Cisplatin Clinical Trials

A collection of 1422 research studies where Cisplatin is the intervention. These studies are located in the United States. Cisplatin is used for conditions such as Head and Neck Cancer, Lung Cancer and Non-small Cell Lung Cancer.

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Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

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* Compensation for time may be available

Featured Trial

Studying an Investigational Virus Vaccine

Recruiting

The main objectives of this study are to assess the safety and effectiveness of an investigational vaccine aimed at preventing norovirus, commonly known as the stomach flu. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.

Conditions:

Healthy

Interested in vaccine studies

All Conditions

Preventative Trials

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Featured Trial

Type 2 Diabetes Clinical Trial

Recruiting

Can changing your breakfast improve your type 2 diabetes? If you have an HbA1C of 7.0% or higher, you are invited to participate in an online study at the University of Michigan.

Conditions:

Type 2 Diabetes

Diabetes Mellitus Type 2 in Obese

Diabetes Type Two

Type 2 Diabetes Mellitus

Diabete Type 2

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Featured Trial

Evaluating an Investigational Treatment for Hidradenitis Suppurativa

Recruiting

The main objectives of this Phase 2 study are to evaluate the safety and effectiveness of an investigational medication in adults with moderate to severe hidradenitis suppurativa (HS), a chronic skin condition. Participants will be randomly assigned to receive the investigational treatment or a placebo. Should you express interest, the research site will contact you directly to provide further details and address any questions you may have about study requirements, risks/benefits, and compensation.

Conditions:

All Conditions

Hidradenitis suppurativa (Skin disorder)

Dermatology

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Dinutuximab, Sargramostim, and Combination Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

NCT03786783

Active Not Recruiting

This phase II pilot trial studies the side effects and how well dinutuximab and sargramostim work when combined with chemotherapy in patients with high-risk neuroblastoma. Immunotherapy with monoclonal antibodies, such as dinutuximab, may induce changes in the body's immune system and may interfere with the ability of tumor cells to grow and spread. Sargramostim helps the body produce normal infection-fighting white blood cells. These cells also help the dinutuximab work better. Giving chemother... Read More

Gender:

ALL

Ages:

30 years and below

Trial Updated:

03/20/2025

Locations: Children's Hospital Los Angeles, Los Angeles, California +9 locations

Conditions: Ganglioneuroblastoma, High Risk Neuroblastoma

Learn More ›

Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)

NCT03924856

Active Not Recruiting

A global study to evaluate peri-operative pembrolizumab with chemotherapy versus placebo to pembrolizumab plus chemotherapy in cisplatin eligible patients.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/20/2025

Locations: Scripps MD Anderson ( Site 0010), La Jolla, California +174 locations

Scripps MD Anderson ( Site 0010), La Jolla, California

Providence Saint John's Health Center ( Site 0075), Santa Monica, California

Georgetown University Medical Center ( Site 0022), Washington, District of Columbia

AdventHealth Orlando-AdventHealth Medical Group Hematology & Oncology at Orlando ( Site 0005), Orlando, Florida

Parkview Cancer Institute ( Site 0077), Fort Wayne, Indiana

Indiana University Melvin and Bren Simon Cancer Center ( Site 0004), Indianapolis, Indiana

Ochsner Medical Center ( Site 0049), New Orleans, Louisiana

New England Cancer Specialists ( Site 0070), Scarborough, Maine

UMass Memorial Medical Center ( Site 0051), Worcester, Massachusetts

Henry Ford Hospital ( Site 0039), Detroit, Michigan

Mercy Hospital Saint Louis ( Site 0064), Saint Louis, Missouri

Morristown Medical Center ( Site 0015), Morristown, New Jersey

UNM Comprehensive Cancer Center-Clinical Research Office ( Site 0045), Albuquerque, New Mexico

New York University Perlmutter Cancer Center ( Site 0008), New York, New York

University Hospitals Cleveland Medical Center ( Site 0038), Cleveland, Ohio

Oklahoma Cancer Specialists and Research Institute, LLC ( Site 0021), Tulsa, Oklahoma

Portland VA Medical Center ( Site 0084), Portland, Oregon

Allegheny General Hospital ( Site 0048), Pittsburgh, Pennsylvania

MD Anderson Cancer Center ( Site 0063), Houston, Texas

Central Texas Veterans Healthcare System ( Site 0057), Temple, Texas

Inova Schar Cancer Institute ( Site 0007), Fairfax, Virginia

Northwest Medical Specialties, PLLC ( Site 0061), Puyallup, Washington

Seattle Cancer Care Alliance/Univ of Washington Medical Center ( Site 0033), Seattle, Washington

Charleston Area Medical Center ( Site 0023), Charles Town, West Virginia

Mid North Coast Cancer Institute ( Site 1256), Port Macquarie, New South Wales

Southside Cancer Care Centre ( Site 1252), Sydney, New South Wales

Cairns Base Hospital ( Site 1257), Cairns, Queensland

Eastern Health ( Site 1255), Box Hill, Victoria

Peninsula Health Frankston Hospital ( Site 1258), Frankston, Victoria

UZ Brussel ( Site 0358), Brussels, Bruxelles-Capitale, Region De

Jessa Ziekenhuis ( Site 0360), Hasselt, Limburg

CHU UCL Namur Site de Godinne ( Site 0354), Yvoir, Namur

O.L.V. Ziekenhuis Aalst ( Site 0356), Aalst, Oost-Vlaanderen

AZ Maria Middelares Gent ( Site 0353), Gent, Oost-Vlaanderen

Tom Baker Cancer Centre ( Site 0100), Calgary, Alberta

Nova Scotia Health Authority ( Site 0109), Halifax, Nova Scotia

Kingston Health Sciences Centre ( Site 0103), Kingston, Ontario

Lakeridge Health ( Site 0104), Oshawa, Ontario

Sunnybrook Research Institute ( Site 0110), Toronto, Ontario

Princess Margaret Cancer Centre ( Site 0107), Toronto, Ontario

CIUSSS de l Est de L Ile de Montreal - Hopital Maisonneuve-Rosemont ( Site 0105), Montreal, Quebec

Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 0, Quebec City, Quebec

Herlev og Gentofte Hospital. ( Site 0402), Herlev, Hovedstaden

Rigshospitalet University Hospital ( Site 0401), Kobenhavn, Hovedstaden

Odense Universitetshospital ( Site 0403), Odense, Syddanmark

CHU de Bordeaux- Hopital Saint Andre ( Site 0456), Bordeaux, Aquitaine

Centre Leon Berard ( Site 0465), Lyon, Auvergne

Centre Francois Baclesse ( Site 0459), Caen, Calvados

Centre Armoricain de Radiotherapie Imagerie medicale et Oncologie ( Site 0457), Plerin, Cotes-d Armor

Hopital Foch ( Site 0483), Suresnes, Hauts-de-Seine

CHU de Montpellier - Hopital Saint-Eloi ( Site 0469), Montpellier, Languedoc-Roussillon

Institut de Cancerologie de l Ouest Site Paul Papin ( Site 0453), Angers, Maine-et-Loire

Hopital Robert Schuman ( Site 0452), Metz, Moselle

Centre Jean Perrin ( Site 0460), Clermont-Ferrand, Puy-de-Dome

Clinique Victor Hugo ( Site 0463), Le Mans, Sarthe

CHU de Rouen ( Site 0493), Rouen, Seine-Maritime

Institut Sainte Catherine ( Site 0454), Avignon, Vaucluse

Klinikum der Eberhard-Karls-Universitaet Tuebingen ( Site 0502), Tuebingen, Baden-Wurttemberg

Universitaetsklinikum Erlangen ( Site 0505), Erlangen, Bayern

Universitaetsklinikum Magdeburg A.o.R. ( Site 0516), Magdeburg, Sachsen-Anhalt

Universitaetsklinikum Carl Gustav Carus ( Site 0519), Dresden, Sachsen

Universitaetsklinikum Schleswig-Holstein-Campus Lubeck ( Site 0512), Luebeck, Schleswig-Holstein

Charite Universitaetsmedizin Berlin ( Site 0515), Berlin, Not set

Vivantes Klinikum am Urban ( Site 0522), Berlin, Not set

Pecsi Tudomanyegyetem AOK ( Site 1009), Pecs, Baranya

SZTE Szent-Gyorgyi Albert Klinikai Kozpont ( Site 1010), Szeged, Csongrad

Jasz Nagykun Szolnok Megyei Hetenyi Geza Korhaz Rendelointezet ( Site 1002), Szolnok, Jasz-Nagykun-Szolnok

