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Diabetes Paid Clinical Trials in Indiana
A listing of 26 Diabetes clinical trials in Indiana actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
13 - 24 of 26
The state of Indiana currently has 26 active clinical trials seeking participants for Diabetes research studies. These trials are conducted in various cities, including Indianapolis, South Bend, Fort Wayne and Evansville.
Featured Trial
Studying an Investigational Treatment in Children with Type 2 Diabetes
Recruiting
The main objectives of this study are to confirm the effectiveness and safety of an investigational treatment in adolescents and children with type 2 diabetes. The study will also assess whether the investigational treatment can improve glucose control and reduce body weight. Participants will be randomly assigned to receive either the investigational treatment or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Pediatric
Type 2 Diabetes (T2DM)
Adolescent Trials
All Conditions
Featured Trial
Heart Failure Clinical Trial
Recruiting
You or someone you love may be eligible for a heart failure clinical study. Eligible participants will receive study-related assessments, care, and treatment at no cost. You may be reimbursed for travel while participating. See if you are eligible.
Conditions:
Heart Failure
Congestive Heart Failure
Chronic Heart Failure
Heart Failure
Congestive
Featured Trial
Studying an Investigational Medication to Manage Pain
Recruiting
This Phase 3 study aims to evaluate the safety and effectiveness of an investigational medication for adults experiencing pain associated with diabetes, specifically in the lower legs. The focus will be on the investigational medication's ability to reduce daily pain levels. Throughout the 14-week study, participants will be randomly assigned to receive either the investigational medication, an already-in-market drug, or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about compensation, study requirements, and risks/benefits. Expressing interest does not commit you to participating in the study; it simply allows you to learn more about it from the research site before making an informed decision.
Conditions:
All Conditions
Diabetic peripheral neuropathy (DPN)
Diabetes
Featured Trial
Assessing an Investigational Medication on Major Adverse Cardiovascular Events Such as Heart Attack and Stroke
Recruiting
The main purpose of this study is to evaluate the cardiovascular safety of the investigational medication compared with a placebo in participants who are at an increased risk of adverse cardiovascular outcomes (ie. heart attack and stroke). Participants will be randomly assigned to receive either the investigational medication or a placebo, with safety and tolerability being monitored throughout. Should you express interest, you will be contacted directly by the research site, who will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Ischemic heart disease (IHD)
Overweight
Metabolic syndrome
Diabetes related diseases
Cardiovascular Disease
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Studying an Investigational Vaccine for a Common Herpesvirus in Adolescents
Recruiting
This study aims to evaluate the safety, effectiveness, and immune response of an investigational vaccine targeting cytomegalovirus (CMV), a common type of herpesvirus. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. The study will monitor participants’ health and immune response over an 18-month period. Should you express interest for the adolescent in your care, you will be contacted directly by the research site. They will provide further details and address any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Preventative Trials
Healthy
All Conditions
Parent / Carer of child aged 0-17
Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)
Recruiting
A multi-center, placebo-controlled, double blind, 1:1:1 randomized control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes within 100 days of diagnosis.
Gender:
ALL
Ages:
Between 12 years and 35 years
Trial Updated:
10/17/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: Diabetes Mellitus, Type 1
Empowering Veterans to Actively Communicate and Engage in Shared Decision Making in Medical Visits, A Randomized Controlled Trial
Recruiting
Type 2 diabetes is a significant condition in VA affecting 20% of VA patients. Adherence to medication regimens and lifestyle factors is important to achieve care goals for these patients. Patients who use active participatory communication behaviors with their providers have better adherence to treatment and better biomedical outcomes, yet many patients are not prepared to engage in active communication with their providers. Existing coaching interventions have not been adopted in practice beca... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Adam Benjamin Jr VA Outpatient Clinic, Crown Point, IN, Crown Point, Indiana
Conditions: Diabetes Mellitus (Type 2)
Rituximab-pvvr and Abatacept Vs Rituximab-pvvr Alone in New Onset Type 1 Diabetes
Recruiting
The study is a two-arm, multicenter, double-blinded clinical trial testing sequential therapy with rituximab-pvvr followed by abatacept versus rituximab-pvvr alone in new onset T1D. The primary objective is to test whether the C-peptide response to a 2-hour mixed meal tolerance test, will be improved in participants with new onset T1D who are treated with Abatacept after Rituximab-pvvr compared to those treated with Rituximab-pvvr and placebo 24 months after enrollment.
Gender:
ALL
Ages:
Between 8 years and 45 years
Trial Updated:
09/27/2024
Locations: Indiana University - Riley Hospital for Children, Indianapolis, Indiana
Conditions: Type 1 Diabetes Mellitus
Heat Therapy in Type 2 Diabetes
Recruiting
This study aims to test whether home-based heat therapy (HT) can improve the health of older adults with type 2 diabetes (T2D). T2D is common in older adults and can lead to severe issues such as heart disease, disability, and early death. While regular exercise is known to help manage T2D, many people with the condition find it difficult to stay active. This study explores HT as a simple, non-invasive treatment that may offer similar benefits.
