There are currently 1046 clinical trials in Ann Arbor, Michigan looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Michigan, University of Michigan Comprehensive Cancer Center, University of Michigan Health System and CS Mott Children's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Efficacy and Safety of Lonigutamab in Subjects With Thyroid Eye Disease (TED)
NCT05683496
Recruiting
Phase 1/2, multicenter, multiple dose clinical study designed to evaluate lonigutamab in subjects with TED.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/20/2024
Locations: Clinical Research Site, Ann Arbor, Michigan
Conditions: Thyroid Eye Disease
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Treatment of the Biceps With Concomitant Supraspinatus Tears
NCT05660031
Recruiting
The long head of the biceps (LHB) tendon is thought to be a common source of shoulder pain and dysfunction in patients with rotator cuff pathology. Tenotomy and tenodesis have been shown to produce favourable and comparable results in treating LHB lesions, but a controversy still exists regarding the treatment of choice. Some suggest that tenotomy should be reserved for older, low-demand patients, while tenodesis should be performed in younger patients and those who engage in heavy labor. Propon... Read More
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
03/20/2024
Locations: Sports Medicine and Shoulder Surgery, University of Michigan, Ann Arbor, Michigan
Conditions: Supraspinatus Tear
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A Study of CHeckpoint Inhibitors in Men With prOgressive Metastatic Castrate Resistant Prostate Cancer Characterized by a Mismatch Repair Deficiency or Biallelic CDK12 Inactivation
NCT04104893
Recruiting
The primary objective is to assess the activity and efficacy of pembrolizumab, a checkpoint inhibitor, in Veterans with metastatic castration-resistant prostate cancer (mCRPC) characterized by either mismatch repair deficiency (dMMR) or biallelic inactivation of CDK12 (CDK12-/-). The secondary objectives involve determining the frequency with which dMMR and CDK12-/- occur in this patient population, as well as the effects of pembrolizumab on various clinical endpoints (time to PSA progression, m... Read More
Gender:
Male
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor, Michigan
Conditions: Metastatic Castration Resistant Prostate Cancer
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MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
NCT05933083
Recruiting
Cardiac rehabilitation is a medically recommended program for patients with certain heart conditions. It includes exercise training, health education, and counseling. Unfortunately, many patients do not participate in cardiac rehabilitation. Some find it challenging to attend the in-person sessions. This study aims to compare two methods of delivering cardiac rehabilitation: in-person and through telehealth. The investigators want to know if the effects of these two programs are alike and if cer... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/19/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Myocardial Infarction, Heart Failure, Systolic, Heart Valve Diseases, Angina, Stable, Coronary Artery Disease, Heart Transplant
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Targeting Sleep Homeostasis to Improve Alcohol Use Disorder Treatment Outcomes (M-STAR Study)
NCT04457674
Recruiting
Insomnia is common in people who are in treatment for alcohol use disorder. It can impact both sleep quality and daytime functioning, as well as make it harder to treat the underlying alcohol use disorder. This study is looking at two types of therapy to help manage insomnia specifically for people also in treatment for alcohol use disorder.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/19/2024
Locations: The University of Michigan, Ann Arbor, Michigan
Conditions: Insomnia, Alcohol Use Disorder
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Ultrasound-detectable Endotracheal Tube: a Feasibility Study
NCT05941013
Recruiting
The researchers are studying whether special features make it easier to see if the breathing tube is in the correct place. It is hoped that the investigational device will enable more accurate placement (depth and trachea vs. esophagus).
Gender:
All
Ages:
Between 6 months and 42 months
Trial Updated:
03/19/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Cardiac Catheterization, Endotracheal Tube
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Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty
NCT06234631
Recruiting
The goal of this study is to better understand how daily treatment with cannabidiol (CBD) affects the need for opioid pain medication, as well as pain, inflammation and other related symptoms, after knee replacement surgery. The information collected in this study is necessary to help understand whether CBD may be a useful medication before and/or after surgery. The study hypothesis is that CBD exerts opioid-sparing effects through anti-inflammatory, analgesic, and anxiolytic mechanisms.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/19/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Knee Replacement Surgery, Osteoarthritis, Knee
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Does the Use of a Genomic Tumor Board Increase the Number of Patients Who Receive Genome-Informed Treatment
NCT05455606
Recruiting
This clinical trial studies how well an educationally enhanced genomic tumor board (EGTB) intervention works to increase the number of patients with solid tumors that have come back (recurrent), do not respond to treatment (refractory), have spread to other parts of the body (metastatic), or are newly diagnosed and spread to other parts of the body (advanced) who receive genome-informed treatment. Genome-informed treatment refers to treatment based on the information found in genomic tumor test... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/18/2024
Locations: Saint Joseph Mercy Hospital, Ann Arbor, Michigan
Conditions: Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Refractory Malignant Solid Neoplasm
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Targeting Large-scale Networks in Depression With Real-time Functional Magnetic Resonance Imaging (fMRI) Neurofeedback
NCT06050070
Recruiting
The purpose of this study is to develop a technique called real time fMRI neurofeedback. This technique uses a regular MRI scanner, except that special software allows the researchers to measure activity in participants brain, using fMRI, and then give information, in the form of a feedback signal, which indicates brain activity in real time, while in the MRI scanner. The larger goal of this study is to develop ways to help people, including those with depression, better regulate brain activity... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
03/18/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Major Depressive Disorder
Register for Updates
The Cancer of the Pancreas Screening-5 CAPS5)Study
NCT02000089
Recruiting
Johns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins. The Sub Investigator at each site will be responsible for internal monitoring at their site.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Pancreas Cancer, Peutz-Jeghers Syndrome (PJS), Gene Mutation, Germline Mutation Carrier, Lynch Syndrome
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Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)
NCT05051033
Recruiting
This is a prospective, multicenter, open-label, randomized trial comparing mitral valve (MV) transcatheter edge-to-edge repair (TEER) to surgical repair (1:1 ratio) in patients with primary, degenerative mitral regurgitation (MR). The trial will be conducted in the U.S., Canada, Germany and the United Kingdom, and is designed as a strategy trial. Thus, all devices legally marketed for TEER of primary degenerative MR in a particular country are eligible to be used in this trial.
Gender:
All
Ages:
65 years and above
Trial Updated:
03/14/2024
Locations: University of Michigan Hospital, Ann Arbor, Michigan
Conditions: Mitral Valve Regurgitation
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Prophylactic Reinforcement of Ventral Abdominal Incisions Trial
NCT03911700
Recruiting
This trial is being conducted to evaluate the efficacy of Phasix™ Mesh implantation at the time of midline fascial closure compared to primary suture closure in preventing a subsequent incisional hernia in subjects at risk for incisional hernia after open midline laparotomy surgery.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Open Midline Laparotomy
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