Bajcsy Zsilinszki Korhaz es Rendelointezet ( Site 1001), Budapest, Not set

Debreceni Egyetem Klinikai Kozpont ( Site 1006), Debrecen, Not set

Petz Aladar Megyei Oktato Korhaz ( Site 1012), Gyor, Not set

Somogy Megyei Kaposi Mor Oktato Korhaz ( Site 1007), Kaposvar, Not set

Cork University Hospital ( Site 0722), Cork, Not set

Tallaght University Hospital ( Site 0710), Dublin, Not set

University Hospital Waterford ( Site 0723), Waterford, Not set

Ha Emek Medical Center ( Site 0808), Afula, Not set

Soroka Medical Center ( Site 0806), Beer Sheva, Not set

Rambam Health Care Campus-Oncology Division ( Site 0802), Haifa, Not set

Shaare Zedek Medical Center ( Site 0809), Jerusalem, Not set

Hadassah Ein Kerem Medical Center ( Site 0810), Jerusalem, Not set

Meir Medical Center ( Site 0803), Kfar Saba, Not set

Rabin Medical Center ( Site 0804), Petach Tikva, Not set

Sheba Medical Center ( Site 0801), Ramat Gan, Not set

Sourasky Medical Center ( Site 0807), Tel Aviv, Not set

Yitzhak Shamir Medical Center ( Site 0805), Zerifin, Not set

Policlinico Gemelli di Roma ( Site 0558), Roma, Abruzzo

Policlinico di Modena ( Site 0553), Modena, Emilia-Romagna

A.O.U. Policlinico Vittorio Emanuele - Presidio Gaspare Rodolico ( Site 0559), Catania, Not set

Istituto Nazionale Studio e Cura dei Tumori ( Site 0551), Milano, Not set

Istituto Nazionale Per Lo Studio E La Cura Dei Tumori ( Site 0552), Napoli, Not set

Fondazione Salvatore Maugeri IRCCS. ( Site 0554), Pavia, Not set

Azienda Ospedaliera San Camillo Forlanini ( Site 0560), Roma, Not set

Azienda Ospedaliera Santa Maria Terni ( Site 0557), Terni, Not set

Hirosaki University Hospital ( Site 1502), Hirosaki, Aomori

National Cancer Center Hospital East ( Site 1504), Kashiwa, Chiba

Ehime University Hospital ( Site 1508), Toon, Ehime

Sapporo Medical University Hospital ( Site 1501), Sapporo, Hokkaido

University of Tsukuba Hospital ( Site 1503), Tsukuba, Ibaraki

Yokosuka Kyosai Hospital ( Site 1509), Yokosuka, Kanagawa

Nara Medical University Hospital ( Site 1510), Kashihara, Nara

Saitama Medical University International Medical Center ( Site 1505), Hidaka, Saitama

Chiba Cancer Center ( Site 1506), Chiba, Not set

Harasanshin Hospital ( Site 1515), Fukuoka, Not set

Hiroshima City Hiroshima Citizens Hospital ( Site 1513), Hiroshima, Not set

Nagano Municipal Hospital ( Site 1516), Nagano, Not set

Osaka Metropolitan University Hospital ( Site 1512), Osaka, Not set

Tokushima University Hospital ( Site 1514), Tokushima, Not set

Tokyo Medical and Dental University Hospital ( Site 1517), Tokyo, Not set

National Cancer Center ( Site 1354), Goyang-si, Kyonggi-do

Seoul National University Bundang Hospital ( Site 1356), Seongnam-si, Kyonggi-do

Korea University Anam Hospital ( Site 1351), Seoul, Not set

Seoul National University Hospital ( Site 1352), Seoul, Not set

Asan Medical Center ( Site 1355), Seoul, Not set

Samsung Medical Center ( Site 1353), Seoul, Not set

Centro de Urologia Avanzada del Noreste S.A. de C.V. ( Site 0254), Monterrey, Nuevo Leon

Investigacion Biomedica para el Desarrollo de Farmacos S.A. de C.V. ( Site 0300), Aguascalientes, Not set

Centro Estatal de Cancerologia de Chihuahua ( Site 0253), Chihuahua, Not set

Instituto Nacional de Cancerologia ( Site 0256), Tlalpan, Not set

Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego ( Site 1062), Wroclaw, Dolnoslaskie

Centrum Onkologii im.prof. F. Lukaszczyka w Bydgoszczy ( Site 1068), Bydgoszcz, Kujawsko-pomorskie

Europejskie Centrum Zdrowia Otwock ( Site 1057), Otwock, Mazowieckie

Luxmed Onkologia sp. z o. o. ( Site 1051), Warszawa, Mazowieckie

Beskidzkie Centrum Onkologii im. Jana Pawla II ( Site 1060), Bielsko-Biala, Slaskie

Clinic of Bashkortostan State Medical University ( Site 0869), Ufa, Baskortostan, Respublika

Ivanovo Regional Oncology Dispensary ( Site 0852), Ivanovo, Ivanovskaya Oblast

Krasnoyarsk Regional Clinical Oncological Dispensary ( Site 0861), Krasnoyarsk, Krasnoyarskiy Kray

Kursk Regional Clinical Oncology Dispensary ( Site 0854), Kursk, Kurskaya Oblast

FSBI ""United Hospital with Polyclinic"" of the Administrative Department of the President of the Ru, Moscow, Moskva

Central Clinical Hospital with outpatient Clinic ( Site 0856), Moscow, Moskva

Bayandin Murmansk Regional Clinical Hospital ( Site 0859), Murmansk, Murmanskaya Oblast

Volga District Medical Center Federal Medical and Biological Agency ( Site 0857), Nizhny Novgorod, Nizhegorodskaya Oblast

Omsk Clinical Oncology Dispensary ( Site 0865), Omsk, Omskaya Oblast

Leningrad Regional Oncology Center ( Site 0868), Saint Petersburg, Sankt-Peterburg

Clinical Hospital Saint Luka ( Site 0867), St. Petersburg, Sankt-Peterburg

Saratov State Medical University n.a. V.I.Razumovskiy ( Site 0866), Saratov, Saratovskaya Oblast

Hospital San Pedro de Alcantara ( Site 0654), Caceres, Extremadura

H. de Gerona Dr. Josep Trueta ( Site 0651), Girona, Gerona

Hospital Universitario Ramon y Cajal ( Site 0660), Madrid, Madrid, Comunidad De

Hospital Universitario Quiron Madrid ( Site 0657), Pozuelo de Alarcon, Madrid, Comunidad De

Instituto Valenciano de Oncologia - IVO ( Site 0662), Valencia, Valenciana, Comunitat

Hospital del Mar ( Site 0653), Barcelona, Not set

Hospital Universitario San Carlos ( Site 0663), Madrid, Not set

Hospital Universitario La Paz ( Site 0661), Madrid, Not set

Hospital Nuestra Sra. de Valme ( Site 0658), Sevilla, Not set

Laenssjukhuset Ryhov ( Site 1205), Jonkoping, Jonkopings Lan

Akademiska Sjukhuset ( Site 1201), Uppsala, Uppsala Lan

Cancercentrum ( Site 1204), Umea, Vasterbottens Lan

Ramathibodi Hospital. ( Site 1451), Bangkok, Krung Thep Maha Nakhon

Faculty of Medicine Siriraj Hospital ( Site 1452), Bangkok, Krung Thep Maha Nakhon

Maharaj Nakorn Chiangmai Hospital ( Site 1453), Chiang Mai, Not set

Srinagarind Hospital ( Site 1454), Khon Kaen, Not set

Hacettepe Universitesi Tıp Fakultesi ( Site 0911), Ankara, Not set

Istanbul Universitesi Cerrahpasa Tip Fakultesi ( Site 0910), Istanbul, Not set

TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 0906), Istanbul, Not set

Universitesi Pendik Egitim ve Arastirma Hastanesi ( Site 0901), Istanbul, Not set

Necmettin Erbakan Universitesi Meram Tip Fakultesi Hastanesi ( Site 0909), Konya, Not set

Sakarya Universitesi Tip Fakultesi ( Site 0913), Sakarya, Not set

Karadeniz Teknik Universitesi Tip Fakultesi Farabi Hastanesi ( Site 0904), Trabzon, Not set

Cherkasy Regional Oncology Dispensary ( Site 0959), Cherkasy, Cherkaska Oblast

MI Dnipr Regional Clinical Hospital named after I.I. Mechnikov ( Site 0963), Dnipropetrovsk, Dnipropetrovska Oblast

Regional Oncological Hospital ( Site 0956), Dnipro, Dnipropetrovska Oblast

Dnipropetrovsk City Multidiscipline Clinical Hosp. 4 of DRC ( Site 0951), Dnipro, Dnipropetrovska Oblast

Reg. Clinical Center of Urology and Nephrology n.a. V. I. Shapoval ( Site 0969), Kharkiv, Kharkivska Oblast

CNPE "Regional Center of Oncology" ( Site 0958), Kharkiv, Kharkivska Oblast

National Cancer Institute of the MoH of Ukraine ( Site 0962), Kyiv, Kyivska Oblast

