Multiple Myeloma Clinical Trials

A listing of 183 Multiple Myeloma clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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There are currently 183 active clinical trials seeking participants for Multiple Myeloma research studies. The states with the highest number of trials for Multiple Myeloma participants are California, New York, Ohio and Texas.

Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

Learn More

* Compensation for time may be available

Featured Trial

Chronic Cough Research Study

Recruiting

Are you tired of living with chronic cough? Our research study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough.
You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you!

Conditions:

Chronic Cough

Refractory or Unexplained Chronic Cough

Cough

Asthma

Sinusitis

Learn More

Featured Offer

Lose Weight with GLP-1 Medications

Recruiting

Policy Lab has partnered with OnlineSemaglutide.org to offer trusted access to semaglutide and other GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.

GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.

As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

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Featured Trial

Stroke Clinical Study

Recruiting

A clinical study for people that suffer with Stroke

Conditions:

Stroke

Learn More

Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

NCT06158841

Recruiting

Multiple myeloma (MM) is a cancer of the blood's plasma cells. The cancer is typically found in the bones and bone marrow (the spongy tissue inside of the bones) and can cause bone pain, fractures, infections, weaker bones, and kidney failure. Treatments are available, but MM can come back (relapsed) or may not get better (refractory) with treatment. This is a study to determine change in disease symptoms of etentamig compared to standard available therapies in adult participants with relapsed/r... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/13/2025

Locations: University of Alabama at Birmingham - Main /ID# 261434, Birmingham, Alabama +156 locations

University of Alabama at Birmingham - Main /ID# 261434, Birmingham, Alabama

Mayo Clinic Hospital - Phoenix /ID# 263326, Phoenix, Arizona

Alta Bates Summit Medical Center for Research /ID# 261438, Berkeley, California

Providence - St. Jude Medical Center /ID# 262031, Fullerton, California

VA Loma Linda Healthcare System /ID# 261015, Loma Linda, California

Cedars-Sinai Medical Center /ID# 261008, Los Angeles, California

Mayo Clinic Hospital Jacksonville /ID# 263324, Jacksonville, Florida

Cancer Specialists of North Florida - Jacksonville - AC Skinner Parkway /ID# 246230, Jacksonville, Florida

Winship Cancer Institute of Emory University /ID# 262525, Atlanta, Georgia

University of Illinois at Chicago /ID# 246349, Chicago, Illinois

Nancy W. Knowles Cancer Center /ID# 271361, Elmhurst, Illinois

Springfield Clinic /ID# 262266, Springfield, Illinois

Our Lady Of The Lake Regional Medical Center /ID# 272780, Baton Rouge, Louisiana

Center for Cancer and Blood Disorders-American Oncology Partners of Maryland /ID# 263637, Bethesda, Maryland

Beth Israel Deaconess Medical Center /ID# 271535, Boston, Massachusetts

Dana-Farber Cancer Institute /ID# 261554, Boston, Massachusetts

Regents of the University of Michigan /ID# 261577, Ann Arbor, Michigan

Karmanos Cancer Institute - Detroit /ID# 266298, Detroit, Michigan

Henry Ford Hospital /ID# 262704, Detroit, Michigan

Barbara Ann Karmanos Cancer Institute - McLaren Greater Lansing /ID# 259891, Lansing, Michigan

Mayo Clinic - Rochester /ID# 246228, Rochester, Minnesota

University of Missouri Hospital /ID# 261553, Columbia, Missouri

New York Cancer & Blood Specialists - Bay Shore /ID# 261524, Bay Shore, New York

Eastchester Center for Cancer Care /ID# 262952, Bronx, New York

New York Cancer & Blood Specialists - Lake Success Medical Oncology /ID# 262953, New Hyde Park, New York

New York Cancer and Blood Specialists - New York /ID# 262951, New York, New York

University of North Carolina /ID# 259854, Chapel Hill, North Carolina

Levine Cancer Institute /ID# 246199, Charlotte, North Carolina

Duke University Medical Center /ID# 259694, Durham, North Carolina

University Of Cincinnati Medical Center /ID# 246415, Cincinnati, Ohio

Cleveland Clinic Main Campus /ID# 246183, Cleveland, Ohio

Medical University of South Carolina /ID# 259692, Charleston, South Carolina

University of Tennessee Health Science Center /ID# 261622, Memphis, Tennessee

Baptist Memorial Hospital /ID# 270910, Memphis, Tennessee

The West Clinic /ID# 262444, Memphis, Tennessee

Vanderbilt University Medical Center /ID# 261621, Nashville, Tennessee

Virginia Cancer Specialists - Fairfax /ID# 262792, Fairfax, Virginia

VCU Massey Cancer Center: Dalton Oncology Clinic /ID# 261944, Richmond, Virginia

Northwest Medical Specialties Tacoma /ID# 276281, Tacoma, Washington

St George Hospital /ID# 261806, Kogarah, New South Wales

Liverpool Hospital /ID# 262159, Liverpool, New South Wales

Calvary Mater Newcastle /ID# 261804, Waratah, New South Wales

Princess Alexandra Hospital /ID# 261810, Woolloongabba, Queensland

Monash Health - Monash Medical Centre /ID# 262158, Clayton, Victoria

St Vincent's Hospital Melbourne /ID# 261808, Fitzroy Melbourne, Victoria

Box Hill Hospital /ID# 262784, Melbourne, Victoria

Universitaetsklinikum Krems /ID# 261509, Krems an der Donau, Niederoesterreich

Ordensklinikum Linz GmbH Elisabethinen /ID# 245609, Linz, Oberoesterreich

Medizinische Universitaet Graz /ID# 261908, Graz, Steiermark

Klinik Ottakring /ID# 245829, Vienna, Wien

Algemeen Ziekenhuis klina /ID# 260856, Brasschaat, Antwerpen

AZ Sint-Jan Brugge /ID# 245345, Brugge, West-Vlaanderen

University Health Network_Princess Margaret Cancer Centre /ID# 261566, Toronto, Ontario

Beijing Chaoyang Hospital,Capital Medical University /ID# 245533, Beijing, Beijing

Peking Union Medical College Hospital (East) - Dongdan Campus /ID# 245545, Beijing, Beijing

Fujian Medical University Union Hospital /ID# 245558, Fuzhou, Fujian

Sun Yat-Sen University Cancer Center /ID# 245542, Guangzhou, Guangdong

People's Hospital of Henan Province /ID# 260918, Zhengzhou, Henan

Henan Cancer Hospital /ID# 245536, Zhengzhou, Henan

Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 245549, Wuhan, Hubei

Zhongda Hospital Southeast University /ID# 245563, Nanjing, Jiangsu

The First Affiliated Hospital of Soochow University /ID# 245544, Suzhou, Jiangsu

The First Affiliated Hospital of Nanchang University /ID# 245537, Nanchang, Jiangxi

The First Hospital of China Medical University /ID# 245547, Shenyang, Liaoning

Second Affiliated Hospital of Xian Jiaotong University /ID# 261255, Xi'an, Shaanxi

Shanghai Tongji Hospital /ID# 245539, Shanghai, Shanghai

Institute of Hematology and Blood Diseases Hospital /ID# 265702, Tianjin, Tianjin

Tianjin Medical University General Hospital /ID# 260851, Tianjin, Tianjin

The First Affiliated Hospital, Zhejiang University School of Medicine /ID# 260883, Hangzhou, Zhejiang

