There are currently 3072 clinical trials in New York, New York looking for participants to engage in research studies. Trials are conducted at various facilities, including Memorial Sloan Kettering Cancer Center, Columbia University Medical Center, Icahn School of Medicine at Mount Sinai and Columbia University. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Sotagliflozin in Heart Failure With Preserved Ejection Fraction (HFpEF) Patients
NCT05562063
Recruiting
The clinical benefits of the dual Sodium-Glucose cotransporter (SGLT) 1 and 2-inhibition have recently been reported in two clinical trials. The SOLOIST reported the benefits of sotagliflozin in Type-2 Diabetes Mellitus (T2DM) patients hospitalized for worsening of Heart Failure (HF), while the SCORED involved T2DM patients with Chronic Kidney Disease (CKD). It is worth noting that not only did the event curves separate within the first week post-treatment, but the effects of sotagliflozin on HF... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/01/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Heart Failure With Preserved Ejection Fraction
Register for Updates
A Study of Intensity-Modulated Pleural Radiation Therapy (IMPRINT) in People With Thymic Cancer That Has Spread to the Lining of the Lungs and Chest
NCT05354570
Recruiting
The researchers are doing this study to find out whether hemithoracic intensity-modulated pleural radiation therapy (IMPRINT) is a safe treatment that causes few or mild side effects in people with pleural metastases from thymic malignancies. The researchers will also look at whether hemithoracic IMPRINT is effective against participants' cancer.
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
07/01/2024
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Thymic Malignancies, Pleural Metastases
Register for Updates
Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
NCT02201992
Recruiting
This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-sma... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/29/2024
Locations: Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York +3 locations
Conditions: ALK Gene Rearrangement, ALK Gene Translocation, ALK Positive, Stage IB Non-Small Cell Lung Carcinoma AJCC v7, Stage II Non-Small Cell Lung Cancer AJCC v7, Stage IIA Non-Small Cell Lung Carcinoma AJCC v7, Stage IIB Non-Small Cell Lung Carcinoma AJCC v7, Stage IIIA Non-Small Cell Lung Cancer AJCC v7
Register for Updates
Efficacy of STABL Virtual Rehabilitation
NCT05556850
Recruiting
The purpose of the proposed study is to evaluate the efficacy of STABL rehabilitation vs in-person rehabilitation following meniscectomy or synovectomy. STABL is a digital health platform that uses computer-vision technology to facilitate at-home post-op recovery for patients while enabling remote monitoring by their surgeon.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/28/2024
Locations: NYU Langone Health, New York, New York
Conditions: Physical Therapy
Register for Updates
The Impact of Glomerular Disorders on Bone Quality and Strength
NCT04528446
Recruiting
The primary objectives of this study are to: (1) determine the impact of glomerular disease on bone strength and (2) investigate the pathophysiologic underpinnings of impaired bone strength in glomerular disease.
Gender:
ALL
Ages:
Between 5 years and 55 years
Trial Updated:
06/28/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Glomerular Disease, Bone Diseases, Metabolic, Bone Fracture
Register for Updates
Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade Glioma
NCT06108206
Recruiting
The purpose of this study is to find out if performing additional Magnetic Resonance Image (MRI) scans of the subjects' brain during each week of the radiation treatment of their high-grade glioma will help improve the radiation treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/28/2024
Locations: Columbia University Irving Medical Center/NYPH, New York, New York
Conditions: Glioblastoma, Anaplastic Astrocytoma, Astrocytoma, Anaplastic Oligodendroglioma
Register for Updates
Persuasive Health Communication Intervention for HIV/HCV
NCT05968573
Recruiting
A major impediment to emergency department (ED)-based HIV/HCV screening success is that often ED patients at risk for, or later diagnosed with, HIV and HCV decline testing. In this R01 project, the research team will assess how well a promising, easy-to-use, one-time, minimal-training-needed, very brief persuasive health communication intervention (PHCI) increases acceptance of testing among adult ED patients who either currently, formerly or never injected drugs and initially declined HIV/HCV s... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/28/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Human Immunodeficiency Virus (HIV), Hepatitis C (HCV)
Register for Updates
Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients
NCT03546387
Recruiting
The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain development in children who have never had anesthesia.
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
06/28/2024
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Pediatric Retinoblastoma, Retinoblastoma
Register for Updates
Postpartum Low-Dose Aspirin and Preeclampsia
NCT03667326
Recruiting
The purpose of this research study is to find out whether women with severe preeclampsia taking low-dose aspirin (LDA) for 3 weeks post-delivery will experience an improvement in endothelial function (measured as flow-mediated dilation - FMD) and severity of disease, as the effects of preeclampsia can persist postpartum. Women diagnosed with severe preeclampsia prior to delivery will be enrolled and randomized to receive either low-dose aspirin (81mg) or placebo to take daily for up to 3 weeks p... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
06/27/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Preeclampsia Postpartum
Register for Updates
Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders
NCT05982925
Recruiting
In this protocol, a combination of MRI, blood, and cerebrospinal fluid (CSF) analysis will be used to understand the natural history, underlying immunologic mechanisms, and clinical implications of central nervous system (CNS) lesions, in particular lesions in the cerebral cortex, in multiple sclerosis (MS) and other inflammatory and autoimmune disorders affecting the CNS. Patients with these disorders, as well as healthy controls, will undergo baseline clinical evaluation and testing, bloodwork... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/27/2024
Locations: Mount Sinai Hospital, New York, New York
Conditions: Multiple Sclerosis, Neuromyelitis Optica, Demyelinating Autoimmune Diseases, CNS
Register for Updates
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
NCT03053193
Recruiting
The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible for entry into the FLEX Registry, which is intended to enable additional study arms at low incremental effort and cost. FLEX Registry will utilize an adaptive design, where additional targeted substudies and arms can be added after the initial study is opened.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/26/2024
Locations: Kings County Hospital, New York, New York
Conditions: Breast Cancer
Register for Updates
Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis
NCT05451771
Recruiting
The purpose of this study is assess safety, safest dose, and effectiveness of venetoclax in combination with dexamethasone in participants with t(11;14) positive relapsed (comes back) or refractory (did not get better) light chain amyloidosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/26/2024
Locations: New York Presbyterian Hospital/Columbia University Irving Medical Center, New York, New York
Conditions: AL Amyloidosis
Register for Updates