Lviv Regional Clinical Hospital ( Site 0955), Lviv, Lvivska Oblast

Lviv State Oncology Regional Treatment and Diagnostic Center ( Site 0967), Lviv, Lvivska Oblast

Kyiv City Clinical Oncology Center ( Site 0960), Kyiv, Not set

Aberdeen Royal Infirmary ( Site 0708), Aberdeen, Aberdeen City

Torbay Hospital ( Site 0704), Torquay, Devon

Kent and Canterbury Hospital ( Site 0709), Canterbury, England

Lister Hospital ( Site 0715), Stevenage, Hertfordshire

The Royal Marsden Foundation Trust ( Site 0702), London, London, City Of

Imperial College Healthcare NHS Trust ( Site 0721), London, London, City Of

Norfolk & Norwich University Hospital NHS Foundation Trust ( Site 0725), Norwich, Norfolk

Royal Cornwall Hospital ( Site 0703), Truro, Not set

Conditions: Bladder Cancer

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MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma

NCT06097728

Recruiting

This is a phase III, randomized, open-label, multicenter, global study to determine the efficacy and safety of Volrustomig (MEDI5752) + Carboplatin + Pemetrexed vs the investigator's choice of platinum + Pemetrexed or Nivolumab + Ipilimumab in participants with unresectable pleural mesothelioma.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/20/2025

Locations: Research Site, Phoenix, Arizona +167 locations

Research Site, Phoenix, Arizona

Research Site, Duarte, California

Research Site, Santa Rosa, California

Research Site, Aurora, Colorado

Research Site, Jacksonville, Florida

Research Site, Atlanta, Georgia

Research Site, Chicago, Illinois

Research Site, Baltimore, Maryland

Research Site, Rochester, Minnesota

Research Site, Saint Louis, Missouri

Research Site, East Brunswick, New Jersey

Research Site, Commack, New York

Research Site, Valhalla, New York

Research Site, Cleveland, Ohio

Research Site, Columbus, Ohio

Research Site, Independence, Ohio

Research Site, Portland, Oregon

Research Site, Philadelphia, Pennsylvania

Research Site, Houston, Texas

Research Site, Fairfax, Virginia

Research Site, Chermside, Not set

Research Site, Clayton, Not set

Research Site, Melbourne, Not set

Research Site, Nedlands, Not set

Research Site, Westmead, Not set

Research Site, Anderlecht, Not set

Research Site, Antwerpen, Not set

Research Site, Gent, Not set

Research Site, Hasselt, Not set

Research Site, Leuven, Not set

Research Site, Sint-Niklaas, Not set

Research Site, Barretos, Not set

Research Site, Fortaleza, Not set

Research Site, Joao Pessoa, Not set

Research Site, Porto Alegre, Not set

Research Site, Rio de Janeiro, Not set

Research Site, Santo Andre, Not set

Research Site, São Paulo, Not set

Research Site, Edmonton, Alberta

Research Site, Hamilton, Ontario

Research Site, London, Ontario

Research Site, Ottawa, Ontario

Research Site, Toronto, Ontario

Research Site, Montreal, Quebec

Research Site, Quebec, Not set

Research Site, Beijing, Not set

Research Site, Changsha, Not set

Research Site, Chengdu, Not set

Research Site, Guangzhou, Not set

Research Site, Hangzhou, Not set

Research Site, Harbin, Not set

Research Site, Kunming, Not set

Research Site, Lanzhou, Not set

Research Site, Nanchang, Not set

Research Site, Ningbo, Not set

Research Site, Shanghai, Not set

Research Site, Shenyang, Not set

Research Site, Taiyuan, Not set

Research Site, Tianjin, Not set

Research Site, Wuhan, Not set

Research Site, Xi'an, Not set

Research Site, Zhengzhou, Not set

Research Site, Aarhus N, Not set

Research Site, Copenhagen, Not set

Research Site, Brest, Not set

Research Site, Creteil Cedex, Not set

Research Site, Le Mans Cedex, Not set

Research Site, Lille, Not set

Research Site, Lyon, Not set

Research Site, Marseille Cedex 20, Not set

Research Site, Montpellier, Not set

Research Site, Paris, Not set

Research Site, Rouen, Not set

Research Site, Saint Herblain, Not set

Research Site, Strasbourg, Not set

Research Site, Toulouse, Not set

Research Site, Berlin, Not set

Research Site, Bochum, Not set

Research Site, Essen, Not set

Research Site, Gauting, Not set

Research Site, Georgsmarienhuette, Not set

Research Site, Hamburg, Not set

Research Site, Heidelberg, Not set

Research Site, Kiel, Not set

Research Site, Köln, Not set

Research Site, Muenster, Not set

Research Site, Alessandria, Not set

Research Site, Bari, Not set

Research Site, Bergamo, Not set

Research Site, Milan, Not set

Research Site, Monza, Not set

Research Site, Orbassano, Not set

Research Site, Padova, Not set

Research Site, Parma, Not set

Research Site, Rozzano, Not set

Research Site, Varese, Not set

Research Site, Amagasaki-shi, Not set

Research Site, Hiroshima-shi, Not set

Research Site, Kitakyushu-shi, Not set

Research Site, Matsuyama-shi, Not set

Research Site, Nagoya-shi, Not set

Research Site, Nishinomiya-shi, Not set

Research Site, Okayama-shi, Not set

Research Site, Osakasayama-shi, Not set

Research Site, Tokyo, Not set

Research Site, Ube-shi, Not set

Research Site, Cheongju-si, Not set

Research Site, Seoul, Not set

Research Site, Amsterdam, Not set

Research Site, Eindhoven, Not set

Research Site, Rotterdam, Not set

Research Site, Lørenskog, Not set

Research Site, Oslo, Not set

Research Site, Bydgoszcz, Not set

Research Site, Bystra, Not set

Research Site, Olsztyn, Not set

Research Site, Poznań, Not set

Research Site, Rzeszów, Not set

Research Site, Warszawa, Not set

Research Site, Amanzimtoti, Not set

Research Site, Cape Town, Not set

Research Site, Johannesburg, Not set

Research Site, Kimberly, Not set

Research Site, Polokwane, Not set

Research Site, Pretoria, Not set

Research Site, Barakaldo, Not set

Research Site, Barcelona, Not set

Research Site, Madrid, Not set

Research Site, Oviedo, Not set

Research Site, Baden, Not set

Research Site, Basel, Not set

Research Site, Bern, Not set

Research Site, Fribourg, Not set

Research Site, St. Gallen, Not set

Research Site, Kaohsiung, Not set

Research Site, Taichung, Not set

Research Site, Tainan City, Not set

Research Site, Taipei, Not set

Research Site, Adana, Not set

Research Site, Ankara, Not set

Research Site, Diyarbakir, Not set

Research Site, Izmir, Not set

Research Site, Cambridge, Not set

Research Site, Cardiff, Wales, Not set

Research Site, Leeds, Not set

Research Site, Leicester, Not set

Research Site, London, Not set

Research Site, Manchester, Not set

Research Site, Middlesborough, Not set

Research Site, Newcastle-upon-Tyne, Not set

Research Site, Portsmouth, Not set

Research Site, Taunton, Not set

Conditions: Unresectable Pleural Mesothelioma

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Targeting Androgen Signaling in Urothelial Cell Carcinoma - Neoadjuvant

NCT05839119

Recruiting

This study is for patients who have bladder cancer that invades into the muscle wall of the bladder. The standard treatment for patients with muscle invasive bladder cancer is to give 4 cycles of chemotherapy with the drugs cisplatin and gemcitabine, then to do an operation to remove the bladder (cystectomy). In this study, the investigators will test participants' bladder cancer to see if their bladder cancer has a receptor for testosterone inside the bladder cancer cells. If it has the testos... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/19/2025

Locations: Lifespan Cancer Institute, Providence, Rhode Island

Conditions: Urothelial Carcinoma Bladder, Androgen Receptor Positive

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Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer

NCT03738228

Active Not Recruiting

This phase I trial studies how well atezolizumab before and/or with standard of care chemoradiotherapy works in immune system activation in patients with stage IB2, II, IIIB, or IVA cervical cancer that has spread to the lymph nodes. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving atezolizumab before and/or with chemoradiotherapy may lower the chance o... Read More

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

03/19/2025

Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama +15 locations

Conditions: Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Stage IB2 Cervical Cancer AJCC v8, Stage II Cervical Cancer AJCC v8, Stage IIA Cervical Cancer AJCC v8, Stage IIA1 Cervical Cancer AJCC v8, Stage IIA2 Cervical Cancer AJCC v8, Stage IIB Cervical Cancer AJCC v8, Stage IIIB Cervical Cancer AJCC v8, Stage IVA Cervical Cancer AJCC v8, Cervical Squamous Cell Carcinoma