Sir Run Run Shaw Hospital Zhejiang University School of Medicine /ID# 260882, Hangzhou, Zhejiang

The First Affiliated Hospital of Wenzhou Medical University /ID# 245550, Wenzhou, Zhejiang

Fakultní Nemocnice Brno - Jihlavská /ID# 245689, Brno, Brno-mesto

Fakultní nemocnice Hradec Králové - Sokolská /ID# 245690, Hradec Králové, Hradec Kralove

Fakultni Nemocnice Ostrava /ID# 245686, Ostrava, Ostrava-mesto

Všeobecná Fakultní Nemocnice v Praze /ID# 245691, Praha, Praha 17

Odense University Hospital /ID# 260924, Odense, Syddanmark

Sygehus Lillebalt, Vejle /ID# 260923, Vejle, Syddanmark

Ch Saint Quentin /Id# 261856, St Quentin CEDEX, Aisne

Centre Hospitalier du Mans /ID# 261852, Le Mans CEDEX 9, Sarthe

CH Henri Duffaut /ID# 261844, Avignon CEDEX 9, Vaucluse

Centre Hospitalier Régional d'Orléans - Hôpital de la Source /ID# 261854, Orléans, Not set

Universitaetsklinikum Freiburg /ID# 262147, Freiburg, Baden-Wuerttemberg

Staedtisches Klinikum Karlsruhe /ID# 272377, Karlsruhe, Baden-Wuerttemberg

Klinikum Chemnitz - Flemmingstraße /ID# 273108, Chemnitz, Sachsen

Charite Universitaetsklinikum Berlin - Campus Benjamin Franklin /ID# 260689, Berlin, Not set

Centrum fuer Haematologie und Onkologie Bethanien /ID# 271982, Frankfurt am Main, Not set

Universitaetsklinikum Hamburg-Eppendorf /ID# 260651, Hamburg, Not set

Alexandra General Hospital /ID# 240591, Athens, Attiki

University General Hospital Attikon /ID# 240592, Athens, Attiki

General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 240596, Athens, Not set

General University Hospital of Thessaloniki AXEPA /ID# 240595, Thessaloniki, Not set

Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz /ID# 261648, Gyor, Gyor-Moson-Sopron

Semmelweis Egyetem /ID# 261647, Budapest, Not set

Del-pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet /ID# 261646, Budapest, Not set

The Chaim Sheba Medical Center /ID# 245497, Ramat Gan, Tel-Aviv

Tel Aviv Sourasky Medical Center /ID# 245495, Tel Aviv, Tel-Aviv

Shaare Zedek Medical Center /ID# 245681, Jerusalem, Yerushalayim

Rabin Medical Center /ID# 245498, Petah Tikva, Not set

ASST Ovest Milanese /ID# 256813, Legnano, Milano

A.O.U. CITTA' DELLA SALUTE E DELLA SCIENZA DI TORINO - Ospedale Molinette /ID# 256808, Torino, Piemonte

Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 256810, Rome, Roma

Azienda Ospedaliero Universitaria delle Marche /ID# 256812, Ancona, Not set

AOU Policlinico G. Rodolico - San Marco /ID# 256814, Catania, Not set

Anjo Kosei Hospital /ID# 263434, Anjo, Aichi

Nagoya City University Hospital /ID# 263320, Nagoya, Aichi

Chiba University Hospital /ID# 262006, Chiba-shi, Chiba

University of Fukui Hospital /ID# 264222, Yoshida-gun, Fukui

Kyushu University Hospital /ID# 264704, Fukuoka-shi, Fukuoka

Gifu Municipal Hospital /ID# 263321, Gifu-shi, Gifu

Gunma University Hospital /ID# 262580, Maebashi-shi, Gunma

Chugoku Central Hospital /ID# 263431, Fukuyama, Hiroshima

Hyogo Prefectural Amagasaki General Medical Center /ID# 265696, Amagasaki, Hyogo

University Hospital Kyoto Prefectural University of Medicine /ID# 262585, Kyoto-shi, Kyoto

Miyagi Cancer Center /ID# 265094, Natori, Miyagi

Naha City Hospital /ID# 263972, Naha, Okinawa

The University of Osaka Hospital /ID# 263974, Suita-shi, Osaka

Saitama Prefectural Cancer Center /ID# 262586, Kitaadachi-gun, Saitama

Japanese Red Cross Medical Center /ID# 261717, Shibuya-ku, Tokyo

Seoul National University Hospital /ID# 245491, Seoul, Seoul Teugbyeolsi

Samsung Medical Center /ID# 245492, Seoul, Seoul Teugbyeolsi

The Catholic University of Korea, Seoul St. Marys Hospital /ID# 245493, Seoul, Seoul Teugbyeolsi

Ulsan University Hospital /ID# 245490, Ulsan, Ulsan Gwang Yeogsi

Yonsei University Health System Severance Hospital /ID# 245489, Seoul, Not set

Uniwersytecki Szpital Kliniczny We Wrocławiu /ID# 260172, Wroclaw, Dolnoslaskie

Uniwersytecki Szpital Kliniczny Nr 1 w Lublinie /ID# 260168, Lublin, Lubelskie

Uniwersyteckie Centrum Kliniczne /ID# 260169, Gdansk, Pomorskie

Fundacao Champalimaud /ID# 246258, Lisbon, Lisboa

Unidade Local de Saude de Santa Maria, EPE /ID# 246255, Lisboa, Not set

Instituto Portugues de Oncologia do Porto Francisco Gentil, EPE /ID# 246257, Porto, Not set

Hematology And Oncology Institute /ID# 272531, Manati, Not set

Auxilio Mutuo Cancer Center /ID# 272565, San Juan, Not set

Alberts Cellular Therapy /ID# 245725, Pretoria, Gauteng

Constantiaberg Haematology /ID# 261320, Cape Town, Western Cape

Haemalife Inc. /ID# 245724, Kuilsrivier, Western Cape

Instituto Catalan de Oncologia (ICO) Badalona /ID# 246398, Badalona, Barcelona

Complejo Hospitalario Universitario Ourense /ID# 246400, Orense, Ourense

Hospital de Leon /ID# 261624, Leon, Not set

Hospital General Universitario Gregorio Maranon /ID# 246401, Madrid, Not set

Hospital Universitario de Salamanca /ID# 262218, Salamanca, Not set

Hospital Universitario y Politecnico La Fe /ID# 261625, Valencia, Not set

Helsingborgs Lasarett /ID# 262513, Helsingborg, Skane Lan

Uddevalla sjukhus /ID# 262034, Uddevalla, Vastra Gotalands Lan

Falu Lasarett /ID# 262231, Falun, Not set

National Taiwan University Hospital /ID# 245482, Taipei City, Taipei

China Medical University Hospital /ID# 245483, Taichung, Not set

Taichung Veterans General Hospital /ID# 261142, Taichung, Not set

Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastirma Hastanesi /ID# 261672, Ankara, Not set

Antalya Egitim Ve Arastirma Hastanesi /ID# 261674, Antalya, Not set

Trakya University Medical Facu /ID# 261673, Edirne, Istanbul, Not set

Istanbul Florence Nightingale Hospital /ID# 271543, Şişli, Not set

Addenbrooke's Hospital /ID# 261104, Cambridge, Cambridgeshire

Western General Hospital - NHS Lothian /ID# 261106, Edinburgh, Edinburgh, City Of

