Cisplatin Treatment Options

A collection of 1441 research studies where Cisplatin is the interventional treatment. These studies are located in the United States . Cisplatin is used for conditions such as Head and Neck Cancer, Lung Cancer and Non-Small Cell Lung Cancer.

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Featured Trial

Healthy Participants Needed (Colonoscopy + Cancer Screening)

Recruiting

Earn $325 - $475 in electronic payment card compensation for your time and effort by participating in a clinical study to develop a blood test that may one day help screen for colon cancer. Take a quick quiz to see if you qualify.

Conditions:

Healthy

Healthy Volunteers

Healthy Subjects

Healthy Volunteer

Healthy Participants

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Recruiting

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Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

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Featured Trial

Stroke Clinical Study

Recruiting

A clinical study for people that suffer with Stroke

Conditions:

Stroke

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Featured Trial

Chronic Kidney Disease (CKD) Clinical Study

Recruiting

A clinical study for people that suffer with Chronic Kidney Disease (CKD)

Conditions:

Chronic Kidney Disease (CKD)

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Gemcitabine, Cisplatin, and Nab-Paclitaxel Before Surgery in Patients With High-Risk Liver Bile Duct Cancer

NCT03579771

Completed

This phase II trial studies how well gemcitabine, cisplatin, and nab-paclitaxel work before surgery in treating participants with high-risk bile duct cancer in the liver (intrahepatic cholangiocarcinoma). Drugs used in chemotherapy, such as nab-paclitaxel, cisplatin, and gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving combination chemotherapy before surgery may make the... Read More

Gender:

ALL

Ages:

19 years and above

Trial Updated:

07/30/2025

Locations: Emory University Hospital Midtown, Atlanta, Georgia +6 locations

Conditions: Resectable Cholangiocarcinoma, Stage IB Intrahepatic Cholangiocarcinoma AJCC v8, Stage II Intrahepatic Cholangiocarcinoma AJCC v8, Stage III Intrahepatic Cholangiocarcinoma AJCC v8, Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8, Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8

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Study of Pembrolizumab With Maintenance Olaparib or Maintenance Pemetrexed in First-line (1L) Metastatic Nonsquamous Non-Small-Cell Lung Cancer (NSCLC) (MK-7339-006, KEYLYNK-006)

NCT03976323

Active Not Recruiting

The current study will compare pembrolizumab (MK-3475) plus maintenance olaparib, versus (vs) pembrolizumab plus maintenance pemetrexed for the treatment of non-squamous NSCLC. The study's 2 primary hypotheses are: 1. Pembrolizumab plus maintenance olaparib is superior to pembrolizumab plus maintenance pemetrexed with respect to progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors version 1.1 (RECIST 1.1) by blinded independent clinical review (BICR) and 2. Pembrolizu... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/30/2025

Locations: Alabama Oncology Bruno Cancer Center ( Site 0001), Birmingham, Alabama +177 locations

Alabama Oncology Bruno Cancer Center ( Site 0001), Birmingham, Alabama

Northwest Alabama Cancer Center, PC ( Site 0002), Muscle Shoals, Alabama

Disney Family Cancer Center ( Site 0005), Burbank, California

Boca Raton Regional Hospital ( Site 0018), Boca Raton, Florida

Mid-Florida Cancer Centers ( Site 0022), Orange City, Florida

Moffitt Cancer Center ( Site 0024), Tampa, Florida

Columbus Regional Research Institute ( Site 0098), Columbus, Georgia

Mount Sinai Hospital Medical Center ( Site 0032), Chicago, Illinois

Oncology of Northshore ( Site 0033), Rolling Meadows, Illinois

Methodists Hospitals/Premier Oncology Hematology Associates ( Site 0036), Merrillville, Indiana

Medstar Good Samaritan Hospital ( Site 0040), Baltimore, Maryland

Barbara Ann Karmanos Cancer Institute ( Site 0041), Detroit, Michigan

Hattiesburg Clinic ( Site 0045), Hattiesburg, Mississippi

Frontier Oncology ( Site 0080), Billings, Montana

Bozeman Health Deaconness Cancer Center ( Site 0046), Bozeman, Montana

Waverly Hematology Oncology ( Site 0081), Cary, North Carolina

Thompson Cancer Survival Center ( Site 2812), Knoxville, Tennessee

University of Tennessee Medical Center Knoxville ( Site 0060), Knoxville, Tennessee

Renovatio Clinical ( Site 0062), The Woodlands, Texas

Cancer Care Northwest ( Site 0071), Spokane Valley, Washington

Hospital Italiano Regional del Sur ( Site 0509), Bahia Blanca, Buenos Aires

Hospital Italiano de Buenos Aires-Clinical Oncology ( Site 0511), Ciudad Autonoma de Buenos Aires, Buenos Aires

Hospital Britanico de Buenos Aires ( Site 0500), Ciudad autónoma de Buenos Aires, Buenos Aires