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A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanced Liver Cancer

NCT05211323

Active Not Recruiting

This phase II trial compares the effect of adding bevacizumab and atezolizumab to gemcitabine and cisplatin (chemotherapy) versus chemotherapy and atezolizumab in treating patients with liver cancer that cannot be removed by surgery (unresectable) or that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may int... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/19/2025

Locations: Sutter Auburn Faith Hospital, Auburn, California +36 locations

Sutter Auburn Faith Hospital, Auburn, California

Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California

Palo Alto Medical Foundation-Fremont, Fremont, California

Memorial Medical Center, Modesto, California

Palo Alto Medical Foundation-Camino Division, Mountain View, California

Palo Alto Medical Foundation Health Care, Palo Alto, California

Sutter Roseville Medical Center, Roseville, California

Sutter Medical Center Sacramento, Sacramento, California

California Pacific Medical Center-Pacific Campus, San Francisco, California

Palo Alto Medical Foundation-Santa Cruz, Santa Cruz, California

Palo Alto Medical Foundation-Sunnyvale, Sunnyvale, California

Sutter Solano Medical Center/Cancer Center, Vallejo, California

Carle at The Riverfront, Danville, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

Carle Cancer Center, Urbana, Illinois

The Carle Foundation Hospital, Urbana, Illinois

Memorial Hospital of South Bend, South Bend, Indiana

UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny, Iowa

Iowa Methodist Medical Center, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa

Mercy Medical Center - Des Moines, Des Moines, Iowa

Miami Valley Hospital South, Centerville, Ohio

Miami Valley Hospital, Dayton, Ohio

Premier Blood and Cancer Center, Dayton, Ohio

Miami Valley Hospital North, Dayton, Ohio

Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio

Miami Valley Cancer Care and Infusion, Greenville, Ohio

Upper Valley Medical Center, Troy, Ohio

Parkland Memorial Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Fort Worth, Fort Worth, Texas

UT Southwestern Clinical Center at Richardson/Plano, Richardson, Texas

VCU Massey Cancer Center at Stony Point, Richmond, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin

Marshfield Medical Center - Minocqua, Minocqua, Wisconsin

Conditions: Combined Hepatocellular Carcinoma and Cholangiocarcinoma, Stage III Liver Cancer, Stage IV Liver Cancer

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Pembrolizumab Plus Olaparib in LA-HNSCC

NCT05366166

Recruiting

The purpose of this research study is to evaluate the effectiveness of using a combination of pembrolizumab and olaparib when given before and after standard chemoradiation therapy in treating locally advanced head and neck squamous cell carcinoma. Pembrolizumab and olaparib are drugs that are approved for head and neck cancer treatment. However, FDA has not approved the use of these two drugs together in treating head and neck cancer.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/19/2025

Locations: Indiana University Simon Comprehensive Cancer Center, Indianapolis, Indiana +3 locations

Conditions: Squamous Cell Carcinoma of Head and Neck

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BrUOG 355: Nivolumab to Tailored Radiation Therapy With Concomitant Cisplatin in the Treatment of Patients With Cervical Cancer

NCT03527264

Terminated

This research study is a Phase II clinical trial. Phase II clinical trials test the safety and effectiveness of the investigational drug in combination with radiation to learn whether the drug(s) works in treating a specific disease. In this study, researchers are studying three treatment arms, each using standard chemotherapy, with the drug cisplatin and radiation and the drug Nivolumab. Each treatment Arm will test the addition of Nivolumab at a different time point

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

03/19/2025

Locations: Rhode Island Hospital, Providence, Rhode Island +1 locations

Conditions: Cervical Cancer

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Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

NCT03067181

Recruiting

This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is removed. When the germ cell tumor has spread outside of the organ in which it developed, it is considered metastatic. Drugs used in chemotherapy, such as bleomycin, carboplatin, etoposide, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them... Read More

Gender:

ALL

Ages:

All

Trial Updated:

03/18/2025

Locations: Children's Hospital of Alabama, Birmingham, Alabama +619 locations

Children's Hospital of Alabama, Birmingham, Alabama

USA Health Strada Patient Care Center, Mobile, Alabama

Anchorage Associates in Radiation Medicine, Anchorage, Alaska

Anchorage Radiation Therapy Center, Anchorage, Alaska

Alaska Breast Care and Surgery LLC, Anchorage, Alaska

Alaska Oncology and Hematology LLC, Anchorage, Alaska

Alaska Women's Cancer Care, Anchorage, Alaska

Anchorage Oncology Centre, Anchorage, Alaska

Katmai Oncology Group, Anchorage, Alaska

Providence Alaska Medical Center, Anchorage, Alaska

Kingman Regional Medical Center, Kingman, Arizona

Banner Children's at Desert, Mesa, Arizona

Cancer Center at Saint Joseph's, Phoenix, Arizona

Phoenix Childrens Hospital, Phoenix, Arizona

Banner University Medical Center - Tucson, Tucson, Arizona

University of Arizona Cancer Center-North Campus, Tucson, Arizona

CHI Saint Vincent Cancer Center Hot Springs, Hot Springs, Arkansas

Arkansas Children's Hospital, Little Rock, Arkansas

CARTI Cancer Center, Little Rock, Arkansas

University of Arkansas for Medical Sciences, Little Rock, Arkansas

Kaiser Permanente-Anaheim, Anaheim, California

Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande, California

PCR Oncology, Arroyo Grande, California

Kaiser Permanente-Bellflower, Bellflower, California

Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California

Mercy Cancer Center - Carmichael, Carmichael, California

Mercy San Juan Medical Center, Carmichael, California

Kaiser Permanente Downey Medical Center, Downey, California

City of Hope Comprehensive Cancer Center, Duarte, California

Mercy Cancer Center - Elk Grove, Elk Grove, California

Kaiser Permanente-Fontana, Fontana, California

UC San Diego Moores Cancer Center, La Jolla, California

Loma Linda University Medical Center, Loma Linda, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Kaiser Permanente Los Angeles Medical Center, Los Angeles, California

Los Angeles General Medical Center, Los Angeles, California

USC / Norris Comprehensive Cancer Center, Los Angeles, California

Cedars Sinai Medical Center, Los Angeles, California

Mattel Children's Hospital UCLA, Los Angeles, California

UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California

Valley Children's Hospital, Madera, California

Providence Queen of The Valley, Napa, California

USC Norris Oncology/Hematology-Newport Beach, Newport Beach, California

UCSF Benioff Children's Hospital Oakland, Oakland, California

Kaiser Permanente-Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

Stanford Cancer Institute Palo Alto, Palo Alto, California

Mercy Cancer Center - Rocklin, Rocklin, California

Kaiser Permanente-Roseville, Roseville, California

Mercy Cancer Center - Sacramento, Sacramento, California

Sutter Medical Center Sacramento, Sacramento, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Kaiser Permanente-San Diego Mission, San Diego, California

Rady Children's Hospital - San Diego, San Diego, California

Naval Medical Center -San Diego, San Diego, California

UCSF Medical Center-Mission Bay, San Francisco, California

Pacific Central Coast Health Center-San Luis Obispo, San Luis Obispo, California

Kaiser Permanente Medical Center - Santa Clara, Santa Clara, California

Mission Hope Medical Oncology - Santa Maria, Santa Maria, California

Providence Medical Foundation - Santa Rosa, Santa Rosa, California

Providence Santa Rosa Memorial Hospital, Santa Rosa, California

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California

Woodland Memorial Hospital, Woodland, California

Children's Hospital Colorado, Aurora, Colorado

UCHealth University of Colorado Hospital, Aurora, Colorado

Penrose-Saint Francis Healthcare, Colorado Springs, Colorado

Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado

UCHealth Memorial Hospital Central, Colorado Springs, Colorado

Memorial Hospital North, Colorado Springs, Colorado

Saint Francis Cancer Center, Colorado Springs, Colorado

AdventHealth Porter, Denver, Colorado

Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado

Mercy Medical Center, Durango, Colorado

Southwest Oncology PC, Durango, Colorado

Poudre Valley Hospital, Fort Collins, Colorado

Cancer Care and Hematology-Fort Collins, Fort Collins, Colorado

Mountain Blue Cancer Care Center, Golden, Colorado

UCHealth Greeley Hospital, Greeley, Colorado

Rocky Mountain Cancer Centers-Lakewood, Lakewood, Colorado

Saint Anthony Hospital, Lakewood, Colorado

Littleton Adventist Hospital, Littleton, Colorado

UCHealth Lone Tree Health Center, Lone Tree, Colorado

Longmont United Hospital, Longmont, Colorado

Rocky Mountain Cancer Centers-Longmont, Longmont, Colorado

Medical Center of the Rockies, Loveland, Colorado

Parker Adventist Hospital, Parker, Colorado

Rocky Mountain Cancer Centers-Parker, Parker, Colorado

Saint Mary Corwin Medical Center, Pueblo, Colorado

Rocky Mountain Cancer Centers - Pueblo, Pueblo, Colorado

Rocky Mountain Cancer Centers-Thornton, Thornton, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