Dup_Guys and St Thomas NHS Foundation Trust - Guy's Hospital /ID# 262488, London, Greater London

Nottingham City Hospital /ID# 261105, Nottingham, Nottinghamshire

Leeds Teaching Hospitals NHS Trust /ID# 261101, Leeds, West Yorkshire

The Royal Marsden NHS Foundation Trust /ID# 262470, London, Not set

The Christie Hospital /ID# 261102, Manchester, Not set

Conditions: Multiple Myeloma

Learn More ›

Study With Elranatamab Versus Lenalidomide in Patients With Newly Diagnosed Multiple Myeloma After Transplant

NCT05317416

Recruiting

The purpose of this study is to evaluate whether elranatamab monotherapy can provide clinical benefit compared to lenalidomide monotherapy (control) in participants with newly diagnosed multiple myeloma after undergoing autologous stem cell transplant. In Part 1 and Part 2 of the study, participants in the study will either receive elranatamab (arm A and C) as an injection under the skin at the study clinic or lenalidomide orally once daily at home (arm B). Participation in the study will be app... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/13/2025

Locations: Banner Gateway Medical Center, Gilbert, Arizona +219 locations

Banner Gateway Medical Center, Gilbert, Arizona

Banner Gateway Medical Pavilion, Gilbert, Arizona

Banner MD Anderson Cancer Center, Gilbert, Arizona

Ronald Reagan UCLA Medical Center, Los Angeles, California

UCLA Hematology/Oncology - Westwood (Building 200 Suite 120), Los Angeles, California

UCLA Hematology/Oncology - Santa Monica, Los Angeles, California

Georgetown University Medical Center, Washington, District of Columbia

Miami Cancer Institute at Baptist Health, Inc., Miami, Florida

Emory University Hospital Midtown, Atlanta, Georgia

Emory University Hospital, Atlanta, Georgia

Investigational Drug Service, Emory University Clinic, Atlanta, Georgia

Winship Cancer Institute, Emory University, Atlanta, Georgia

Loyola University Chicago, Maywood, Illinois

Ascentist Doctor Hospital, Leawood, Kansas

American Oncology Partners, P.A. dba MidAmerica Cancer Care, Merriam, Kansas

O'Brien Pharmacy, Mission, Kansas

University of Michigan, Ann Arbor, Michigan

University Of Mississippi Medical Center, Jackson, Mississippi

University of Mississippi Medical Center, Jackson, Mississippi

American Oncology Partners, P.A. Dba MidAmerica Cancer Care, Kansas City, Missouri

Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

WMCHealth Advanced Physician Services, Hawthorne, New York

Westchester Medical Center, Valhalla, New York

Cleveland Clinic, Cleveland, Ohio

OhioHealth Arthur G.H. Bing, MD, Cancer Center, Columbus, Ohio

OhioHealth Research Institute, Columbus, Ohio

OhioHealth Riverside Methodist Hospital, Columbus, Ohio

Baylor University Medical Center, Dallas, Texas

Baylor Scott & White Medical Center - Temple, Temple, Texas

Royal Prince Alfred Hospital, Camperdown, New South Wales

Shoalhaven District Memorial Hospital, Nowra, New South Wales

Westmead Hospital, Westmead, New South Wales

Wollongong Hospital, Wollongong, New South Wales

Pindara Private Hospital, Benowa, Queensland

QScan Radiology Clinics, Clayfield, Queensland

Princess Alexandra Hospital, Woolloongabba, Queensland

Epworth Healthcare, East Melbourne, Victoria

Precision Haematology, East Melbourne, Victoria

St Vincent's Hospital (Melbourne), Fitzroy, Victoria

Slade Pharmacy, Richmond, Not set

Medizinische Universität Wien, Vienna, Wien

Hanusch-Krankenhaus, Vienna, Not set

Medizinische Universität Wien, Wien, Not set

Institut Jules Bordet, Anderlecht, Bruxelles-capitale, Région DE

Grand Hôpital de Charleroi, Charleroi, Hainaut

Université Catholique de Louvain-Namur - Centre Hospitalier Universitaire Dinant-Godinne - Site Godi, Yvoir, Namur

UZ Gent, Gent, Oost-vlaanderen

ZNA Middelheim, Antwerpen, Not set

Zna Cadix, Antwerpen, Not set

UZ Brussel, Brussel, Not set

Instituto D'Or de Pesquisa e Ensino (IDOR) - Filial Salvador, Salvador, Bahia

Centro Gaucho Integrado De Oncologia, Hematologia, Ensino E Pesquisa, Porto Alegre, RIO Grande DO SUL

Centro de Pesquisa Clínica - Área Administrativa, Porto Alegre, RIO Grande DO SUL

Hospital Mae de Deus, Porto Alegre, RIO Grande DO SUL

Hospital Amaral Carvalho, Jaú, SÃO Paulo

Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP), Ribeirão Preto, SÃO Paulo

BP - A Beneficencia Portuguesa de São Paulo, Sao Paulo, SÃO Paulo

Clínica Médica São Germano LTDA, SP, SÃO Paulo

Fundação Doutor Amaral Carvalho, Jaú, Not set

Américas Medical City, Rio de Janeiro, Not set

Instituto de Educação, Pesquisa e Gestão em Saúde, Rio de Janeiro, Not set

ESHO Empresa de Serviços Hospitalares S.A/ Hospital Samaritano de Higienópolis, São Paulo, Not set

HU UNIFESP / SPDM - Hospital São Paulo, São Paulo, Not set

Universidade Federal de Sao Paulo, São Paulo, Not set

Hospital Japonês Santa Cruz, São Paulo, Not set

Clínica Médica São Germano S/S Ltda, São Paulo, Not set

Arthur J.E. Child Comprehensive Cancer Centre, Calgary, Alberta

Dr. Everett Chalmers Regional Hospital, Fredericton, New Brunswick

Saint John Regional Hospital, Saint John, New Brunswick

Hamilton Health Sciences Corporation, Hamilton, Ontario

Princess Margaret Cancer Centre, Toronto, Ontario

Windsor Regional Hospital Cancer Program, Windsor, Ontario

Centre Integre Universitaire de la Santé et de Services Sociaux de l'Est-de-l'ile-de-Montreal,, Montreal, Quebec

McGill University Health Centre, Montreal, Quebec

Centre intégré universitaire de santé et de services sociaux du Nord-de-l'Île-de-Montréal (CIUSSS NÎ, Montreal, Quebec

Sun Yat-sen University Cancer Center, Guangzhou, Guangdong

Institute of hematology&blood disease hospital, Tianjin, Tianjin

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang

Fakultní nemocnice Brno Bohunice, Brno, Brno-město

Fakultni nemocnice Hradec Kralove, Hradec Kralove, Hradec Králové

Fakultni nemocnice Ostrava, Ostrava, Moravskoslezský KRAJ

Fakultni nemocnice Olomouc, Olomouc, Not set

Vseobecna fakultni nemocnice v Praze, Praha 2, Not set

Oulun yliopistollinen sairaala, Oulu, Pohjois-pohjanmaa

Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus), Helsinki, Uusimaa

Turku University Hospital, Turku, Varsinais-suomi

Institut Universitaire du Cancer Toulouse - Oncopole - CHU de TOULOUSE, Toulouse, Haute-garonne

