Diffuse Large B-Cell Lymphoma Clinical Trials

A listing of 33 Diffuse Large B-Cell Lymphoma clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

Home

All Conditions

Diffuse Large B-Cell Lymphoma

13 - 24 of 33

Show Filters

Match to Clinical Trials

Access to cutting-edge treatments

Latest clinical trials

Find trials in your area

Start Matching

Filter by Age

There are currently 33 active clinical trials seeking participants for Diffuse Large B-Cell Lymphoma research studies. The states with the highest number of trials for Autism participants are Ohio, California, New York and Other.

Featured Trial

Major Depressive Disorder Clinical Study

Recruiting

Is depression weighing you down? Local major depressive disorder clinical studies are now enrolling participants in the area. Participating in research studies helps contribute to the advancement of future medicine and treatment options. There is no obligation to take part and health insurance is not required.

Conditions:

Major Depressive Disorder

Major Depression

Major Depressive Episode

Major Depressive Disorder (MDD)

Major Depressive Disorders

Learn More

Featured Trial

Hyperacusis Activities Treatment-Online Study

Recruiting

Are you experiencing hyperacusis? If so, we are recruiting adults with hyperacusis to complete a clinical trial supported by the National Institutes of Health. The study involves participating in a remote counseling program and sound therapy trial for hyperacusis, Hyperacusis Activities Treatment-Online.

Conditions:

Hyperacusis

Tinnitus

Hearing Loss

Learn More

Rituximab, Lenalidomide, Acalabrutinib, Tafasitamab Alone and With Combination Chemotherapy for the Treatment of Newly Diagnosed Non-germinal Center Diffuse Large B-Cell Lymphoma, Smart Stop Study

NCT04978584

Recruiting

This phase II trial studies the effect of rituximab, lenalidomide, acalabrutinib, tafasitamab alone and in combination with chemotherapy in treating patients with newly diagnosed non-germinal center diffuse large B-cell lymphoma. Rituximab and tafasitamab are monoclonal antibodies that may interfere with the ability of tumor cells to grow and spread. Acalabrutinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide,... Read More

Gender:

All

Ages:

18 years and above

Trial Updated:

04/11/2024

Locations: M D Anderson Cancer Center, Houston, Texas

Conditions: Diffuse Large B-Cell Lymphoma

Learn More ›

A Study to Evaluate Adverse Events of Subcutaneous (SC) Epcoritamab Administered in the Outpatient Setting in Adult Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma and Classic Follicular Lymphoma

NCT05451810

Recruiting

B-cell Lymphoma is an aggressive and rare cancer of a type of immune cells (a white blood cell responsible for fighting infections). Classic Follicular Lymphoma is a slow-growing type of non-Hodgkin lymphoma. The purpose of this study is to assess the safety of epcoritamab in adult participants in relapsed or refractory (R/R) diffuse large b-cell lymphoma (DLBCL) who have received at least 1 prior line of systemic antilymphoma therapy including at least 1 anti-CD20 monoclonal antibody-containing... Read More

Gender:

All

Ages:

18 years and above

Trial Updated:

04/08/2024

Locations: University of Arkansas for Medical Sciences /ID# 244562, Little Rock, Arkansas +49 locations

University of Arkansas for Medical Sciences /ID# 244562, Little Rock, Arkansas

Compassionate Cancer Care Research Group - Fountain Valley /ID# 246133, Fountain Valley, California

University of California, Los Angeles /ID# 244573, Los Angeles, California

Rocky Mountain Cancer Centers /ID# 247653, Boulder, Colorado

Bennett Cancer Center - Stamford Hospital /ID# 244530, Stamford, Connecticut

Mount Sinai Medical Center-Miami Beach /ID# 249045, Miami Beach, Florida

Memorial Cancer Institute (MCI) - Memorial Hospital West /ID# 248432, Pembroke Pines, Florida

Cleveland Clinic Florida /ID# 244532, Weston, Florida

University of Illinois at Chicago /ID# 245038, Chicago, Illinois

Illinois Cancer Specialists /ID# 247655, Niles, Illinois

Parkview Cancer Institute /ID# 244545, Fort Wayne, Indiana

Indiana Blood & Marrow Transpl /ID# 244971, Indianapolis, Indiana

Mission Cancer and Blood /ID# 258227, Des Moines, Iowa

Our Lady of the Lake Regional Medical Center /ID# 255008, Baton Rouge, Louisiana

American Oncology Partners of Maryland, PA /ID# 244968, Bethesda, Maryland

Maryland Oncology Hematology /ID# 254192, Columbia, Maryland

Tufts Medical Center /ID# 246074, Boston, Massachusetts

Massachusetts General Hospital /ID# 245239, Boston, Massachusetts

Beth Israel Deaconess Medical Center /ID# 248651, Boston, Massachusetts

Cancer & Hematology Centers of Western Michigan - East /ID# 244985, Grand Rapids, Michigan

Trinity Health St. Joseph Mercy Ann Arbor /ID# 244547, Ypsilanti, Michigan

Hattiesburg Clinic /ID# 244980, Hattiesburg, Mississippi

St. Luke's Hospital - Chesterfield /ID# 247815, Chesterfield, Missouri

Dartmouth-Hitchcock Medical Center /ID# 245003, Lebanon, New Hampshire

Morristown Medical Center /ID# 244973, Morristown, New Jersey

University of New Mexico /ID# 252434, Albuquerque, New Mexico

Stony Brook University Medical Center /ID# 244631, New York, New York

New York Cancer and Blood Specialists /ID# 259016, Port Jefferson Station, New York

East Carolina University Brody School of Medicine /ID# 248989, Greenville, North Carolina

Wake Forest Univ HS /ID# 245005, Winston-Salem, North Carolina

Oncology Hematology Care, Inc. /ID# 246182, Cincinnati, Ohio

Toledo Clinic Cancer Center /ID# 246852, Toledo, Ohio

University of Oklahoma, Stephenson Cancer Center /ID# 244568, Oklahoma City, Oklahoma

Willamette Valley Cancer Institute and Research Center /ID# 246410, Eugene, Oregon

Oregon Oncology Specialists in Salem /ID# 260570, Salem, Oregon

Lehigh Valley Hospital-Cedar Crest /ID# 244984, Allentown, Pennsylvania

Penn State Milton S. Hershey Medical Center /ID# 244979, Hershey, Pennsylvania

UPMC Hillman Cancer Ctr /ID# 244571, Pittsburgh, Pennsylvania

Reading Hospital; McGlinn Cancer Institute /ID# 259181, West Reading, Pennsylvania

Prisma Health /ID# 247654, Greenville, South Carolina

The West Clinic /ID# 245004, Memphis, Tennessee

Texas Oncology - Austin Midtown /ID# 247656, Austin, Texas

University of Texas Southwestern Medical Center /ID# 244552, Dallas, Texas

Texas Oncology - San Antonio Medical Center /ID# 247658, San Antonio, Texas

Texas Oncology - Northeast Texas /ID# 247657, Tyler, Texas

Virginia Cancer Specialists - Gainesville /ID# 248760, Gainesville, Virginia

Blue Ridge Cancer Center /ID# 260597, Roanoke, Virginia

Northwest Medical Specialties - Tacoma /ID# 245045, Tacoma, Washington

Pan American Center for Oncology Trials, LLC /ID# 254952, Rio Piedras, Not set

Auxilio Mutuo Cancer Center /ID# 254953, San Juan, Not set

Conditions: Diffuse Large B-Cell Lymphoma, Classic Follicular Lymphoma

Learn More ›

A Study to Evaluate Change in Disease Activity of Subcutaneous (SC) Epcoritamab Combined With Intravenous and Oral Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone (R-CHOP) or R-CHOP in Adult Participants With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

NCT05578976

Recruiting

B-cell Lymphoma is an aggressive and rare cancer of a type of immune cells (a white blood cell responsible for fighting infections). The purpose of this study is to assess the change in disease activity of epcoritamab when combined with intravenous and oral rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine, and prednisone (R-CHOP) or R-CHOP in adult participants globally with diffuse large b-cell lymphoma (DLBCL). Change in disease activity will be assessed. Epcoritamab is an... Read More

Gender:

All

Ages:

Between 18 years and 79 years

Trial Updated:

