There are currently 477 clinical trials in Kansas City, Missouri looking for participants to engage in research studies. Trials are conducted at various facilities, including Children's Mercy Hospital, Research Medical Center, Saint Luke's Hospital of Kansas City and CCOP - Kansas City. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Quantification of Debris Captured Using TCEP During VIV TAVR With BVF
NCT05093764
Recruiting
The objective of this study is to quantify the amount of debris captured by the SENTINEL transcatheter cerebral embolic protection (TCEP) device in patients undergoing valve in valve transcatheter aortic valve replacement (VIV TAVR) with bioprosthetic valvular fracture (BVF)
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2023
Locations: Saint Luke's Hospital of Kansas City, Kansas City, Missouri
Conditions: Aortic Valve Disease
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The Heart Outcomes in Pregnancy Expectations (H.O.P.E) Registry
NCT04828070
Recruiting
Prospective US registry of pregnant women with cardiac disease to address the substantial gaps in knowledge surrounding these patients, in order to improve future care.
Gender:
Female
Ages:
Between 18 years and 55 years
Trial Updated:
04/10/2023
Locations: Saint Luke's Hospital of Kansas City, Kansas City, Missouri
Conditions: Pregnancy Related, Cardiac Disease
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SHOWME-PAD (Peripheral Artery Disease)
NCT03190382
Recruiting
The overall goal of SHOWME-PAD is to make the existing evidence-base on treatment outcomes -focusing on health status outcomes that reflect the patients' perspective - more transparently available to patients and providers, such that more informed, evidence-based shared treatment decisions occur. INTEGRITY-PAD has the potential to radically reorganize care delivery to patients with PAD such that more value for the patient and society will be created.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/10/2023
Locations: Saint Luke's Hospital of Kansas City, Kansas City, Missouri
Conditions: Peripheral Artery Disease
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Study to Investigate Alternative Dosing Regimens of Belantamab Mafodotin in Participants With Relapsed or Refractory Multiple Myeloma
NCT05064358
Recruiting
This study aims to evaluate alternative dosing regimens of single-agent belantamab mafodotin in participants with relapsed or refractory multiple myeloma (RRMM) to determine if an improved overall benefit/risk profile can be achieved by modifying the belantamab mafodotin dose, schedule, or both.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/10/2023
Locations: GSK Investigational Site, Kansas City, Missouri
Conditions: Multiple Myeloma
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STAR and Deferred Stenting Study
NCT05089864
Recruiting
STAR is a minimal-risk pragmatic clinical trial of patients admitted for a CTO-PCI procedure. The overall objective of the STAR Study is to address the current gaps in knowledge regarding use of STAR during CTO-PCI, as a prospective, multi-center study of 150 participants with randomization of timing of staged PCI. Five sites will be selected to participate in STAR from a national network of highly experienced CTO-PCI centers across the United States.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/10/2023
Locations: Saint Luke's Hospital of Kansas City, Kansas City, Missouri
Conditions: Coronary Occlusion, Coronary Stenosis, Coronary Restenosis
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Study to Evaluate the Reliability, Validity and Safety of Subjective Mobile Refraction
NCT05049070
Recruiting
This study evaluates the reliability, validity and safety of a self administered, subjective refraction test via a mobile medical app (GoEyes) as compared to standard of care subjective manifest refraction performed by a health care provider, in subjects who have no known ocular disease or condition other than refractive error.
Gender:
All
Ages:
Between 18 years and 39 years
Trial Updated:
04/04/2023
Locations: Tauber Eye Center, Kansas City, Missouri
Conditions: Refractive Errors
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An Ascending Dose Comparison of MVT-100 to Definity in Healthy Volunteers
NCT03882359
Recruiting
Definity (perflutren lipid microspheres, Lantheus Medical Imaging) is an ultrasound contrast indicated for use in patients with suboptimal echocardiograms to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border. MVT-100 (the investigational pharmaceutical) is similar to Definity, with the exception of the removal of one lipid in the lipid blend and substitution of another lipid. This study is intended to evaluate the safety and efficacy o... Read More
Gender:
All
Ages:
19 years and above
Trial Updated:
03/30/2023
Locations: Saint Luke's Hospital of Kansas City, Kansas City, Missouri
Conditions: Heart Diseases
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Progression of Gastroesophageal Reflux Disease and Barrett's Esophagus and the Creation of a Barrett's Registry
NCT00574327
Recruiting
The purpose of this study is to determine or evaluate the risk factors such as smoking, family history etc. that cause esophageal cancer and to determine the genetic changes that lead to esophageal cancer. The investigators hypothesis is that systematic collection of data on the natural history of GERD and BE patients and risk factors for development of BE in patients with chronic GERD and progression of BE to dysplasia and adenocarcinoma will provide useful information to develop a decision mod... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/15/2023
Locations: Department of Veterans Affairs Medical Center, Kansas City, Missouri
Conditions: Barrett's Esophagus, Gastroesophageal Reflux Disease, Esophageal Adenocarcinoma
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Barrett's Esophagus Related Neoplasia (BERN) Project
NCT00590239
Recruiting
The use of high resolution endoscopy (HRE), narrow band imaging (NBI) and chromoendoscopy increases the detection rates of Barrett's esophagus (BE) and early neoplasia. Endoscopic mucosal resection (EMR) will improve the accuracy for detection of dysplasia/early neoplasia. Specific Aim 1 - To create a video-atlas of non-dysplastic and dysplastic/early neoplastic lesions in patients with BE. This will be used for training purposes and to assess learning curve associated with these new technologi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/15/2023
Locations: Kansas city VA Medical center, Kansas City, Missouri
Conditions: Barrett's Esophagus, Neoplasms, Gastroesophageal Reflux
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Testing the Use of Targeted Treatment for RET Positive Advanced Non-small Cell Lung Cancer
NCT05364645
Recruiting
This phase II Lung-MAP treatment trial tests whether carboplatin and pemetrexed with or without selpercatinib works to shrink tumors in patients with RET fusion-positive non-small cell lung cancer that is stage IV or has not responded to previous RET directed therapy. Chemotherapy drugs, such as carboplatin and pemetrexed, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Selpercatinib may st... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/28/2023
Locations: Truman Medical Centers, Kansas City, Missouri +1 locations
Conditions: Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
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Prospective Research Assessment in Multiple Myeloma: An Observational Evaluation (PREAMBLE)
NCT01838512
Recruiting
The purpose of this study is to assess the clinical effectiveness of all approved multiple myeloma (MM) therapies in the newly-diagnosed (NDMM) and the relapsed/refractory MM (RRMM) settings in real-world clinical practice.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/16/2023
Locations: Local Institute, Kansas City, Missouri +1 locations
Conditions: Multiple Myeloma
Register for Updates
Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS
NCT05267821
Recruiting
The TRIPS study is a prospective, multi-center, double-blind, adaptively randomized, placebo-controlled clinical trial of the drug anakinra for reversal of moderate to severe hyperinflammation in children with sepsis-induced multiple organ dysfunction syndrome (MODS).
Gender:
All
Ages:
Between 1 day and 17 years
Trial Updated:
02/07/2023
Locations: Mercy Children's Hospital, Kansas City, Missouri
Conditions: Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)
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