Pitie Salpetriere University Hospital, Paris, Orne

Centre Hospitalier Universitaire de Poitiers, Poitiers, Vienne

Chu Grenoble Alpes, La Tronche, Not set

Hopital Claude Huriez - CHU de Lille, Lille, Not set

Hôpital Saint Antoine, Paris Cedex 12, Not set

Hopital Lyon Sud, Pierre Benite, Not set

Centre Hospitalier Régional Universitaire de Tours - Hôpital Bretonneau, Tours, Not set

Universitätsklinikum Würzburg, Würzburg, Bayern

Universitätsmedizin Johannes Gutenberg Universität Mainz, Mainz, Rheinland-pfalz

Universitätsklinikum Leipzig, Leipzig, Sachsen

Universitaetsklinikum Schleswig-Holstein Campus Kiel, Kiel, Schleswig-holstein

Charite Universitätsmedizin Berlin Campus Benjamin Franklin, Berlin, Not set

Klinikum Chemnitz gGMbH, Chemnitz, Not set

Universitätsklinikum Essen, Essen, Not set

Klinikum rechts der Isar der Technischen Universität München, München, Not set

Alexandra General Hospital of Athens, Athens, Attikí

Theageneio Cancer Hospital of Thessaloniki, Thessaloniki, Kentrikí Makedonía

University Hospital of Ioannina, Ioannina, Ípeiros

Somogy Megyei Kaposi Mór Oktató Kórház, Kaposvár, Somogy

Semmelweis University, Budapest, Not set

Dél-Pesti Centrumkórház, Budapest, Not set

Debreceni Egyetem Klinikai Kozpont, Debrecen, Not set

Szabolcs-Szatmár-Bereg Megyei Kórházak és Egyetemi Oktatókórház, Jósa András Oktatókórház, Nyíregyháza, Not set

Artemis hospital, Gurugram, Haryana

Medanta-The Medicity, Gurugram, Haryana

Fortis Memorial Research Institute, Gurugram, Haryana

Himalayan Institute Hospital Trust University, Dehradun, Uttarakhand

Tata Medical Center, Kolkata, WEST Bengal

Rajiv Gandhi Cancer Institute And Research Centre, Delhi, Not set

Soroka Medical Center, Be'er Sheva, Hadarom

Rabin Medical Center, Petah-Tikva, Hamerkaz

Sheba Medical Center, Ramat Gan, Hamerkaz

Rambam Health Care Campus, Haifa, Hatsafon

Tel-Aviv Sourasky Medical Center Dana-Dwek Children's Hospital, Tel Aviv, Tell Abīb

Shaare Zedek Medical Center, Jerusalem, Yerushalayim

Hadassah Medical Center, Jerusalem, Yerushalayim

Hadassah Mount Scopus Medical Center, Jerusalem, Yerushalayim

Shaare Zedek Medical Center, Jerusalem, Not set

IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Emilia-romagna

Fondazione Policlinico Universitario Agostino Gemelli, Roma, Lazio

Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Lombardia

Policlinico "G. Rodolico", Catania, Sicilia

Azienda Ospedaliero Universitaria Senese, Siena, Toscana

Azienda Ospedaliero Universitaria Ospedali Riuniti Umberto I - G.M. Lancisi - G. Salesi, Ancona, Not set

IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola, Bologna, Not set

AOU Policlinico Umberto I, Roma, Not set

Nagoya City University Hospital, Nagoya, Aichi

Gunma University Hospital, Maebashi, Gunma

Kobe City Medical Center General Hospital, Kobe-city, Hyogo

Iwate Medical University Hospital, Yahaba-cho, Iwate

University Hospital,Kyoto Prefectural University of Medicine, Kyoto-shi, Kyoto

Tohoku University Hospital, Sendai, Miyagi

Hamamatsu University Hospital, Hamamatsu-shi, Shizuoka

Shizuoka Cancer Center, Sunto-gun, Shizuoka

Nippon Medical School Hospital, Bunkyo-ku, Tokyo

Kagoshima University Hospital, Kagoshima, Not set

National Hospital Organization Kumamoto Medical Center, Kumamoto, Not set

University Hospital,Kyoto Prefectural University of Medicine, Kyoto, Not set

National Hospital Organization Okayama Medical Center, Okayama, Not set

Osaka Metropolitan University Hospital, Osaka, Not set

Japanese Red Cross Medical Center, Tokyo, Not set

Yamagata University Hospital, Yamagata, Not set

Gachon University Gil Medical Center, Namdong-gu, Incheon-gwangyeoksi [incheon]

Chonnam National University Hwasun Hospital, Hwasun Gun, Jeonranamdo

Seoul National University Bundang Hospital, Seongnam, Kyǒnggi-do

Pusan National University Hospital, Busan, Pusan-kwangyǒkshi

Seoul National University Hospital, Seoul, Seoul-teukbyeolsi [seoul]

Samsung Medical Center, Seoul, Seoul-teukbyeolsi [seoul]

The Catholic Univ. of Korea Seoul St. Mary's Hospital(Seoul St. Mary's Hospital), Seoul, Seoul-teukbyeolsi [seoul]

The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul, Seoul-teukbyeolsi [seoul]

Kyungpook National University, Daegu, Taegu-kwangyǒkshi

Kyungpook National University Hospital, Jung-gu, Taegu-kwangyǒkshi

HagaZiekenhuis, Den Haag, Zuid-holland

Maastricht Universitair Medisch Centrum, Maastricht, Not set

Isala, Zwolle, Not set

Oslo Universitetssykehus Ullevål, Oslo, Not set

Stavanger Universitetssykehus, Stavanger, Not set

Centrum Medyczne Pratia Poznań, Skorzewo, Wielkopolskie

Uniwersyteckie Centrum Kliniczne,, Gdansk, Not set

Uniwersytecki Szpital Kliniczny w Poznaniu, Poznan, Not set

Uniwersyteckie Centrum Kliniczne WUM Centralny Szpital Kliniczny, Warszawa, Not set

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy, Warszawa, Not set

Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu, Wroclaw, Not set

Pratia Onkologia Katowice, Katowice, Śląskie

Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, A Coruna

Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [barcelona]

Institut Català d'Oncologia - L'Hospitalet, L'Hospitalet Del Llobregat, Barcelona [barcelona]

Hospital Universitari Mutua Terrassa, Terrassa, Barcelona [barcelona]

Institut Catala d' Oncologia. Hospital Germans Trias i Pujol, Badalona, Barcelona

Hospital Universitari Mutua Terrassa, Terrassa, Barcelona

Hospital Universitario de Salamanca, Salamanca, Castilla Y LEÓN

Hospital Clínic de Barcelona, Barcelona, Catalunya [cataluña]

Clinica Universidad de Navarra, Madrid, Madrid, Comunidad DE

Hospital Universitario La Paz, Madrid, Madrid, Comunidad DE

Hospital Universitario Quironsalud Madrid, Pozuelo de Alarcon, Madrid

Hospital San Pedro de Alcántara, Cáceres, Not set

Institut Catala Oncologia - Hospital Universitari de Girona Dr Josep Trueta, Gerona, Not set

Hospital La Princesa, Madrid, Not set

Hospital General Universitario Gregorio Marañon, Madrid, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Hospital Universitario HM Sanchinarro, Madrid, Not set