04/08/2024

Locations: University of Arizona Cancer Center - North Campus /ID# 227463, Tucson, Arizona +262 locations

University of Arizona Cancer Center - North Campus /ID# 227463, Tucson, Arizona

University of Arkansas for Medical Sciences /ID# 225703, Little Rock, Arkansas

Orange Coast Memorial Medical Center /ID# 229632, Fountain Valley, California

Saddleback Memorial Medical Center /ID# 229631, Laguna Hills, California

Long Beach Memorial Medical Ct /ID# 228996, Long Beach, California

University of Southern California /ID# 225443, Los Angeles, California

University of California, Los Angeles /ID# 226887, Los Angeles, California

Orlando Health /ID# 232626, Orlando, Florida

Southern IL Univ School of Med /ID# 228999, Springfield, Illinois

Parkview Cancer Institute /ID# 227026, Fort Wayne, Indiana

Goshen Center for Cancer Care /ID# 225534, Goshen, Indiana

Mission Cancer and Blood /ID# 261945, Des Moines, Iowa

Norton Cancer Institute - St Matthews /ID# 225420, Louisville, Kentucky

American Oncology Partners of Maryland, PA /ID# 226859, Bethesda, Maryland

Trinity Health St. Joseph Mercy Ann Arbor /ID# 228206, Ypsilanti, Michigan

Metro Minnesota Community Oncology Research Consortium (MMCORC) /ID# 226680, Saint Louis Park, Minnesota

Intermountain Health - St Vincent Regional Hospital - Cancer Centers of Montana /ID# 259014, Billings, Montana

Titan Health Partners LLC, d/b/a Astera Cancer Care /ID# 226654, East Brunswick, New Jersey

Perlmutter Cancer Center at NYU Langone /ID# 262412, Mineola, New York

NYU Langone - Laura and Isaac Perlmutter Cancer Center /ID# 226141, New York, New York

Memorial Sloan Kettering Cancer Center-Koch Center /ID# 225379, New York, New York

University of Cincinnati /ID# 225374, Cincinnati, Ohio

Kaiser Permanente - Northwest /ID# 225488, Portland, Oregon

Millennium Research & Clinical Development /ID# 228284, Kingwood, Texas

University of Virginia Cancer Center - West Complex /ID# 225433, Charlottesville, Virginia

Vista Oncology - East Olympia /ID# 229375, Olympia, Washington

Multicare Institute for Research and Innovation /ID# 225432, Tacoma, Washington

Liverpool Hospital /ID# 230072, Liverpool, New South Wales

Royal Adelaide Hospital /ID# 225683, Adelaide, South Australia

Monash Medical Centre /ID# 225680, Clayton, Victoria

Austin Health /ID# 225716, Heidelberg, Victoria

Alfred Health /ID# 225999, Melbourne, Victoria

Hollywood Private Hospital /ID# 251837, Nedlands, Western Australia

Perth Blood Institute Ltd /ID# 225679, Nedlands, Western Australia

Royal Perth Hospital /ID# 226583, Perth, Western Australia

Universitaetsklinikum St. Poelten /ID# 234016, Sankt Poelten, Niederoesterreich

Medizinische Universitaet Wien /ID# 252095, Vienna, Wien

Klinik Ottakring /ID# 243941, Vienna, Wien

Landeskrankenhaus Salzburg-Universitaetsklinikum der PMU (LKH) /ID# 228360, Salzburg, Not set

UCL Saint-Luc /ID# 225737, Woluwe-Saint-Lambert, Bruxelles-Capitale

Hospital La Louviere Site Jolimont - Helora /ID# 225738, La Louvière, Hainaut

CHU de Liège /ID# 225952, Liège, Liege

CHU UCL Namur - site Godinne /ID# 225742, Godinne, Namur

UZ Gent /ID# 250031, Gent, Oost-Vlaanderen

Vitaz /Id# 226153, Sint-Niklaas, Oost-Vlaanderen

Universitair Ziekenhuis Leuven /ID# 225951, Leuven, Vlaams-Brabant

AZ-Delta /ID# 225736, Roeselare, West-Vlaanderen

Institut Jules Bordet /ID# 225954, Anderlecht, Not set

ZNA Middelheim /ID# 225741, Antwerp, Not set

AZ Sint-Jan Brugge /ID# 225735, Brugge, Not set

Hospital de Clinicas da Universidade Federal do Parana /ID# 226027, Curitiba, Parana

Hospital Amaral Carvalho - Fundacao Doutor Amaral Carvalho /ID# 226065, Jaú, Sao Paulo

Fundacao Antonio Prudente - AC Camargo Cancer Center /ID# 226809, São Paulo, Sao Paulo

Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein /ID# 252832, São Paulo, Sao Paulo

Real e Benemérita Associação Portuguesa de Beneficência /ID# 226023, Sao Paulo, Not set

Hospital Alemao Oswaldo Cruz /ID# 252833, Sao Paulo, Not set

Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao /ID# 226048, Sao Paulo, Not set

UMHAT Sveti Georgi /ID# 245780, Plovdiv, Not set

Acibadem City Clinic Tokuda University Hospital EAD /ID# 244616, Sofia, Not set

UMHAT Sveti Ivan Rilski /ID# 244615, Sofia, Not set

SHAT Hematologic Diseases /ID# 250102, Sofia, Not set

Tom Baker Cancer Centre /ID# 226077, Calgary, Alberta

BC Cancer - Vancouver /ID# 230573, Vancouver, British Columbia

William Osler Health System /ID# 250973, Brampton, Ontario

Saskatoon Cancer Centre /ID# 226082, Saskatoon, Saskatchewan

The Fifth Medical Center of PLA General Hospital /ID# 230941, Beijing, Beijing

Beijing Cancer Hospital /ID# 229819, Beijing, Beijing

Peking University Third Hospital /ID# 230975, Beijing, Beijing

Fujian Provincial Cancer Hospital /ID# 238430, Fuzhou, Fujian

Sun Yat-Sen University Cancer Center /ID# 238371, Guangzhou, Guangdong

Guangdong Provincial People's Hospital /ID# 230945, Guangzhou, Guangdong

Nanfang Hospital of Southern Medical University /ID# 238436, Guangzhou, Guangdong

Harbin Medical University Cancer Hospital /Id# 241755, Harbin, Heilongjiang

Union Hospital affiliated to Tongji Medical College of Huazhong University of Sc /ID# 234152, Wuhan, Hubei

Hubei Cancer Hospital /ID# 232256, Wuhan, Hubei

The First Affiliated Hospital of Soochow University /ID# 232569, Suzhou, Jiangsu

The Affiliated Hospital of Xuzhou Medical College /ID# 233174, Xuzhou, Jiangsu

The First Affiliated Hospital of Nanchang University /ID# 230399, Nanchang, Jiangxi

Jiangxi Provincial Cancer Hospital /ID# 233379, Nanchang, Jiangxi

The First Hospital of Jilin University /ID# 239618, Changchun, Jilin

The First Hospital of China Medical University /ID# 233201, Shenyang, Liaoning

Shandong Cancer Hospital /ID# 233200, Jinan, Shandong

Fudan University Cancer Hospital /ID# 251516, Shanghai, Shanghai

Tianjin Cancer Hospital /ID# 230974, Tianjin, Tianjin

Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sc /ID# 259904, Tianjin, Tianjin

The First Affiliated Hospital, Zhejiang University School of Medicine /ID# 230387, Hangzhou, Zhejiang

The second affiliated hospital of Zhejiang University school of medicine /ID# 231249, Hangzhou, Zhejiang

Zhejiang Cancer hospital /ID# 231388, Hangzhou, Zhejiang

Clinical Hospital Dubrava /ID# 251809, Zagreb, Grad Zagreb

Klinicka bolnica Merkur /ID# 252481, Zagreb, Grad Zagreb

Klinicki bolnicki centar Zagreb /ID# 250709, Zagreb, Grad Zagreb

Klinicki bolnicki centar Rijeka /ID# 251811, Rijeka, Primorsko-goranska Zupanija

Klinicki Bolnicki Centar (KBC) Split - Firule /ID# 250729, Split, Splitsko-dalmatinska Zupanija

