Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors
NCT00003811
Completed
RATIONALE: Chemotherapy drugs use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs such as amifostine may protect normal cells from the side effects of chemotherapy. PURPOSE: Phase I trial to study the effectiveness of high-dose cisplatin, etoposide, and bleomycin plus amifostine in treating children who have malignant germ cell tumors.
Gender:
ALL
Ages:
14 years and below
Trial Updated:
07/03/2013
Locations: Shands Hospital and Clinics, University of Florida, Gainesville, Florida +7 locations
Conditions: Childhood Germ Cell Tumor, Drug/Agent Toxicity by Tissue/Organ, Extragonadal Germ Cell Tumor, Ovarian Cancer
Register for Updates
Cisplatin and Docetaxel With or Without Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Newly Diagnosed Stage III Non-Small Cell Lung Cancer
NCT00113386
Terminated
RATIONALE: Drugs used in chemotherapy, such as cisplatin and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Cisplatin and docetaxel may make tumor cells more sensitive to radiation therapy. Giving more than one drug (combination chemotherapy) together with radiation therapy before surgery may shrink the tumor so it can be removed. Giving chemotherapy... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/21/2013
Locations: Mayo Clinic - Jacksonville, Jacksonville, Florida +3 locations
Conditions: Lung Cancer
Register for Updates
S0227 Cisplatin With Either Paclitaxel or Gemcitabine in Recurrent, Persistent, or Metastatic Cervical Cancer
NCT00057928
Withdrawn
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known whether cisplatin is more effective when combined with paclitaxel or gemcitabine in treating cervical cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of cisplatin combined with paclitaxel to that of cisplatin combined with gemcitabine in treating women who have recurrent, persi... Read More
Gender:
FEMALE
Ages:
All
Trial Updated:
06/11/2012
Locations: Mayo Clinic, Jacksonville, Florida
Conditions: Cervical Cancer
Register for Updates
Etoposide Plus Cisplatin in Treating Patients With Recurrent Ependymomas
NCT00002876
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients with recurrent ependymomas following radiation therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/10/2011
Locations: Mayo Clinic Jacksonville, Jacksonville, Florida
Conditions: Brain and Central Nervous System Tumors
Register for Updates
Cisplatin and Etoposide Prior to Radiation Therapy in Treating Patients With CNS Tumors
NCT00002472
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of cisplatin and etoposide in treating patients with CNS tumors.
Gender:
ALL
Ages:
3 years and above
Trial Updated:
03/14/2011
Locations: Mayo Clinic - Jacksonville, Jacksonville, Florida
Conditions: Brain and Central Nervous System Tumors, Pediatric Germ Cell Tumor, Extragonadal Germ Cell Tumor
Register for Updates
Fludeoxyglucose F18 Positron Emission Tomography Imaging In Assessing Patients Before and After Treatment for Locally Advanced Non-Small Cell Lung Cancer
NCT00083083
Unknown
RATIONALE: Imaging procedures, such as fludeoxyglucose F18 positron emission tomography (\^18FDG-PET), may improve the ability to detect disease progression and help doctors predict a patient's response to treatment and plan more effective treatment. PURPOSE: This phase II trial is studying how well \^18FDG-PET imaging works in detecting disease progression and determining response to treatment in patients who are undergoing chemoradiotherapy for locally advanced non-small cell lung cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/26/2011
Locations: Bethesda Comprehensive Cancer Care Center at Bethesda Memorial Hospital, Boynton Beach, Florida +3 locations
Conditions: Lung Cancer
Register for Updates