The state of Kentucky currently has 17 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Louisville, Lexington, Owensboro and Paducah.
The Use of Low Dose Metronidazole to Decrease Postoperative Pain After Endometriosis Surgery
Recruiting
The purpose of this study is to determine a difference in participant reported pain after endometriosis surgery in participants given oral metronidazole versus placebo.
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
10/25/2023
Locations: University of Louisville Hospital, Louisville, Kentucky
Conditions: Endometriosis, Endometriosis-related Pain
A Dose-Finding Study to Evaluate the Efficacy and Safety of GSK3858279 in Adults With Knee Osteoarthritis Pain
Recruiting
This is dose-finding study of GSK3858279 in participants with moderate to severe knee osteoarthritis (OA) pain. The purpose of this study is to investigate and provide the data necessary to select the optimal effective and safe dose(s) of GSK3858279.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
10/11/2023
Locations: GSK Investigational Site, Louisville, Kentucky
Conditions: Pain
Telehealth Delivered Physical Rehabilitation for an Ankle Sprain
Recruiting
A vast majority (75-85%) of ankle sprain patients treated in emergency departments (ED) receive pain medication and are not referred for physical rehabilitation. Therefore, purpose of this study is to increase access to the standard of care for an ankle sprain by provide patients with physical rehabilitation delivered through telehealth. The purpose of this study includes compare a 2-week telehealth intervention to the usual care for treating 1) subjective function; 2) physical impairments; 3) m... Read More
Gender:
All
Ages:
Between 15 years and 35 years
Trial Updated:
07/05/2023
Locations: University of Kentucky, Lexington, Kentucky
Conditions: Ankle Sprains, Telerehabilitation, Analgesic, Opioid, Analgesics, Non-narcotic, Anti-Inflammatory Agents, Non-Steroidal, Implementation Science, Acute Pain, Quality of Life
Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI
Recruiting
The objective of this study is to identify the opioid-sparing effects, and pain-reduction potential of low dose, sub-dissociative ketamine on patients undergoing thoracic endovascular aortic repair (TEVAR) procedures receiving naloxone continuous infusion (NCI).
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
05/25/2023
Locations: University of Kentucky Medical Center, Lexington, Kentucky
Conditions: Descending Aortic Dissection, Postoperative Pain, Thoracoabdominal Aortic Aneurysm
Comparative Effectiveness of Online 8-session CBT vs. 1-Session Empowered Relief for Chronic Pain - The PROGRESS Study
Recruiting
The purpose of this study is to conduct a pragmatic clinical trial comparing the effectiveness of: (1) 8-week cognitive behavioral therapy for chronic pain (pain-CBT; sixteen hours total treatment time); and (2) a 1-session pain relief skills intervention for chronic pain (Empowered Relief; two hours total treatment time).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/21/2023
Locations: Humana, Louisville, Kentucky
Conditions: Pain, Chronic