Opca bolnica Dr. Josip Bencevic /ID# 251812, Slavonski Brod, Not set

Fakultni nemocnice Brno /ID# 225953, Brno, Not set

Fakultni nemocnice Hradec Kralove /ID# 225955, Hradec Kralove, Not set

Fakultni Nemocnice Ostrava /ID# 225957, Ostrava, Not set

Duplicate_Fakultni Nemocnice v Motole /ID# 225958, Prague, Not set

Fakultni nemocnice Kralovske Vinohrady /ID# 225956, Praha, Not set

Vseobecna fakultni nemocnice v Praze /ID# 225396, Praha, Not set

Rigshospitalet /ID# 226576, Copenhagen Ø, Hovedstaden

Aarhus Universitetshospital - Skejby /ID# 226594, Aarhus, Midtjylland

Roskilde Sygehus /ID# 226597, Roskilde, Sjælland

Odense University Hospital /ID# 226593, Odense C, Syddanmark

Sygehus Lillebalt, Vejle /ID# 226592, Vejle, Syddanmark

CHU de Nice - Hôpital Archet 1 /ID# 226127, Nice, Alpes-Maritimes

Institut Paoli-Calmettes /ID# 226557, Marseille, Bouches-du-Rhone

CHU de Rennes - PONTCHAILLOU /ID# 228207, Rennes, Bretagne

CHU Dijon /ID# 238345, Dijon, Cote-d Or

CHU Limoges - Dupuytren 1 /ID# 234235, Limoges CEDEX 1, Franche-Comte

CHU Montpellier - Hôpital Saint Eloi /ID# 228191, Montpellier Cedex 5, Herault

CHRU Nancy - Hopitaux de Brabois /ID# 226102, Vandoeuvre-les-Nancy, Meurthe-et-Moselle

CHRU Lille - Hopital Claude Huriez /ID# 226101, Lille, Nord

CHU de Nantes, Hotel Dieu -HME /ID# 226125, Nantes, Pays-de-la-Loire

Centre Hospitalier de la Cote Basque /ID# 249143, Bayonne, Pyrenees-Atlantiques

HCL - Hopital Lyon Sud /ID# 227086, Pierre Benite CEDEX, Rhone

CHU Amiens-Picardie Site Sud /ID# 238347, Amiens CEDEX 1, Somme

CHU Poitiers - La miletrie /ID# 226578, Poitiers, Vienne

Chu Angers /Id# 245931, Angers, Not set

CHU de CAEN - Hopital de la Cote de Nacre /ID# 226582, Caen, Not set

Hôpitaux Universitaires Henri Mondor - Hôpital Henri Mondor /ID# 226560, Créteil, Not set

CHD Vendée- La Roche-sur-Yon - Les Oudairies /ID# 243899, La Roche Sur Yon, Not set

CHU Grenoble - Hopital Michallon /ID# 226128, La Tronche, Not set

AP-HP - Hopital Saint-Louis /ID# 226126, Paris, Not set

Centre Henri Becquerel /ID# 226103, Rouen, Not set

Institut Curie - site CLCC René Huguenin /ID# 253519, Saint-cloud, Not set

General Hospital of Athens Laiko /ID# 225399, Athens, Attiki

Alexandra General Hospital /ID# 225402, Athens, Attiki

University General Hospital Attikon /ID# 225401, Athens, Attiki

General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 225416, Athens, Not set

University General Hospital of Ioannina /ID# 225400, Ioannina, Not set

General University Hospital of Thessaloniki AXEPA /ID# 225398, Thessaloniki, Not set

Theageneio Anticancer Hospital /ID# 225516, Thessaloniki, Not set

Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz /ID# 257189, Gyor, Gyor-Moson-Sopron

Debreceni Egyetem-Klinikai Kozpont /ID# 226821, Debrecen, Hajdu-Bihar

Somogy Varmegyei Kaposi Mor Oktato Korhaz /ID# 245938, Kaposvár, Somogy

Vas Varmegyei Markusovszky Egyetemi Oktatokorhaz /ID# 226846, Szombathely, Vas

Semmelweis Egyetem /ID# 227239, Budapest, Not set

Orszagos Onkologiai Intezet /ID# 227294, Budapest, Not set

Szegedi Tudományegyetem /ID# 226838, Szeged, Not set

Tolna Megyei Balassa Janos Korhaz /ID# 250063, Szekszard, Not set

Rambam Health Care Campus /ID# 225981, Haifa, H_efa

Rabin Medical Center /ID# 225862, Haifa, H_efa

Meir Medical Center /ID# 225612, Kfar Saba, HaMerkaz

Assuta Tel Aviv Medical Center /ID# 226066, Tel Aviv, HaMerkaz

The Chaim Sheba Medical Center /ID# 225600, Ramat Gan, Tel-Aviv

Tel Aviv Sourasky Medical Center /ID# 225891, Tel Aviv, Tel-Aviv

Shaare Zedek Medical Center /ID# 259796, Jerusalem, Yerushalayim

Hadassah /ID# 225614, Jerusalem, Yerushalayim

Fondazione di Religione e di Culto Casa Sollievo della Sofferenza /ID# 225554, San Giovanni Rotondo, Foggia

Ospedale San Raffaele IRCCS /ID# 225555, Milan, Milano

IEO -Istituto Europeo di Oncologia /ID# 225545, Milan, Milano

Istituto di Candiolo Fondazione del Piemonte per l'Oncologia IRCCS /ID# 225751, Candiolo, Torino

Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo /ID# 225542, Alessandria, Not set

Centro di Riferimento Oncologico /ID# 225553, Aviano, Not set

ASST Spedali civili di Brescia /ID# 225549, Brescia, Not set

Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRCCS /ID# 252192, Meldola, Not set

Azienda Ospedaliera Universitaria Federico II /ID# 225543, Napoli, Not set

Azienda Ospedaliero Universitaria Maggiore della Carita di Novara /ID# 225773, Novara, Not set

A.O. Ospedali Riuniti Villa Sofia - Cervello /ID# 225541, Palermo, Not set

Ospedale Santa Maria delle Croci /ID# 225571, Ravenna, Not set

NHO Nagoya Medical Center /ID# 230677, Nagoya-shi, Aichi

Aichi Cancer Center Hospital /ID# 226090, Nagoya-shi, Aichi

National Cancer Center Hospital East /ID# 250151, Kashiwa-shi, Chiba

Matsuyama Red Cross Hospital /ID# 251068, Matsuyama-shi, Ehime

National Hospital Organization Kyushu Cancer Center /ID# 251622, Fukuoka-shi, Fukuoka

Kyushu University Hospital /ID# 226091, Fukuoka-shi, Fukuoka

Fukushima Medical University Hospital /ID# 250869, Fukushima-shi, Fukushima

Hokkaido University Hospital /ID# 250149, Sapporo-shi, Hokkaido

Kobe City Medical Center General Hospital /ID# 250597, Kobe-shi, Hyogo

University of Tsukuba Hospital /ID# 251282, Tsukuba-shi, Ibaraki

Kanazawa University Hospital /ID# 251770, Kanazawa-shi, Ishikawa

Kagoshima University Hospital /ID# 250163, Kagoshima-shi, Kagoshima

Tokai University Hospital /ID# 251281, Isehara-shi, Kanagawa

Tohoku University Hospital /ID# 250150, Sendai-shi, Miyagi

Okayama University Hospital /ID# 250161, Okayama-shi, Okayama

Kindai University Hospital /ID# 250160, Osakasayama-shi, Osaka

Osaka University Hospital /ID# 251283, Suita-shi, Osaka

National Cancer Center Hospital /ID# 226089, Chuo-ku, Tokyo

The Cancer Institute Hospital Of JFCR /ID# 230269, Koto-ku, Tokyo

Yamagata University Hospital /ID# 230003, Yamagata-shi, Yamagata

Seoul National University Bundang Hospital /ID# 225763, Seongnam-si, Gyeonggido

Asan Medical Center /ID# 225758, Seoul, Seoul Teugbyeolsi

The Catholic University of Korea, Seoul St. Marys Hospital /ID# 225761, Seoul, Seoul Teugbyeolsi

