There are currently 14 active clinical trials seeking participants for Depressive Disorder, Major research studies. The states with the highest number of trials for Depressive Disorder, Major participants are California, Florida, Texas and New York.
Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression
Recruiting
In this project, we use real-time fMRI neurofeedback (rtfMRI-nf) to causally relate dysfunction of right anterior insula (rAI) and right superior temporal sulcus (rSTS) connectivity with the intensity of repetitive negative thinking (RNT). We hypothesize that rtfMRI-nf reducing rAI-rSTS connectivity would reduce RNT. We propose a randomized double-blind, sham-controlled trial of rtfMRI-nf with 110 young adults (n=55/arm) with major depressive disorder (MDD) and high trait-RNT levels.
Gender:
All
Ages:
Between 18 years and 35 years
Trial Updated:
01/12/2024
Locations: Laureate Institute for Brain Research, Tulsa, Oklahoma
Conditions: Depressive Disorder, Major
Biomarkers of Depression and Treatment Response
Recruiting
This study is a stratified, parallel-group, single-center study utilizing multimodal imaging techniques to identify biomarkers for Major Depressive Disorder (MDD). The study goal is to identify biomarkers for MDD and treatment response that can be implemented in clinical diagnosis and care as valid and reliable measures, through monitoring neurophysiological and electrophysiological changes across the course of transcranial magnetic stimulation (TMS) treatment.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
11/16/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Depressive Disorder, Major