The state of North Carolina currently has 29 active clinical trials seeking participants for Type 2 Diabetes research studies. These trials are conducted in various cities, including Durham, Charlotte, Winston-Salem and Chapel Hill.
CardioRenal Effects of SGLT2 Inhibition in Kidney Transplant Recipients
Recruiting
CREST-KT is a single-center, double-blinded, randomized trial of empagliflozin therapy in 72 kidney transplant recipients with (n=36) and without type 2 diabetes (n=36). After evenly dividing patients by type 2 diabetes diagnosis, patients will be randomized 2:1 to empagliflozin 10mg versus placebo.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/05/2025
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Kidney Transplant; Complications, Diabetes Mellitus, Type 2
DIALYSIS-TIR Study
Recruiting
This study will look at control of blood sugar levels in persons with type 2 diabetes mellitus currently on chronic dialysis. Researchers will compare blood sugar levels in people taking semaglutide to people taking "dummy" medicine. The treatment participants get will be decided randomly. Participants will need to inject the study medication once a week. The study will last for 1 year and a month. Participants will be asked to wear a sensor that measures blood sugar levels for a period of 10 d... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2025
Locations: University of North Carolina, Chapel Hill, North Carolina
Conditions: Type 2 Diabetes, End Stage Renal Disease on Dialysis
Food as Medicine for HIV and Diabetes
Recruiting
This is a single-site, open-label, Phase II, community-based randomized controlled explanatory trial to test the efficacy of a medically tailored meal + intensive lifestyle intervention (MTM + ILI) intervention for adults with food insecurity, HIV, and T2DM or high risk of T2DM, compared with a group that receives usual MTM.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: Diabetes Mellitus, Type 2, HIV Infections, PreDiabetes
Addressing Disparities in Diabetes Care
Recruiting
The purpose of this research is to find out if using a continuous glucose monitor and working with a clinical pharmacist can help improve the health of uninsured minority patients with type 2 diabetes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2024
Locations: Atrium Health Myers Park Internal Medicine Clinic, Charlotte, North Carolina
Conditions: Diabetes Mellitus, Type 2
The Diabetes Staging System in Patient Aligned Care Teams
Recruiting
The purpose of this study is to examine the feasibility/acceptability of the Diabetes Staging System (DSS) in Patient Aligned Care Teams (PACT) teams and its ability to increase sodium-glucose cotransporter-2 inhibitor (SGLT2i) and glucagon-like-1 peptide (GLP-1) use in Veteran patients with type 2 diabetes and cardiovascular disease and/or chronic kidney disease.
Gender:
ALL
Ages:
Between 25 years and 75 years
Trial Updated:
04/12/2024
Locations: Greenville VA Health Care Center, 401 Moye Blvd, Greenville, North Carolina
Conditions: Diabetes Mellitus, Type 2 Diabetes