There are currently 465 clinical trials in Kansas City, Kansas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Kansas Medical Center, University of Kansas Cancer Center, Kansas University Medical Center and Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Evaluating the Tolerability and Effects of Berberine on Major Metabolic Biomarkers: A Pilot Study
NCT03976336
Recruiting
Berberine is a dietary supplement that comes from the roots, stems, and bark of various plants and has been used for centuries in traditional Chinese medicine. It may help lower cholesterol, lower blood sugar, and reduce inflammation.Very few studies have been done in the United States to show how berberine effects cholesterol and blood sugar. This study is looking to see how berberine changes cholesterol and blood sugar, and to see how well it is tolerated.Berberine is not a prescription medica... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Metabolic Syndrome
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A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF)
NCT05668741
Recruiting
The purpose of this study is to evaluate the safety, and tolerability and efficacy of VX-522 in participants 18 years of age and older with cystic fibrosis and a cystic fibrosis transmembrane conductance regulator (CFTR) genotype not responsive to CFTR modulator therapy.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/08/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Cystic Fibrosis
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Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer
NCT05382286
Recruiting
The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) and pembrolizumab versus treatment of physician's choice (TPC) and pembrolizumab in participants with previously untreated, locally advanced inoperable or metastatic triple-negative breast cancer, whose tumors express programmed cell death ligand 1 (PD-L1).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/08/2024
Locations: The University of Kansas Cancer Center,2000 Olathe Blvd, Kansas City, Kansas
Conditions: Triple Negative Breast Cancer, PD-L1 Positive
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MRI for Screening and Monitoring Scleroderma ILD
NCT05204355
Recruiting
The purpose of this study is to test MRI methods for evaluating patients with Scleroderma-associated interstitial lung disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Scleroderma
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Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome
NCT05419011
Recruiting
This phase IIb trial tests whether Tri-Ad5 in combination with N-803 works to prevent colon and other cancers in participants with Lynch syndrome. Each of the three injections in Tri-Ad5 vaccine contain a different substance that is in precancer and cancer cells. Injecting these substances may cause the immune system to develop a defense against cancer that recognizes and destroys any precancer and cancer cells that produce these proteins in the future. N-803 may increase immune responses to oth... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: University of Kansas Cancer Center, Kansas City, Kansas
Conditions: Lynch Syndrome
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Developing Hyperpolarized 129Xe MRI Biomarkers for Evaluation of Pulmonary Arterial Hypertension
NCT05339386
Recruiting
In this study, hyperpolarized 129Xe MRI will be used to evaluate treatment efficacy in patients with pulmonary arterial hypertension (PAH). Participants will be imaged at 4 timepoints (baseline, 6 weeks post-therapy initiation, 12 weeks, and 18 weeks). Images will be analyzed to develop new biomarkers and to understand treatment effects.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Pulmonary Arterial Hypertension
Register for Updates
A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placebo for the Treatment of Participants With Mycobacterium Avium Complex (MAC) Pulmonary Disease
NCT05496374
Recruiting
The purpose of the study is to evaluate The microbiological response and clinical efficacy of SPR720 compared with placebo in participants with nontuberculous mycobacteria pulmonary disease (NTM-PD). The safety and tolerability of SPR720 in a participants population with NTM- PD The pharmacokinetic (PK) of SPR719, active moiety, following orally (po) administered prodrug SPR720 in a participant population with NTM-PD.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/07/2024
Locations: Medical Facility, Kansas City, Kansas
Conditions: Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD)
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Autologous Muscle Derived Cells Compared to Placebo for Urinary Sphincter Repair in Post-surgical Female Stress Incontinence
NCT03104517
Recruiting
This study evaluates the efficacy and safety of Autologous Muscle Derived Cells for Urinary Sphincter Repair (AMDC-USR; generic name: iltamiocel) compared to a placebo in the reduction of stress incontinence episode frequency in adult female patients with post-surgical persistent or recurrent stress urinary incontinence (SUI). Half of the participants will receive AMDC-USR (injections with cells) and the other half will receive placebo.
Gender:
Female
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Kansas Health System, Kansas City, Kansas
Conditions: Stress Urinary Incontinence
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Quantitative Pulmonary Imaging Registry & Biorepository
NCT05530408
Recruiting
The goal of this project is to establish a registry and biorepository of images and biological samples from subjects undergoing novel pulmonary imaging methods to be used for future research aimed toward identifying clinical applications of imaging methods and toward understanding the physiological significance of imaging biomarkers. This registry and biorepository will accelerate the development of these imaging techniques and may lead toward future clinical adoption of quantitative pulmonary i... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Pulmonary Disease
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The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)
NCT05762302
Recruiting
This is a Prospective, multi-center study enrolling adults subjects presented to the ED/Urgent care, with symptoms consistent with lower respiratory infection (LRTI). The reason of this study is to demonstrate the MeMed BV can help clinicians make decisions about using antibiotics in patients with lower respiratory track infections and see how it would impact clinical outcomes, antibiotics use, hospitalizations, ED clinicians find ways to improve health and medical care.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
05/06/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Lower Respiratory Tract Infection
Register for Updates
An Open-label Study of Ozanimod in Moderate to Severe Ulcerative Colitis in Clinical Practice
NCT05369832
Recruiting
The purpose of this study is to explore the safety, efficacy, effects on quality of life (QOL), and biomarker response of ozanimod in participants with moderate to severely active ulcerative colitis (UC) in clinical practice.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Colitis, Ulcerative
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Hyperpolarized 129Xe MRI Lung Health Cohort
NCT05766384
Recruiting
A subset of young adults participating in the American Lung Association (ALA) Lung Health Cohort (LHC) will be imaged using Hyperpolarized 129Xe MRI to assess lung structure and function. Images will be used to improve the understanding of lung health and early lung abnormalities that may lead to chronic lung disease.
Gender:
All
Ages:
Between 25 years and 35 years
Trial Updated:
05/06/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Healthy
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