Kaiser Permanente-Capitol Hill Medical Center, Washington, District of Columbia

MedStar Georgetown University Hospital, Washington, District of Columbia

Children's National Medical Center, Washington, District of Columbia

Broward Health Medical Center, Fort Lauderdale, Florida

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Nicklaus Children's Hospital, Miami, Florida

Miami Cancer Institute, Miami, Florida

AdventHealth Orlando, Orlando, Florida

Arnold Palmer Hospital for Children, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Nemours Children's Clinic - Pensacola, Pensacola, Florida

Sacred Heart Hospital, Pensacola, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Tampa General Hospital, Tampa, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Medical Center, West Palm Beach, Florida

Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia

Augusta University Medical Center, Augusta, Georgia

Atrium Health Navicent, Macon, Georgia

Memorial Health University Medical Center, Savannah, Georgia

Straub Clinic and Hospital, Honolulu, Hawaii

Kaiser Permanente Moanalua Medical Center, Honolulu, Hawaii

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii

Tripler Army Medical Center, Honolulu, Hawaii

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho

Saint Luke's Cancer Institute - Meridian, Meridian, Idaho

Saint Luke's Cancer Institute - Nampa, Nampa, Idaho

Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho

Rush - Copley Medical Center, Aurora, Illinois

Illinois CancerCare-Bloomington, Bloomington, Illinois

Illinois CancerCare-Canton, Canton, Illinois

Memorial Hospital of Carbondale, Carbondale, Illinois

SIH Cancer Institute, Carterville, Illinois

Illinois CancerCare-Carthage, Carthage, Illinois

Centralia Oncology Clinic, Centralia, Illinois

Lurie Children's Hospital-Chicago, Chicago, Illinois

John H Stroger Jr Hospital of Cook County, Chicago, Illinois

Rush University Medical Center, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Carle at The Riverfront, Danville, Illinois

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois

Decatur Memorial Hospital, Decatur, Illinois

Illinois CancerCare-Dixon, Dixon, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Crossroads Cancer Center, Effingham, Illinois

Illinois CancerCare-Eureka, Eureka, Illinois

NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois

Illinois CancerCare-Galesburg, Galesburg, Illinois

Western Illinois Cancer Treatment Center, Galesburg, Illinois

NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois

NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois

Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois

Illinois CancerCare-Macomb, Macomb, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

Loyola University Medical Center, Maywood, Illinois

Cancer Care Center of O'Fallon, O'Fallon, Illinois

HSHS Saint Elizabeth's Hospital, O'Fallon, Illinois

Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois

Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois

Advocate Children's Hospital-Park Ridge, Park Ridge, Illinois

Illinois CancerCare-Pekin, Pekin, Illinois

OSF Saint Francis Radiation Oncology at Pekin, Pekin, Illinois

Illinois CancerCare-Peoria, Peoria, Illinois

OSF Saint Francis Radiation Oncology at Peoria Cancer Center, Peoria, Illinois

Methodist Medical Center of Illinois, Peoria, Illinois

OSF Saint Francis Medical Center, Peoria, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Illinois CancerCare-Peru, Peru, Illinois

Valley Radiation Oncology, Peru, Illinois

Illinois CancerCare-Princeton, Princeton, Illinois

North Shore Medical Center, Skokie, Illinois

Saint John's Hospital, Springfield, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Springfield Clinic, Springfield, Illinois

Springfield Memorial Hospital, Springfield, Illinois

Southwest Illinois Health Services LLP, Swansea, Illinois

Carle Cancer Center, Urbana, Illinois

The Carle Foundation Hospital, Urbana, Illinois

Illinois CancerCare - Washington, Washington, Illinois

Rush-Copley Healthcare Center, Yorkville, Illinois

IU Health North Hospital, Carmel, Indiana

Deaconess Clinic Downtown, Evansville, Indiana

Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana

Riley Hospital for Children, Indianapolis, Indiana

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana

Chancellor Center for Oncology, Newburgh, Indiana

Memorial Hospital of South Bend, South Bend, Indiana

UI Health Care Mission Cancer and Blood - Ankeny Clinic, Ankeny, Iowa

Mercy Cancer Center-West Lakes, Clive, Iowa

UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive, Iowa

Alegent Health Mercy Hospital, Council Bluffs, Iowa

Greater Regional Medical Center, Creston, Iowa

Blank Children's Hospital, Des Moines, Iowa

Iowa Methodist Medical Center, Des Moines, Iowa

Mercy Medical Center - Des Moines, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines, Iowa

Iowa Lutheran Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

Mercy Medical Center-West Lakes, West Des Moines, Iowa

Wesley Medical Center, Wichita, Kansas

Flaget Memorial Hospital, Bardstown, Kentucky

Commonwealth Cancer Center-Corbin, Corbin, Kentucky

Saint Joseph Hospital, Lexington, Kentucky

Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky

Saint Joseph Hospital East, Lexington, Kentucky

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Saint Joseph London, London, Kentucky

Jewish Hospital, Louisville, Kentucky

Norton Children's Hospital, Louisville, Kentucky

Saints Mary and Elizabeth Hospital, Louisville, Kentucky

UofL Health Medical Center Northeast, Louisville, Kentucky

Saint Joseph Mount Sterling, Mount Sterling, Kentucky

Jewish Hospital Medical Center South, Shepherdsville, Kentucky

Children's Hospital New Orleans, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Lafayette Family Cancer Center-EMMC, Brewer, Maine

Maine Medical Center-Bramhall Campus, Portland, Maine

Maine Children's Cancer Program, Scarborough, Maine

Maine Medical Center- Scarborough Campus, Scarborough, Maine

University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Tufts Children's Hospital, Boston, Massachusetts

Tufts Medical Center, Boston, Massachusetts

Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

Baystate Medical Center, Springfield, Massachusetts

UMass Memorial Medical Center - University Campus, Worcester, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

Bronson Battle Creek, Battle Creek, Michigan

Children's Hospital of Michigan, Detroit, Michigan

Henry Ford Health Saint John Hospital, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

OSF Saint Francis Hospital and Medical Group, Escanaba, Michigan

Hurley Medical Center, Flint, Michigan

Corewell Health Grand Rapids Hospitals - Butterworth Hospital, Grand Rapids, Michigan

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan

Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

West Michigan Cancer Center, Kalamazoo, Michigan

Ascension Borgess Hospital, Kalamazoo, Michigan

Trinity Health Muskegon Hospital, Muskegon, Michigan

Corewell Health Lakeland Hospitals - Niles Hospital, Niles, Michigan

Lake Huron Medical Center, Port Huron, Michigan

Corewell Health Reed City Hospital, Reed City, Michigan

Corewell Health Children's, Royal Oak, Michigan

Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center, Saint Joseph, Michigan

Corewell Health Lakeland Hospitals - Saint Joseph Hospital, Saint Joseph, Michigan

Munson Medical Center, Traverse City, Michigan

University of Michigan Health - West, Wyoming, Michigan

Essentia Health Cancer Center, Duluth, Minnesota

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

Parkland Health Center-Bonne Terre, Bonne Terre, Missouri

Saint Francis Medical Center, Cape Girardeau, Missouri

Southeast Cancer Center, Cape Girardeau, Missouri

Parkland Health Center - Farmington, Farmington, Missouri

MU Health Care Goldschmidt Cancer Center, Jefferson City, Missouri

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Lake Regional Hospital, Osage Beach, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Missouri Baptist Medical Center, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri

Missouri Baptist Sullivan Hospital, Sullivan, Missouri

BJC Outpatient Center at Sunset Hills, Sunset Hills, Missouri

Saint Patrick Hospital - Community Hospital, Missoula, Montana

Nebraska Cancer Specialists/Oncology Hematology West PC, Grand Island, Nebraska

Nebraska Medicine Heartland Hematology Oncology, Kearney, Nebraska

CHI Health Good Samaritan, Kearney, Nebraska

Saint Elizabeth Regional Medical Center, Lincoln, Nebraska

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

Alegent Health Immanuel Medical Center, Omaha, Nebraska

Hematology and Oncology Consultants PC, Omaha, Nebraska

Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska

Alegent Health Lakeside Hospital, Omaha, Nebraska

Creighton University Medical Center, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Midlands Community Hospital, Papillion, Nebraska