Ulsan University Hospital /ID# 226971, Ulsan, Ulsan Gwang Yeogsi

Inje University Busan Paik Hospital /ID# 232262, Busan, Not set

Dong-A University Hospital /ID# 228451, Busan, Not set

Keimyung University Dongsan Medical Center /ID# 232264, Daegu, Not set

Jeonbuk National University Hospital /ID# 232263, Jeonju, Not set

Seoul National University Hospital /ID# 225760, Seoul, Not set

Samsung Medical Center /ID# 225759, Seoul, Not set

Flevo Ziekenhuis /ID# 229606, Almere, Flevoland

Gelre Ziekenhuizen /ID# 229762, Apeldoorn, Gelderland

Tergooi /ID# 229772, Hilversum, Noord-Holland

Dijklander Ziekenhuis /ID# 229900, Hoorn Nh, Noord-Holland

Zaans Medisch Centrum /ID# 230614, Zaandam, Noord-Holland

Albert Schweitzer Ziekenhuis /ID# 229560, Dordrecht, Zuid-Holland

Noordwest Ziekenhuisgroep /ID# 230613, Alkmaar, Not set

Meander Medisch Centrum /ID# 229608, Amersfoort, Not set

Vrije Universiteit Medisch Centrum /ID# 225608, Amsterdam, Not set

Onze Lieve Vrouwe Gasthuis /ID# 229761, Amsterdam, Not set

Amphia Ziekenhuis /ID# 229550, Breda, Not set

Haaglanden Medisch Centrum /ID# 229686, Den Haag, Not set

Deventer Ziekenhuis /ID# 229937, Deventer, Not set

Catharina Ziekenhuis /ID# 230465, Eindhoven, Not set

Maxima Medisch Centrum /ID# 225603, Eindhoven, Not set

Medisch Spectrum Twente /ID# 225610, Enschede, Not set

Universitair Medisch Centrum Groningen /ID# 225602, Groningen, Not set

Spaarne Gasthuis /ID# 229621, Haarlem, Not set

Medisch Centrum Leeuwarden /ID# 225605, Leeuwarden, Not set

Leids Universitair Medisch Centrum /ID# 225606, Leiden, Not set

Maastricht Universitair Medisch Centrum /ID# 225607, Maastricht, Not set

St. Antonius Ziekenhuis /ID# 229901, Nieuwegein, Not set

Canisius-Wilhelmina Ziekenhuis /ID# 231291, Nijmegen, Not set

Jeroen Bosch Ziekenhuis /ID# 229765, S Hertogenbosch, Not set

Elisabeth Tweesteden Ziekenhuis /ID# 229773, Tilburg, Not set

Diakonessenhuis /ID# 251793, Utrecht, Not set

North Shore Hospital /ID# 250992, Takapuna, Auckland

Christchurch Hospital /ID# 250993, Christchurch, Canterbury

Wojewodzki Szpital Specjalistyczny im. Janusza Korczaka /ID# 228723, Slupsk, Pomorskie

Swietokrzyskie Centrum Onkologii /ID# 225986, Kielce, Swietokrzyskie

SP ZOZ MSWiA z Warminsko-Mazurskim Centrum Onkologii /ID# 225985, Olsztyn, Warminsko-mazurskie

ARS-MEDICAL Sp. z o.o. /ID# 225848, Pila, Wielkopolskie

Centrum Medyczne Promed - Skorzewo /ID# 227236, Skorzewo, Wielkopolskie

2CA-Braga, Hospital de Braga /ID# 249112, Braga, Not set

IPO Lisboa FG, EPE /ID# 249109, Lisboa, Not set

Centro Hospitalar Universitario de Lisboa Norte, EPE - Hospital de Santa Maria /ID# 249111, Lisboa, Not set

IPO Porto FG, EPE /ID# 249110, Porto, Not set

Pan American Center for Oncology Trials, LLC /ID# 230052, Rio Piedras, Not set

Wits Clinical Research Site /ID# 227799, Johannesburg, Gauteng

Wits Clinical Research Site /ID# 227803, Johannesburg, Gauteng

Alberts Cellular Therapy /ID# 227798, Pretoria, Gauteng

Haemalife Inc. /ID# 243391, Kuilsrivier, Western Cape

Instituto Catalan de Oncologia (ICO) Badalona /ID# 228063, Badalona, Barcelona

Instituto Catalan de Oncologia (ICO) L'Hospitalet /ID# 227393, Hospitalet de Llobregat, Barcelona

Hospital Clinico Universitario Virgen de la Arrixaca /ID# 255381, El Palmar, Murcia

Clinica Universidad de Navarra - Pamplona /ID# 225809, Pamplona, Navarra

Hospital Parc de Salut del Mar /ID# 225810, Barcelona, Not set

Hospital Universitario Vall d'Hebron /ID# 225811, Barcelona, Not set

Hospital Clinic de Barcelona /ID# 226651, Barcelona, Not set

Hospital Santa Creu i Sant Pau /ID# 225813, Barcelona, Not set

Hospital Universitario Reina Sofia /ID# 225806, Cordoba, Not set

CLINICA UNIVERSIDAD DE NAVARRA-Madrid /ID# 228228, Madrid, Not set

Hospital Universitario Infanta Leonor /ID# 225816, Madrid, Not set

MD Anderson Madrid /ID# 225817, Madrid, Not set

Hospital Universitario Ramon y Cajal /ID# 241750, Madrid, Not set

Hospital Universitario Fundacion Jimenez Diaz /ID# 225804, Madrid, Not set

Hospital Universitario 12 de Octubre /ID# 225815, Madrid, Not set

Hospital Clinico Universitario de Valencia /ID# 225818, Valencia, Not set

Skane University Hospital Lund /ID# 227285, Lund, Skane Lan

Sodra Alvsborgs sjukhus /ID# 228885, Boras, Vastra Gotalands Lan

Sahlgrenska University Hospital /ID# 250089, Gothenburg, Vastra Gotalands Lan

Linkoping University Hospital /ID# 233521, Linkoping, Not set

Karolinska Universitetssjukhuset Solna /ID# 229284, Solna, Not set

Kantonsspital Aarau AG /ID# 229112, Aarau, Aargau

Spital Thun /ID# 229499, Thun, Bern

KSW Kantonsspital Winterthur /ID# 241631, Winterthur, Zuerich

Kaohsiung Chang Gung Memorial Hospital /ID# 226670, Kaohsiung City, Kaohsiung

China Medical University Hospital /ID# 226188, Taichung, Not set

Taichung Veterans General Hospital /ID# 226674, Taichung, Not set

National Cheng Kung University Hospital /ID# 226671, Tainan, Not set

Imperial College London - St Mary's Hospital /ID# 242215, London, London, City Of

Norfolk and Norwich University Hospitals NHS Foundation Trust /ID# 226692, Norwich, Norfolk

Conditions: Diffuse Large B-Cell Lymphoma

Learn More ›

A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

NCT04408638

Recruiting

This study will evaluate the efficacy and safety of glofitamab in combination with gemcitabine plus oxaliplatin (Glofit-GemOx) compared with rituximab in combination with gemcitabine plus oxaliplatin (R-GemOx) in patients with R/R DLBCL.

Gender:

All

Ages:

18 years and above

Trial Updated:

04/05/2024

Locations: University of Alabama at Birmingham, Birmingham, Alabama +79 locations

