There are currently 378 clinical trials in Grand Rapids, Michigan looking for participants to engage in research studies. Trials are conducted at various facilities, including Spectrum Health at Butterworth Campus, Helen DeVos Children's Hospital at Spectrum Health, CCOP - Grand Rapids and Mercy Health Saint Mary's. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma and ATRT
NCT01356290
Recruiting
Patients with relapsed medulloblastoma, ependymoma and ATRT have a very poor prognosis whether treated with conventional chemotherapy, high-dose chemotherapy with stem cell rescue, irradiation or combinations of these modalities. Antiangiogenetic therapy has emerged as new treatment option in solid malignancies. The frequent, metronomic schedule targets both proliferating tumor cells and endothelial cells, and minimizes toxicity. In this study the investigators will evaluate the use of biweekly... Read More
Gender:
All
Ages:
19 years and below
Trial Updated:
01/27/2024
Locations: Helen DeVos Children's Hospital, Grand Rapids, Michigan
Conditions: Medulloblastoma Recurrent, Ependymoma Recurrent, ATRT Recurrent
Register for Updates
A Prospective Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System foR the tREatment of Vascular Lesions Located in the infrapoplitEal Arteries beLow the Knee (DEEPER REVEAL)
NCT05358353
Recruiting
This is a prospective, multicenter, single arm study designed to evaluate the safety and efficacy of the Temporary Bare Spur Stent System (Spur Stent System).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/26/2024
Locations: Advanced Cardiac and Vascular Centers for Amputation Prevention, Grand Rapids, Michigan
Conditions: Peripheral Arterial Disease, Critical Limb Ischemia
Register for Updates
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
NCT05338697
Recruiting
VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, large-scale, prospective dataset of clinical, transmagnetic stimulation (TMS), and MRI measures in the acute stroke time window.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Corewell Heath Butterworth Hospital, Grand Rapids, Michigan
Conditions: Stroke, Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic
Register for Updates
Study of REGN6569 and Cemiplimab in Adult Patients With Advanced Solid Tumor Malignancies
NCT04465487
Recruiting
There are two main goals of this study: The first is to find the highest safe dose of REGN6569 when given with cemiplimab. The second is to get some initial information about how well the REGN6569 in combination with cemiplimab may help shrink certain types of cancer. The study is also looking at: Side effects that may be experienced by people taking REGN6569 alone and with cemiplimab How REGN6569 and cemiplimab work in the body How much REGN6569 and cemiplimab is in your blood To see if REGN6... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/22/2024
Locations: START South Texas Accelerated Research Therapeutics, Grand Rapids, Michigan
Conditions: Squamous Cell Carcinoma of Head and Neck
Register for Updates
Intra-Corporeal Anastomosis Result in Quicker Return of Bowel Function/Earlier Discharge
NCT03862781
Recruiting
Adult patients who are regularly scheduled to undergo a right hemicolectomy via a minimally invasive approach (robotic or laparoscopic) with the creation of an anastomosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/20/2024
Locations: Spectrum Health Medical Group, Grand Rapids, Michigan
Conditions: Colorectal Disorders
Register for Updates
A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet Syndrome
NCT04572243
Recruiting
The primary purpose of the study is to demonstrate that lorcaserin has superior efficacy compared to placebo on percent change in frequency of convulsive seizures per 28 days in participants with Dravet syndrome.
Gender:
All
Ages:
2 years and above
Trial Updated:
01/18/2024
Locations: Spectrum Health/ Helen DeVos Children's Hospital, Grand Rapids, Michigan
Conditions: Epilepsies, Myoclonic
Register for Updates
A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies
NCT05362773
Recruiting
CP-MGD024-01 is a Phase 1, open-label, multi-center study of MGD024 as a single agent in patients with select blood cancers that have not responded to treatment with standard therapies or who have relapsed after treatment. The study is designed to determine the safety, tolerability, pharmacokinetics (affect of the body on the drug), pharmacodynamic (affect of the drug on the body), immunogenicity (development of antibodies against the drug), and preliminary anti-cancer effect of MGD024. Patient... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/12/2024
Locations: START - Midwest, Grand Rapids, Michigan
Conditions: Leukemia, Acute Myeloid, Myelodysplastic Syndromes, Classical Hodgkin Lymphoma, Leukemia, B-cell, Leukemia, Hairy Cell, Mastocytosis, Aggressive Systemic, Blastic Plasmacytoid Dendritic Cell Neoplasm, Chronic Myeloid Leukemia
Register for Updates
Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine®) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma
NCT05095376
Recruiting
This phase III trial compares the effect of adding lomustine to temozolomide and radiation therapy versus temozolomide and radiation therapy alone in shrinking or stabilizing newly diagnosed MGMT methylated glioblastoma. Chemotherapy drugs, such as lomustine and temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy photons to kill tumor cells and s... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
01/09/2024
Locations: Helen DeVos Children's Hospital at Spectrum Health, Grand Rapids, Michigan +2 locations
Conditions: Glioblastoma, Gliosarcoma
Register for Updates
Hepatic Artery Infusional Floxuridine to Treat Pancreatic Cancer Liver Metastases
NCT03856658
Recruiting
This is a single arm, phase II study without blinding. The purpose is to determine the impact of hepatic artery infusion Floxuridine (FUDR) on liver metastases from pancreatic adenocarcinoma. Patients at Spectrum Health will receive standard of care chemotherapy. They will also receive chemotherapy via surgically placed hepatic artery infusion (HAI) pump.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
01/05/2024
Locations: Spectrum Health, Grand Rapids, Michigan
Conditions: Pancreatic Adenocarcinoma, Liver Metastases
Register for Updates
Roux-en-Y Gastric Bypass Versus Loop Gastrojejunostomy for Malignant Gastric Outlet Obstruction
NCT05986890
Recruiting
This study is intended to investigate whether roux-en-y bypass surgery is superior to conventional loop gastrojejunostomy for Malignant gastric outlet obstruction in terms of tolerance to solid food intake. We hypothesize that roux-en-y bypass will be associated with improved solid food intake in the first 30 days after surgery.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/05/2024
Locations: G. Paul Wright, Grand Rapids, Michigan
Conditions: Malignant Gastric Outlet Obstruction
Register for Updates
Electrocardiogram-based Artificial Intelligence-assisted Detection of Heart Disease
NCT05442203
Recruiting
Atrial fibrillation is an abnormal beating of the heart that can lead to stroke or heart failure. Structural heart diseases are conditions that affect the heart valves or heart muscle and can cause permanent heart damage if left untreated. Sometimes people have atrial fibrillation or structural heart disease and do not know it. The purpose of this study is to evaluate two devices that can predict who has or may develop atrial fibrillation or structural heart disease based on the results of an el... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
01/04/2024
Locations: Corewell Health, Grand Rapids, Michigan
Conditions: Atrial Fibrillation, Structural Heart Disease
Register for Updates
Better Lithotripsy and Ureteroscopy Evaluation of Stenting (BLUES)
NCT05026710
Recruiting
This multi-center trial is being completed to compare patient outcomes related to the Imajin silicone stent in comparison to non-silicone polyurethane stents after ureteroscopy. Eligible participants will be enrolled and randomly assigned to receive the Imajin silicone stent or a non-silicone stent. In addition, the participants will complete questionnaires and have follow-up information collected (approximately 60 days after surgery). The trial hypothesizes that a ureteral stent made of silic... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/22/2023
Locations: Spectrum Health, Grand Rapids, Michigan
Conditions: Renal Stone, Ureteral Stone
Register for Updates