The state of North Carolina currently has 16 active clinical trials seeking participants for Healthy research studies. These trials are conducted in various cities, including Durham, Winston-Salem, Charlotte and Chapel Hill.
Intraoperative OCT Guidance of Intraocular Surgery II
NCT03713268
Recruiting
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes. The investigators believe this technology will enable novel ophthalmic and other microsurgeries not possible due to current limitations in surgical visualization.
Gender:
All
Ages:
4 weeks and above
Trial Updated:
06/29/2023
Locations: Duke University Eye Center, Durham, North Carolina
Conditions: Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment, Retinal Disease, Preretinal Fibrosis, Cataract, Ocular Tumor, Strabismus, Healthy
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Physical Activity, Alzheimer's Disease and Cognition Relative to APOE Genotype
NCT03876314
Recruiting
Physical activity and Alzheimer's disease (PAAD-2) is a randomized control trial that will assess the effects of exercise on middle-aged (40-65 years) cognitively normal adults who have a heightened risk of Alzheimer's disease (AD) due to family history (FH+). The investigators will also assess the extent to which this effect is moderated by apolipoprotein epsilon-4 (APOE4) carrier status, and will gather critical new experimental evidence on the use of physical activity to improve cognitive per... Read More
Gender:
All
Ages:
Between 40 years and 65 years
Trial Updated:
05/12/2023
Locations: University of North Carolina-Greensboro, Greensboro, North Carolina
Conditions: Healthy, Dementia, Alzheimer Disease, Physical Activity
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The SKyRoCKeT Study
NCT05770817
Recruiting
The SKyRoCKeT Study (Surface-Knit and Reformulate CADENCE-Kids for Translation) will recruit a sex- and age-balanced sample of 360 young people 6-20 years of age to develop an integrative, physiologically-coherent age-cadence-log(metabolic equivalent, MET) surface-based model, reformulate the prior R21 CADENCE-Kids study (1; NCT01989104) by providing individualized, more precise, age-specific and coherent cadence-intensity thresholds, investigate additional differences by anthropometric factors,... Read More
Gender:
All
Ages:
Between 6 years and 20 years
Trial Updated:
05/02/2023
Locations: University of North Carolina at Charlotte, Charlotte, North Carolina
Conditions: Healthy
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A Biospecimen Collection Study of Leukapheresis-Derived Circulating Tumor Cells, Immune Cells, and Progenitor Cells.
NCT00571389
Recruiting
Primary Objective: This is a study to investigate the feasibility of harvesting, expanding, and selecting T lymphocytes from cancer patients and healthy volunteers. The preliminary objective of this study is aimed at selecting PD-1+ and CTLA4+ T cells and other cellular fractions from peripheral blood of cancer patients and healthy volunteers by using specific conjugated antibodies, evaluating their functional ex vivo anti-tumor cytotoxicity against targeted autologous tumor cells.
Gender:
All
Ages:
5 years and above
Trial Updated:
04/26/2022
Locations: Carolina BioOncology Institute, Huntersville, North Carolina
Conditions: Solid Tumor, Adult, Healthy Donors, COVID-19 Donors
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