The city of Philadelphia, Pennsylvania, currently has 14 active clinical trials seeking participants for Type 2 Diabetes research studies.
Phenotyping Genetic Risk for Type 2 Diabetes
NCT04024631
Recruiting
This study tests the hypothesis that non-diabetic individuals with a high genetic risk score for type 2 diabetes have impaired glucose tolerance and insulin resistance compared to those with a low genetic risk score for type 2 diabetes.
Gender:
ALL
Ages:
Between 10 years and 70 years
Trial Updated:
08/14/2024
Locations: Childrens Hospital of Philadelphia, Philadelphia, Pennsylvania +1 locations
Conditions: Diabetes Mellitus, Type 2, Genetics
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Effects of Sitagliptin in Individuals With Genetically Decreased DPP4
NCT04323189
Recruiting
This is a pilot clinical trial to test the hypothesis that during sitagliptin (DPP4 inhibitor), individuals heterozygous for DPP4 loss of function variants will have a reduction in DPP4 activity and antigen, lower glucose after a mixed meal, and higher levels of intact DPP4 substrates compared to during placebo and compared to matched controls.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/25/2024
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Genetics Disease, Type2 Diabetes, Heart Failure
Register for Updates