There are currently 43 active clinical trials seeking participants for Brain Tumor research studies. The states with the highest number of trials for Brain Tumor participants are California, Florida, New York and Texas.
Cognitive Training in the Virtual Reality Setting With Children Undergoing Radiotherapy for Brain Tumors
NCT05947045
Recruiting
The objective of this study is to estimate the feasibility and acceptability of cognitive training in the virtual reality setting with children undergoing radiotherapy for brain tumors. To achieve this goal, the investigators plan to study children undergoing radiotherapy for brain tumors randomly assigned to cognitive training administered via an iPad or virtual reality. Both groups will also participate in cognitive testing and exams using functional near infrared spectroscopy (fNIRS) pre- and... Read More
Gender:
ALL
Ages:
Between 8 years and 22 years
Trial Updated:
08/13/2024
Locations: St. Jude Children's Research Hospital, Memphis, Tennessee
Conditions: Brain Tumor
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The Neural Code and Dynamics of the Reading Network.
NCT05989893
Recruiting
The purpose of this study is to compare organization of normal brain function as detected using Functional magnetic resonance imaging (fMRI) in normal subjects as opposed to patients with epilepsy or brain tumors, to ascribe precise anatomic labels (including Brodmann Areas) and functional significance to each region involved in cognitive processes as detected by cortical stimulation mapping (CSM) in patients with implanted subdural electrodes (SDE) or depth (sEEG) electrodes, to describe the lo... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
06/27/2024
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Epilepsy, Brain Tumor
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A Study of How Proton Beam Radiotherapy (PBRT) Affects Brain Function and Quality of Life in Children and Young Adults Undergoing Treatment for a Brain Tumor
NCT05288439
Recruiting
The researchers are doing this study to find out if there are differences in the resting state brain networks of children and young adults (ages 6-25) after treatment with proton beam radiation therapy (PBRT). The researchers will use resting state functional connectivity magnetic resonance imagining (rs-fcMRI) scanning to detect these differences. The researchers will also check for differences in participants' thinking and quality of life through a cognitive assessment and a questionnaire. Bot... Read More
Gender:
All
Ages:
Between 6 years and 25 years
Trial Updated:
06/07/2024
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Brain Tumor, Metastatic Brain Tumor
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Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients
NCT05658731
Recruiting
The goal of this trial is to determine whether it is possible to minimize radiation dose to parts of the brain that are important for thinking and learning in children who require radiation to treat their tumor, and if this will help reduce neurocognitive (thinking and learning) impairments in these patients. Patients with newly diagnosed brain or head and neck tumors who are having radiation therapy will have neurocognitive testing and MRI imaging (both research and for regular care) done as p... Read More
Gender:
All
Ages:
Between 1 year and 26 years
Trial Updated:
06/05/2024
Locations: Sibley Memorial Hospital, Washington, District of Columbia +1 locations
Conditions: Brain Tumor, Head and Neck Cancer
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European Prospective Investigation Into Childhood Cancer
NCT05375617
Recruiting
Over the last decades, research has shown that poor nutritional status can adversely impact prognosis and increase toxicities during treatment for childhood cancer. EPICkids is a collaboration between the International Initiative for Pediatrics and Nutrition, the International Agency for Research on Cancer, and sites throughout three Southern European countries (Spain, Greece, and Italy). The primary aim of EPICkids is to establish an informational resource on critical nutrition parameters where... Read More
Gender:
All
Ages:
Between 3 years and 21 years
Trial Updated:
05/28/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Acute Lymphoblastic Leukemia, Brain Tumor
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APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
NCT03175224
Recruiting
To assess: efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET amplification, solid tumors harboring MET fusion, primary CNS tumors harboring MET alterations, solid tumors harboring wild-type MET with overexpression of HGF and MET efficacy of APL-101 as an add-on therapy to EGFR inhibitor for the treatment of NSCLC harboring EGFR activating mutations and developed acquired resistanc... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2024
Locations: Loma Linda University Medical Center, Loma Linda, California +90 locations
Conditions: Advanced Cancer, Renal Cancer, Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, NSCLC, Lung Cancer, Brain Tumor, Glioblastoma Multiforme, Solid Tumors, EGFR Gene Mutation, MET Amplification, HGF, Thyroid Cancer, Pancreatic Cancer, Colon Cancer, MET Alteration, MET Fusion, Exon 14 Skipping
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Systematic Light Exposure in Pediatric Brain Tumor Survivors
NCT05340881
Recruiting
Children and adolescents treated for a brain tumor often experience fatigue and cognitive symptoms, such as slowed information processing and inattention. These symptoms may cause difficulty carrying out daily activities at home and at school. There are few well-researched, non-pharmacological interventions aimed at improving symptoms of fatigue and by extension cognitive symptoms. Systematic bright light exposure has been shown to improve symptoms of fatigue in adult survivors of cancer and chi... Read More
Gender:
All
Ages:
Between 10 years and 18 years
Trial Updated:
04/10/2024
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Brain Tumor
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Extracellular Impact of Ultrasound-induced Blood-brain Barrier Disruption
NCT05733312
Recruiting
This study seeks to determine the impact of focused ultrasound (FUS) on the composition of the tumor extracellular microenvironment. Researchers will evaluate regions that are very abnormal, as well as regions that have less evidence of disease. A sub-portion of each of these areas will be targeted by focused ultrasound. Microdialysis catheters will then be placd into each region that has and has not been exposed to FUS (total of 4 catheters) to determine how FUS impacts the the brain and tumor... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/09/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Brain Tumor
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Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy
NCT03286335
Recruiting
This research study is studying Proton Radiation as a possible treatment for brain tumor. The radiation involved in this study is: -Proton Radiation
Gender:
All
Ages:
18 years and above
Trial Updated:
03/25/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Brain Tumor
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A Trial of Increased Dose Intensity Modulated Proton Therapy (IMPT) for High-Grade Meningiomas
NCT02693990
Recruiting
This research study is studying radiation therapy as a possible treatment for meningioma or tumor on the lining of the brain. The study drug or intervention involved in this research study is Intensity Modulated Proton Therapy (IMPT)
Gender:
All
Ages:
18 years and above
Trial Updated:
03/22/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations
Conditions: Meningioma, Brain Tumor
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Blood-brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets
NCT05317858
Recruiting
The purpose of this study is to evaluate the safety and efficacy of targeted blood brain barrier disruption with Exablate Model 4000 Type 2.0/2.1 for the treatment of NSCLC brain metastases in patients who are undergoing planned pembrolizumab monotherapy.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
03/12/2024
Locations: St. Joseph's Hospital and Medical Center, Phoenix, Arizona +7 locations
Conditions: Brain Tumor
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Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma
NCT02861898
Recruiting
Primary brain cancer kills up to 10,000 Americans a year. These brain tumors are typically treated by surgery, radiation therapy and chemotherapy, either individually or in combination. Present therapies are inadequate, as evidenced by the low 5-year survival rate for brain cancer patients, with median survival at approximately 12 months. Glioma is the most common form of primary brain cancer, afflicting approximately 7,000 patients in the United States each year. These highly malignant cancers... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/23/2024
Locations: Lenox Hill Brain Tumor Center, New York, New York
Conditions: Glioblastoma, Brain Cancer, Brain Neoplasm, Brain Tumor, Brain Neoplasm, Malignant, EGFR Gene Overexpression, GBM
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