There are currently 979 clinical trials in San Antonio, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Health Science Center at San Antonio, GSK Investigational Site, Pfizer Investigational Site and Methodist Children's Hospital of South Texas. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors
NCT05277051
Recruiting
This is a first time in-human (FTIH) study designed to investigate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of GSK4381562 in participants with select loco-regionally recurrent solid tumors or metastatic solid tumors where curative or standard treatment options have been exhausted.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/08/2024
Locations: GSK Investigational Site, San Antonio, Texas
Conditions: Neoplasms
Register for Updates
Customized TULSA-PRO Ablation Registry
NCT05001477
Recruiting
This patient registry will capture data from patients who have been or who are undergoing the transurethral ultrasound ablation (TULSA) procedure as part of their routine clinical care. The registry will shed light on real-world outcomes of safety and efficacy of the procedure and understand how a patient's quality of life is affected throughout their follow-up and lifetime.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/05/2024
Locations: Urology Place, San Antonio, Texas
Conditions: Prostate Cancer, Prostate Adenocarcinoma, Benign Prostatic Hyperplasia
Register for Updates
A Study of DCR-STAT3 in Adults With Solid Tumors
NCT06098651
Recruiting
This is a sequential, ascending-dose, multicenter study conducted in patients with refractory solid tumors designed to evaluate the safety, tolerability, and pharmacokinetics of DCR-STAT3.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/04/2024
Locations: Next Oncology, San Antonio, Texas
Conditions: Solid Tumor, Adult, Refractory Tumor
Register for Updates
Safety, Tolerability, and Pharmacokinetics of DCR-PDL1 in Adults With Solid Tumors
NCT06504368
Recruiting
The study will evaluate the safety, tolerability, and pharmacokinetics of intravenous DCR-PDL1 in adults with solid tumors. Participants will be enrolled in one of 4 ascending-dose cohorts. Each treatment cycle will consist of multiple intravenous (IV) doses. Dose escalation decisions will be based on data collected during the dose-limiting toxicity (DLT) period.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/04/2024
Locations: Next Oncology, San Antonio, Texas
Conditions: Solid Tumors, Adult
Register for Updates
Study to Assess Drug Levels and Safety of Golcadomide (BMS-986369) in Healthy Participants and Participants With Different Degrees of Hepatic Impairment
NCT06535399
Recruiting
The purpose of this study is to assess the drug levels and safety of golcadomide (BMS-986369) in adult participants with moderate and severe Hepatic Impairment (HI), and in matched healthy control participants with normal hepatic function.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
11/01/2024
Locations: Local Institution - 0006, San Antonio, Texas +1 locations
Conditions: Hepatic Impairment, Healthy Volunteers
Register for Updates
Evaluate the Safety and Clinical Activity of HH2853
NCT04390737
Recruiting
This is an open-label, multicenter, first-in-human phase I/II study which is composed of 3 parts: phase I dose escalation, phase I dose extension and phase II. HH2853 will be administered orally on a continuous BID schedule on a continuous 28-day treatment cycle.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/30/2024
Locations: NEXT Oncology, San Antonio, Texas
Conditions: Advanced Solid Tumor, FL Lymphoma, Epithelioid Sarcoma, Peripheral T Cell Lymphoma
Register for Updates
Comparing Antipsychotic Medications in LBD Over Time
NCT05590637
Recruiting
The primary objective of this study is to determine whether treatment with pimavanserin or quetiapine is associated with a greater improvement in psychosis when used in a routine clinical setting to treat hallucinations and/or delusions due to Parkinson's disease (PD) or dementia with Lewy bodies (DLB) - collectively referred to as Lewy body disease (LBD).
Gender:
ALL
Ages:
All
Trial Updated:
10/28/2024
Locations: University Health System, San Antonio, Texas +1 locations
Conditions: Parkinson's Disease Psychosis, Dementia With Lewy Bodies
Register for Updates
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
NCT02901184
Recruiting
Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) suggest spironolactone may be effective in HFPEF, but it is generic and will not be studied by industry. SPIRRIT is a unique Registry-Randomized Clinical Trial (RRCT) that will test the hypothesis that spironolactone plus standard of care compared to standard of care alone reduc... Read More
Gender:
ALL
Ages:
Between 50 years and 99 years
Trial Updated:
10/21/2024
Locations: University of Texas Health Science Center at San Antonio, San Antonio, Texas
Conditions: Heart Failure With Preserved Ejection Fraction
Register for Updates
Closed Sinus Augmentation With a Calcium Phosphosilicate Putty
NCT06507709
Recruiting
The goal of this clinical study is to learn if cone beam computed tomography (CBCT) or 3-dimensional x-ray can help to let the investigator know if dental implant placement can be done after performing closed sinus surgery. The study will look at the structure of your gum where the implant will be placed after performing the surgery using 3-D x-ray and compare that to how the structure of your gum looks 6 months later. The 3-D imaging will happen after standard of care surgery to prepare your... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
10/17/2024
Locations: The University of Texas Health Science Center at San Antonio, San Antonio, Texas
Conditions: Dental Implant, Maxillary Sinus Floor Augmentation
Register for Updates
Single and Multiple Ascending Dose Study in Healthy Participants and Participants With an Autoimmune Disease
NCT06488209
Recruiting
The main purpose of this study is to to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity of LAD191 in healthy adults and in adults with an autoimmune disease.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/16/2024
Locations: ICON Early Phase Services, LLC, San Antonio, Texas
Conditions: Healthy Volunteers, Autoimmune Disease
Register for Updates
Prevention of Progression of Prediabetes, Obesity and CV Risk
NCT06446531
Recruiting
The investigators are studying how to help people with prediabetes (Pre-DM) and obesity. The goal is to use new and affordable treatments to bring blood sugar levels back to normal and help participants to lose weight. The investigators also want to reduce participants risk of heart problems. The study team will look at how these treatments affect metabolism and other body functions to help find new ways to treat diabetes and obesity in the future.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: University of Texas Health Science Center at San Antonio, San Antonio, Texas
Conditions: Pre-Diabetes, Weight, Body, Cardiovascular Diseases
Register for Updates
Using SnapshotNIR With Provocative Leg Maneuver for PAD Assessment
NCT06237621
Recruiting
The objective of this trial is to determine if Near-infrared spectroscopy (NIRS) can accurately evaluate the degree of Peripheral Arterial Disease (PAD) during a Provocative Elevation Maneuver of the Lower Extremity (PEMLE) test, as compared to routine clinical assessments.
Gender:
ALL
Ages:
Between 35 years and 99 years
Trial Updated:
10/08/2024
Locations: University of Texas Health Science Center at San Antonio, San Antonio, Texas
Conditions: Peripheral Arterial Disease
Register for Updates