The city of Cincinnati, Ohio, currently has 15 active clinical trials seeking participants for Diabetes research studies.
A Study to Evaluate the Efficacy and Safety of Once-Weekly MET097 in Adults With Obesity or Overweight and T2DM
Recruiting
This study is designed to test how well once-weekly MET097 (an ultra-long-acting GLP-1 receptor agonist) works to treat adults with obesity or overweight and type 2 diabetes mellitus (T2DM) compared to placebo. MET097 or placebo will be administered to individuals via subcutaneous injection once weekly for 28 weeks. If an individual is randomly assigned to MET097 they will receive one of four different dose regimens.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/09/2025
Locations: Research Site 097202-001010, Cincinnati, Ohio
Conditions: Obesity in Diabetes, Type 2 Diabetes Mellitus (T2DM)
Surgical or Medical Treatment
Recruiting
This study will test the hypothesis that metabolic bariatric surgery will be more effective at providing durable glycemic control and reduce co-morbidities than intensive medical therapy in youth with type 2 diabetes.
Gender:
ALL
Ages:
Between 13 years and 19 years
Trial Updated:
02/10/2025
Locations: Cincinnati Childrens, Cincinnati, Ohio
Conditions: Diabetes Mellitus, Type 2, Pediatric Obesity, Bariatric Surgery Candidate
Effect of Fasting on Hypoglycemic Counterregulation in Type 1 Diabetes
Recruiting
Iatrogenic hypoglycemia is still considered to be the number one barrier to effective glycemic control in patients with type 1 diabetes (T1D). In a previous study, it was observed in people without diabetes that fasting can be detrimental to the hormonal and hepatic responses to insulin-induced hypoglycemia. In the experiments described herein, the impact fasting has on hypoglycemic counterregulation in people with T1D will be determined.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
08/29/2024
Locations: University of Cincinnati, Cincinnati, Ohio
Conditions: Hypoglycemia, type1diabetes