Carson Tahoe Regional Medical Center, Carson City, Nevada

Cancer and Blood Specialists-Henderson, Henderson, Nevada

Comprehensive Cancer Centers of Nevada - Henderson, Henderson, Nevada

Comprehensive Cancer Centers of Nevada-Horizon Ridge, Henderson, Nevada

Las Vegas Cancer Center-Henderson, Henderson, Nevada

OptumCare Cancer Care at Seven Hills, Henderson, Nevada

Comprehensive Cancer Centers of Nevada-Southeast Henderson, Henderson, Nevada

Las Vegas Urology - Green Valley, Henderson, Nevada

Las Vegas Urology - Pebble, Henderson, Nevada

Urology Specialists of Nevada - Green Valley, Henderson, Nevada

Las Vegas Urology - Pecos, Las Vegas, Nevada

Desert West Surgery, Las Vegas, Nevada

OptumCare Cancer Care at Charleston, Las Vegas, Nevada

University Medical Center of Southern Nevada, Las Vegas, Nevada

Hope Cancer Care of Nevada, Las Vegas, Nevada

Cancer and Blood Specialists-Shadow, Las Vegas, Nevada

Radiation Oncology Centers of Nevada Central, Las Vegas, Nevada

Urology Specialists of Nevada - Central, Las Vegas, Nevada

Women's Cancer Center of Nevada, Las Vegas, Nevada

Sunrise Hospital and Medical Center, Las Vegas, Nevada

Las Vegas Urology - Sunset, Las Vegas, Nevada

Urology Specialists of Nevada - Southwest, Las Vegas, Nevada

Radiation Oncology Centers of Nevada Southeast, Las Vegas, Nevada

Cancer Therapy and Integrative Medicine, Las Vegas, Nevada

Ann M Wierman MD LTD, Las Vegas, Nevada

Cancer and Blood Specialists-Tenaya, Las Vegas, Nevada

Comprehensive Cancer Centers of Nevada - Northwest, Las Vegas, Nevada

Las Vegas Urology - Cathedral Rock, Las Vegas, Nevada

Las Vegas Urology - Smoke Ranch, Las Vegas, Nevada

OptumCare Cancer Care at MountainView, Las Vegas, Nevada

Urology Specialists of Nevada - Northwest, Las Vegas, Nevada

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

Comprehensive Cancer Centers of Nevada - Town Center, Las Vegas, Nevada

Comprehensive Cancer Centers of Nevada-Summerlin, Las Vegas, Nevada

Summerlin Hospital Medical Center, Las Vegas, Nevada

Las Vegas Cancer Center-Medical Center, Las Vegas, Nevada

Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada

OptumCare Cancer Care at Fort Apache, Las Vegas, Nevada

Comprehensive Cancer Centers of Nevada - Central Valley, Las Vegas, Nevada

University Cancer Center, Las Vegas, Nevada

Hope Cancer Care of Nevada-Pahrump, Pahrump, Nevada

Renown Regional Medical Center, Reno, Nevada

Saint Mary's Regional Medical Center, Reno, Nevada

Radiation Oncology Associates, Reno, Nevada

Cancer Care Specialists - Reno, Reno, Nevada

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Morristown Medical Center, Morristown, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center-Einstein Campus, Bronx, New York

Montefiore Medical Center-Weiler Hospital, Bronx, New York

Children's Hospital at Montefiore, Bronx, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Maimonides Medical Center, Brooklyn, New York

Roswell Park Cancer Institute, Buffalo, New York

Glens Falls Hospital, Glens Falls, New York

NYU Langone Hospital - Long Island, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

Mount Sinai Hospital, New York, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

New York Medical College, Valhalla, New York

Westchester Medical Center, Valhalla, New York

Mission Hospital, Asheville, North Carolina

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Oncology Specialists of Charlotte, Charlotte, North Carolina

Southern Oncology Specialists-Charlotte, Charlotte, North Carolina

Southeastern Medical Oncology Center-Clinton, Clinton, North Carolina

Duke University Medical Center, Durham, North Carolina

Southeastern Medical Oncology Center-Goldsboro, Goldsboro, North Carolina

Wayne Memorial Hospital, Goldsboro, North Carolina

East Carolina University, Greenville, North Carolina

Novant Health Cancer Institute - Huntersville, Huntersville, North Carolina

Southern Oncology Specialists-Huntersville, Huntersville, North Carolina

Southeastern Medical Oncology Center-Jacksonville, Jacksonville, North Carolina

Matthews Radiation Oncology Center, Matthews, North Carolina

Novant Health Cancer Institute - Matthews, Matthews, North Carolina

Novant Health Cancer Institute - Mooresville, Mooresville, North Carolina

Novant Health Cancer Institute - Rowan, Salisbury, North Carolina

Rowan Regional Medical Center, Salisbury, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Strecker Cancer Center-Belpre, Belpre, Ohio

Adena Regional Medical Center, Chillicothe, Ohio

Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Bethesda North Hospital, Cincinnati, Ohio

TriHealth Cancer Institute-Westside, Cincinnati, Ohio

TriHealth Cancer Institute-Anderson, Cincinnati, Ohio

Case Western Reserve University, Cleveland, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Mount Carmel East Hospital, Columbus, Ohio

Columbus Oncology and Hematology Associates Inc, Columbus, Ohio

Riverside Methodist Hospital, Columbus, Ohio

Grant Medical Center, Columbus, Ohio

The Mark H Zangmeister Center, Columbus, Ohio

Mount Carmel Health Center West, Columbus, Ohio

Doctors Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

Delaware Health Center-Grady Cancer Center, Delaware, Ohio

Grady Memorial Hospital, Delaware, Ohio

Columbus Oncology and Hematology Associates, Dublin, Ohio

Dublin Methodist Hospital, Dublin, Ohio

Mount Carmel Grove City Hospital, Grove City, Ohio

Saint Rita's Medical Center, Lima, Ohio

OhioHealth Mansfield Hospital, Mansfield, Ohio

Marietta Memorial Hospital, Marietta, Ohio

OhioHealth Marion General Hospital, Marion, Ohio

Memorial Hospital, Marysville, Ohio

Knox Community Hospital, Mount Vernon, Ohio

Licking Memorial Hospital, Newark, Ohio

Mercy Health - Perrysburg Hospital, Perrysburg, Ohio

OhioHealth Pickerington Methodist Hospital, Pickerington, Ohio

Southern Ohio Medical Center, Portsmouth, Ohio

ProMedica Flower Hospital, Sylvania, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

Mercy Health - Saint Vincent Hospital, Toledo, Ohio

Mercy Health - Saint Anne Hospital, Toledo, Ohio

Saint Ann's Hospital, Westerville, Ohio

OhioHealth Westerville Medical Campus/Westerville Cancer Center, Westerville, Ohio

Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center, Wilmington, Ohio

Genesis Healthcare System Cancer Care Center, Zanesville, Ohio

Cancer Centers of Southwest Oklahoma Research, Lawton, Oklahoma

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Saint Charles Health System, Bend, Oregon

Clackamas Radiation Oncology Center, Clackamas, Oregon

Providence Cancer Institute Clackamas Clinic, Clackamas, Oregon

Bay Area Hospital, Coos Bay, Oregon

Asante Rogue Regional Medical Center, Medford, Oregon

Providence Newberg Medical Center, Newberg, Oregon

Providence Willamette Falls Medical Center, Oregon City, Oregon

Providence Portland Medical Center, Portland, Oregon

Providence Saint Vincent Medical Center, Portland, Oregon

Legacy Emanuel Children's Hospital, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Jefferson Abington Hospital, Abington, Pennsylvania

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

UPMC-Magee Womens Hospital, Pittsburgh, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania

UPMC-Passavant Hospital, Pittsburgh, Pennsylvania

Asplundh Cancer Pavilion, Willow Grove, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Richland Hospital, Columbia, South Carolina

Gibbs Cancer Center-Gaffney, Gaffney, South Carolina

Saint Francis Hospital, Greenville, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Prisma Health Cancer Institute - Butternut, Greenville, South Carolina

Prisma Health Cancer Institute - Faris, Greenville, South Carolina

Prisma Health Greenville Memorial Hospital, Greenville, South Carolina

Saint Francis Cancer Center, Greenville, South Carolina

Prisma Health Cancer Institute - Eastside, Greenville, South Carolina

Prisma Health Cancer Institute - Greer, Greer, South Carolina

Gibbs Cancer Center-Pelham, Greer, South Carolina

Prisma Health Cancer Institute - Seneca, Seneca, South Carolina

North Grove Medical Park, Spartanburg, South Carolina

Spartanburg Medical Center, Spartanburg, South Carolina

Spartanburg Medical Center - Mary Black Campus, Spartanburg, South Carolina

MGC Hematology Oncology-Union, Union, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

