There are currently 17 active clinical trials seeking participants for Septic Shock research studies. The states with the highest number of trials for Septic Shock participants are Massachusetts, Ontario, Pennsylvania and Utah.
Machine Learning Sepsis Alert Notification Using Clinical Data
NCT04005001
Recruiting
Machine learning is a powerful method to create clinical decision support (CDS) tools, when training labels reflect the desired alert behavior. In our Phase I work for this project, we developed HindSight, an encoding software that was designed to examine discharged patients' electronic health records (EHRs), identify clinicians' sepsis treatment decisions and patient outcomes, and pass those labeled outcomes and treatment decisions to an online algorithm for retraining of our machine-learning-b... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/27/2022
Locations: Baystate Health, Springfield, Massachusetts +2 locations
Conditions: Sepsis, Severe Sepsis, Septic Shock
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LIPIDS-P Trial Phase I/II
NCT03405870
Recruiting
Briefly, this pilot clinical trial will evaluate preliminary safety and efficacy of the study drug (Smoflipid) at elevating cholesterol levels (primary outcome) in patients with sepsis and moderate organ dysfunction and will also evaluate measures of organ dysfunction, mortality, and biological activity (secondary outcomes).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/10/2022
Locations: Department of Emergency Medicine, UF Health Jax ICU/MICU, Jacksonville, Florida +2 locations
Conditions: Sepsis, Severe, Septic Shock
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A Trial of Vitamin B12 in Septic Shock
NCT03783091
Recruiting
This study will randomize 20 septic shock patients to receive either a single 5 gram dose of IV vitamin B12 (Cyanokit® Meridian Medical Technologies, Columbia, MD) versus placebo in addition to standard of care to test the feasibility of completing clinical and laboratory protocols.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/30/2021
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Septic Shock
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Function of Circulating Exosomes in Sepsis-induced Immunosuppression
NCT04979767
Recruiting
This is a single-center prospective bio-specimen analysis and observational study aiming to define immune pathways disrupted in bacterial sepsis and to identify clinically useful biomarkers of immune status.
Gender:
All
Ages:
50 years and above
Trial Updated:
07/16/2021
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Sepsis, Septic Shock, Sepsis Syndrome, Sepsis Bacterial, Sepsis, Severe, Sepsis Bacteremia
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De-resuscitation Informed by Ultrasound for Patients With Sepsis
NCT04921319
Recruiting
Randomized, unblinded clinical trial of 152 critically ill patients with sepsis admitted to the intensive care unit. The primary determine if using the Venous Excess Ultrasound Score (VExUS) to guide fluid deresuscitation in critically ill patients with sepsis reduces net fluid balance at 5 days as compared to usual care.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/02/2021
Locations: The Miriam Hospital, Providence, Rhode Island
Conditions: Sepsis, Septic Shock, Sepsis, Severe, Volume Overload
Register for Updates