University of Alabama at Birmingham, Birmingham, Alabama

Banner Health MD Anderson AZ, Gilbert, Arizona

Community Cancer Institute (CCI), Fresno, California

Baptist Medical Center - Jacksonville, Jacksonville, Florida

Baptist - MD Anderson Cancer Center, Jacksonville, Florida

Ochsner Medical Center, New Orleans, Louisiana

University of Maryland Medical Center, Baltimore, Maryland

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland

Massachusetts General Hospital, Boston, Massachusetts

University of Mississippi Medical Center, Jackson, Mississippi

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

Icahn School of Medicine at Mount Sinai, New York, New York

Duke University Medical Center, Durham, North Carolina

Allegheny General Hospital, Pittsburgh, Pennsylvania

Providence Regional Cancer Partnership, Everett, Washington

Prince of Wales Hospital; Haematology, Randwick, New South Wales

Royal Adelaide Hospital; Haematology Clinical Trials, Adelaide, South Australia

Monash Health Monash Medical Centre, Clayton, Victoria

St Vincent's Hospital Melbourne, Fitzroy, Victoria

Peter Maccallum Cancer Centre, Melbourne, Victoria

Sir Charles Gairdner Hospital, Nedlands, Western Australia

UZ Gent, Gent, Not set

UZ Leuven Gasthuisberg, Leuven, Not set

CHU Sart-Tilman, Liège, Not set

Beijing Cancer Hospital, Beijing, Not set

Peking University Third Hospital, Beijing, Not set

West China Hospital, Sichuan University, Chengdu, Not set

Sun Yet-sen University Cancer Center, Guangzhou City, Not set

Harbin Medical University Cancer Hospital, Harbin, Not set

Jiangsu Province Hospital, Nanjing, Not set

Fudan University Shanghai Cancer Center, Shanghai City, Not set

Tianjin Cancer Hospital, Tianjin, Not set

Wuhan Union Hospital Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Not set

Zhejiang Cancer Hospital, Zhejiang, Not set

Henan Cancer Hospital, Zhengzhou, Not set

Aarhus Universitetshospital Skejby; Blodsygdomme, Aarhus N, Not set

Rigshospitalet; Hæmatologisk Klinik, København Ø, Not set

Institut Bergonie; Hematologie Oncologie, Bordeaux, Not set

Hopital Henri Mondor; 51 Av Mal Lattre De Tassigny, Creteil, Not set

Hopital Claude Huriez; Hematologie, Lille, Not set

CHU DE MONTPELLIER-ST ELOI; Département d'Hématologie Clinique, Montpellier, Not set

Centre Hospitalier Lyon Sud, Pierre Benite, Not set

CHU Pontchaillou; Service Hématologie, Rennes, Not set

Städtisches Klinikum Dessau, Dessau-Roßlau, Not set

Universitatsklinikum Frankfurt, Frankfurt, Not set

Universitätsklinikum Gießen und Marburg GmbH Standort Gießen Medizinische Klinik I, Giessen, Not set

Universitaetsklinikum Heidelberg, Heidelberg, Not set

Universitaetsklinikum Regensburg, Regensburg, Not set

Katharinenhospital Stuttgart; Klinik für Hämatologie, Onkologie und Palliativmedizin, Stuttgart, Not set

Pusan National University Hospital, Busan, Not set

National Cancer Center, Goyang-si, Not set

Seoul National University Bundang Hospital, Seongnam-si, Not set

Seoul National University Hospital, Seoul, Not set

Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Uniwersyteckie Centrum Kliniczne, Gdansk, Not set

Centrum Onkologii Ziemi Lubelskiej im. ?w. Jana z Dukli, Lublin, Not set

Oddzial Kliniczny Hematologii SPZOZ MSWiA z Warminsko-Mazurskim Centrum Onkologii w Olsztynie, Olsztyn, Not set

Szpital Wojewodzki w Opolu, Oddzial Hematologii i Onkologii Hematologicznej, Opole, Not set

Uniwersytecki Szpital Kliniczny w Poznaniu; Oddzial Hematologii i Transplantacji Szpiku, Pozna?, Not set

Instytut Hematologii i Transfuzjologii; Klinika Hematologii, Warszawa, Not set

Uniwersytecki Szpital Kliniczny; Klinika Hematologii, Nowotworów Krwi i Transplantacji Szpiku, Wroc?aw, Not set

PanOncology Trials; Hospital Oncológico, Puerto Rico Medical Center, San Juan, Not set

Hospital Universitario Marques de Valdecilla; Servicio de Hematologia, Santander, Cantabria

Hospital Universitari Vall d'Hebron; Servicio de Hematologia, Barcelona, Not set

Hospital Clínic i Provincial; Servicio de Hematología y Oncología, Barcelona, Not set

Hospital Universitario la Paz; Servicio de Hematologia, Madrid, Not set

Hospital Universitario Virgen del Rocio; Servicio de Hematologia, Sevilla, Not set

Hospital Clinico Universitario de Valencia; Servicio de Onco-hematologia, Valencia, Not set

Inselspital Bern, Insel-Gruppe AG, Bern, Not set

Universitätsspital Zürich, Zürich, Not set

Chang Gung Medical Foundation - Kaohsiung; Oncology; Division of Hematology-Oncology, Kaoisung, Not set

Chang Gung Medical Foundation - Linkou; Division of Hematology- Oncology, Taoyuan, Not set

Taichung Veterans General Hospital, Xitun Dist., Not set

Beatson West of Scotland Cancer Centre, Glasgow, Not set

St James's Institute of Oncology; Dept of Haematology, Leeds, Not set

UCLH - Clinical Trials Pharmacy B&D Centre, London, Not set

Christie Hospital; Department of Haematology and Transplant, Manchester, Not set

Nottingham City Hospital; Dept of Haematology, Nottingham, Not set

Southampton General Hospital, Southampton, Not set

Conditions: Diffuse Large B-cell Lymphoma

Learn More ›

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

NCT05633615

Recruiting

This phase II trial tests whether mosunetuzumab and/or polatuzumab vedotin helps benefit patients who have received chemotherapy (fludarabine and cyclophosphamide) followed by chimeric antigen receptor (CAR) T-cell therapy (tisagenlecleucel, axicabtagene ciloleucel, or lisocabtagene maraleucel) for diffuse large B-cell lymphoma that has come back (recurrent) or that does not respond to treatment (refractory) or grade IIIb follicular lymphoma. Mosunetuzumab is a monoclonal antibody that may inter... Read More

Gender:

All

Ages:

18 years and above

Trial Updated:

04/03/2024

Locations: Saint Luke's Cancer Institute - Boise, Boise, Idaho +34 locations

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho

Saint Luke's Cancer Institute - Meridian, Meridian, Idaho

Saint Luke's Cancer Institute - Nampa, Nampa, Idaho

Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho

Bronson Battle Creek, Battle Creek, Michigan

Spectrum Health at Butterworth Campus, Grand Rapids, Michigan

Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

West Michigan Cancer Center, Kalamazoo, Michigan

Ascension Borgess Cancer Center, Kalamazoo, Michigan

Trinity Health Muskegon Hospital, Muskegon, Michigan

Cancer and Hematology Centers of Western Michigan - Norton Shores, Norton Shores, Michigan

Spectrum Health Reed City Hospital, Reed City, Michigan

Marie Yeager Cancer Center, Saint Joseph, Michigan

Ascension Providence Hospitals - Southfield, Southfield, Michigan

Munson Medical Center, Traverse City, Michigan

University of Michigan Health - West, Wyoming, Michigan

University of Rochester, Rochester, New York

Wilmot Cancer Institute at Webster, Webster, New York

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Providence Newberg Medical Center, Newberg, Oregon

Providence Willamette Falls Medical Center, Oregon City, Oregon

Providence Portland Medical Center, Portland, Oregon

Providence Saint Vincent Medical Center, Portland, Oregon

Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Cancer Institute - Easley, Easley, South Carolina

Prisma Health Cancer Institute - Butternut, Greenville, South Carolina

Prisma Health Cancer Institute - Faris, Greenville, South Carolina

Prisma Health Cancer Institute - Eastside, Greenville, South Carolina

Prisma Health Cancer Institute - Greer, Greer, South Carolina

Prisma Health Cancer Institute - Seneca, Seneca, South Carolina

Conditions: Diffuse Large B-Cell Lymphoma, Grade 3b Follicular Lymphoma, Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Transformed Follic Lymph to Diff Large B-Cell Lymphoma, Transformed Marg Zone Lymph to Diff Large B-Cell Lymphoma

Learn More ›

Safety and Efficacy Trial of Epcoritamab Combinations in Subjects With B-cell Non-Hodgkin Lymphoma (B-NHL)

NCT04663347

Recruiting

A phase 1b/2, open-label, multinational, interventional trial to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics/biomarkers, immunogenicity, and preliminary efficacy of epcoritamab (EPKINLY™) in combination with other standard of care (SOC) agents in participants with B-cell Non-Hodgkin Lymphoma (B-NHL). The trial consists of 10 different treatment arms. Arm 9 (follicular lymphoma (FL)) is still open for enrolment of new patients, while the other arms have closed thei... Read More

Gender:

All

Ages:

18 years and above

Trial Updated:

04/02/2024

Locations: University of Alabama at Birmingham, Birmingham, Alabama +63 locations