Hospital Universitario de Salamanca - Complejo Asistencial Universitario de Salamanca, Salamanca, Not set

Hospital Universitari i Politecnic La Fe, València, Not set

Helsingborgs Lasarett, Helsingborg, Skåne LÄN [se-12]

Karolinska Universitetssjukhuset Huddinge, Stockholm, Stockholms LÄN [se-01]

Södra Älvsborgs Sjukhus Borås, Borås, Västra Götalands LÄN [se-14]

Falu Lasarett, Falun, Not set

Universitetssjukhuset Örebro, Örebro, Örebro LÄN [se-18]

Universitetssjukhuset i Linköping, Linköping, Östergötlands LÄN [se-05]

CHUV (centre hospitalier universitaire vaudois), Lausanne, Vaud

UniversitätsSpital Zürich, Zürich, Zürich (DE)

Kantonsspital Baden, Baden, Not set

Inselspital Bern, Berne, Not set

Kantonsspital Winterthur, Winterthur, Not set

China Medical University Hospital, Taichung, Not set

National Taiwan University Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Chang Gung Medical Foundation-Linkou Branch, Taoyuan, Not set

Medipol Mega Universite Hastanesi, İstanbul, İ̇stanbul

Sisli Florence Nightingale Hastanesi, İstanbul, İ̇stanbul

Ege Universitesi Hastanesi, Izmir, İ̇zmir

Dokuz Eylul Universitesi Hastanesi, İzmir, İ̇zmir

Ankara University Health Practice and Research Hospitals, Ankara, Not set

Dr. Abdurrahman Yurtaslan Ankara Onkoloji Egitim ve Arastırma Hastanesi, Ankara, Not set

Aydın Adnan Menderes Universitesi Hastanesi, Aydin, Not set

Erciyes Universitesi Tıp Fakultesi Hastaneleri, Kayseri, Not set

Özel Anadolu Sağlık Merkezi, Kocaeli, Not set

Addenbrooke's Hospital, Cambridge, Cambridgeshire

Queen Elizabeth Hospital Birmingham, Birmingham, England

Belfast City Hospital, Belfast, Not set

The Beatson West of Scotland Cancer Centre, Glasgow, Not set

Royal Berkshire Hospital, Reading, Not set

New Cross Hospital, Wolverhampton, Not set

Conditions: Multiple Myeloma

Learn More ›

Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

NCT05243797

Recruiting

This is a multicenter, randomized, open-label, Phase 3 study in participants with newly diagnosed multiple myeloma to evaluate the benefits of teclistamab in combination with lenalidomide and teclistamab alone versus lenalidomide alone as maintenance therapy after autologous stem cell transplant.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/13/2025

Locations: The University of Arizona Cancer Center, Phoenix, Arizona +207 locations

The University of Arizona Cancer Center, Phoenix, Arizona

University of California-Davis Cancer Center, Sacramento, California

University of California, San Diego (UCSD) Medical Center, San Diego, California

University of Colorado Hospital, Aurora, Colorado

Colorado Blood Cancer Institute, Denver, Colorado

Yale New Haven Hospital, New Haven, Connecticut

Christiana Care, Newark, Delaware

Blood & Marrow Transplant Center, Florida Hospital Medical Group, Orlando, Florida

Moffitt at Memorial Healthcare System, Tampa, Florida

University of Illinois Medical Center at Chicago, Chicago, Illinois

Greenebaum Cancer Center UM of MD, Baltimore, Maryland

John Hopkins, Baltimore, Maryland

Tufts Medical Center, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Montefiore Medical Cente, Bronx, New York

Mount Sinai Medical Center - 2, New York, New York

Levine Cancer Institute, Charlotte, North Carolina

Duke University, Durham, North Carolina

East Carolina University, Greenville, North Carolina

University of Cincinnati, Cincinnati, Ohio

Seidman Cancer Center-University Hospitals Cleveland Medical Center, Cleveland, Ohio

Ohio State Medical Center, James Cancer Center, Columbus, Ohio

Lehigh Valley Health Network, Allentown, Pennsylvania

Penn State Hershey Medical Center, Hershey, Pennsylvania

Abramson Cancer Center University of Pennsylvania Medical Center, Philadelphia, Pennsylvania

Fox Chase Cancer Center, Philadelphia, Pennsylvania

Medical University of South Carolina (MUSC), Charleston, South Carolina

Gibbs Cancer Center, Spartanburg, South Carolina

Vanderbilt University, Nashville, Tennessee

Baylor College of Medicine Center for Cell and Gene Therapy, Houston, Texas

LDS Hospital/ Intermountain Healthcare, Salt Lake City, Utah

Virginia Oncology Associates, Norfolk, Virginia

St Vincent HSHS (Green Bay Oncology), Green Bay, Wisconsin

University of Wisconsin Hospital and Clinics, Madison, Wisconsin

Froedtert Memorial Lutheran Hospital, Milwaukee, Wisconsin

Hospital Italiano, Buenos Aires, Not set

Hospital Privado, Córdoba, Not set

Sanatorio Britanico Rosario, Rosario, Not set

Sunshine Coast Health, Birtinya, Queensland

Flinders Medical Centre, Adelaide, Not set

Townsville University Hospital, Douglas, Not set

Barwon Health University Hospital Geelong Andrew Love Cancer Centre, Geelong, Not set

Alfred Hospital, Melbourne, Not set

Austin Health, Melbourne, Not set

Calvary Mater Hospital, Newcastle, Not set

Sunshine Coast Health, Sunshine Coast, Not set

Concord Repatriation General Hospital, Sydney, Not set

Royal North Shore Hospital, Sydney, Not set

Landeskrankenhaus, Feldkirch, Feldkirch, Not set

Medizinische Universitaet Innsbruck, Innsbruck, Not set

University Hospital Krems/Donau, Krems, Not set

Kepler Universitätsklinikum Med Campus III, Linz, Not set

Ordensklinikum Linz GmbH, Linz, Not set

Uniklinikum Salzburg, Salzburg, Not set

Clinic Ottakring, Vienna, Not set

LKH Hochsteiermark, Vienna, Not set

Jessa Ziekenhuis, Hasselt, Not set

Department of Hematology, CH Jolimont, La Louvière, Not set

Algemeen Ziekenhuis Delta, Leuven, Not set

University Hospital Leuven, Leuven, Not set

Centre hospitalier universitaire de Liege, Liège, Not set

Hospital Mãe de Deus - Centro Integrado de Oncologia, Porto Alegre, Not set

Hospital Santa Rita, Porto Alegre, Not set

Instituto Americas de Ensino,Pesquisa e Inovação, Rio de Janeiro, Not set

IDOR- Instituto D'or de pesquisa. Av. São Rafael, Salvador, Not set

A Real e Benemérita Associação Portuguesa de Beneficência, São Paulo, Not set

Clínica Medica São Germano,Grupo Oncoclínicas Pesquisa Clínica, São Paulo, Not set

Departamento de Oncologia Clínica AC Camargo Cancer Center, São Paulo, Not set

Grupo Oncoclínicas Pesquisa Clínica, São Paulo, Not set

Hcor, Associacao Siria, São Paulo, Not set

Hemocentro UNICAMP, Universidade Estadual de Campinas, São Paulo, Not set

Hospital das Clínicas da Universidade de São Paulo, São Paulo, Not set

Hospital Paulistano, Centro de Pesquisa Clinica R. Martiniano de Carvalho, São Paulo, Not set

