There are currently 3361 clinical trials in New York, New York looking for participants to engage in research studies. Trials are conducted at various facilities, including Memorial Sloan Kettering Cancer Center, Columbia University Medical Center, Icahn School of Medicine at Mount Sinai and Columbia University. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Temsirolimus Alone or Paired With Dexamethasone Delivered to the Adventitia to eNhance Clinical Efficacy After Femoropopliteal Revascularization
NCT03942601
Recruiting
This is a prospective, multi-center, pilot feasibility study to document the effects of adventitial delivery of temsirolimus or temsirolimus with dexamethasone sodium phosphate injection, USP, after revascularization of femoropopliteal lesions in symptomatic patients with moderate to severe claudication (Rutherford 2-3) or critical limb ischemia (CLI) with rest pain (Rutherford 4). Subjects will be followed for up to 60 months post index procedure.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
08/31/2020
Locations: Columbia University Medical Center/NYPH, New York, New York
Conditions: Peripheral Arterial Disease
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Prospective Randomized Controlled Trial Describing the Recurrence Rate of Adenomas in Sessile or Flat Colonic Lesions 15mm or Larger Receiving Post-resection Site Treatment With Snare Tip Soft Coagulation
NCT04063280
Recruiting
A multi-center randomized controlled trial in only 24 patients showed a significant reduction of the recurrence rate by treatment of the normal appearing perimeter of the EMR defect using the argon plasma coagulator (2). A recent non-randomized trial suggested a substantial reduction by treatment of the perimeter with the snare tip in the soft coagulation mode (3).
Gender:
All
Ages:
Between 25 years and 99 years
Trial Updated:
08/07/2020
Locations: NYU Langone Health, New York, New York
Conditions: Colon Polyp
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A Trial of CONvalescent Plasma for Hospitalized Adults With Acute COVID-19 Respiratory Illness
NCT04418518
Recruiting
There is currently no treatment available for COVID-19, the acute respiratory illness caused by the novel SAR-CoV-2. Convalescent plasma from patients who have recovered from COVID-19 that contains antibodies to the virus is a potential therapy. On March 25th, 2020, the FDA approved the use of convalescent plasma under the emergency investigational new drug (eIND) category. Randomized trials are needed to determine the efficacy and safety of COVID-19 convalescent plasma for acute COVID-19 infect... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
07/06/2020
Locations: Weill Cornell Medicine, New York, New York +1 locations
Conditions: COVID-19
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CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant
NCT02061800
Recruiting
The purpose of this study is to learn more about the effects of (classification determinant) CD34+ stem cell selection on graft versus host disease (GVHD) in children, adolescents, and young adults. CD34+ stem cells are the cells that make all the types of blood cells in the body. GVHD is a condition that results from a reaction of transplanted donor T-lymphocytes (a kind of white blood cell) against the recipient's body and organs. Study subjects will be offered treatment involving the use of t... Read More
Gender:
All
Ages:
22 years and below
Trial Updated:
06/17/2020
Locations: Columbia University Medical Center, New York, New York
Conditions: Chronic Myeloid Leukemia (CML), Acute Myelogenous Leukemia (AML), Myelodysplastic Syndrome (MDS), Juvenile Myelomonocytic Leukemia (JMML), Acute Lymphoblastic Leukemia (ALL), Lymphoma (Hodgkin's and Non-Hodgkin's)
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Study of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AML
NCT03258931
Recruiting
A phase III randomized multi-center study designed to compare the efficacy of crenolanib with that of midostaurin when administered following induction chemotherapy, consolidation chemotherapy and bone marrow transplantation in newly diagnosed AML subjects with FLT3 mutation. About 510 subjects will be randomized in a 1:1 ratio to receive either crenolanib in addition to standard first line treatment of AML (chemotherapy and if eligible, transplantation) (arm A) or midostaurin and standard treat... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/21/2020
Locations: New York University, New York, New York +5 locations
Conditions: Newly Diagnosed FLT3 Mutated AML
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Hydroxychloroquine Post Exposure Prophylaxis for Coronavirus Disease (COVID-19)
NCT04318444
Recruiting
The purpose of this study is to test the hypothesis that post-exposure prophylaxis with hydroxychloroquine will reduce the symptomatic secondary attack rate among household contacts of known or suspected COVID-19 patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2020
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: COVID-19, Corona Virus Infection
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Metformin in Heart Failure Without Diabetes
NCT03331861
Recruiting
Columbia University Medical Center is conducting a pilot clinical research study that will assess the use of the medication metformin for heart failure in patients who are not diabetic and have no evidence of insulin resistance. Patients will received either the study drug metformin or placebo for 4 months. During the study, the patients will undergo extensive testing that will include symptom assesment, exercise capacity, echocardiography, cardiac PET imaging and blood tests.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/06/2020
Locations: New York Hospital - Columbia University Irving Medical Center, New York, New York
Conditions: Heart Failure
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Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair
NCT02803957
Recruiting
The objective of this trial is to assess the safety and effectiveness of the study device in subjects with degenerative mitral valve disease receiving a mitral valve repair without cardiopulmonary bypass (treatment group) when compared to subjects receiving mitral valve repair using standard surgical techniques with cardiopulmonary bypass (control group).
Gender:
All
Ages:
21 years and above
Trial Updated:
12/04/2019
Locations: Mount Sinai, Icahn School of Medicine, New York, New York +1 locations
Conditions: Mitral Valve Insufficiency
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Evaluating Alcohol Use in Alcoholic Liver Disease
NCT03267069
Recruiting
This prospective, analytic observational study will investigate alcohol recidivism in patients with alcoholic liver disease. All adult subjects presenting with alcoholic liver disease are considered for inclusion. Subjects able to give consent are included.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/11/2019
Locations: New York Presbyterian Hospital - Weill Cornell Medicine and Columbia University Medical Center, New York, New York
Conditions: Alcoholic Liver Disease
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The Drift-Reduction for Improved FFR Using Fiberoptic Technology (DRIFT) Study
NCT03848650
Recruiting
The primary objective of this study is to assess the accuracy, efficacy, and durability of the OpSens Medical OptoWire Deux pressure wire in the assessment of angiographically intermediate proximal left anterior descending coronary artery (LAD) stenoses in clinical practice.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/19/2019
Locations: New York Presbyterian Hospital/Columbia University Medical Center, New York, New York
Conditions: Left Anterior Descending Coronary Artery Stenosis
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Web Based Investigation of Natural History of Keloid Disorder, an Online Survey
NCT01423981
Recruiting
This trial intends to gather very basic clinical information about keloid, its patterns of presentation, family history, ethnic background and correlation with the type of keloid, as well as prior treatment results that patients have had received.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/03/2016
Locations: Michael H. Tirgan, MD, New York, New York
Conditions: Keloid
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ACTHar in the Treatment of Lupus Nephritis
NCT02226341
Recruiting
Systemic Lupus Erythematosus (SLE) is a disease in which the immune system attacks the healthy cells and tissues, causing inflammation that can damage organs in the body. About 50% of SLE patients experience inflammation in the kidneys. The purpose of this study is to determine the effectiveness and safety of two dosing arms of ACTHar gel in treating proliferative Lupus Nephritis (LN). This study hypothesizes that both dosing arms of ACTHar are safe and effective in treating proliferative LN (Cl... Read More
Gender:
All
Ages:
16 years and above
Trial Updated:
03/17/2016
Locations: Columbia University - Herbert Irving Pavilion, New York, New York
Conditions: Lupus Nephritis
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