T C Thompson Children's Hospital, Chattanooga, Tennessee

Memorial Hospital, Chattanooga, Tennessee

Pulmonary Medicine Center of Chattanooga-Hixson, Hixson, Tennessee

East Tennessee Childrens Hospital, Knoxville, Tennessee

Saint Jude Children's Research Hospital, Memphis, Tennessee

The Children's Hospital at TriStar Centennial, Nashville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Memorial GYN Plus, Ooltewah, Tennessee

Texas Tech University Health Sciences Center-Amarillo, Amarillo, Texas

The Don and Sybil Harrington Cancer Center, Amarillo, Texas

Dell Children's Medical Center of Central Texas, Austin, Texas

Saint Joseph Regional Cancer Center, Bryan, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

Parkland Memorial Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

El Paso Children's Hospital, El Paso, Texas

Texas Tech University Health Sciences Center-El Paso, El Paso, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

M D Anderson Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

UMC Cancer Center / UMC Health System, Lubbock, Texas

Texas Tech University Health Sciences Center-Lubbock, Lubbock, Texas

Children's Hospital of San Antonio, San Antonio, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University Hospital, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Scott and White Memorial Hospital, Temple, Texas

Primary Children's Hospital, Salt Lake City, Utah

Central Vermont Medical Center/National Life Cancer Treatment, Berlin, Vermont

University of Vermont Medical Center, Burlington, Vermont

University of Vermont and State Agricultural College, Burlington, Vermont

University of Virginia Cancer Center, Charlottesville, Virginia

Children's Hospital of The King's Daughters, Norfolk, Virginia

Naval Medical Center - Portsmouth, Portsmouth, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Carilion Children's, Roanoke, Virginia

Providence Regional Cancer System-Aberdeen, Aberdeen, Washington

Overlake Medical Center, Bellevue, Washington

PeaceHealth Saint Joseph Medical Center, Bellingham, Washington

Highline Medical Center-Main Campus, Burien, Washington

Providence Regional Cancer System-Centralia, Centralia, Washington

Swedish Cancer Institute-Edmonds, Edmonds, Washington

Saint Elizabeth Hospital, Enumclaw, Washington

Providence Regional Cancer Partnership, Everett, Washington

Saint Francis Hospital, Federal Way, Washington

Swedish Cancer Institute-Issaquah, Issaquah, Washington

Kadlec Clinic Hematology and Oncology, Kennewick, Washington

Providence Regional Cancer System-Lacey, Lacey, Washington

Saint Clare Hospital, Lakewood, Washington

PeaceHealth Saint John Medical Center, Longview, Washington

Harrison HealthPartners Hematology and Oncology-Poulsbo, Poulsbo, Washington

Pacific Gynecology Specialists, Seattle, Washington

Seattle Children's Hospital, Seattle, Washington

Swedish Medical Center-Ballard Campus, Seattle, Washington

Kaiser Permanente Washington, Seattle, Washington

Swedish Medical Center-Cherry Hill, Seattle, Washington

Swedish Medical Center-First Hill, Seattle, Washington

Providence Regional Cancer System-Shelton, Shelton, Washington

Saint Michael Cancer Center, Silverdale, Washington

MultiCare Deaconess Cancer and Blood Specialty Center - Valley, Spokane Valley, Washington

MultiCare Deaconess Cancer and Blood Specialty Center - Downtown, Spokane, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

MultiCare Deaconess Cancer and Blood Specialty Center - North, Spokane, Washington

Franciscan Research Center-Northwest Medical Plaza, Tacoma, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Northwest Medical Specialties PLLC, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

PeaceHealth Southwest Medical Center, Vancouver, Washington

Providence Saint Mary Regional Cancer Center, Walla Walla, Washington

North Star Lodge Cancer Center at Yakima Valley Memorial Hospital, Yakima, Washington

Providence Regional Cancer System-Yelm, Yelm, Washington

United Hospital Center, Bridgeport, West Virginia

West Virginia University Charleston Division, Charleston, West Virginia

WVUH-Berkely Medical Center, Martinsburg, West Virginia

West Virginia University Healthcare, Morgantown, West Virginia

Camden Clark Medical Center, Parkersburg, West Virginia

Green Bay Oncology at Saint Vincent Hospital, Green Bay, Wisconsin

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin

Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin

University of Wisconsin Carbone Cancer Center - Johnson Creek, Johnson Creek, Wisconsin

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Holy Family Memorial Hospital, Manitowoc, Wisconsin

Saint Vincent Hospital Cancer Center at Marinette, Marinette, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Children's Hospital of Wisconsin, Milwaukee, Wisconsin

Saint Vincent Hospital Cancer Center at Oconto Falls, Oconto Falls, Wisconsin

HSHS Saint Nicholas Hospital, Sheboygan, Wisconsin

Saint Vincent Hospital Cancer Center at Sturgeon Bay, Sturgeon Bay, Wisconsin

John Hunter Children's Hospital, Hunter Regional Mail Centre, New South Wales

Sydney Children's Hospital, Randwick, New South Wales

The Children's Hospital at Westmead, Westmead, New South Wales

Queensland Children's Hospital, South Brisbane, Queensland

Monash Medical Center-Clayton Campus, Clayton, Victoria

Royal Children's Hospital, Parkville, Victoria

Princess Margaret Hospital for Children, Perth, Western Australia

Perth Children's Hospital, Perth, Western Australia

Alberta Children's Hospital, Calgary, Alberta

University of Alberta Hospital, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Janeway Child Health Centre, Saint John's, Newfoundland and Labrador

IWK Health Centre, Halifax, Nova Scotia

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario

Kingston Health Sciences Centre, Kingston, Ontario

Children's Hospital, London, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Odette Cancer Centre- Sunnybrook Health Sciences Centre, Toronto, Ontario

Hospital for Sick Children, Toronto, Ontario

University Health Network-Princess Margaret Hospital, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec

CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Quebec, Not set

Tata Memorial Hospital, Mumbai, Not set

Tohoku University School of Medicine, Sendai, Aoba-ku

Chiba University, Chiba-sgi, Chiba

Niigata Cancer Centre, Niigata, Chuo-ku

Kyushu Univeristy, Higashi-ku, Fukuoka

Hokkaido University Hospital, Sapporo, Hokkaido

Hyogo Prefectural Kobe Children's Hospital, Kobe, Hyogo

University of Tsukuba Hospital, Tsukuba, Ibaraki

Kanagawa Children's Medical Center, Yokohama, Kanagawa

Saitama Children's Medical Center, Chuo-ku, Saitama

Keio University, Shinjuku-ku, Tokyo

Hiroshima University Hospital, Hiroshima City, Not set

Kyoto Perfectural University of Medicine, Kyoto, Not set

Hyogo College of Medicine, Nishinomiya, Hyogo, Not set

Osaka City General Hospital, Osaka City, Not set

Saitama Medical University International Medical Center, Saitama, Not set

National Cancer Center Hospital, Tokyo, Not set

Kokuritsu Seiiku Medical Research Center Hospital, Tokyo, Not set

Starship Children's Hospital, Grafton, Auckland

Christchurch Hospital, Christchurch, Not set

HIMA San Pablo Oncologic Hospital, Caguas, Not set

San Jorge Children's Hospital, San Juan, Not set

King Faisal Specialist Hospital and Research Centre, Riyadh, Not set

Sheffield Children's Hospital, Broomhall, England

Addenbrookes Hospital-Medical School, Cambridge, England

Saint Bartholomew's Hospital, London, England

University College London Hospitals NHS Trust - Foley Street, London, England

Royal Manchester Children Hospital, Manchester, England

Freeman Hospital, Newcastle Upon Tyne, England

Royal Victoria Infirmary, Newcastle, England

John Radcliffe Hospital, Oxford, England

Weston Park Hospital, Sheffield, England

Saint James's University Hospital, West Yorkshire, England

Western General Hospital, Edinburgh, Scotland

Royal Hospital for Children and Young People, Edinburgh, Scotland

Beatson Oncology Center, Glasgow, Scotland

Royal Hospital for Children, Glasgow, Scotland

Leeds General Infirmary, West Yorkshire, Not set

Conditions: Childhood Extracranial Germ Cell Tumor, Extragonadal Embryonal Carcinoma, Germ Cell Tumor, Malignant Germ Cell Tumor, Malignant Ovarian Teratoma, Stage I Ovarian Choriocarcinoma, Stage I Ovarian Embryonal Carcinoma AJCC v6 and v7, Stage I Ovarian Teratoma AJCC v6 and v7, Stage I Ovarian Yolk Sac Tumor AJCC v6 and v7, Stage I Testicular Choriocarcinoma AJCC v6 and v7, Stage I Testicular Embryonal Carcinoma AJCC v6 and v7, Stage I Testicular Yolk Sac Tumor AJCC v6 and v7, Stage II Ovarian Choriocarcinoma, Stage II Ovarian Embryonal Carcinoma AJCC v6 and v7, Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7, Stage II Testicular Choriocarcinoma AJCC v6 and v7, Stage II Testicular Embryonal Carcinoma AJCC v6 and v7, Stage II Testicular Yolk Sac Tumor AJCC v6 and v7, Stage III Ovarian Choriocarcinoma, Stage III Ovarian Embryonal Carcinoma AJCC v6 and v7, Stage III Ovarian Yolk Sac Tumor AJCC v6 and v7, Stage III Testicular Choriocarcinoma AJCC v6 and v7, Stage III Testicular Embryonal Carcinoma AJCC v6 and v7, Stage III Testicular Yolk Sac Tumor AJCC v6 and v7, Stage IV Ovarian Choriocarcinoma, Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7, Stage IV Ovarian Yolk Sac Tumor AJCC v6 and v7, Testicular Mixed Choriocarcinoma and Embryonal Carcinoma, Testicular Mixed Choriocarcinoma and Teratoma, Testicular Mixed Choriocarcinoma and Yolk Sac Tumor, Stage I Testicular Seminoma AJCC v6 and v7

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A Novel Approach for Alleviating the Side Effects of Chemotherapeutic Agents.