University of Alabama at Birmingham, Birmingham, Alabama

Cedars-Sinai Medical Center, Los Angeles, California

David Geffen School of Medicine at UCLA, Los Angeles, California

University of California San Francisco, San Francisco, California

Dana Farber Cancer Institute, Boston, Massachusetts

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

John Theurer Cancer Center at Hackensack UMC, Hackensack, New Jersey

Mount Sinai, New York, New York

Memorial Sloan Kettering CC, New York, New York

Levine Cancer Center, Charlotte, North Carolina

UMPC Hillman Cancer Center Cancer Pavillion, Pittsburgh, Pennsylvania

UT Southwestern Medical Center, Dallas, Texas

Monash Medical Centre, Clayton, Victoria

Austin Health, Heidelberg, Not set

Linear Clinical Research Limited, Nedlands, Not set

AZ Sint-Jan, Brugge, Not set

Universitair Ziekenhuis Gent, Gent, Not set

CHU UCL Namur Site Godinne, Yvoir, Not set

Fakultni nemocnice Hradec Kralove, Hradec Králové, Not set

Fakultni nemocnice Ostrava, Ostrava - Poruba, Not set

Fakultni nemocnice v Motole, Prague, Not set

Vseobecna Fakultni Nemocnice, Praha 2, Not set

Århus Hospital, Arhus, Not set

Rigshospitalet, Copenhagen, Not set

Odense University Hospital, Odense, Not set

Vejle Sygehus, Vejle, Not set

Tampere University Hospital, Helsinki, Not set

Kuopio University Hospital, Kuopio, Not set

HUS Cancer Center, Lahti, Not set

Institut Bergonié, Bordeaux, Not set

CHU Dijon - Hopital du Bocage, Dijon, Not set

Hopital Claude Huriez - CHRU Lille, Lille, Not set

Hôpital de la Timone, Marseille, Not set

Hôpital Saint-Louis, Paris, Not set

Centre Hospitalier Lyon Sud, Pierre-Bénite, Not set

Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni XXIII), Bergamo, Not set

Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi IRCCS, Bologna, Not set

Fondazione del Piemonte per l Oncologia Istituto di Candiolo IRCCS, Candiolo, Not set

Istituto Scientifico Romagnolo Per Lo Studio e La Cura Dei Tumori, Meldola, Not set

Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico, Milan, Not set

Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

Arcispedale S. Maria Nuova Azienda Ospedaliera di Reggio Emilia, Reggio Emilia, Not set

Amsterdam UMC, Locatie VUMC, Amsterdam, Not set

Universitair Medisch Centrum Groningen (UMCG), Groningen, Not set

Leids Universitair Medisch Centrum, Leiden, Not set

Maastricht University Medical Center, Maastricht, Not set

Erasmus Medisch Centrum, Rotterdam, Not set

UMC Utrecht, Utrecht, Not set

Oslo Universitetssykehus HF, Radiumhospitalet, Oslo, Not set

ICO l Hospitalet, Barcelona, Not set

Hospital Universitari Vall d'Hebron, Barcelona, Not set

Hospital Universitario Fundacion Jimenez Diaz, Madrid, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital Universitario de Salamanca, Salamanca, Not set

Södra Älvsborgs Sjukhus, Borås, Not set

Sahlgrenska Sjukhuset, Göteborg, Not set

Skånes Universitetssjukhus, Lund, Not set

Karolinska Universitetssjukhuset, Solna, Not set

Norrlands Universitetssjukhus, Umeå, Not set

Akademiska Sjukhuset, Uppsala, Not set

University College London Hospitals, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Freeman Hospital, Newcastle Upon Tyne, Not set

Derriford Hospital, Plymouth, Not set

Conditions: Diffuse Large B-Cell Lymphoma, Follicular Lymphoma

Learn More ›

Effects of Maplirpacept (PF-07901801),Tafasitamab, and Lenalidomide in People With Relapsed or Refractory Diffuse Large B-cell Lymphoma

NCT05626322

Recruiting

The purpose of this study is to learn about the effects of three study medicines [maplirpacept (PF-07901801), tafasitamab, and lenalidomide] when given together for the treatment of diffuse large B-cell lymphoma (DLBCL) that: is relapsed (has returned after last treatment) or is refractory (has not responded to last treatment) DLBCL is a type of non-Hodgkin lymphoma (NHL). NHL is a cancer of the lymphatic system. It develops when the body makes abnormal lymphocytes. These lymphocytes are a type of white blood cell that normally help to fight infections. This study is seeking participants who are unable or unwilling to undergo an autologous stem cell transplantation (when doctors put healthy blood cells back into your body) or CAR-T immune cell therapy. Everyone in this study will receive three medicines: maplirpacept (PF-07901801), tafasitamab and lenalidomide. Participants will receive maplirpacept (PF-07901801) and tafasitamab at the study clinic by intravenous (IV) infusion (given directly into a vein) and lenalidomide will be taken by mouth at home. Study interventions will be administered in 28-day cycles. Maplirpacept (PF-07901801) will be given weekly for the first three cycles and then every two weeks. Tafasitamab will administered on Days 1, 4, 8, 15 and 22 in cycle 1, weekly in cycles 2 and 3 and then every 2 weeks in cycle 4 and beyond. Lenalidomide will be taken every day for Days 1 to 21 of each 28-day cycle for the first 12 cycles. Participants can continue to take maplirpacept (PF-07901801) and tafasitamab until their lymphoma is no longer responding. Lenalidomide is discontinued after 12 cycles. Maplirpacept (PF-07901801) will be given at different doses to different participants. Everyone taking part will receive approved doses of tafasitamab and lenalidomide. We will compare the experiences of people receiving different doses of PF-07901801. This will help us to determine what dose is safe and effective when combined with the other 2 study medicines. Read Less

Gender:

All

Ages:

18 years and above

Trial Updated:

03/29/2024

Locations: Winship Cancer Institute, Atlanta, Georgia +22 locations

Conditions: Diffuse Large B-Cell Lymphoma

Learn More ›

A Study to Learn About the Effects of Two Study Medicines (Maplirpacept [PF-07901801] And Glofitamab) When Given Together In People With Relapsed Or Refractory Diffuse Large B Cell Lymphoma.

NCT05896163

Recruiting

The purpose of this study is to learn about the effects of two study medicines (maplirpacept [PF-07901801] and glofitamab) when given together for the treatment of diffuse large B-cell lymphoma (DLBCL) that is relapsed or is refractory. Relapsed means has returned after last treatment. Refractory means that it has not responded to last treatment. The two study medicines are given after a single dose of obinutuzumab which is the third study medicine. DLBCL is a type of non-Hodgkin lymphoma (NHL). NHL is a cancer of the lymphatic system. It develops when the body makes abnormal B lymphocytes. These lymphocytes are a type of white blood cell that normally help to fight infections. This study is seeking adult participants who: Have histologically confirmed diagnosis of DLBCL Have received at least one first line of treatment for NHL. Are unable or unwilling to undergo a stem cell transplant or CAR-T cell therapy. Stem cell transplant is a procedure in which a patient receives healthy blood-forming cells to replace their own stem cells that have been destroyed by treatment. A CAR-T therapy is a type of treatment in which a patient's T cells are changed in the laboratory so they will attack cancer cells. Everyone in this study will receive all three medicines at the study site by intravenous (IV) infusion which is given directly into a vein. The two study medicines (maplirpacept [PF-07901801] and glofitamab) will be given in 21-day cycles. At Cycle 0, participants will receive a single dose of obinutuzumab pre-treatment followed by two step-up doses of glofitamab. The combination of maplirpacept (PF-07901801) with glofitamab full dose will be administered for the first time at Cycle 1 Day 1. Maplirpacept (PF-07901801) will be given weekly for the first three cycles and then every three weeks. Glofitamab will be given every 3 weeks for approximately 9 months. Thereafter participants will continue to receive maplirpacept alone. Maplirpacept (PF-07901801) will be given at different doses to different participants. Everyone taking part will receive the same fixed doses of glofitamab and obinutuzumab studied in patients with DLBCL. The study will compare the experiences of people receiving different doses of maplirpacept (PF-07901801). This will help to determine what dose is safe and effective when given with the other 2 study medicines. Read Less

Gender:

All

Ages:

18 years and above

Trial Updated:

03/29/2024

Locations: Allina Health Cancer Institute - Abbott Northwestern Hospital, Minneapolis, Minnesota +11 locations

Conditions: Diffuse Large B-Cell Lymphoma

Learn More ›

Selinexor (KPT-330) in Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

NCT02227251

Recruiting

A multicenter, open-label Phase 2b study of selinexor (KPT-330) in participants with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) who have no therapeutic options of demonstrated clinical benefit.

