There are currently 167 clinical trials in Boca Raton, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Boca Raton Regional Hospital, Parkinson's Disease and Movement Disorders Center of Boca Raton, GSK Investigational Site and Excel Medical Clinical Trials. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Recruiting
The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in children and adolescents.
Gender:
All
Ages:
Between 6 years and 17 years
Trial Updated:
06/17/2024
Locations: First Choice Neurlogy Espinosa Neuroscience Institute, Boca Raton, Florida
Conditions: Pediatric Migraine
A Phase 3 Study to Evaluate the Efficacy and Safety of Efgartigimod IV in Patients With Acetylcholine Receptor Binding Antibody Seronegative Generalized Myasthenia Gravis
Recruiting
The primary purpose of this study is to measure the efficacy and safety of efgartigimod intravenously (IV) compared to placebo in participants with Acetylcholine Receptor Binding Antibody (AChR-Ab) seronegative Generalized Myasthenia Gravis (gMG). Other objectives are to assess long-term efficacy, safety, and tolerability of efgartigimod. Study will consist of: Screening Part A: participants will be randomized to receive either efgartigimod IV or placebo Part B: participants completing part A... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: First Choice Neurology Boca Raton, Boca Raton, Florida +1 locations
Conditions: Generalized Myasthenia Gravis
A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.
Recruiting
CKJX839D12302 is a pivotal Phase III study designed to test the hypothesis that treatment with inclisiran sodium 300 milligram (mg) subcutaneous (s.c.) administered on Day 1, Day 90, and every 6 months thereafter in patients at high cardiovascular (CV) risk without a prior major atherosclerotic cardiovascular disease (ASCVD) event will significantly reduce the risk of 4-Point-Major Adverse Cardiovascular Events (4P-MACE) defined as a composite of CV death, non-fatal myocardial infarction (MI), n... Read More
Gender:
All
Ages:
Between 40 years and 79 years
Trial Updated:
06/17/2024
Locations: Excel Medical Clinical Trials LLC, Boca Raton, Florida
Conditions: Primary Prevention of Atherosclerotic Cardiovascular Disease
A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight
Recruiting
The purpose of this study is to is to evaluate the efficacy and safety of retatrutide in participants with type 2 diabetes in participants who have obesity or overweight (J1I-MC-GZBK master protocol) including a subset of participants who have obstructive sleep apnea (OSA) (J1I-MC-GSA2). The study will last about 89 weeks and will include up to 24 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: Excel Medical Clinical Trials, Boca Raton, Florida
Conditions: Type 2 Diabetes, Obesity, Overweight, Obstructive Sleep Apnea
ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation
Recruiting
This study is conducted to see if ziltivekimab reduces the risk of having cardiovascular events (for example heart attack and stroke) in people with cardiovascular disease, chronic kidney disease and inflammation. Participants will either get ziltivekimab (active medicine) or placebo (a dummy medicine which has no effect on the body). This is known as the study medicine. Which treatment participants get is decided by chance. Participants chance of getting ziltivekimab or placebo is the same. Z... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: Excel Med Ctr Clinical Trials, Boca Raton, Florida
Conditions: Cardiovascular Risk, Chronic Kidney Disease, Inflammation
A Donanemab (LY3002813) Prevention Study in Participants With Alzheimer's Disease (TRAILBLAZER-ALZ 3)
Recruiting
The main purpose of this study is to evaluate the safety and efficacy of donanemab in participants with preclinical Alzheimer's Disease (AD).
Gender:
All
Ages:
Between 65 years and 80 years
Trial Updated:
06/17/2024
Locations: Neurology Offices of South Florida, Boca Raton, Florida +2 locations
Conditions: Alzheimer Disease
A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus
Recruiting
The goal of this clinical trial is to see how well cenerimod reduces symptoms of Systemic Lupus Erythematosus in adult patients with moderate to severe symptoms. The main questions it aims to answer are: How well cenerimod works on top of the treatment already being administered. How safe cenerimod is for adult patients with Systemic Lupus Erythematosus. Researchers will compare one dose of cenerimod and a placebo to see how well cenerimod works when it is added to the treatment already being... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
06/17/2024
Locations: RASF-Clinical Research Inc., Boca Raton, Florida
Conditions: Lupus Erythematosus, Systemic
Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus
Recruiting
Systemic Lupus Erythematosus (SLE) is an immune-mediated disease associated with inflammation of multiple organ systems. This study will assess how safe and effective upadacitinib is in treating adult participants with moderately to severely active SLE. Adverse events and change in the disease activity will be assessed. Upadacitinib is an approved drug for rheumatoid arthritis, psoriatic arthritis, and axial spondylarthritis and is being developed for the treatment of SLE. This study is "double... Read More
Gender:
All
Ages:
Between 18 years and 63 years
Trial Updated:
06/14/2024
Locations: Rheumatology Associates of South Florida (RASF) - Clinical Research /ID# 253623, Boca Raton, Florida
Conditions: Systemic Lupus Erythematosus
Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic nOH in Participants With Multiple System Atrophy
Recruiting
This is a Phase 3, multi-center, randomized withdrawal study to evaluate the efficacy and durability of ampreloxetine in participants with MSA and symptomatic nOH after 20 weeks of treatment. This study includes 4 periods: Screening, open label, randomized withdrawal, and long-term treatment extension (LTE).
Gender:
All
Ages:
30 years and above
Trial Updated:
06/14/2024
Locations: Parkinson's Disease And Movement Disorders Center of Boca Raton, Boca Raton, Florida +1 locations
Conditions: Symptomatic Neurogenic Orthostatic Hypotension, MSA - Multiple System Atrophy
Study to Evaluate the Efficacy and Safety of DA-1241 in Subjects With Presumed NASH
Recruiting
A multicenter, randomized, double-blind, placebo-controlled, parallel, Phase 2a clinical trial to evaluate the efficacy and safety of DA 1241 in subjects with presumed non-alcoholic steatohepatitis (NASH).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
06/14/2024
Locations: Excel Medical Trials, Boca Raton, Florida
Conditions: NON-ALCOHOLIC STEATOHEPATITIS
A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy
Recruiting
Hidradenitis suppurativa (HS) is an inflammatory skin disease that causes painful lesions in the axilla (underarm), inguinal (groin) and anogenital (anal/genital) regions. This study will assess how safe and effective upadacitinib is in treating adult and adolescent participants with moderate to severe HS who have failed to respond to or are intolerant of anti-tumor necrosis factor (TNF) therapy. Adverse events and change in disease activity will be assessed. Upadacitinib is an approved drug fo... Read More
Gender:
All
Ages:
12 years and above
Trial Updated:
06/14/2024
Locations: Skin Care Research Boca Raton /ID# 253814, Boca Raton, Florida
Conditions: Hidradenitis Suppurativa
Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Adolescent ORION-16 or ORION-13 Studies
Recruiting
The purpose of this open-label, single arm, multicenter extension study is to evaluate the long-term safety and tolerability of inclisiran in participants with HeFH or HoFH who have completed the ORION-16 or ORION-13 studies.
Gender:
All
Ages:
12 years and above
Trial Updated:
06/13/2024
Locations: Excel Medical Clinical Trials LLC, Boca Raton, Florida
Conditions: Heterozygous or Homozygous Familial Hypercholesterolemia