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Diabetes Paid Clinical Trials in Indiana
A listing of 27 Diabetes clinical trials in Indiana actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
13 - 24 of 27
The state of Indiana currently has 27 active clinical trials seeking participants for Diabetes research studies. These trials are conducted in various cities, including Indianapolis, South Bend, Fort Wayne and Evansville.
Featured Trial
Studying an Investigational Monitoring System in Adults with Type 2 Diabetes
Recruiting
The main objectives of this study are to assess the safety and effectiveness of an investigational continuous glucose monitoring system compared to routine care in adults with type 2 diabetes. Additionally, the study aims to evaluate the quality of life improvements that may come with using the investigational device. Should you express interest, you will be contacted directly by the research site, who will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
All Conditions
Type 2 Diabetes (T2DM)
Featured Trial
Studying an Investigational Medication's Impact on Cardiovascular Events
Recruiting
The main objectives of this Phase 3 study are to evaluate the safety and effectiveness of an investigational medication's ability to reduce major adverse cardiovascular events (such as heart attacks and strokes) in adults at risk. Participants will be randomly assigned to receive either the investigational medication or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
All Conditions
Hyperlipidemia
Cardiovascular Disease
Ischemic heart disease (IHD)
Stroke
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Study
Recruiting
Are you tired of living with chronic cough? The ASPIRE Study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough. You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you.
Conditions:
Chronic Cough
Refractory or Unexplained Chronic Cough
Cough
Asthma
Allergic Asthma
Featured Trial
Studying an Investigational Virus Vaccine
Recruiting
The main objectives of this study are to assess the safety and effectiveness of an investigational vaccine aimed at preventing norovirus, commonly known as the stomach flu. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Healthy
Interested in vaccine studies
All Conditions
Preventative Trials
Featured Trial
Diabetic Peripheral Neuropathy Clinical Study (Raleigh)
Recruiting
If you struggle with chronic nerve pain in your legs due to diabetes (diabetic peripheral neuropathy, or DPN), Vertex Pharmaceuticals is conducting research studies that may be an option.
Conditions:
Diabetic Peripheral Neuropathy
Diabetes
Type 2 Diabetes
TArgeting Type 1 Diabetes Using POLyamines (TADPOL)
Recruiting
The goal of this clinical trial is to test a drug known as DFMO in people with Type 1 Diabetes (T1D). The main question\[s\] it aims to answer are:
* Does it reduce stress on the cells that make insulin?
* Does it preserve what is left of the body's insulin production? Participants will take either DFMO or a placebo (looks like DFMO but has no active ingredients) two times a day for about 6 months. Participants will have 6 in person visits and 1 phone visit over a period of 12 months. Visits wi... Read More
Gender:
ALL
Ages:
Between 4 years and 40 years
Trial Updated:
02/14/2025
Locations: IU Health Riley Hospital for Children, Indianapolis, Indiana
Conditions: Type 1 Diabetes
Phase 2b Trial Comparing HDV-Insulin Lispro to Insulin Lispro in Adults With Type 1 Diabetes Receiving Insulin Degludec
Recruiting
The goal of this study is to see if directing insulin to the liver will improve the low blood sugar that sometimes happens when injecting insulin in Type 1 diabetes patients. Participants will use continuous glucose monitoring to measure the sugar levels in their blood, and work with the doctor to find the best doses. One group of patients will get the liver targeting insulin, and the other group will use insulin they normally use for treating Type 1 diabetes. The participant will be part of the... Read More
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
12/05/2024
Locations: Indiana Medical Research Institute, Merrillville, Indiana
Conditions: Diabetes Mellitus, Type 1
Denosumab for Type 1 Diabetes
Recruiting
Type 1 diabetes (T1D) arises from abnormal immune cell-mediated injury to beta cells that make insulin. The injured beta cells can then no longer make the needed amount of insulin to stay healthy. However, in the early stages of T1D, some beta cells are still alive and functioning. Treatment to protect the beta cells against injury at this time could slow the progress of disease. Denosumab is an approved treatment for osteoporosis (a disease that thins and weakens the bones), high blood calcium... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
12/03/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: Type 1 Diabetes
Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)
Recruiting
A multi-center, placebo-controlled, double blind, 1:1:1 randomized control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes within 100 days of diagnosis.
