida Health Service Coaches working in partnership with the UW team for a population-based health awareness program. This team will develop a series of Oneida Nation Healthy Living and Stroke Awareness Events (from now on health events) to provide education as to the severity of the problem as well as our standard therapies for lifestyle change and risk factor avoidance. This will include education of the healthy members... Read More
Gender:
All
Ages:
Between 55 years and 80 years
Trial Updated:
11/22/2023
Locations: University of Wisconsin-Madison, Madison, Wisconsin +1 locations
Conditions: Stroke, Atherosclerosis
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Advancing Postmenopausal Preventive Therapy
NCT04103476
Recruiting
Advancing Postmenopausal Preventive Therapy (APPT) is a randomized, double-blinded, placebo-controlled trial designed to determine the effects of tissue selective estrogen complex (TSEC) therapy on the progression of subclinical atherosclerosis and cognitive decline in 360 healthy postmenopausal women.
Gender:
Female
Ages:
Between 45 years and 59 years
Trial Updated:
11/21/2023
Locations: University of Southern California Atherosclerosis Research Unit, Los Angeles, California
Conditions: Atherosclerosis, Cognitive Decline
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Massachusetts General Hospital and Tsuchiura Kyodo General Hospital Coronary Imaging Collaboration
NCT04523194
Recruiting
The purpose of this collaboration is to establish a multi-modality image database including coronary angiograms, optical coherence tomography (OCT), computed tomography angiograms (CTA) and cardiac magnetic resonance imaging (CMR) for future studies. The main goal of this collaboration is to create a resource to promote further understanding of the pathobiology of atherosclerosis through image analysis.
Gender:
All
Ages:
All
Trial Updated:
10/19/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations
Conditions: Atherosclerosis
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Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History
NCT05867381
Recruiting
This double-blind, randomized, crossover trial aims to test the hypothesis that longer-term indoor air filtration intervention can slow atherothrombosis progression by reducing indoor fine particulate matter (PM2.5) exposure in adults with ischemic heart disease history.
Gender:
All
Ages:
Between 65 years and 84 years
Trial Updated:
09/22/2023
Locations: Keck School of Medicine, University of Southern California, Los Angeles, California
Conditions: Air Pollution, Atherosclerosis
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IMPact on Revascularization Outcomes of IVUS Guided Treatment of Complex Lesions and Economic Impact
NCT04221815
Recruiting
Intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) has been shown in clinical trials, registries, and meta-analyses to reduce recurrent events after PCI. This is accomplished by improving the angiographic result with lesion and vessel assessment to guide stent selection and implantation and intravascular imaging following stent implantation to ensure an adequate treatment endpoint has been achieved. Despite extensive literature supporting the use of IVUS in PCI, util... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/21/2023
Locations: Northwest Medical Center, Tucson, Arizona +46 locations
Conditions: Atherosclerosis
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PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]
NCT05994014
Recruiting
Early detection of coronary atherosclerotic disease facilitates adequate prevention. The purpose of this study is to compare an assessment of coronary atherosclerotic disease burden by positron emission tomography / computed tomography (NaF-PET/CT) with those of conventional and ultra-high-resolution-CT (UHR-CT) in patients with suspected coronary artery disease. For this purpose, the investigators plan to include 33 patients with symptoms concerning for CAD who have been referred for cardiac CT... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/08/2023
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Coronary Artery Disease, Atherosclerosis, Coronary Atherosclerosis of Native Coronary Artery
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Comparing Perclose to Statseal in Conjunction With Perclose in Femoral 6 French Arteriotomy Closure
NCT05468957
Recruiting
The purpose of this clinical study is to compare how well two different devices for achieving hemostasis perform in patients undergoing transfemoral procedures with 6 French Access. Both devices are approved by the FDA for this use, and have already been used by clinicians on patients undergoing transfemoral procedures. It is believed that the use of both devices in combination compared to the Perclose alone will shorten the time that it takes to 'seal' the artery, resulting in a shorter period... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/28/2023
Locations: UCLA Ronald Reagen, Los Angeles, California +1 locations
Conditions: Arterial Occlusion, Cardiovascular Diseases, Atherosclerosis, Hematoma
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Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)
NCT05488431
Recruiting
This is a randomized placebo-controlled study in treated and suppressed HIV-infected individuals aged ≥40 years with either known CVD or 1 CVD risk factor to study the effect of Bempedoic acid (BA) on safety, arterial inflammation as assessed by FDG-PET/CT, lipids, inflammation, immune activation, cardiometabolic indices, and non-calcified plaque (NCP) in the coronary arteries (assessed by coronary CT angiography, CCTA). This trial will be enrolled at UCSF and UCLA. Collaborators at Massachusett... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
06/28/2023
Locations: San Francisco General Hospital, San Francisco, California
Conditions: Dyslipidemias, Cardiovascular Diseases, HIV Infections, Atherosclerosis
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Text Education About Cardiovascular Health and HIV (TEACH-HIV)
NCT05642858
Recruiting
The overall objective is to evaluate the efficacy of educational text messages to reduce cardiovascular risk among persons living with HIV (PLWH).
Gender:
All
Ages:
40 years and above
Trial Updated:
03/10/2023
Locations: Zuckerberg San Francisco General Hospital, San Francisco, California +1 locations
Conditions: HIV, Human Immunodeficiency Virus, Cardiovascular Diseases, Atherosclerosis
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The Role of microRNA-210 in Regulating Oxidative Stress in Patients With PAD
NCT04089943
Recruiting
MicroRNA-210 (miR-210) can be a potential therapeutic target of patients with peripheral artery disease (PAD). Recent evidence suggests the role of miR-210 and oxidative stress in the pathophysiology of PAD and its association with mitochondrial function, oxidative metabolism, walking distances and quality of life. The protocol evaluates the mechanisms which miR-210 regulates oxidative stress and provides evidence of potential therapeutic strategies.
Gender:
All
Ages:
30 years and above
Trial Updated:
02/03/2023
Locations: University of Texas Health Science Center at San Antonio, San Antonio, Texas +1 locations
Conditions: Peripheral Arterial Disease, Vascular Diseases, Peripheral, Arterial Occlusive Diseases, Atherosclerosis
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Pilot Study-Magnetic Resonance Imaging for Global Atherosclerosis Risk Assessment
NCT02265250
Recruiting
Cardiovascular disease (CVD) remains the leading cause of death in the United States, and improved CVD risk assessment is needed for personalized medicine. Atherosclerosis measures including plaque volume and adverse plaque features have prognostic value. Novel techniques have been developed for assessing carotid, coronary, and femoral atherosclerosis using magnetic resonance imaging (MRI) methods that are rapid and reproducible, have improved spatial resolution, and do not require contrast medi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/06/2020
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Cardiovascular Disease, Atherosclerosis
Register for Updates