There are currently 3058 clinical trials in New York, New York looking for participants to engage in research studies. Trials are conducted at various facilities, including Memorial Sloan Kettering Cancer Center, Columbia University Medical Center, Icahn School of Medicine at Mount Sinai and Columbia University. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
IMPact on Revascularization Outcomes of IVUS Guided Treatment of Complex Lesions and Economic Impact
NCT04221815
Recruiting
Intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) has been shown in clinical trials, registries, and meta-analyses to reduce recurrent events after PCI. This is accomplished by improving the angiographic result with lesion and vessel assessment to guide stent selection and implantation and intravascular imaging following stent implantation to ensure an adequate treatment endpoint has been achieved. Despite extensive literature supporting the use of IVUS in PCI, util... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/14/2024
Locations: Northwell Health - Lennox Hill Hospital, New York, New York
Conditions: Atherosclerosis
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Study of DF9001 in Patients With Advanced Solid Tumors
NCT05597839
Recruiting
DF9001-001 is a study of a new molecule that targets natural killer (NK) cells and T-cell activation signals to specific receptors on cancer cells. The study will occur in two phases. The first phase will be a dose escalation phase, enrolling patients with various types of solid tumors that express epidermal growth factor receptor (EGFR). The second phase will include a dose expansion using the best dose selected from the first phase of the study. Multiple cohorts will be opened with eligible pa... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Solid Tumor, Adult
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Evaluating Fluid Responsiveness in ICU Patients Using VTI and Trendelenburg Positioning
NCT06418022
Recruiting
Fluid administration is a commonly performed in the ICU for critically ill patients. However, it can lead to complications such as fluid overload, pulmonary edema, and increased mortality in some patients. Therefore, identifying patients who are likely to respond to fluid therapy is crucial for optimizing their management. Several methods have been used to assess fluid responsiveness, such as passive leg raising, stroke volume variation, and cardiac output monitoring. However, these methods have... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Lenox Hill Hospital- Northwell Health, New York, New York
Conditions: Shock, Fluid Overload, Cardiac Output, Low
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Predictors of Aspirin Failure in Preeclampsia Prevention
NCT05709483
Recruiting
Hypertensive disorders of pregnancy (including preeclampsia) are among the leading causes of pregnancy complications and maternal deaths worldwide. They also increase the risks to the babies. Numerous interventions have been suggested in order to reduce the rate of preeclampsia. Low-dose aspirin is the most beneficial prophylactic approach in this regard. Nevertheless, aspirin failure is not uncommon. The genetic, laboratory, and clinical factors associated with low-dose aspirin failure in the p... Read More
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
05/13/2024
Locations: Rockefeller University, New York, New York
Conditions: Preeclampsia
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Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets)
NCT05465044
Recruiting
In this pragmatic clinical trial, which will dovetail with Veterans' routine outpatient dialysis clinic visits in six VA medical centers, the investigators will study 252 Veterans with kidney disease who need to start dialysis treatment. If a Veteran is eligible for the study by making enough residual urine, he/she will have a 50% chance to be offered the usual three-times-per-week dialysis vs. twice-per-week dialysis that is gradually increased to three-times per- week over one year. The invest... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Manhattan Campus of the VA NY Harbor Healthcare System, New York, NY, New York, New York
Conditions: Chronic Kidney Disease (CKD) Stage 5, Kidney Dysfunction Requiring Dialysis (KDRD), Dialysis Dependency
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Targeting the Conus Medullaris With ECAP-Controlled Closed-Loop SCS for Treatment of Chronic Pelvic Pain: HOPE Trial
NCT06413277
Recruiting
The aim of the study is to evaluate the effectiveness of using ECAP (electrically evoked compound action potential)-controlled CL (closed-loop) SCS (spinal cord stimulation) to treat chronic pelvic pain by stimulating an area in the spine called the conus medullaris (the lowermost tapering extremity of the spinal cord).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Ainsworth Institute of Pain Management, New York, New York
Conditions: Chronic Pelvic Pain, Pudendal Neuralgia
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ETE Interventions in the Dental Setting
NCT05584501
Recruiting
The purpose of this study is to use information technology (IT) to support the delivery of HIV prevention and care best practices in the dental care setting to meet the Department of Health and Human Services (DHHS) Ending the HIV Epidemic (ETE) goals.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Columbia University Irving Medical Center / NewYork-Presbyterian Hospital, New York, New York +1 locations
Conditions: HIV Infections
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Assessment of Supportive Care and Educational Needs to Guide Quality Care Improvements for Patients With Locally Advanced and Metastatic Bladder Cancer
NCT06412874
Recruiting
The overall goal of this study is to facilitate care improvements for bladder cancer patients with locally advanced or metastatic disease by designing and evaluating a patient need assessment screening tool to be used, in the future, as standard screening measure. Adult individuals diagnosed with Stage 4 incurable locally advanced or metastatic bladder cancer will be included in this study and asked to participate in a focus group, complete a screening tool, or complete a survey. All data collec... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
05/08/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Screening Tool, Focus Group
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Mother-infant Bonding During COVID-19
NCT04531618
Recruiting
This study will assess whether the promotion of emotional exchange between mother and infant during the first four months of life improves primarily mother-child early relational health (ERH) and secondarily child neurodevelopmental and maternal mental health outcomes. In prior research on preterm infants, a similar intervention demonstrated increased quality of maternal caregiving behaviors and significant improvements in premature infants' neurodevelopment across multiple domains, including so... Read More
Gender:
ALL
Ages:
Between 12 hours and 72 hours
Trial Updated:
05/08/2024
Locations: Morgan Stanley Children's Hospital, New York, New York
Conditions: Child Development, Mother-Infant Interaction, Relation, Parent-Child
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Dentatorubral-pallidoluysian Atrophy Natural History and Biomarkers Study
NCT06273150
Recruiting
DRPLA Natural History and Biomarkers Study (DRPLA NHBS) is a prospective observational study that will lay the foundation for clinical trials in DRPLA. The aims of this project are: * To characterize the natural history of DRPLA in both juvenile- and adult-onset patients and study different modalities of biomarkers in this condition. * To identify genetic factors and biomarkers that could predict disease progression. * To provide a platform to support the design and conduct of clinical trials.... Read More
Gender:
ALL
Ages:
All
Trial Updated:
05/08/2024
Locations: NYU Grossman School of Medicine, New York, New York
Conditions: Dentatorubral-Pallidoluysian Atrophy
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DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.
NCT03718910
Recruiting
DDX3X syndrome is a genetic cause of intellectual disability and other neurologic features including, in some cases, autism. Variants in the DDX3X gene are thought to account for 1-3% of unexplained intellectual disability in females, making it one of the more common causes of intellectual disability.This study seeks to characterize DDX3X-related neurodevelopmental disorders using a number of genetic, medical and neuropsychological measures.
Gender:
ALL
Ages:
2 years and above
Trial Updated:
05/08/2024
Locations: The Seaver Autism Center for Research and Treatment, New York, New York
Conditions: DDX3X, Mental Retardation, X-linked 102, Autism Spectrum Disorder
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PARTNER 3 Trial - Aortic Valve-in-Valve
NCT03003299
Recruiting
This study will assess the safety and effectiveness of the SAPIEN 3/SAPIEN 3 Ultra transcatheter heart valve (THV) in patients with a failing aortic bioprosthetic valve.
Gender:
ALL
Ages:
All
Trial Updated:
05/08/2024
Locations: New York University (NYU) Langone Medical Center, New York, New York +2 locations
Conditions: Aortic Stenosis, Aortic Stenosis, Severe
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