Gender:
ALL
Ages:
Between 12 years and 35 years
Trial Updated:
10/17/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: Diabetes Mellitus, Type 1
Empowering Veterans to Actively Communicate and Engage in Shared Decision Making in Medical Visits, A Randomized Controlled Trial
Recruiting
Type 2 diabetes is a significant condition in VA affecting 20% of VA patients. Adherence to medication regimens and lifestyle factors is important to achieve care goals for these patients. Patients who use active participatory communication behaviors with their providers have better adherence to treatment and better biomedical outcomes, yet many patients are not prepared to engage in active communication with their providers. Existing coaching interventions have not been adopted in practice beca... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Adam Benjamin Jr VA Outpatient Clinic, Crown Point, IN, Crown Point, Indiana
Conditions: Diabetes Mellitus (Type 2)
Rituximab-pvvr and Abatacept Vs Rituximab-pvvr Alone in New Onset Type 1 Diabetes
Recruiting
The study is a two-arm, multicenter, double-blinded clinical trial testing sequential therapy with rituximab-pvvr followed by abatacept versus rituximab-pvvr alone in new onset T1D. The primary objective is to test whether the C-peptide response to a 2-hour mixed meal tolerance test, will be improved in participants with new onset T1D who are treated with Abatacept after Rituximab-pvvr compared to those treated with Rituximab-pvvr and placebo 24 months after enrollment.
Gender:
ALL
Ages:
Between 8 years and 45 years
Trial Updated:
09/27/2024
Locations: Indiana University - Riley Hospital for Children, Indianapolis, Indiana
Conditions: Type 1 Diabetes Mellitus
Heat Therapy in Type 2 Diabetes
Recruiting
This study aims to test whether home-based heat therapy (HT) can improve the health of older adults with type 2 diabetes (T2D). T2D is common in older adults and can lead to severe issues such as heart disease, disability, and early death. While regular exercise is known to help manage T2D, many people with the condition find it difficult to stay active. This study explores HT as a simple, non-invasive treatment that may offer similar benefits.
Participants will wear special leg sleeves that de... Read More
Gender:
ALL
Ages:
55 years and above
Trial Updated:
09/11/2024
Locations: Purdue University, West Lafayette, Indiana
Conditions: Type 2 Diabetes
Mechanisms Underlying Impaired Diabetic Wound Healing
Recruiting
The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
09/04/2024
Locations: Comprehensive Wound Care Centers, Indianapolis, Indiana
Conditions: Non-healing Wounds, Diabetes
A Study to Inv. Safety, Efficacy & PD of Dasiglucagon as Hypoglycemia Rescue Therapy in Children <6 Years With T1D
Recruiting
This research study will investigate whether dasiglucagon as a rescue therapy for participants under 6 years of age works and is safe to use. In addition, the study will investigate how dasiglucagon works in the body (pharmacokinetics and pharmacodynamics).
Participants will receive 1 single dose as an injection under the skin (subcutaneous, s.c.) into the buttocks.
Participants will have 3 visits with the study team. For each participant, the study will last up to 84 days.
Gender:
ALL
Ages:
5 years and below
Trial Updated:
08/27/2024
Locations: Indiana University School of Medicine, Indianapolis, Indiana
Conditions: Hypoglycemia, Type 1 Diabetes
Type 1 Diabetes Extension Study
Recruiting
This is a multi-center, prospective, non-interventional study that focuses on the long- term effects following participation in selected ITN new-onset Type1 Diabetes Mellitus studies with immunomodulatory agents (T1DM, T1D).
This observational study will:
* follow participants to determine how long they continue to produce insulin, and
* will also assess how changes in the immune system over time relate to the ability to produce insulin.
This information could help design better therapies for... Read More
Gender:
ALL
Ages:
Between 8 years and 35 years
Trial Updated:
08/27/2024
Locations: Indiana University Riley Hospital for Children, Indianapolis, Indiana
Conditions: Type 1 Diabetes Mellitus, T1DM, T1D
Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
Recruiting
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
06/09/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: Gestational Diabetes, Pregnancy, High Risk, Overweight and Obesity
Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes
Recruiting
Aim 1: Characterize shared decision-making and unmet patient-caregiver dyads needs for patients with diabetes and Alzheimer's Disease and related dementias (ADRD) while using a continuous glucose monitoring (CGM) device.
Aim 2: Develop an interactive tool to enhance shared decision-making for diabetes management.
Gender:
All
Ages:
65 years and above
Trial Updated:
04/17/2024
Locations: Eskenazi Health, Indianapolis, Indiana
13 - 24 of 27