There are currently 28 active clinical trials seeking participants for Psychosis research studies. The states with the highest number of trials for Autism participants are California, Massachusetts, Ontario and New York.
Relationship Between Efficacy of Lumateperone and Brain Glutamate and Dopamine
NCT05890768
Recruiting
This study will examine the differential relationships between antipsychotic efficacy and changes in dopaminergic and glutamatergic brain metabolism in lumateperone and risperidone treated early psychosis patients. Baseline glutamate and dopamine brain scans, and symptom severity measures will be collected, followed by repeated measures at 6 weeks. Half of the early psychosis patients will be treated with lumateperone, half with risperidone. Healthy control subejcts will also be examined once.
Gender:
All
Ages:
Between 18 years and 40 years
Trial Updated:
05/25/2023
Locations: University of New Mexico, Albuquerque, New Mexico
Conditions: Psychosis
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Psychosis TMS Study
NCT05857137
Recruiting
The main goal of this study is to investigate the neural mechanisms of working memory function in patients with early psychosis using Transcranial Magnetic Stimulation (TMS) in conjunction with functional MRI. TMS is a noninvasive method used to modulate brain activity via changing magnetic fields applied over the surface of the scalp.
Gender:
All
Ages:
Between 18 years and 35 years
Trial Updated:
05/04/2023
Locations: Martinos Center for Biomedical Imaging, Charlestown, Massachusetts
Conditions: Psychosis
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Toward a Computationally-Informed, Personalized Treatment for Hallucinations
NCT04366518
Recruiting
Auditory hallucinations are among the most distressing aspects of psychotic illness, and between 10 and 30% of people with hallucinations do not respond to antipsychotic medications. The authors have used computational modeling of behavior to link brain activity to development of auditory hallucinations in the hope of guiding new treatment development. The proposed studies take the first step toward individualized treatment approaches to hallucinations by attempting causal, pharmacological manip... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/02/2023
Locations: Connecticut Mental Health Center, New Haven, Connecticut
Conditions: Hallucinations, Auditory, Psychosis
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Multiomic Diagnostics in Youth With Psychosis
NCT05457140
Recruiting
Rady Children's Institute for Genomic Medicine seeks to understand the genomes and immune systems in 15 children and adolescents who are admitted to Rady Children's Hospital Child and Adolescent Psychiatry Service with psychotic symptoms or schizophrenia. Cutting-edge genome and protein sequencing technology will be used to better understand how immunological and genetic assessments may improve our ability to identify the cause of psychosis and impact care. The investigator also hopes to identif... Read More
Gender:
All
Ages:
Between 7 years and 17 years
Trial Updated:
10/24/2022
Locations: Rady Children's Hospital San Diego, San Diego, California
Conditions: Psychosis
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