Onco Star, São Paulo, Not set

Universidade Federal de São Paulo - Hospital São Paulo, São Paulo, Not set

Cross Cancer Institute, Edmonton, Not set

QEII Health Sciences Centre, Halifax, Not set

The Ottawa General Hospital, Ottawa, Not set

Saskatoon Cancer Center, Saskatoon, Not set

"Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Universitaire de Sherbrooke (CIUSSS de l'Estrie - CHUS)", Sherbrooke, Not set

Princess Margaret Cancer Centre, Toronto, Not set

BC Cancer, Vancouver, Not set

Beijing Chaoyang Hospital, Beijing, Not set

Peking University First Hospital, Beijing, Not set

North China University of Science and Technology Affiliated Hospital.Hematology Department, Hebei, Not set

Henan Cancer Hospital, Henan, Not set

Shandong Qilu Hospital, Shandong, Not set

Shanghai Fourth People's Hospital, Shanghai, Not set

Shenyang City, Liaoning Province, Hematology department, Shenyang, Not set

Institute of Hematology & Blood Disease Hospital Chinese Academy of Medical Science, Tianjin, Not set

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Not set

Tongji Hospital, Tongji Medical College of Hust, Wuhan, Not set

The First Affiliated Hospital, Zhejiang University College of Medicine, Zhejiang, Not set

Fakultni Nemocnice Hradec Kralove, Hradec Králové, Not set

University Hospital Olomouc, Olomouc, Not set

Fakultni Nemocnice Ostrava, Ostrava, Not set

Fakultni Nemocnice Plzen, Plzen, Not set

Vseobecna Fakultni Nemocnice V Praze, Praha, Not set

Aarhus Universitetshospital, Aarhus, Not set

Rigshospitalet, Copenhagen, Not set

Odense University Hospital, Odense, Not set

Lillebaelt Hospital, Vejle, Not set

Centre Hospitalier Universitaire De Bordeaux, Bordeaux, Not set

Department of Hematology, CHU Lille, Lille, Not set

Institut Paoli Calmettes, Marseille, Not set

Centre Hospitalier Universitaire De Montpellier, Montpellier, Not set

Centre Hospitalier Universitaire De Nantes, Nantes, Not set

Hopital Saint Louis, Paris, Not set

Hôpital Saint-Antoine, Paris, Not set

Centre Hospitalier Universitaire De Poitiers, Poitiers, Not set

Centre Hospitalier Universitaire De Toulouse, Toulouse, Not set

University Medical Center Hamburg-Eppendorf, Hamburg, Not set

Universitaetsklinikum Heidelberg AöR, Heidelberg, Not set

Universitaetsklinikum Jena KöR, Jena, Not set

Universitaetsklinikum Schleswig-Holstein AöR, Lübeck, Not set

Klinikum rechts der Isar der TU Muenchen AöR, München, Not set

Klinikum Nuernberg, Nürnberg, Not set

Universitaetsklinikum Tuebingen AöR, Tübingen, Not set

University Hospital of Würzburg, Würzburg, Not set

University General Hospital Of Alexandroupoli, Alexandroupolis, Not set

Evaggelismos Hospital, Athens, Not set

Regional General Hospital Alexandra, Athens, Not set

Theageneio Cancer Hospital, Thessaloníki, Not set

Cork University Hospital, Cork, Not set

Beaumont Hospital, Dublin, Not set

St James's Hospital, Dublin, Not set

St Vincent's University Hospital, Dublin, Not set

University Hospital Galway, Galway, Not set

University Hospital Limerick, Limerick, Not set

The Barzilai Medical Center, Be'er Sheva, Not set

Health Care Campus, Haifa, Not set

Hadassah Medical Center, Jerusalem, Not set

Beilinson Hospital, Petah tikva, Not set

Chaim Sheba Medical Center, Ramat Gan, Not set

Tel-Aviv Sourasky Medical Center, Tel Aviv, Not set

Azienda Sanitaria Locale Al Di Alessandria, Alessandria, Not set

Azienda Ospedaliero Universitaria Ospedali Riuniti Umberto I G M Lancisi G Salesi, Ancona, Not set

AOU G. Baccelli, Bari, Not set

Policlinico di Bari, Bari, Not set

A.O. Papa Giovanni XXIII, Bergamo, Not set

A.O.U. di Bologna - Policlinico S. Orsola Malpighi, Bologna, Not set

A.O.Spedali Civili di Brescia, Brescia, Not set

Ospedale Oncologico 'A. Businco', Cagliari, Not set

Azienda Ospedaliera-Universitaria Di Cosenza, Cosenza, Not set

Careggi University Hospital, Firenze, Not set

IRCCS Ospedale Policlinico San Martino, Genova, Not set

IRCCS Ospedale Maggiore Policlinico, Milano, Not set

Azienda Ospedaliero Universitaria Di Modena, Modena, Not set

Azienda Ospedaliera Di Rilievo Nazionale Antonio Cardarelli, Napoli, Not set

UOC Oncoematologia, Ospedale Policlinico Federico II, Napoli, Not set

Azienda Ospedaliero-Universitaria Maggiore Della Carita, Novara, Not set

UOC Ematologia - Azienda Ospedale - Università Padova Ospedale Giustinianeo, Padova, Not set

Department of Hematology and Bone Marrow Transplant Centre, Azienda Ospedaliero - Universitaria di Parma, Parma, Not set

Fondazione IRCCS Policlinico San Matteo, Pavia, Not set

Azienda Sanitaria Locale Di Pescara, Pescara, Not set

Ospedale Santa Maria delle Croci, Ravenna, Not set

Azienda USL IRCCS Di Reggio Emilia, Reggio, Not set

Ospedale "Infermi" di Rimini, Rimini, Not set

Ematologia, Azienda Policlinico Umberto I, Roma, Not set

Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Not set

A.O.U. Città della Salute e della Scienza di Torino - SC Ematologia U, Torino, Not set

A.O.U. Ospedali Riuniti di Trieste, Trieste, Not set

Azienda Sanitaria Universitaria Friuli Centrale, Udine, Not set

Chonnam National University Hwasun Hospital, Gwangju, Not set

Department of Oncology, Asan Medical Center, Seoul, Not set

Samsung Medical Center, Seoul, Not set

Seoul National University Hospital, Internal Medicine, Seoul, Not set

Severance Hospital, Seoul, Not set

St. Mary's Hospital, Seoul, Not set

Noordwest Ziekenhuisgroep Stichting, Alkmaar, Not set

Amsterdam University Medical Center, Amsterdam, Not set

Albert Schweitzer Ziekenhuis, Dordrecht, Not set

Maxima Medisch Centrum, Eindhoven, Not set

University Medical Center Groningen, Groningen, Not set

Dijklander Ziekenhuis, Hoorn, Not set

St. Antonius Ziekenhuis, Nieuwegein, Not set

Erasmus University Medical Center Rotterdam, Rotterdam, Not set

Maasstad Ziekenhuis, Rotterdam, Not set

Oslo University Hospital, Oslo, Not set

St. Olavs hospital HF, Trondheim, Not set

Department of Hematology and Transplantology University Clinical Center, Gdańsk, Not set