Gender:

All

Ages:

18 years and above

Trial Updated:

03/27/2024

Locations: UACC Arizona, Tucson, Arizona +175 locations

UACC Arizona, Tucson, Arizona

University of California San Francisco, San Francisco, California

University of California Los Angeles (UCLA), Santa Monica, California

Boca Raton Cancer Research Medical Center, Plantation, Florida

University of Chicago, Chicago, Illinois

Robert H. Lurie Comprehensive Cancer Center/Northwestern University, Chicago, Illinois

Norton Cancer Institute, Louisville, Kentucky

Dana Farber Cancer Institute, Boston, Massachusetts

Tufts Medical Center, Boston, Massachusetts

Lahey Clinic, Burlington, Massachusetts

University of Massachusetts Medical School, Worcester, Massachusetts

John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, New Jersey

Clinical Research Alliance, Lake Success, New York

New York Presbyterian Hospital/ Cornell Medical College, New York, New York

Stony Brook University Hospital, Stony Brook, New York

Gabrail Cancer Center, Canton, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

University Hospitals Seidman Cancer Center, Cleveland, Ohio

University of Oklahoma, Oklahoma City, Oklahoma

Greenville Hospital System, Greenville, South Carolina

MD Anderson, Houston, Texas

Swedish Cancer Institute, Seattle, Washington

Virginia Mason Hospital & Medical Center, Seattle, Washington

St. Vincent's Hospital Sydney, Darlinghurst, New South Wales

Liverpool Hospital, Ingham Institute of Medical Research, Liverpool, New South Wales

Calvary Mater Newcastle Hospital, Waratah, New South Wales

Icon Cancer Care, South Brisbane, Queensland

Royal Adelaide Hospital, Adelaide, South Australia

Ashford Cancer Centre, Kurralta Park, South Australia

Monash Medical Centre, Clayton, Victoria

Epworth Hospital, East Melbourne, Victoria

St. Vincent's Melbourne, Fitzroy, Victoria

The Alfred Hospital, Melbourne, Victoria

Fiona Stanley Hospital, Murdoch, Western Australia

Medical University of Graz, Graz, Not set

Medizinische Universität Innsbruck für Innere Medizin, Innsbruck, Not set

LKH Leoben Department for Haemato-Oncology, Leoben, Not set

Akh Linz Innere Med III - Zentrum für Hämatologie und med. Onkologie, Linz, Not set

Krankenhaus Barmherzigen Schwestern Linz, Linz, Not set

Krankenhaus der Elisabethinen Linz GmbH, Linz, Not set

Uni. Klinik für Innere Medizin III Universitätsklinikum der PMU LKH Salzburg, Salzburg, Not set

Medical University of Vienna (MUW) Department of Medicine I, Vienna, Not set

Univ. General Hospital Hietzing, Vienna, Not set

Ziekenhuis Netwerk Antwerpen, Antwerpen, Not set

AZ Sint-Jan, Bruges, Not set

Institut Jules Bordet, Brussels, Not set

Cliniques Universitaires Saint-Luc, Brussels, Not set

UZ Gent, Gent, Not set

CH Jolimont, La Louviere, Not set

AZ Delta, Roeselare, Not set

H-Hartziekenhuis Roeselare-Menen, Roeselare, Not set

University Hospital for Active Treatment Dr. Georgi Stranski, Pleven, Not set

University Multiprofile Hospital for Active Treatment Sveti Ivan Rilski EAD, Sofia, Not set

Specialized Hospital for Active Treatment of Haematological Diseases EAD, Sofia, Not set

Princess Margaret Cancer Centre, Toronto, Ontario

Sir Mortimer B Davis Jewish General Hospital/McGill University, Montreal, Quebec

CHU Lyon Sud, Pierre-Bénite, Lyon

Centre Hospitalier Universitaire Henri Mondor, Créteil, Not set

Unite Hemopathies Lymphoides Chu Henri Mondor, Créteil, Not set

Chu Dijon-Bourgogne - Hematologie Clinique, Dijon, Not set

Hospitalier de la Rochelle-Ré-Aunis, La Rochelle, Not set

CHRU de Lille - Hopital Claude-Huriez, Lille, Not set

Marseille Institute of Cancer - Institut J. Paoli and I. Calmettes, Marseille, Not set

CHU Montpellier, Montpellier, Not set

Hostpial Saint Louis - CIRCO (Centre d'Investigations et de Recherche Clinique en Oncologie), Paris, Not set

Hôpital Necker Service d'Hématologie Adult, Paris, Not set

Pitié-Salpêtrière Hospital, Paris, Not set

Centre Henri Becquerel, Rouen, Not set

Uniklinik Aachen Klinik für Hämatologie, Onkologie, Hämostaseologie und Stammzelltransplantation, Aachen, Not set

HELIOS Klinikum Bad Saarow, Bad Saarow, Not set

Charite Universitatsmedizin Berlin (Benjamin Franklin Campus), Berlin, Not set

Charite Universitatsmedizin Berlin (Virchow Campus), Berlin, Not set

Ev. Diakonie-Krankenhaus gGmbH, Bremen, Not set

Gemeinschaftspraxis Haematologie and Onkologie-Dresden, Dresden, Not set

Martin-Luther-University Halle-Wittenberg Department of Oncology, Halle, Not set

Medizinische Hochschule, Hannover, Not set

Universität Heidelberg Medizinische Klinik V Hämatologie, Onkologie und Rheumatologie, Heidelberg, Not set

Klinikum Kempten Klinik für Innere Medizin III - Hämatologie, Onkologie und Palliativmedizin, Koln, Not set

Klinikum Leverkusen, Leverkusen, Not set

Klinikum Ludwigshafen, Ludwigshafen, Not set

Rotkreuzklinikum München, Muenchen, Not set

Klinikum Nürnberg Nord, Nuernberg, Not set

Haematology Department and HCT Unit G.Papanicolaou Hospital, Exochi, Thessaloniki

Hematology Clinic,General Hospital of Athens,G. Gennimatos, Athens, Not set

National & Kapodistrian University of Athens, Laiko General Hospital, Athens, Not set

Hematology Department Laiko General Hospital, Athens, Not set

Second Depth of Internal Medicine, Attiko University Hospital, Athens, Not set

National & Kapodistrian University of Athens, Attiko University Hospital, Chaidari, Not set

Department of clinical hematology ,university hospital Ioannina, Ioánnina, Not set

University of Patras Medical School, Patras, Not set

Semmelweis Egyetem Általános Orvosi Kar, Budapest, Not set

Országos Onkológiai Intézet "A" Belgyógyászati Onkológiai Osztály, Budapest, Not set

Semmelweis University Department of Medicine and Oncology, Budapest, Not set

Somogy Megyei Kaposi Mór Oktató Kórház, Kaposvár, Not set

Pécsi Tudományegyetem, ÁOK, I. számú Belgyógyászati Klinika, Pécs, Not set

Veszprém Megyei Csolnoky Ferenc Kórház, Veszprém, Not set

CSolnoky ferenc Hospital, Veszprém, Not set

Regional Cancer Centre, IGIMS, Patna, Bihar

SRM Institutes for Medical Science, Vadapalani, Chennai

Rajiv Gandhi Cancer Hospital, New Delhi, Delhi

Regional Cancer Centre, Thiruvananthapuram, Kerala

Prince Aly Khan Hospital, Mumbai, Maharashtra

Jaslok Hospital and Research Centre, Mumbai, Maharashtra

Deenanath Mangeshkar Hospital, Pune, Maharashtra

Institute of Medical Sciences & SUM Hospital, Bhubaneswar, Odisha

Dayanand Medical College and Hospital, Ludhiāna, Punjab

Cancer Institute (WIA), Chennai, Tamil Nadu

Saveetha Medical College Hospital, Chennai, Tamil Nadu

G. Kuppu Swamy Naidu Hospital, Coimbatore, Tamil Nadu

Meenakshi Mission Hospital & Research Centre, Madurai, Tamil Nadu

King George's Medical University (KGMU), Lucknow, Uttar Pradesh

Nil Ratan Sircar Medical College and Hospital, Kolkata, West Bengal

Netaji Subhas Chandra Bose Cancer Research Hospital, Kolkata, West Bengal

TATA Memorial Centre, Kolkata, West Bengal

Netaji Subhas Chandra Bose Cancer Research Institute, Kolkata, West Bengal

IRCH, All India Institute of Medical Sciences, Delhi, Not set

Dr. B.R.A. Institute Rotary Cancer Hospital All India Institute of Medical Sciences, New Delhi, Not set

