There are currently 239 clinical trials in Baton Rouge, Louisiana looking for participants to engage in research studies. Trials are conducted at various facilities, including Pennington Biomedical Research Center, Mary Bird Perkins Cancer Center, LSU Health Baton Rouge-North Clinic and Louisiana Hematology Oncology Associates LLC. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
The Intestinal Microbiome in Triple Negative Breast Cancer Treated With Immunotherapy
NCT06318507
Recruiting
This study will determine how the intestinal microbiome differs between patients with obesity and early triple-negative breast cancer who achieve a pathologic complete response from preoperative anti-PD-1 immunotherapy (pembrolizumab) versus patients who do not.
Gender:
Female
Ages:
18 years and above
Trial Updated:
03/15/2024
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Breast Neoplasms
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Low Oxygen Exposure and Weight Status
NCT05289310
Recruiting
The objective of the proposed double-blind, parallel-arm, randomized clinical trial is to evaluate changes in body weight and composition, assess determinants of energy balance (intake and expenditure), and measure modulators of energy balance, following 8 wk of calorie restriction (-500 kcal/d) in combination with either overnight exposure to normobaric hypoxia (8 h/night, 15% FiO2, ~2640 m) or normoxia (8 h/night, 21% FiO2), using a commercially available, in-home tent system, in adults with o... Read More
Gender:
All
Ages:
Between 22 years and 65 years
Trial Updated:
03/14/2024
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Obesity
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A Weight Maintenance Program Promoting Fat Loss in Pregnancy in Women With Obesity
NCT04731688
Recruiting
The aims of this randomized controlled trial are to determine the effects of a lifestyle program that supports weight maintenance and fat mass loss during pregnancy in women with obesity on changes in 1) maternal weight, fat mass, and cardiometabolic risk factors; 2) safety measures, including fetal and neonatal growth; 3) the mediators and moderators of the fat mass loss intervention and 4) the effects gestational fat mass loss has on reducing incidence of adverse obstetrical outcomes, includin... Read More
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
03/13/2024
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Gestational Weight Gain, Obesity
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Understanding the Long-term Impact of COVID on Children and Families
NCT05172011
Recruiting
This is a combined retrospective and prospective, longitudinal, observational meta-cohort of individuals age 0-25 years who will enter the cohort with and without SARS-CoV-2 infection at varying stages before and after infection. Individuals with and without SARS-CoV-2 infection and with or without PASC symptoms will be followed to identify risk factors and occurrence of PASC. This study will be conducted in the United States and participants will be recruited through inpatient, outpatient, and... Read More
Gender:
All
Ages:
25 years and below
Trial Updated:
03/04/2024
Locations: Louisiana State University (LSU) - Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: SARS-CoV-2 Infection
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PATHFINDER 2: A Multi-Cancer Early Detection Study
NCT05155605
Recruiting
This is a prospective, multi-center interventional study of the GRAIL multi-cancer early detection (MCED) test with return of test results for participants enrolled through healthcare systems in North America. The purpose of this study is to evaluate the safety and performance of the GRAIL MCED test in a population of individuals who are eligible for guideline-recommended cancer screening. In cases with a "cancer signal detected" test result, participants will undergo diagnostic procedures based... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
03/01/2024
Locations: Ochsner Grove, Baton Rouge, Louisiana
Conditions: Early Detection of Cancer, Cancer
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Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)"
NCT03890861
Recruiting
The RAATE proposal is designed to determine the effects of physical activity on risk factors for Alzheimer's Disease in older African American adults. The study will compare a physical activity program to an active control group. There are three main objectives of the protocol: 1) to determine if a physical activity intervention tailored to older African American adults is effective in modifying cognitive function associated with Alzheimer's Disease, 2) to determine if a physical activity interv... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
02/26/2024
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Dementia, Alzheimer Type
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Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
NCT04815720
Recruiting
The purpose of the study is to evaluate the safety and tolerability of pepinemab in combination with pembrolizumab as first-line treatment and determine a recommended Phase 2 dose (RP2D) in patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC).
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
02/26/2024
Locations: Hematology/Oncology Clinic-Baton Rouge, Baton Rouge, Louisiana
Conditions: Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (HNSCC)
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Molecular Transducers of Physical Activity Consortium
NCT03960827
Recruiting
The goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity (PA). To achieve this aim, a mechanistic randomized controlled trial (RCT) is conducted, in which adult study participants are randomized to endurance exercise (EE) training, resistance exercise (RE) training, or no exercise Control for a period of approximately 12 weeks. The overarching hypothesis is that there are discoverable molecular tran... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2024
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Physical Activity
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Measurement of Energy Metabolism in Infants
NCT02683473
Recruiting
The purpose of this study is to measure energy expenditure during the first 3 months of life in infants.
Gender:
All
Ages:
Between 1 month and 3 months
Trial Updated:
02/21/2024
Locations: Pennington Biomedical Research Center, Baton Rouge, Louisiana
Conditions: Infant Development, Infant Overnutrition
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Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
NCT05855200
Recruiting
The primary purpose of this study is to evaluate the efficacy of perioperative dostarlimab compared with standard of care (SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon cancer.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/18/2024
Locations: GSK Investigational Site, Baton Rouge, Louisiana
Conditions: Colonic Neoplasms, Neoplasms, Colon
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Reducing African American's Alzheimer's Risk Through Exercise-Mild Cognitive Impairment (RAATE-MCI)
NCT04956549
Recruiting
The RAATE-MCI proposal is designed to determine the effects of physical activity on risk factors for Alzheimer's Disease in older African American adults. The study will compare a physical activity program to an active control group. RAATE-MCI is a 52-week randomized controlled trial. 144 African American adults aged 60 and older will be recruited.
Gender:
All
Ages:
60 years and above
Trial Updated:
02/15/2024
Locations: Pennington Biomedical Research, Baton Rouge, Louisiana
Conditions: Dementia of Alzheimer Type
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Taletrectinib Phase 2 Global Study in ROS1 Positive NSCLC
NCT04919811
Recruiting
The main purpose of the study is to evaluate safety and efficacy of taletrectinib (also known as AB-106 or DS-6051b) monotherapy in the treatment of advanced NSCLC.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/14/2024
Locations: SCRI - Hematology Oncology Clinic, Baton Rouge, Louisiana
Conditions: Non Small Cell Lung Cancer
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