The state of Pennsylvania currently has 15 active clinical trials seeking participants for Type 1 Diabetes research studies. These trials are conducted in various cities, including Philadelphia, Pittsburgh, Hershey and Allentown.
Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)
Recruiting
A multi-center, placebo-controlled, double blind, 1:1:1 randomized control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes within 100 days of diagnosis.
Gender:
ALL
Ages:
Between 12 years and 35 years
Trial Updated:
10/17/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Diabetes Mellitus, Type 1
Rituximab-pvvr and Abatacept Vs Rituximab-pvvr Alone in New Onset Type 1 Diabetes
Recruiting
The study is a two-arm, multicenter, double-blinded clinical trial testing sequential therapy with rituximab-pvvr followed by abatacept versus rituximab-pvvr alone in new onset T1D. The primary objective is to test whether the C-peptide response to a 2-hour mixed meal tolerance test, will be improved in participants with new onset T1D who are treated with Abatacept after Rituximab-pvvr compared to those treated with Rituximab-pvvr and placebo 24 months after enrollment.
Gender:
ALL
Ages:
Between 8 years and 45 years
Trial Updated:
09/27/2024
Locations: University of Pittsburg, Pittsburg, Pennsylvania
Conditions: Type 1 Diabetes Mellitus
Pilot Brief Communal Coping Intervention for Adults With Type 1 Diabetes
Recruiting
We plan to develop a communal coping intervention aimed at instilling a shared appraisal of diabetes and increasing patient-partner collaboration. To that end, we will pilot the first randomized clinical trial of a brief communal coping intervention among couples in which one person has T1D
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: Carnegie Mellon University, Pittsburgh, Pennsylvania
Conditions: Diabetes Mellitus, Type 1