There are currently 17 active clinical trials seeking participants for Depressive Disorder, Major research studies. The states with the highest number of trials for Depressive Disorder, Major participants are California, Florida, Texas and New York.
InMotion - Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI
Recruiting
The purpose of this randomized controlled trial is to evaluate whether the InMotion intervention, delivered via telehealth (using a HIPAA-compliant video platform or phone), which uses evidence-based behavioral and motivational counseling to increase daily physical activity, is an effective treatment for Major Depressive Disorder (MDD) for people who are at least one year out from sustaining a traumatic brain injury (TBI). The first aim is to compare the efficacy of the InMotion intervention to... Read More
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
11/27/2023
Locations: University of Washington Medical Center, Seattle, Washington
Conditions: TBI (Traumatic Brain Injury), Depressive Disorder, Major, Clinical Depression, Mood Depressed, Physical Inactivity
Biomarkers of Depression and Treatment Response
Recruiting
This study is a stratified, parallel-group, single-center study utilizing multimodal imaging techniques to identify biomarkers for Major Depressive Disorder (MDD). The study goal is to identify biomarkers for MDD and treatment response that can be implemented in clinical diagnosis and care as valid and reliable measures, through monitoring neurophysiological and electrophysiological changes across the course of transcranial magnetic stimulation (TMS) treatment.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
11/16/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Depressive Disorder, Major
Rapid Acting TMS for Suicide Ideation in Depression
Recruiting
This study evaluates the effects of an accelerated schedule of theta-burst stimulation, termed accelerated intermittent theta-burst stimulation (aiTBS), on the neural networks underlying explicit and implicit suicidal cognition in inpatients with major depressive disorder.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
11/08/2023
Locations: Stanford Hospital, Stanford, California
Conditions: Depressive Disorder, Major, Suicide
Treatment of Acute Mood Depressive Episode in Borderline Personality Disorder With rTMS
Recruiting
This study evaluates the antidepressant effects of an accelerated schedule of theta-burst stimulation, termed accelerated intermittent theta-burst stimulation (aiTBS), in individuals with borderline personality disorder (BPD) or trait and comorbid mood depressive disorder (MDD) or bipolar II disorder in a current mood depressive episode (MDE).
Gender:
All
Ages:
Between 22 years and 65 years
Trial Updated:
07/17/2023
Locations: Stanford Hospital, Stanford, California
Conditions: Depressive Disorder, Major, Borderline Personality Disorder
Cognitive Fitness for Depression in Older Adults
Recruiting
This research is being done to determine if computerized administered cognitive fitness activities will improve thinking and depression in older depressed adults who are being treated with antidepressants. The investigators are also interested in whether participating in the treatment will result in changes to brain activity measured with magnetic resonance imaging (MRI).
Gender:
All
Ages:
60 years and above
Trial Updated:
11/02/2022
Locations: UConn Health, Farmington, Connecticut
Conditions: Depression Mild, Depressive Disorder, Major, Mild Cognitive Impairment