SPZOZ MSWiA w Poznaniu im. Prof. Ludwika Bierkowskiego, Poznań, Poznań, Not set

Uniwersytecki Szpital Kliniczny, Wrocław, Not set

CCAB Centro Clinico Academico Braga Associacao, Braga, Not set

Champalimaud Clinical Centre, Lisboa, Not set

Instituto Portugues De Oncologia De Lisboa Francisco Gentil E.P.E., Lisboa, Not set

Instituto Portugues De Oncologia Do Porto Francisco Gentil E.P.E., Porto, Not set

Sao Joao University Hospital Center, Porto, Not set

Unidade Local De Saude De Gaia/Espinho E.P.E., Porto, Not set

Unidade Local De Saude De Tras-Os-Montes E Alto Douro E.P.E., Vila Real, Not set

University Clinical Center of Serbia, Belgrade, Not set

Clinical Centre of Kragujevac, Kragujevac, Not set

Clinical Centre of Nis, Niš, Not set

Clinical Centre of Vojvodina, Novi Sad, Not set

University Hospital Basel, Basel, Not set

Inselspital, Bern, Not set

Kantonsspital St. Gallen, Saint Gallen, Not set

Ankara Liv Hospital, Ankara, Not set

Ankara University Hospital, Ankara, Not set

Florence Nightingale Hospital, Istanbul, Not set

Medipol Mega University Hospital, Istanbul, Not set

Ege University Medical faculty Hospital Internal Medicine Department Adult Hematology Unit, İzmir, Not set

Izmir Economy University, Medical Point Hospital, İzmir, Not set

Erciyes University Hospital, Kayseri, Not set

Hammersmith Hospital - Imperial College NHS Healthcare Trust, London, Not set

University College London (UCL), London, Not set

The Royal Marsden Hospital, Sutton, Not set

Conditions: Multiple Myeloma

Learn More ›

Collection of Tissue Samples for Cancer Research

NCT00900198

Recruiting

Background: -Patients who are being evaluated and/or treated at the NIH Clinical Center and adult patients at participating sites will be entered onto this tissue procurement protocol for collection of tissue specimens. Objectives: * To obtain samples from adult and pediatric patients for research purposes from tests and procedures that are done as required by the primary research protocol(s) to which a patient is enrolled or as part of their standard-of-care treatment. * To obtain samples for research purposes from non-surgical procedures, such as percutaneous biopsies, performed for the sole purpose of obtaining tissue specimens or biological fluids for this protocol. Eligibility: -Adult patients (18 years of age and older) and pediatric patients (younger than 18 years of age) who are being evaluated for and/or treated for cancer at the NIH Clinical Center participating sites. Design: * This is a multicenter tissue procurement protocol with NCI as the coordinating center. * For adult patients: specimens for research purposes, as outlined in this protocol, will be obtained from tests and procedures that are done as required by the primary research protocols to which a patient is enrolled or as part of their standard-of-care treatment. Non-surgical procedures, such as percutaneous biopsies, may also be performed for the sole purpose of obtaining tissue specimens or biological fluids for this protocol. Tissues and biological fluids to be procured may include but are not limited to blood, serum, urine, tumor tissue, normal tissue, pleural fluid, CSF, saliva, bronchial alveolar lavage (BAL), circulating tumor cells, hair follicles, and bone marrow. These specimens will be stored with unique identifiers and used to perform only those research studies that are outlined in this protocol. * For pediatric patients: tumor biopsy/resection tissue used for pediatric preclinical model development will only be from tissue already being obtained as part of a procedure necessary for the patient s clinical care or as part of a primary research protocol; blood specimens will be collected as part of a blood collection already scheduled for the patient s clinical care or as part of the planned pre-procedure bloodwork; volumes collected will not exceed institutional research limits. * Given the risks associated with any invasive procedure, such as tumor biopsy, the procedure will be discussed in detail with the patients and their parents/guardian (as indicated), including the side effects, prior to obtaining a separate consent for each procedure. A separate consent will not be signed prior to obtaining samples by minimally invasive measures, such as venipuncture. * This study has two separate consent forms at the NIH Clinical Center: one for adult patients to donate specimens for ongoing research on assay development and studies of molecular pathways, and one for adult and age-appropriate pediatric patients to donate samples for the generation of preclinical models. The study also has consent form templates for adult and pediatric patients at participating sites to donate specimens to create preclinical models. * Patients may remain on study for the duration of their consent or completion of the planned procedure, whichever comes first. Read Less

Gender:

ALL

Ages:

2 months and above

Trial Updated:

08/13/2025

Locations: UC Davis, Sacramento, California +16 locations

Conditions: Neoplasms, Lymphomas, Multiple Myeloma, Myelodysplastic Syndrome

Learn More ›

Iberdomide Versus Observation Off Therapy After Idecabtagene Vicleucel CAR-T for Multiple Myeloma

NCT06179888

Recruiting

This phase II trial compares iberdomide maintenance therapy to disease monitoring for improving survival in patients who have received idecabtagene vicleucel (a type of chimeric antigen receptor T-cell \[CAR-T\] therapy) for multiple myeloma. The usual approach after treatment with idecabtagene vicleucel is to monitor the multiple myeloma without giving myeloma medications. There is currently no medication approved specifically for use after idecabtagene vicleucel treatment. Upon administration,... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/13/2025

Locations: Cedars Sinai Medical Center, Los Angeles, California +68 locations

Cedars Sinai Medical Center, Los Angeles, California

UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Augusta University Medical Center, Augusta, Georgia

University of Illinois, Chicago, Illinois

UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny, Iowa

UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive, Iowa

Iowa Methodist Medical Center, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa

Mercy Medical Center - Des Moines, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines, Iowa

Baptist Memorial Hospital and Cancer Center-Desoto, Southhaven, Mississippi

Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Siteman Cancer Center-South County, Saint Louis, Missouri

Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri

Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri

Nebraska Medicine-Bellevue, Bellevue, Nebraska

Nebraska Medicine-Village Pointe, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Memorial Sloan Kettering Monmouth, Middletown, New Jersey

Memorial Sloan Kettering Bergen, Montvale, New Jersey

Memorial Sloan Kettering Commack, Commack, New York

Memorial Sloan Kettering Westchester, Harrison, New York

Memorial Sloan Kettering Cancer Center, New York, New York

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Atrium Health Pineville/LCI-Pineville, Charlotte, North Carolina

Atrium Health University City/LCI-University, Charlotte, North Carolina

Atrium Health Cabarrus/LCI-Concord, Concord, North Carolina

Levine Cancer Institute - Huntersville, Huntersville, North Carolina

Atrium Health Union/LCI-Union, Monroe, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Sanford Roger Maris Cancer Center, Fargo, North Dakota

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Providence Portland Medical Center, Portland, Oregon

