There are currently 51 clinical trials in North Charleston, South Carolina looking for participants to engage in research studies. Trials are conducted at various facilities, including Coastal Carolina Research Center, Medical University of South Carolina, National Allergy and Asthma Research, LLC and Novartis Investigative Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Erosive Esophagitis
NCT05587309
Recruiting
The objective of the Healing Phase of the study is to evaluate the safety and efficacy of up to 8 weeks of once daily oral administration of BLI5100 versus a PPI control in healing EE. The objective of the Maintenance Phase of the study is to evaluate the safety and efficacy of 24 weeks of once daily oral administration of BLI5100 (low or high dose) versus a PPI control in the maintenance of healed EE.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/14/2024
Locations: Research Site 61, North Charleston, South Carolina
Conditions: Erosive Esophagitis
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Study of CYR-064 Versus Placebo in Patients.
NCT06019000
Recruiting
Randomized, double-blinded, placebo-controlled trial to determine the safety and efficacy of CYR-064.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/30/2024
Locations: Charleston ENT and Allergy, North Charleston, South Carolina
Conditions: Hyposmia
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Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents
NCT06120491
Recruiting
The intention of the study is to demonstrate superiority of Saruparib (AZD5305) + physician's choice NHA relative to placebo + physician's choice NHA by assessment of radiographic progression-free survival (rPFS) in participants with mCSPC.
Gender:
Male
Ages:
Between 18 years and 130 years
Trial Updated:
04/25/2024
Locations: Research Site, North Charleston, South Carolina
Conditions: Metastatic Castration-Sensitive Prostate Cancer
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A Study to Access the Efficacy and Safety of Solriamfetol in Subjects With ADHD (FOCUS)
NCT05972044
Recruiting
FOCUS (Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol) is a Phase 3, multi-center, randomized, double-blind, placebo-controlled, parallel- group trial to assess the efficacy and safety of solriamfetol in adults with ADHD.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
04/25/2024
Locations: Clinical Research Site, North Charleston, South Carolina
Conditions: ADHD
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A 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR)
NCT04636814
Recruiting
The purpose of this study is to evaluate the efficacy and the safety of two doses of CHF6001 (Tanimilast) as add-on to maintenance triple therapy in the target patient population.
Gender:
All
Ages:
40 years and above
Trial Updated:
04/17/2024
Locations: Chiesi Clinical Trial - Site 840598, North Charleston, South Carolina
Conditions: Chronic Obstructive Pulmonary Disease
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Phase 1b, Open-Label Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of EP262 in Subjects With Chronic Inducible Urticaria
NCT06050928
Recruiting
This phase 1b trial will evaluate the effects of EP262 in subjects with Chronic Inducible Urticaria (CIndU), including symptomatic dermographism and cold urticaria.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/16/2024
Locations: National Allergy and Asthma Research, LLC., North Charleston, South Carolina
Conditions: Chronic Inducible Urticaria
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A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)
NCT04042844
Recruiting
This is a double-blind, saline-controlled, and randomized study with blinded assessments using a single dose. Subjects that have a current diagnosis of chronic lumbar disc disease and meet eligibility criteria will be enrolled. Chronic lumbar disc disease is defined as back and/or radicular pain with degeneration of the disc confirmed by patient history, physical examination, and radiographic measures such as computed tomography (CT), magnetic resonance imaging (MRI), plain film, myelography, di... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
04/15/2024
Locations: Coastal Carolina Research Center, North Charleston, South Carolina
Conditions: Lumbar Disc Disease
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A Study to Investigate the Safety and Immunogenicity of the Quadrivalent Influenza mRNA Vaccines in Adults Aged 18 Years and Above
NCT06361875
Recruiting
The purpose of this study is to evaluate the safety and immunogenicity of a single intramuscular (IM) injection of different formulations of Quadrivalent Influenza Vaccine (QIV) messenger ribonucleic acid (mRNA) (MRT5421, MRT5424, and MRT5429) compared to an active control (QIV- standard dose (SD), QIV- high dose (HD) [adults ≥ 65 years of age only], or quadrivalent recombinant influenza vaccine (RIV4)) in adults 18 years of age and older.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/10/2024
Locations: Coastal Carolina Research Center Site Number : 8400014, North Charleston, South Carolina
Conditions: Influenza Immunization
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Sleep Signal Analysis for Current Major Depressive Episode (SAMDE)
NCT05708222
Recruiting
The objective of this study is to collect data to finalize the development of MEB-001 software as a medical device. The data collected in this study will be used to develop MEB-001 machine learning algorithms by training the algorithms to match the patient's demographic and clinical information, and the objective physiological signals (i.e., electroencephalogram (EEG) and electrocardiogram (ECG)) recorded during PSG with the diagnosis of cMDE performed through the MINI neuropsychiatric evaluatio... Read More
Gender:
All
Ages:
Between 22 years and 75 years
Trial Updated:
04/02/2024
Locations: Medbridge Healthcare, North Charleston, South Carolina
Conditions: Depressive Episode, Depression, Depressive Disorder, Depressive Disorder, Major, Depression Mild
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Study to Evaluate NRCT-101SR in Pediatric Subjects With ADHD
NCT06215144
Recruiting
To evaluate the efficacy and safety of NRCT-101SR compared to placebo in subjects 13-17 years of age with ADHD
Gender:
All
Ages:
Between 13 years and 17 years
Trial Updated:
03/19/2024
Locations: Coastal Carolina Research Center - North Charleston, North Charleston, South Carolina
Conditions: Attention-Deficit/Hyperactivity Disorder (ADHD)
Register for Updates
A Multi-Center, Prospective, Observational Study of Patients Being Treated With ORGOVYX
NCT05467176
Recruiting
This is a multi-center, prospective, observational study of patients being treated with ORGOVYX. The goal of this study is to generate real-world evidence about the safety and effectiveness of ORGOVYX in patients with prostate cancer in routine clinical care and the clinical course during treatment with and following cessation of ORGOVYX.
Gender:
Male
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: Lowcountry Urology Clinics, North Charleston, South Carolina
Conditions: Prostate Cancer
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Phase 3 Efficacy and Safety Laboratory Classroom Study in Pediatrics (6-12) With ADHD Using CTx-1301
NCT05924594
Recruiting
The goal of this clinical trial is to evaluate the efficacy and safety of CTx-1301 in children (6-12) with ADHD in a laboratory classroom setting.
Gender:
All
Ages:
Between 6 years and 12 years
Trial Updated:
01/22/2024
Locations: Coastal Carolina Research Center, North Charleston, South Carolina
Conditions: ADHD, ADHD - Combined Type, Attention Deficit Hyper Activity, Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder With Hyperactivity, Attention Deficit Hyperactivity Disorder Combined, Attention-deficit Hyperactivity
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