There are currently 343 clinical trials in Fort Worth, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including Cook Children's Medical Center, GSK Investigational Site, Cook Children's Medical Center - Fort Worth and UT Southwestern/Simmons Cancer Center-Fort Worth. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
ONC-392 and Pembrolizumab in Platinum Resistant Ovarian Cancer
NCT05446298
Recruiting
This is a study to test the safety and efficacy with the combination of a next generation anti-CTLA-4 antibody, ONC-392, and anti-PD-1 antibody, pembrolizumab, in platinum resistant ovarian cancer patients.
Gender:
Female
Ages:
18 years and above
Trial Updated:
01/05/2024
Locations: Texas Oncology, P.A., Fort Worth - USOR. 420, Fort Worth, Texas
Conditions: Ovarian Cancer, High Grade Serous Adenocarcinoma of Ovary, Primary Peritoneal Carcinoma, Fallopian Tube Cancer
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Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
NCT05102019
Recruiting
To demonstrate the safety and effectiveness of the Reducer system for treatment of patients with refractory angina pectoris treated with maximally tolerated guideline-directed medical therapy who demonstrate objective evidence of reversible myocardial ischemia in the distribution of the left coronary artery and who are deemed unsuitable for revascularization. A non-randomized single-arm will further assess the safety and effectiveness of the Neovasc Reducer System in selected subjects with rever... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/02/2024
Locations: Medical City Fort Worth, Fort Worth, Texas
Conditions: Refractory Angina
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Microcurrent Stimulation Therapy for Nonexudative Age-related Macular Degeneration (i-SIGHT)
NCT05447650
Recruiting
Evaluate the safety and efficacy of transpalpebral microcurrent stimulation (MCS) therapy for patients with nonexudative (dry) age-related macular degeneration (AMD).
Gender:
All
Ages:
50 years and above
Trial Updated:
01/02/2024
Locations: Texas Retina Associates, Fort Worth, Texas
Conditions: Age-Related Macular Degeneration, Dry Age-related Macular Degeneration, Nonexudative Age-related Macular Degeneration
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Saroglitazar Magnesium for the Treatment of Nonalcoholic Steatohepatitis With Fibrosis
NCT05011305
Recruiting
Saroglitazar Magnesium for the Treatment of Nonalcoholic Steatohepatitis
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
12/30/2023
Locations: Zydus US061, Fort Worth, Texas
Conditions: Nonalcoholic Steatohepatitis, Fibrosis
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Study of INCB123667 in Subjects With Advanced Solid Tumors
NCT05238922
Recruiting
This is an open-label, dose-escalation and dose-expansion study to determine the safety, tolerability, PK, pharmacodynamics, and preliminary efficacy of INCB123667 when administered as monotherapy at the RDE(s) in participants with selected advanced or metastatic solid tumors. Part 1A (dose escalation) will determine the recommended dose of INCB123667 for expansion (RDE) and the maximum tolerated dose (MTD). Part 1B (cohort dose expansion phase) will further explore antitumor activity of INCB123... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/26/2023
Locations: Texas Oncology-Fort Worth South Henderson, Fort Worth, Texas
Conditions: Solid Tumors
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Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE)
NCT04873869
Recruiting
The objective of this study is to assess the efficacy, safety, and pharmacokinetics of NBI-921352 as adjunctive therapy for seizures in subjects with SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE).
Gender:
All
Ages:
Between 2 years and 21 years
Trial Updated:
12/21/2023
Locations: Cook Children's Medical Center, Fort Worth, Texas
Conditions: SCN8A Developmental and Epileptic Encephalopathy Syndrome
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MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
NCT03053193
Recruiting
The FLEX Registry will be implemented to operate as a large-scale, population based, prospective registry. All patients with stage I to III breast cancer who receive MammaPrint® and BluePrint testing on a primary breast tumor are eligible for entry into the FLEX Registry, which is intended to enable additional study arms at low incremental effort and cost. FLEX Registry will utilize an adaptive design, where additional targeted substudies and arms can be added after the initial study is opened.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/20/2023
Locations: The Center for Cancer and Blood Disorders, Fort Worth, Texas
Conditions: Breast Cancer
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Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection
NCT04098146
Recruiting
Prospective will be collected in a minimum of 300 patients presenting with an acquired segmental mandibular defect ≥ 4 cm secondary to OSSC removal and who require mandibular reconstruction.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/14/2023
Locations: John Peter Smith Health Network, Fort Worth, Texas
Conditions: Mandibular Reconstruction, Segmental Mandibular Defects
Register for Updates
Childhood Cancer Survivor Study
NCT01120353
Recruiting
The Childhood Cancer Survivor Study (CCSS) will investigate the long-term effects of cancer and its associated therapies. A retrospective cohort study will be conducted through a multi-institutional collaboration, which will involve the identification and active follow-up of a cohort of approximately 50,000 survivors of cancer, diagnosed before 21 years of age, between 1970 and 1999 and 10,000 sibling controls. This project will study children and young adults exposed to specific therapeutic mod... Read More
Gender:
All
Ages:
All
Trial Updated:
12/11/2023
Locations: Cook Children's Medical Center, Fort Worth, Texas
Conditions: Cancer
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Heat Therapy, Functional Capacity, and Vascular Health in Older Adults
NCT05706181
Recruiting
To test the hypothesis that home-based leg heat therapy improves functional capacity, vascular function, and exercise hyperemia in older adults.
Gender:
All
Ages:
Between 55 years and 80 years
Trial Updated:
12/06/2023
Locations: University of North Texas Health Science Center, Fort Worth, Texas
Conditions: Aging Well, Walking, Difficulty, Hyperemia
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Study of Narazaciclib (ON 123300) Plus Letrozole in Endometrial Cancer and Other Gynecologic Malignancies
NCT05705505
Recruiting
This study will assess the safety and efficacy of increasing doses of narazaciclib (ON 123300) in combination with the standard daily dose (2.5mg) of letrozole in patients with Recurrent Metastatic Low-grade Endometrioid Endometrial Cancer and other Gynecologic Malignancies.
Gender:
Female
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: Texas Oncology - Fort Worth Cancer Center, Fort Worth, Texas
Conditions: Endometrioid Endometrial Cancer
Register for Updates
Empowering Students Project
NCT05511298
Recruiting
The Empowering Students Project is an evaluation of the effectiveness of a psychoeducational program for adolescents, intended to help youth build healthy relationship skills while supporting positive socioemotional development and promoting successful transition to young adulthood.
Gender:
All
Ages:
23 years and below
Trial Updated:
11/29/2023
Locations: The Parenting Center, Fort Worth, Texas
Conditions: Relationship, Social
Register for Updates