Combination Chemotherapy in Treating Patients With Advanced Cancer
NCT00024323
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combining 3-AP with cisplatin in treating patients who have advanced cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2013
Locations: Arizona Clinical Research Center, Tucson, Arizona +1 locations
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
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Combination Chemotherapy Plus Radiation Therapy With or Without Fluorouracil in Treating Patients With Cancer of the Esophagus or Stomach
NCT00009880
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining chemotherapy and radiation therapy may kill more tumor cells. PURPOSE: Randomized phase II trial to compare the effectiveness of combination chemotherapy plus radiation therapy with and without fluorouracil in treating patients who have cancer of the esophagus or stomach.
Gender:
ALL
Ages:
All
Trial Updated:
07/17/2013
Locations: Mobile Infirmary Medical Center, Mobile, Alabama +65 locations
Conditions: Esophageal Cancer, Gastric Cancer
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Cisplatin and Radiation Therapy With or Without Hyperthermia Therapy in Treating Patients With Cervical Cancer
NCT00085631
Terminated
RATIONALE: Drugs used in chemotherapy, such as cisplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Hyperthermia therapy kills tumor cells by heating them to several degrees above body temperature. It is not yet known whether chemotherapy and radiation therapy are more effective with or without hyperthermia therapy in treating cervical cancer. PURPOSE: This randomized phase III trial com... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/10/2013
Locations: Duke Cancer Institute, Durham, North Carolina
Conditions: Cervical Cancer
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Bryostatin-1 Plus Cisplatin in Treating Patients With Recurrent or Advanced Cancer of the Cervix
NCT00005965
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of bryostatin-1 plus cisplatin in treating patients who have recurrent or advanced cancer of the cervix.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/09/2013
Locations: Albert Einstein Comprehensive Cancer Center, Bronx, New York +5 locations
Conditions: Cervical Cancer
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Gemcitabine and Cisplatin in Treating Patients With Metastatic or Recurrent Solid Tumors
NCT00004090
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of gemcitabine and cisplatin in treating patients who have metastatic or recurrent solid tumors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/09/2013
Locations: Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois +1 locations
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
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ONYX-015 With Cisplatin and Fluorouracil in Treating Patients With Advanced Head and Neck Cancer
NCT00006106
Withdrawn
RATIONALE: A specially modified virus called ONYX-015 may be able to kill tumor cells while leaving normal cells undamaged. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining ONYX-015 with chemotherapy may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of ONYX-015 combined with cisplatin and fluorouracil in treating patients who have advanced head and neck cancer.
Gender:
ALL
Ages:
Between 18 years and 79 years
Trial Updated:
07/09/2013
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts +1 locations
Conditions: Lip and Oral Cavity Cancer, Head and Neck Cancer, Oropharyngeal Cancer
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Combination Chemotherapy With or Without G-CSF in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer
NCT00003691
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy consisting of doxorubicin and cisplatin with or without paclitaxel and G-CSF in treating patients who have stage III, stage IV, or recurrent endometrial cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/08/2013
Locations: University of Alabama Comprehensive Cancer Center, Birmingham, Alabama +72 locations
Conditions: Endometrial Cancer
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Surgery With or Without Chemotherapy in Treating Patients With Stage IB Cervical Cancer
NCT00002536
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving chemotherapy drugs before surgery may shrink the tumor so that it can be removed during surgery. PURPOSE: Randomized phase III trial to compare surgery with or without chemotherapy in treating patients who have stage IB cervical cancer.
Gender:
FEMALE
Ages:
All
Trial Updated:
07/08/2013
Locations: University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama +40 locations
Conditions: Cervical Cancer
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7-hydroxystaurosporine and Cisplatin in Treating Patients With Advanced Malignant Solid Tumors
NCT00012194
Terminated
Phase I trial to study the effectiveness of combining UCN-01 with cisplatin in treating patients who have advanced solid tumors. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. UCN-01 may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth and may help cisplatin kill more cancer cells by making tumor cells more sensitive to the drug.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2013
Locations: Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
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Combination Chemotherapy in Treating Patients With Recurrent or Advanced Cancer of the Uterus
NCT00002993
Terminated
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy with mitomycin, doxorubicin, and cisplatin in treating patients with recurrent or advanced cancer of the uterus.
Gender:
FEMALE
Ages:
All
Trial Updated:
07/08/2013
Locations: University of Alabama Comprehensive Cancer Center, Birmingham, Alabama +53 locations
Conditions: Sarcoma
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Radiation Therapy With or Without Cisplatin or Fluorouracil in Treating Patients With Cancer of the Cervix
NCT00003078
Completed
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy and chemotherapy may kill more tumor cells. It is not known whether receiving radiation therapy plus cisplatin is more effective than receiving radiation therapy plus fluorouracil in treating patients with cancer of the cervix. PURPOSE: Randomized phase III trial to compare the effecti... Read More
Gender:
FEMALE
Ages:
All
Trial Updated:
07/08/2013
Locations: University of Alabama Comprehensive Cancer Center, Birmingham, Alabama +65 locations
Conditions: Cervical Cancer
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Combination Chemotherapy With or Without Surgery in Treating Patients With Stage III Ovarian Epithelial Cancer
NCT00002568
Completed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug or combining chemotherapy with surgery may kill more tumor cells. PURPOSE: Randomized phase III trial to compare the effectiveness of combination chemotherapy consisting of paclitaxel and cisplatin with or without surgery in treating patients with stage III ovarian epithelial cancer.
Gender:
FEMALE
Ages:
All
Trial Updated:
07/08/2013
Locations: University of Alabama Comprehensive Cancer Center, Birmingham, Alabama +54 locations
Conditions: Ovarian Cancer
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