There are currently 167 clinical trials in Boca Raton, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Boca Raton Regional Hospital, Parkinson's Disease and Movement Disorders Center of Boca Raton, GSK Investigational Site and Excel Medical Clinical Trials. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease
NCT06031844
Recruiting
This Phase 2a clinical trial will evaluate the effectiveness, safety, and tolerability of increasing dose strengths of an oral daily medication, DFV890, administered for 12 weeks, to reduce key markers of inflammation related to CVD risk, such as IL-6 and IL-18, in approximately 24 people with known heart disease and an elevated marker of inflammation, hsCRP.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
06/03/2024
Locations: Excel Medical Clinical Trials LLC, Boca Raton, Florida
Conditions: Coronary Heart Disease
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A Clinical Study to Assess the Efficacy and Safety of Alpha DaRT224 for the Treatment of Patients With Recurrent Cutaneous Squamous Cell Carcinoma
NCT05323253
Recruiting
This is a multi-center clinical study enrolling up to 86 participants. The primary objectives are to determine the objective response rate (ORR) established by the confirmed best overall response (BOR) following intratumoral administration of DaRT - Diffusing Alpha-Emitters Radiation Therapy, as well as to assess the Duration of Response (DOR) 6 months from initial response. Secondary objectives are to assess the safety of DaRT, and to assess the progression free survival (PFS), overall survival... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: Boca Raton Regional Hospital, Boca Raton, Florida
Conditions: Recurrent Squamous Cell Carcinoma
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A Study Evaluating the Efficacy and Safety of Mosunetuzumab in Combination With Lenalidomide in Comparison to Rituximab in Combination With Lenalidomide With a US Extension of Mosunetuzumab in Combination With Lenalidomide in Participants With Follicular Lymphoma
NCT04712097
Recruiting
This study will evaluate the efficacy and safety of mosunetuzumab in combination with lenalidomide (M + Len) compared to rituximab in combination with lenalidomide (R + Len) in participants with relapsed or refractory (R/R) follicular lymphoma (FL) who have received at least one line of prior systemic therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: Lynn Cancer Institute/Boca Raton Regional Hospital, Boca Raton, Florida
Conditions: Relapsed or Refractory Follicular Lymphoma
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Evaluation of Branch Endografts in the Treatment of Aortic Aneurysms
NCT01524211
Recruiting
Zenith t-Branch Study Cohort: The purpose of this study is to collect information on the Cook Zenith t-Branch endovascular stent-graft system and the Terumo Arch Branch for the treatment of aortic aneurysms. Terumo Arch Branch Study Cohort: The purpose of this additional study arm to the current IDE clinical trial is to collect a priori information on the Terumo Arch Branch Endograft for the treatment of proximal thoracic aortic pathologies that cannot be treated with conventional thoracic endo... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: Baptist Health South Florida|Boca Raton Regional Hospital (BRRH), Boca Raton, Florida
Conditions: Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm
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Study in Atrial Fibrillation (AF) Patients at High Risk of Stroke
NCT05421533
Recruiting
The GARDENIA registry will collect real-world clinical data on the anticoagulant strategies in patients with AF at elevated risk of stroke but also elevated risk of bleeding.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/03/2024
Locations: Anthos Investigative Site, Boca Raton, Florida
Conditions: Atrial Fibrillation
Register for Updates
A Study to Test Radium-223 With Docetaxel in Patients With Prostate Cancer
NCT03574571
Recruiting
The purpose of this study is to compare any good and bad effects of using radium-223 along with docetaxel chemotherapy treatment versus using docetaxel alone. Earlier studies helped show that the combination is safe, but the combination has not been proven to work better than either drug alone. The goal of this study is to find out if combining docetaxel and radium-223 is better than giving either drug by itself.
Gender:
Male
Ages:
18 years and above
Trial Updated:
05/31/2024
Locations: Boca Raton Regional Hospital, Boca Raton, Florida
Conditions: Prostate Cancer
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AMX0035 and Progressive Supranuclear Palsy
NCT06122662
Recruiting
ORION Trial is a trial to evaluate the efficacy and safety of AMX0035 in participants with Progressive Supranuclear Palsy (PSP), consisting of a randomized double blind placebo controlled phase, followed by an optional open-label extension phase.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
05/31/2024
Locations: Parkinson's Disease and Movement Disorders Center of Boca Raton, Boca Raton, Florida
Conditions: Progressive Supranuclear Palsy, PSP, Neurodegenerative Diseases, Atypical Parkinsonism
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A Study to Compare the Safety and Efficacy of Dysport® and Botox® in Adults With Upper Limb Spasticity.
NCT04936542
Recruiting
This study is aiming to demonstrate the non-inferiority of AbobotulinumtoxinA (aboBoNT-A) versus OnabotulinumtoxinA (onaBoNT-A) as the primary safety endpoint, and the superiority of aboBoNT-A over onaBoNT-A with respect to duration of response as the key secondary efficacy endpoint when used at optimal doses according to approved prescribing information of each product.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/30/2024
Locations: First Choice Neurology, Boca Raton, Florida
Conditions: Upper Limb Spasticity
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Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD
NCT05819359
Recruiting
The purpose of this randomized, double-blind, placebo-controlled study is to assess the efficacy of BIA 28-6156 over placebo in delaying clinical meaningful motor progression over 78 weeks in subjects with Parkinson's disease who have a pathogenic variant in the glucocerebrosidase 1 (GBA1) gene (GBA-PD).
Gender:
All
Ages:
Between 35 years and 80 years
Trial Updated:
05/29/2024
Locations: Parkinson's Center and Movement Disorders of Boca Raton, Boca Raton, Florida
Conditions: Parkinson's Disease
Register for Updates
A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy
NCT05923866
Recruiting
This is a Phase 2, double-blind, parallel-group, placebo-controlled study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of multiple doses of ONO-2808 in patients with MSA. This is the first study of ONO-2808 in patients with MSA.
Gender:
All
Ages:
Between 30 years and 80 years
Trial Updated:
05/29/2024
Locations: Parkinson's Disease and Movement Disorders Center, Boca Raton, Florida
Conditions: Multiple System Atrophy (MSA)
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Parkinson's Foundation PD GENEration Genetic Registry
NCT04994015
Recruiting
Development of a central repository for PD-related genomic data for future research.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/28/2024
Locations: Parkinson's Disease & Movement Disorder Center of Boca Raton, Boca Raton, Florida
Conditions: Parkinson's Disease
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Study to Continue Treatment With Darolutamide in Patients Who Have Been Participating in Previous Darolutamide Studies Supported by Bayer
NCT04464226
Recruiting
The aim of this study is to provide darolutamide treatment to patients who participated in a previous study with darolutamide supported by Bayer and the treating doctor considers that the continuation of the treatment with darolutamide to be beneficial. Patients will be carried over from the previous studies and continue in this study with darolutamide treatment on the same dosage. They will also return to the study centers for doctor's visits as often as they did in the previous study.
Gender:
Male
Ages:
18 years and above
Trial Updated:
05/27/2024
Locations: Boca Raton Regional Hospital, Boca Raton, Florida
Conditions: Cancer
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