Hematology-Soroka, Beer Sheva, Not set

Rambam Healthcare Campus, Haifa, Not set

Wolfson MC, Holon, Not set

Hadassah Medical Center, Jerusalem, Not set

Rabin Medical Center, Petach Tikva, Not set

Assuta Medical Center, Tel Aviv, Not set

TLV Sorasky Medical Center, Tel Aviv, Not set

Sheba Medical Center, Tel Hashomer, Not set

Instituto di Ematologia Seragnoli Pad 8 Universita di Bologna, Bologna, Not set

SODc Ematologica ,AOU Careggi, Florence, Not set

AOU Maggiore della Carità SCDU Ematologia, Florence, Not set

Hematology-Oncology & Stem Cell Transplantation Unit, National Cancer Institute, Fondazione 'G. Pascale', IRCCS, Naples, Not set

SCDU Ematologia, Division of Hematology, Dept. of Translational Medicine, Universita del Piemonte Orientale, Novara, Not set

Fondazione Policlinico Universitario A. Gemelli, Rome, Not set

Azienda Ospedaliero-Universitaria Senese, Siena, Not set

Città della Salute e della Scienza di Torino, Torino, Not set

VUMc (Vrije Universiteit Amsterdam), Amsterdam, Not set

LUMC (leidse universitair medisch centrum), Leiden, Not set

North Shore Hospital, Auckland, Not set

Christchurch Hospital, Christchurch, Not set

Uniwersytecki Szpital Kliniczny im. Jana Mikulicza, Wrocław, Radeckiego

Szpitale Wojewódzkie w Gdyni, Gdyńskie Centrum onkologii, Gdynia, Not set

MCM (Małopolskie Centrum Medyczne), Krakow, Not set

Wojewodzki Szpital Specjalistyczny w Legnicy, Legnica, Not set

Samodzielny Publiczny Szpital Kliniczny nr 1 w Lublinie, Lublin, Not set

Hematology Department St John's Cancer Centre, Lublin, Not set

Samodzielny Publiczny Zakład Opieki Zdrowotnej Ministerstwa, Olsztyn, Not set

Instytut Hematologii i Transfuzjologii, Warszawa, Not set

Centrum Onkologii- Insytut Im. Marii Skłodowskiej-Curie Klinika Nowotworow Ukladu Chlonnego, Warszawa, Not set

Maria Sklodowska Curie National Research Institute, Warszawa, Not set

Memorial Provincial Specialist Hospital in Lodz, Łódź, Not set

Institut za onkologiju i radiologiju Srbije, Belgrade, Not set

Klinicko Bolnick Centar Zemun Odeljenje hematologije, Belgrade, Not set

Klinički centar Srbije Klinika za hematologiju, Belgrade, Not set

Kliničko bolnički centar Zvezdara, Belgrade, Not set

Klinički centar Niš Klinika za hematologiju, Nis, Not set

Institut za onkologiju Vojvodine, Sremska Kamenica, Not set

Hospitla Universitari Germans Trias i Pujol - ICO, Badalona, Not set

Hospital University Vall d'Hebron, Barcelona, Not set

Hospital Clinic i Provincial de Barcelona, Barcelona, Not set

Hospital Universitario La Paz, Madrid, Not set

Hospital de Son Llàtzer, Palma de Mallorca, Not set

Clínica Universidad De Navarra, Pamplona, Not set

Hospital Universitario de Salamanca, Salamanca, Not set

Hospital Universitario Virgen del Rocio, Sevilla, Not set

Gloucestershire Royal Hospital, Gloucester, Gloucestershire

Southampton University Hospital, Southampton, Hampshire

Royal Marsden Hospital, Sutton, London

Northwick Park Hospital, Harrow, Middlesex

Leeds Teaching Hospitals NHS Trust, Leeds, Yorkshire

Addenbrooke's Hospital Cambridge, Cambridge, Not set

Royal Liverpool University Hospital, Liverpool, Not set

The Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, Not set

King's College Hospital, London, Not set

Princess Royal University Hospital (PRUH), London, Not set

Guy's and St Thomas' NHS Foundation Trust, London, Not set

The Christie NHS Foundation Trust, Manchester, Not set

Oxford University Hospitals NHS Trust Oxford Cancer and Haematology Centre, Churchill Hospital, Oxford, Not set

Derriford Hospital, Plymouth, Not set

Conditions: Diffuse Large B-cell Lymphoma

Learn More ›

realMIND: Observational Study on Safety and Effectiveness of Tafasitamab in Combination With Lenalidomide in Patients With Relapsed or Refractory DLBCL

NCT04981795

Recruiting

The realMIND study is a multicenter, observational study intended to further characterize the safety and effectiveness data of US patients (with a focus on racial and ethnic minority patients) with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL), treated with tafasitamab in combination with lenalidomide.

Gender:

All

Ages:

18 years and above

Trial Updated:

03/21/2024

Locations: Alabama Oncology, Birmingham, Alabama +23 locations

Conditions: Diffuse Large B-cell Lymphoma

Learn More ›

Selinexor Plus Combination Chemotherapy in Treating Patients With Advanced B Cell Non-Hodgkin Lymphoma

NCT03147885

Recruiting

This phase Ib/II trial is aimed at studying the combination of a drug named Selinexor (selective inhibitor of nuclear export) in combination with standard therapy for B cell Non-Hodgkin's lymphoma called R-CHOP. The investigators will establish maximum tolerated dose of Selinexor in combination with RCHOP and also study the efficacy of this combination for therapy of B cell Non-Hodgkin's lymphoma. Giving Selinexor plus chemotherapy may work better in treating patients with B cell non-Hodgkin lym... Read More

Gender:

All

Ages:

18 years and above

Trial Updated:

03/19/2024

Locations: Barbara Ann Karmanos Cancer Institute, Detroit, Michigan

Conditions: Diffuse Large B-Cell Lymphoma, Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Extranodal Marginal Zone Lymphoma, Recurrent Follicular Lymphoma, Recurrent Indolent Adult Non-Hodgkin Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Waldenstrom Macroglobulinemia, Refractory B-Cell Non-Hodgkin Lymphoma, Refractory Extranodal Marginal Zone Lymphoma, Refractory Follicular Lymphoma, Refractory Mantle Cell Lymphoma, Stage III Non-Hodgkin Lymphoma, Stage IV Non-Hodgkin Lymphoma, Transformed Recurrent Non-Hodgkin Lymphoma

Learn More ›

Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Previously Untreated Lymphoma

NCT04479267

Recruiting

This phase II trial studies how well polatuzumab vedotin and combination chemotherapy work in treating patients with previously untreated double, triple hit lymphoma, Double Expressor Lymphoma or High-Grade B Cell Lymphoma. Polatuzumab vedotin is a monoclonal antibody that works by binding with cancer cells and releasing another chemotherapy drug, called monomethyl auristatin E, into the cell causing the cancer cells to die or stop growing. Chemotherapy drugs, such as rituximab, cyclophosphamide... Read More

Gender:

All

Ages:

18 years and above

Trial Updated:

03/19/2024

Locations: Karmanos Cancer Institute, Detroit, Michigan

Conditions: Diffuse Large B-Cell Lymphoma, High Grade B-Cell Lymphoma w/MYC & BCL2 or BCL6 Rearrangements, High Grade B-Cell Lymphoma w/MYC, BCL2 & BCL6 Rearrangements, Double Expressor Lymphoma, High-grade B-cell Lymphoma

Learn More ›

13 - 24 of 33