NCT05137067

Completed

This study will assess the effectiveness of a natural nutraceutical in treating the known side effects of chemotherapeutic agents in cancer patients.

Gender:

ALL

Ages:

Between 25 years and 75 years

Trial Updated:

03/18/2025

Locations: Optimal Health Research, Salt Lake City, Utah

Conditions: Breast Cancer, Lung Cancer, Prostate Cancer

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

NCT03126916

Active Not Recruiting

This phase III trial studies iobenguane I-131 or lorlatinib and standard therapy in treating younger patients with newly-diagnosed high-risk neuroblastoma or ganglioneuroblastoma. Radioactive drugs, such as iobenguane I-131, may carry radiation directly to tumor cells and not harm normal cells. Lorlatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving iobenguane I-131 or lorlatinib and standard therapy may work better compared to lorlatinib and... Read More

Gender:

ALL

Ages:

Between 365 days and 30 years

Trial Updated:

03/18/2025

Locations: Children's Hospital of Alabama, Birmingham, Alabama +160 locations

Children's Hospital of Alabama, Birmingham, Alabama

Phoenix Childrens Hospital, Phoenix, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

Kaiser Permanente Downey Medical Center, Downey, California

Loma Linda University Medical Center, Loma Linda, California

Children's Hospital Los Angeles, Los Angeles, California

Mattel Children's Hospital UCLA, Los Angeles, California

Valley Children's Hospital, Madera, California

Kaiser Permanente-Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Rady Children's Hospital - San Diego, San Diego, California

Naval Medical Center -San Diego, San Diego, California

UCSF Medical Center-Mission Bay, San Francisco, California

Children's Hospital Colorado, Aurora, Colorado

Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

Children's National Medical Center, Washington, District of Columbia

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida

Nicklaus Children's Hospital, Miami, Florida

AdventHealth Orlando, Orlando, Florida

Nemours Children's Hospital, Orlando, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Saint Mary's Medical Center, West Palm Beach, Florida

Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia

Memorial Health University Medical Center, Savannah, Georgia

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Advocate Children's Hospital-Oak Lawn, Oak Lawn, Illinois

Advocate Children's Hospital-Park Ridge, Park Ridge, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Children's Hospital New Orleans, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Maine Children's Cancer Program, Scarborough, Maine

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Tufts Children's Hospital, Boston, Massachusetts

Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Dana-Farber Cancer Institute, Boston, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Children's Hospital of Michigan, Detroit, Michigan

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

Henry Ford Health Saint John Hospital, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Corewell Health Children's, Royal Oak, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

University of Missouri Children's Hospital, Columbia, Missouri

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

University Medical Center of Southern Nevada, Las Vegas, Nevada

Sunrise Hospital and Medical Center, Las Vegas, Nevada

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

Summerlin Hospital Medical Center, Las Vegas, Nevada

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Morristown Medical Center, Morristown, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Newark Beth Israel Medical Center, Newark, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Maimonides Medical Center, Brooklyn, New York

Roswell Park Cancer Institute, Buffalo, New York

NYU Langone Hospital - Long Island, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

New York Medical College, Valhalla, New York

Mission Hospital, Asheville, North Carolina

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Duke University Medical Center, Durham, North Carolina

East Carolina University, Greenville, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Richland Hospital, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

East Tennessee Childrens Hospital, Knoxville, Tennessee

Saint Jude Children's Research Hospital, Memphis, Tennessee

The Children's Hospital at TriStar Centennial, Nashville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

El Paso Children's Hospital, El Paso, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

UMC Cancer Center / UMC Health System, Lubbock, Texas

Children's Hospital of San Antonio, San Antonio, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Vermont and State Agricultural College, Burlington, Vermont

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

West Virginia University Healthcare, Morgantown, West Virginia

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Children's Hospital of Wisconsin, Milwaukee, Wisconsin

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

Janeway Child Health Centre, Saint John's, Newfoundland and Labrador

IWK Health Centre, Halifax, Nova Scotia

McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario

Kingston Health Sciences Centre, Kingston, Ontario

Children's Hospital, London, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hospital for Sick Children, Toronto, Ontario

HIMA San Pablo Oncologic Hospital, Caguas, Not set

Conditions: Ganglioneuroblastoma, Neuroblastoma

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Genomic and Methylation Markers in SCLC and LCNEC for Chemo-Immunotherapy Resistance Prediction (STRATUS)

NCT06717243

Recruiting

The goal of this observational study is to understand how genomic and epigenetic factors contribute to resistance against chemo-immunotherapy in adults diagnosed with extensive-stage small cell lung cancer (ES-SCLC) or metastatic large cell neuroendocrine carcinoma (LCNEC). Both ES-SCLC and LCNEC are aggressive forms of lung cancer with limited treatment options and poor prognosis. While initial responses to chemo-immunotherapy are often promising, most patients develop resistance within a few months, resulting in disease progression and limited survival. This study seeks to explore the molecular and cellular changes that drive resistance, providing insights that could guide more personalized and effective treatment strategies in the future. The study focuses on identifying genomic and methylation signatures, as well as analyzing circulating tumor cells (CTCs) and tumor DNA (ctDNA), to better understand the mechanisms of resistance. By collecting and analyzing these biomarkers over time, researchers aim to identify patterns that distinguish patients who benefit long-term from therapy from those who experience early resistance. These findings may pave the way for new diagnostic tools and therapies to predict and overcome resistance to chemo-immunotherapy. The main questions this study seeks to answer are: Are there specific genomic or methylation patterns that predict resistance to chemo-immunotherapy in ES-SCLC and LCNEC? How are circulating tumor cells (CTCs) and tumor DNA (ctDNA) associated with disease progression, treatment response, and survival? What molecular differences exist between patients who respond long-term and those who develop resistance early in their treatment? Participants will: Provide blood and tumor tissue samples before treatment to establish baseline molecular profiles. Undergo follow-up visits every 9 weeks during treatment, where additional blood samples and imaging tests will be collected to monitor disease progression and treatment response. Optionally provide tissue samples through re-biopsy if the disease progresses, enabling researchers to compare changes in tumor biology over time. All blood and tissue samples will be de-identified and securely stored for genomic and epigenetic analyses. Blood samples will be examined for circulating tumor cells and tumor DNA, while tumor tissue samples will undergo in-depth genomic and methylation profiling. Researchers will use advanced molecular and bioinformatics techniques to uncover specific patterns associated with resistance, aiming to improve current treatment strategies and develop more precise therapies. The study will analyze data from patients over three years, encompassing various stages of treatment and disease progression. By examining longitudinal samples, the study aims to capture the dynamic changes that occur in the tumor microenvironment and how these relate to treatment outcomes. This research is particularly important because current treatment options for ES-SCLC and LCNEC are limited, and there are no established methods to predict which patients will respond to chemo-immunotherapy. Identifying biomarkers of resistance could transform clinical care, allowing oncologists to tailor treatments to individual patients' molecular profiles and improve survival outcomes. Ultimately, the findings from this study could lead to the development of new biomarkers for resistance, improve early detection of treatment failure, and provide the foundation for novel therapies targeting resistant cancer cells. By addressing a critical gap in the understanding of resistance mechanisms, the STRATUS trial has the potential to significantly advance the field of personalized oncology. Read Less

Gender:

ALL

Ages:

Between 18 years and 85 years

Trial Updated:

03/18/2025

Locations: Icahn School of Medicine at Mount Sinai, New York, New York +1 locations

Conditions: Small Cell Lung Cancer, Large Cell Neuroendocrine (NE) Tumors, Treatment Failure, Biomarkers / Blood, Biomarkers, Immunotherapy

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