Participants will wear special leg sleeves that de... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
09/11/2024
Locations: Purdue University, West Lafayette, Indiana
Conditions: Type 2 Diabetes
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
Recruiting
Obesity prevalence in persons with T1D has increased, which further complicates management and risk for complications. The proposed study is relevant to public health because it helps us understand the role of the gut microbiome in disease pathophysiology in T1D youth with obesity as well as potential mechanisms to modify disease.
Gender:
ALL
Ages:
Between 11 years and 18 years
Trial Updated:
09/10/2024
Locations: Indiana University School of Medicine, Indianapolis, Indiana
Conditions: Type 1 Diabetes, Obesity
Mechanisms Underlying Impaired Diabetic Wound Healing
Recruiting
The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
09/04/2024
Locations: Comprehensive Wound Care Centers, Indianapolis, Indiana
Conditions: Non-healing Wounds, Diabetes
Type 1 Diabetes Extension Study
Recruiting
This is a multi-center, prospective, non-interventional study that focuses on the long- term effects following participation in selected ITN new-onset Type1 Diabetes Mellitus studies with immunomodulatory agents (T1DM, T1D).
This observational study will:
* follow participants to determine how long they continue to produce insulin, and
* will also assess how changes in the immune system over time relate to the ability to produce insulin.
This information could help design better therapies for... Read More
Gender:
ALL
Ages:
Between 8 years and 35 years
Trial Updated:
08/27/2024
Locations: Indiana University Riley Hospital for Children, Indianapolis, Indiana
Conditions: Type 1 Diabetes Mellitus, T1DM, T1D
A Study to Inv. Safety, Efficacy & PD of Dasiglucagon as Hypoglycemia Rescue Therapy in Children <6 Years With T1D
Recruiting
This research study will investigate whether dasiglucagon as a rescue therapy for participants under 6 years of age works and is safe to use. In addition, the study will investigate how dasiglucagon works in the body (pharmacokinetics and pharmacodynamics).
Participants will receive 1 single dose as an injection under the skin (subcutaneous, s.c.) into the buttocks.
Participants will have 3 visits with the study team. For each participant, the study will last up to 84 days.
Gender:
ALL
Ages:
5 years and below
Trial Updated:
08/27/2024
Locations: Indiana University School of Medicine, Indianapolis, Indiana
Conditions: Hypoglycemia, Type 1 Diabetes
TArgeting Type 1 Diabetes Using POLyamines (TADPOL)
Recruiting
The goal of this clinical trial is to test a drug known as DFMO in people with Type 1 Diabetes (T1D). The main question\[s\] it aims to answer are:
* Does it reduce stress on the cells that make insulin?
* Does it preserve what is left of the body's insulin production? Participants will take either DFMO or a placebo (looks like DFMO but has no active ingredients) two times a day for about 6 months. Participants will have 6 in person visits and 1 phone visit over a period of 12 months. Visits wi... Read More
Gender:
ALL
Ages:
Between 4 years and 40 years
Trial Updated:
08/08/2024
Locations: IU Health Riley Hospital for Children, Indianapolis, Indiana
Conditions: Type 1 Diabetes
Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
Recruiting
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
06/09/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: Gestational Diabetes, Pregnancy, High Risk, Overweight and Obesity
Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes
Recruiting
Aim 1: Characterize shared decision-making and unmet patient-caregiver dyads needs for patients with diabetes and Alzheimer's Disease and related dementias (ADRD) while using a continuous glucose monitoring (CGM) device.
Aim 2: Develop an interactive tool to enhance shared decision-making for diabetes management.
Gender:
All
Ages:
65 years and above
Trial Updated:
04/17/2024
Locations: Eskenazi Health, Indianapolis, Indiana
Electronic Diabetes Tune-Up Group (eDTU) for African Americans
Recruiting
The primary aims of this study are:
To test the acceptability and feasibility of the electronic DTU intervention (eDTU) that has been adapted for cultural relevance and online delivery compared to waitlist control and the in-person DTU (iDTU). The hypothesis is that the adapted intervention will be culturally acceptable (by participant satisfaction scores) and well-subscribed (intervention attendance rates).
To test differences in diabetes distress and A1c change scores between intervention (ch... Read More
Gender:
Female
Ages:
21 years and above
Trial Updated:
03/13/2024
Locations: Indiana University School of Medicine, Indianapolis, Indiana
Conditions: Diabetes Mellitus, Type 2, Diabetes Complications
13 - 24 of 26