There are currently 32 active clinical trials seeking participants for Pulmonary Hypertension research studies. The states with the highest number of trials for Pulmonary Hypertension participants are California, Florida, New York and Ohio.
Pulmonary Hypertension in Left Heart Disease
NCT05935605
Recruiting
The goal is to compare patients with and without varying severity of pulmonary vascular disease based upon hemodynamic signatures, echocardiographic measures, and lung ultrasound, in tandem with expired gas metabolic testing and blood sampling.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/17/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Pulmonary Hypertension, Pulmonary Vascular Disease, Left Heart Disease
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Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System
NCT04555161
Recruiting
This prospective study is a multi-center early feasibility study assessing the safety and performance of the Aria CV Pulmonary Hypertension System in patients with pulmonary hypertension and right heart dysfunction.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/27/2025
Locations: University of California - San Diego, La Jolla, California +11 locations
Conditions: Pulmonary Arterial Hypertension, Pulmonary Hypertension, Right Heart Dysfunction
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Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure
NCT06299436
Recruiting
Right ventricular (RV) failure is recognized to worsen patient outcomes in the setting of heart failure with reduced ejection fraction (HFrEF)-related pulmonary hypertension (PH), yet the investigators fall short in trying to identify and treat it. The current proposal will (1) determine the best clinical indicators of intrinsic RV myocyte contractile failure in humans with HFrEF-PH, (2) clarify underlying mechanisms, and (3) test novel treatments on RV myocytes. The long-term goal of this propo... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
01/21/2025
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Heart Failure With Reduced Ejection Fraction, Pulmonary Hypertension, Right Heart Failure Due to Left Heart Failure
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Activity Monitoring in Pulmonary Hypertension
NCT04101630
Recruiting
This is a prospective, longitudinal, observational study of free-living activity trackers and patient reported outcomes to test the hypothesis that daily activity will have stronger prognostic value than 6MWD in patients with pulmonary hypertension after 12 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/16/2024
Locations: Vanderbilt University Medical Center, Nashville, Tennessee
Conditions: Pulmonary Hypertension
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Pulmonary Vascular Hemodynamics Before and After Mitral Valve Procedures
NCT04947384
Recruiting
The objective of this proposal is to study circulating and echocardiographic markers of pulmonary vascular and right ventricular remodeling in patients with a WHO-2 diagnosis of pulmonary hypertension after mitral valve procedures. The investigators are proposing the study will be impactful for the early detection and prediction and of residual pulmonary hypertension (PH) that would otherwise be undetected and fatal with no curative treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/27/2024
Locations: The University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Pulmonary Hypertension
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Identifying Right Ventricular Dysfunction in COPD Through Right Heart Catheterization, Imaging and Exercise
NCT05896579
Recruiting
This study plans to learn more about heart function among individuals with chronic obstructive pulmonary disease (COPD). In particular, the investigators want to understand the different patterns of right ventricular response to pulmonary hypertension (high pressure in the lungs) during rest and exercise. By identifying patterns of right ventricular dysfunction, this study will help identify better treatments for patients with COPD in the future.
Gender:
ALL
Ages:
Between 40 years and 80 years
Trial Updated:
08/05/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: COPD, Pulmonary Hypertension, Right Ventricular Dysfunction
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Evaluating Infrasonic Hemodynography
NCT04636892
Recruiting
This comparative diagnostic accuracy study will determine the accuracy of a noninvasive wearable infrasonic sensor to detect the mechanical, electrical, and hemodynamic function of the cardiovascular system.
Gender:
ALL
Ages:
All
Trial Updated:
04/15/2024
Locations: Scripps Health, La Jolla, California
Conditions: Aortic Stenosis, Mitral Regurgitation, Pulmonary Hypertension, Heart Failure, Systolic, Cardiovascular Diseases, Coronary Artery Disease
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New Orleans Pulmonary Hypertension Biobank
NCT03269630
Recruiting
Pulmonary hypertension (PH) is a serious condition characterized by a mean pulmonary artery pressure \>=25mmHg on right heart catheterization (RHC). Despite advances in PH care, outcomes are still sub-optimal and further research is required into the pathobiology of the disease and development of biomarkers that can guide clinical care. The investigators are establishing a biobank to collect samples (blood, urine, stool) from patients with pulmonary hypertension, patients at high risk for pulmon... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/09/2021
Locations: University Medical Center-New Orleans, New Orleans, Louisiana
Conditions: Pulmonary Hypertension, Systemic Sclerosis, Mixed Connective Tissue Disease, Heart Failure With Normal Ejection Fraction, Healthy
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