There are currently 55 clinical trials in Lancaster, Pennsylvania looking for participants to engage in research studies. Trials are conducted at various facilities, including Lancaster General Hospital, Urological Associates Of Lancaster, Lancaster Urology and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Persona Revision Knee System Outcomes
NCT04821154
Recruiting
The study will evaluate the performance, clinical benefits and safety of the Persona Revision Knee System in patients who have received primary or revision total knee arthroplasty (TKA) treatment. This will be done using a multicenter, single-arm, consecutive series, retrospective cohort study with prospective follow-up.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/27/2023
Locations: Penn Medicine/ Lancaster General Health, Lancaster, Pennsylvania
Conditions: Arthroplasty Complications, Infection, Knee Disease, Knee Osteoarthritis
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Post-approval Study of Transcarotid Artery Revascularization in Standard Risk Patients With Significant Carotid Artery Disease
NCT05365490
Recruiting
The study objective is to evaluate real world usage of the ENROUTE Transcarotid Stent when used with the ENROUTE Transcarotid Neuroprotection System in patients at standard risk for adverse events from carotid endarterectomy
Gender:
All
Ages:
Between 18 years and 79 years
Trial Updated:
11/15/2023
Locations: Lancaster General Hospital, Lancaster, Pennsylvania
Conditions: Carotid Artery Diseases
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Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy
NCT05112237
Recruiting
The objective of this study is to collect information on patients with cardiomyopathy (CM) due to mutations in the MYBPC3 gene, to evaluate their disease course, burden of illness, risk factors for this disease, and the quality of life (QoL). This study will also collect information on treatments, procedures and outcome in infants and children up to 18 yrs who have this mutation.
Gender:
All
Ages:
Between 0 years and 18 years
Trial Updated:
11/13/2023
Locations: Cardiology Care for Children, Lancaster, Pennsylvania
Conditions: Cardiomyopathy
Register for Updates
Adjuvant Treatment Determined By Pathological Response To Neoadjvuant Nivolumab
NCT04013854
Recruiting
Subjects with resectable melanoma will receive neoadjuvant nivolumab followed by surgical resection. Post-operatively, subjects will receive open-label treatment with up to 1 year of adjuvant nivolumab or ipilimumab plus nivolumab as determined by pathologic response at the time of resection.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/10/2023
Locations: Lancaster General Hospital, Lancaster, Pennsylvania
Conditions: Melanoma Stage III, Melanoma
Register for Updates
A Clinical Study to Evaluate Safety and Performance of PEEK-OPTIMA™ HA Enhanced.
NCT04416321
Recruiting
The purpose of this trial is to collect clinical outcomes including radiographic and CT outcomes in patients who undergo spinal fusion using the Keos Lumbar Interbody Fusion Device.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/26/2023
Locations: Neurosurgical Associates of Lancaster, Lancaster, Pennsylvania
Conditions: Degenerative Disc Disease, Spondylolisthesis, Retrolisthesis
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Study of ORIC-944 in Patients With Metastatic Prostate Cancer
NCT05413421
Recruiting
The purpose of this study is to establish recommended Phase 2 dose (RP2D) and/or maximum tolerated dose (MTD) and preliminary antitumor activity of ORIC-944 in patients with metastatic prostate cancer.
Gender:
Male
Ages:
18 years and above
Trial Updated:
04/28/2023
Locations: Keystone Urology Specialists, Lancaster, Pennsylvania
Conditions: Metastatic Prostate Cancer, Neuroendocrine Prostate Cancer
Register for Updates
Consistently Assess Signs and Symptom of Heart Failure
NCT05833581
Recruiting
Heart failure (HF) is a major public health problem. The New York Heart Association (NYHA) Functional Classification by a HF provider helps to guide their decisions in patient treatment. The purpose of this study is to further examine the NYHA Classification Guide that is designed to assist healthcare providers. The investigators will conduct the study in the outpatient clinic setting where adult patients with chronic heart failure are treated. HF providers will be asked to complete the NYHA cla... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
04/17/2023
Locations: Lancaster General Health/Penn Medicine, Lancaster, Pennsylvania
Conditions: Heart Failure, Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction
Register for Updates