There are currently 446 clinical trials in Kansas City, Kansas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Kansas Medical Center, University of Kansas Cancer Center, Kansas University Medical Center and Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Regenn® Therapy System Safety Study
NCT06259409
Recruiting
The goal of this clinical trial is to evaluate the safety of the investigational device, Regenn® Negative Pressure Therapy System (Regenn® Therapy), a form of Negative Pressure Wound Therapy (NPWT), in the post-operative surgical wounds of patients undergoing lumbar spinal fusion surgeries. The main questions the study aims to answer are: * The device-related serious adverse event rate. * Patient post-operative pain as assessed using a validated pain measurement scoring system. * The number and... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/04/2024
Locations: The University of Kansas Medical Center, Kansas City, Kansas
Conditions: Surgical Wound
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Open-label Study to Evaluate the Safety of Various Dosing Regimens of MuSK-CAART for MuSK Myasthenia Gravis
NCT05451212
Recruiting
Muscle-specific tyrosine kinase (MuSK) myasthenia gravis (MG) is a rare but potentially severe disease, in which patients develop pathogenic autoantibodies that specifically target the MuSK protein in the neuromuscular junction. This phase 1 study is being conducted to evaluate the safety of various dosing regimens of an investigational cell therapy, MuSK-CAART, that can be given to patients with anti-MuSK antibody positive Myasthenia Gravis (MuSK MG), who have active disease. Various dosing reg... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/25/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: MuSK Myasthenia Gravis
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Opioid-Free Pain Treatment in Trauma Patients
NCT06078371
Recruiting
Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/22/2024
Locations: The University of Kansas Medical Center, Kansas City, Kansas
Conditions: Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture, Patella Fracture, Tibial Shaft Fracture With or Without Associated Fibula Fracture, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Tibial Pilon Fracture, Talar Head, Neck, Body, or Process Fractures, Calcaneus Fractures, Lisfranc Injuries, Isolated or Multiple Metatarsal Fractures, Phalanx Fractures of the Foot, Single or Multiple, Clavicle Fractures, Proximal Humerus Fractures, Humeral Shaft Fractures, Distal Humerus Fractures (Intra or Extra-articular), Olecranon Fractures, Radial Head or Neck Fractures, Elbow Fractures Involving a Combination of Fractures of the Radius and Uln, Forearm Fractures (Both Bone Forearm Fractures, Isolated Ulnar Shaft, Isolated Radial Shaft), Distal Radius Fractures
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Lenrispodun as Adjunctive Therapy in the Treatment of Patients With Motor Fluctuations Due to Parkinson's Disease
NCT05766813
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, fixed-dose study in patients with a diagnosis of Parkinson's Disease consistent with the UK Parkinson's Disease Society (UKPDS) Brain Bank diagnostic criteria, who are experiencing wearing off symptoms and levodopa-induced dyskinesia.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
10/21/2024
Locations: Clinical Site, Kansas City, Kansas
Conditions: Parkinson Disease
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Evaluation of Multi-Tined Expandable Electrode (MEE) Efficacy and Safety in Treatment of Lumbar Facet Arthropathy by Radiofrequency Neurotomies Compared to Conservative Medical Management.
NCT04730700
Recruiting
The purpose of this study is to better understand how people feel after a radiofrequency ablation standard of care surgery using a different type of needle (multi-tined expandable electrode/MEE) in comparison to receiving conventional medical management (CMM) techniques.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/18/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Chronic Low-back Pain
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Early Versus Delayed Urinary Catheter Removal After Minimally Invasive Lumbar Spine Surgery
NCT05359926
Recruiting
The study aims to compare between early versus delayed urinary catheter removal the impact on time to ambulation (in minutes) after minimally invasive lumbar spine surgery
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Foley Catheterization, Ambulation
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Comparing Telehealth-Delivered CBT-I to Web-Based CBT-I to Enhance Sleep, Reduce Fatigue, and Promote Neuroprotection
NCT06434571
Recruiting
The objective of this RCT is to assess the efficacy of one-on-one telehealth CBT-I (tCBT-I) compared to web-based CBT-I (wCBT-I) and treatment as usual (TAU) to improve sleep outcomes (Aim 1), fatigue and quality of life (Aim 2), and promote neuroprotection (Exploratory Aim 3), and to explore the characteristics of participants that predict improvement in sleep outcomes (Exploratory Aim 4). Reassessment of outcomes will be completed after the 6-week intervention and 6 months following completion... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/15/2024
Locations: University of Kansas Medical Center- Sleep, Health and Wellness Laboratory, Kansas City, Kansas
Conditions: Multiple Sclerosis, Insomnia
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Exosomes in Rectal Cancer
NCT03874559
Recruiting
The primary aims of this study is to characterize exosomal biomarker levels in patients with locally advanced rectal cancer undergoing neoadjuvant chemoradiation therapy. Compare rates of exosomal expression before during and after chemoradiation therapy with pathologic response rates at the time of APR or LAR. The researchers will also examine the functionality of these exosomes in malignant colonic organoids and mouse models of colorectal cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/11/2024
Locations: University of Kansas Medical Center/ Cancer Center, Kansas City, Kansas
Conditions: Rectal Cancer
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LaserEn: SOLTIVE™ Thulium Laser Fiber En Bloc Resection of Bladder Tumors
NCT04979156
Recruiting
Conventional monopolar or bipolar transurethral resection of bladder tumors is the most common method for resection of a bladder mass. En bloc resection has demonstrated success in the literature utilizing different techniques and lasers, including utilizing the Ho:YAG and Tm:YAG lasers. A recent metanalysis revealed several benefits to laser en bloc resection including less complications and lower recurrence rate.22 Subsequently, laser technology has also advanced with the development of a supe... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/11/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Bladder Cancer, Surgery
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HoLEP Prior to Radiation Therapy for Patients With LUTS/Retention and Concurrent Prostate Cancer
NCT03802851
Recruiting
To determine if holmium laser enucleation of the prostate (HoLEP) for the treatment of lower urinary tract symptoms (LUTS) and/or urinary retention alters the treatment course for patients concurrently diagnosed with prostate cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: University of Kansas Health System, Kansas City, Kansas
Conditions: Prostate Cancer, Lower Urinary Tract Symptoms
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Interstitial Lung Disease Research Unit Biobank
NCT05392881
Recruiting
Establish a interstitial lung disease (ILD) registry and biorepository to lead towards a further understanding of the disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/07/2024
Locations: The University of Kansas Medical Center, Kansas City, Kansas
Conditions: Interstitial Lung Disease, Sarcoidosis, Idiopathic Pulmonary Fibrosis, Pulmonary Fibrosis, Hypersensitivity Pneumonitis
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Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft
NCT06379724
Recruiting
Investigators hypothesize that topical tranexamic acid will have better or comparable efficacy to topical thrombin in reducing hematoma formation at the wound base. The purpose of the study is to demonstrate that topical tranexamic acid will be a non-inferior alternative medication to the current standard of care,THROMBIN-JMI® , and at a lower cost to the health system.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/03/2024
Locations: The University of Kansas Health System, Kansas City, Kansas
Conditions: Burns, Skin Graft Complications
Register for Updates