Providence Saint Vincent Medical Center, Portland, Oregon

Geisinger Medical Center, Danville, Pennsylvania

Prisma Health Cancer Institute - Eastside, Greenville, South Carolina

Baptist Memorial Hospital and Cancer Center-Memphis, Memphis, Tennessee

Houston Methodist San Jacinto Hospital, Baytown, Texas

Houston Methodist Cypress Hospital, Cypress, Texas

Houston Methodist Hospital, Houston, Texas

Methodist Willowbrook Hospital, Houston, Texas

Houston Methodist West Hospital, Houston, Texas

Houston Methodist Saint John Hospital, Nassau Bay, Texas

Houston Methodist Sugar Land Hospital, Sugar Land, Texas

Houston Methodist The Woodlands Hospital, The Woodlands, Texas

Swedish Cancer Institute-Edmonds, Edmonds, Washington

Swedish Cancer Institute-Issaquah, Issaquah, Washington

Swedish Medical Center-First Hill, Seattle, Washington

Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin

Aurora Saint Luke's South Shore, Cudahy, Wisconsin

Aurora Health Care Germantown Health Center, Germantown, Wisconsin

Aurora Cancer Care-Grafton, Grafton, Wisconsin

Aurora BayCare Medical Center, Green Bay, Wisconsin

Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin

Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin

Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin

Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin

Aurora Sinai Medical Center, Milwaukee, Wisconsin

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin

Aurora Cancer Care-Racine, Racine, Wisconsin

Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin

Aurora Medical Center in Summit, Summit, Wisconsin

Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin

Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin

Aurora West Allis Medical Center, West Allis, Wisconsin

Conditions: Multiple Myeloma

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A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)

NCT06215118

Recruiting

The main purpose of the study is to understand how safe and tolerable is elranatamab when given along with iberdomide. There are 2 parts to this study. Part 1 will look at how safe and tolerable is elranatamab when given with iberdomide. Part 2 will look at the correct amount of this combination that can be given to patients with relapsed or refractory multiple myeloma. Myeloma is a type of cancer that begins in plasma cells (white blood cells that produce antibodies). Refractory means a disea... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: Emory University Hospital Midtown, Atlanta, Georgia +34 locations

Emory University Hospital Midtown, Atlanta, Georgia

Emory University Hospital, Atlanta, Georgia

Winship Cancer Institute, Atlanta, Georgia

Indiana CTSI Clinical Research Center (ICRC), Indianapolis, Indiana

Indiana University Health University Hospital, Indianapolis, Indiana

Indiana University Melvin and Bren Simon Comprehensive Cancer Center (IUSCCC), Indianapolis, Indiana

University of Maryland, Baltimore, Maryland

Brigham and Women's Hospital, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

Dana-Farber Cancer Institute - Chestnut Hill, Newton, Massachusetts

University of Massachusetts Chan Medical School, Worcester, Massachusetts

Methodist Hospital, Omaha, Nebraska

Oncology Hematology West P.C. dba Nebraska Cancer - Methodist, Omaha, Nebraska

Oncology Hematology West P.C. dba Nebraska Cancer Specialists, Omaha, Nebraska

Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire

MSK Basking Ridge, Basking Ridge, New Jersey

MSK Monmouth, Middletown, New Jersey

MSK Bergen, Montvale, New Jersey

MSK Commack, Commack, New York

MSK Westchester, Harrison, New York

Memorial Sloan Kettering Cancer Center - Investigational Drug Service Pharmacy, Long Island City, New York

Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street)., New York, New York

Memorial Sloan Kettering Cancer Center - Main Campus, New York, New York

MSK Nassau, Uniondale, New York

Fred Hutchinson Cancer Center, Seattle, Washington

University of Washington, Seattle, Washington

Liverpool Hospital, Liverpool, New South Wales

Calvary Mater Newcastle, Waratah, New South Wales

Townsville University Hospital, Douglas, Queensland

Epworth Freemasons, East Melbourne, Victoria

Epworth Hospital, Richmond, Victoria

Slade Pharmacy, Richmond, Victoria

Dr. Everett Chalmers Regional Hospital, Fredericton, New Brunswick

CIUSSS de l'Est-de-l'Île-de-Montréal, Montreal, Quebec

Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Univer, Sherbrooke, Quebec

Conditions: Multiple Myeloma

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Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

NCT05092451

Recruiting

The goal of this clinical research study is to learn about the safety of giving immune cells called natural killer (NK) cells with chemotherapy to patients with leukemia, lymphoma, or multiple myeloma. Immune system cells (such as NK cells) are made by the body to attack foreign or cancerous cells. Researchers think that NK cells you receive from a donor may react against cancer cells in your body, which may help to control the disease.

Gender:

ALL

Ages:

Between 12 years and 80 years

Trial Updated:

08/12/2025

Locations: M D Anderson Cancer Center, Houston, Texas

Conditions: B-Cell Lymphoma, Myelodysplastic Syndromes (MDS), Acute Myeloid Leukemia (AML), Multiple Myeloma, Plasma Cell Leukemia, Hodgkin Lymphoma, T-cell Non-Hodgkin's Lymphoma/ T-cell Acute Lymphoblastic Leukmeia, Myelodysplastic Syndrome / Chronic Myelomonocytic Leukemia, Blastic Transformation of Chronic Myeloid Leukemia, Germ Cell Tumors

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Elranatamab Post Trial Access Study for Participants With Multiple Myeloma (MM)

NCT06057402

Recruiting

This is a post-trial access (PTA) open-label, single-arm study in Multiple Myeloma participants who continue to derive clinical benefit from elranatamab monotherapy in the Pfizer-sponsored elranatamab Parent Studies.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: UCHealth Poudre Valley Hospital, Fort Collins, Colorado +17 locations

Conditions: Multiple Myeloma

Learn More ›

Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma

NCT06207799

Recruiting

To learn if giving elranatamab before and after an autologous stem cell transplant (ASTC) can help to control newly diagnosed, high-risk MM. An ASTC is a type of transplant in which a person's own stem cells are collected, preserved, and returned to them.

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

08/12/2025

Locations: MD Anderson Cancer Center, Houston, Texas

Conditions: Multiple Myeloma, Post-transplant MRD-guided Maintenance Therapy, Pre-transplant Purging

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A Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab in People With Monoclonal Gammopathy of Renal Significance (MGRS)

NCT06083922

Recruiting

The purpose of this study is to find out whether cyclophosphamide, bortezomib, dexamethasone (CyBorD) with daratumumab SC is a safe treatment combination for MGRS-associated kidney disease including cast nephropathy associated with multiple myeloma. In addition, the researchers will find out whether the study drug combination is an effective treatment for these conditions.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/12/2025

Locations: Tufts Medical Center (Data Collection Only), Boston, Massachusetts +10 locations

Conditions: Multiple Myeloma, Monoclonal Gammopathy of Renal Significance

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Linvoseltamab in Addition to Lenalidomide (L2) During Maintenance Therapy of NDMM to Deepen Responses or Redrive MRD Negativity After Relapse

NCT06910124

Recruiting

The purpose of this study is to determine whether giving linvoseltamab with lenalidomide during maintenance treatment to participants with multiple myeloma will: 1. Get rid of any residual multiple myeloma cells in participants' bodies which is known as minimal residual disease negative (MRD-) status. For participants that start the study with residual multiple myeloma cells in participants' bodies: to determine how long you remain MRD-. 2. Increase the length of time that participants' disease... Read More

Gender:

ALL

Ages:

All

Trial Updated:

08/11/2025

Locations: University of Miami, Miami, Florida

Conditions: Multiple Myeloma

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A Study of Teclistamab and Mezigdomide in People With Multiple Myeloma

NCT07105059

Recruiting

The researchers are doing this study to find out whether combining teclistamab and mezigdomide is a safe and effective treatment approach in people with relapsed/refractory multiple myeloma (MM).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/11/2025

Locations: Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey +6 locations

Conditions: Multiple Myeloma

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