Instituto Medico Rio Cuarto ( Site 0501), Rio Cuarto., Cordoba

Centro Oncológico de Rosario ( Site 0507), Rosario, Santa Fe

Centro Medico San Roque ( Site 0506), San Miguel de Tucuman, Tucuman

Clínica Universitaria Reina Fabiola ( Site 0505), Cordoba, Not set

Sanatorio Privado San Geronimo S.R.L ( Site 0510), Santa Fe, Not set

Liverpool Hospital ( Site 1201), Liverpool, New South Wales

Southern Medical Day Care Centre ( Site 1200), Wollongong, New South Wales

Townsville General Hospital ( Site 1202), Townsville, Queensland

Monash Cancer Centre ( Site 1205), Clayton, Victoria

Ordensklinikum Linz GmbH Elisabethinen ( Site 1307), Linz, Oberosterreich

Klinikum Wels-Grieskirchen ( Site 1304), Wels, Oberosterreich

Innsbruck LKH ( Site 1302), Innsbruck, Tirol

Social Medical Center - Otto Wagner Hospital ( Site 1301), Vienna, Wien

Krankenhaus Nord - Klinik Floridsdorf ( Site 1300), Wien, Not set

Hospital Sao Rafael ( Site 0212), Salvador, Bahia

Instituto do Cancer do Ceara ( Site 0201), Fortaleza, Ceara

Oncologica do Brasil ( Site 0210), Belem, Para

Hospital Tacchini ( Site 0208), Bento Goncalves, Rio Grande Do Sul

Irmandade da Santa Casa de Misericordia de Porto Alegre ( Site 0209), Porto Alegre, Rio Grande Do Sul

Saint Gallen Instituto de Oncologia ( Site 0206), Santa Cruz do Sul, Rio Grande Do Sul

YNOVA Pesquisa Clinica ( Site 0215), Florianopolis, Santa Catarina

Centro de Novos Tratamentos Itajai - Clinica de Neoplasias Litoral ( Site 0202), Itajai, Santa Catarina

Centro de Hematologia e Oncologia ( Site 0205), Joinville, Santa Catarina

Hospital de Base de Sao Jose de Rio Preto ( Site 0204), Sao Jose Rio Preto, Sao Paulo

Instituto Nacional do Cancer Jose Alencar Gomes da Silva INCA ( Site 0203), Rio de Janeiro, Not set

Instituto do Cancer do Estado de Sao Paulo - ICESP ( Site 0200), Sao Paulo, Not set

BP - A Beneficencia Portuguesa de São Paulo-Medical Oncology ( Site 0214), Sao Paulo, Not set

Hospital Paulistano - Amil Clinical Research ( Site 0207), Sao Paulo, Not set

Lions Gate Hospital ( Site 0106), North Vancouver, British Columbia

BC Cancer - Victoria ( Site 0109), Victoria, British Columbia

Queen Elizabeth II Health Sciences Centre ( Site 0107), Halifax, Nova Scotia

Waterloo Regional Health Network (WRHN) ( Site 0117), Kitchener, Ontario

Stronach Regional Cancer Centre ( Site 0101), Newmarket, Ontario

Health Sciences North Research Institute ( Site 0115), Sudbury, Ontario

CISSS de la Monteregie-Centre ( Site 0114), Greenfield Park, Quebec

Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0105), Montreal, Quebec

CIUSSS Ouest de l Ile - St-Mary s Hospital ( Site 0110), Montreal, Quebec

Centre de Sante et des Services Sociaux de Rimouski-Neigette ( Site 0104), Rimouski, Quebec

CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke ( Site 0103), Sherbrooke, Quebec

Fundacion Colombiana de Cancerologia Clinica Vida ( Site 0604), Medellin, Antioquia

Clinica de la Costa S.A.S. ( Site 0608), Barranquilla, Atlantico

Administradora Country S.A. ( Site 0603), Bogota, Distrito Capital De Bogota

Clinica Colsanitas S.A. Sede Clinica Universitaria Colombia ( Site 0601), Bogotá, Distrito Capital De Bogota

Institut De Cancerologie De Lorraine ( Site 1409), Vandoeuvre les Nancy, Ain

Centre Hospitalier De Chauny ( Site 1411), Chauny, Aisne

CHU Caen ( Site 1406), Caen, Calvados

CHU Angers ( Site 1405), Angers, Maine-et-Loire

Hopital Robert Schuman ( Site 1402), Vantoux, Moselle

Centre Jean Perrin ( Site 1407), Clermont Ferrand, Puy-de-Dome

Centre Hospitalier de Pau ( Site 1412), Pau, Pyrenees-Atlantiques

CHU de Rouen ( Site 1403), Rouen, Seine-Maritime

Hopital d'Instruction des Armees Begin ( Site 1413), Saint-Mande, Val-de-Marne

Studienzentrum Aschaffenburg ( Site 1525), Aschaffenburg, Bayern

Klinikum Bogenhausen Staedt. Klinikum Muenchen GmbH ( Site 1523), Muenchen, Bayern

Klinikum der LMU ( Site 1500), Munich, Bayern

Universitaetsklinikum Regensburg ( Site 1512), Regensburg, Bayern

Klinikum Wuerzburg Mitte gGmbH ( Site 1509), Wuerzburg, Bayern

Universitaetsklinikum Frankfurt ( Site 1513), Frankfurt, Hessen

Pneumologische Lehrklinik Universitaet Goettingen ( Site 1501), Immenhausen, Hessen

Universitaetsmedizin Goettingen ( Site 1507), Goettingen, Niedersachsen

Universitaetsklinikum Bonn ( Site 1524), Bonn, Nordrhein-Westfalen

Kliniken Essen Mitte ( Site 1517), Essen, Nordrhein-Westfalen

InVo-Institut fuer Versorgungsforschung in der Onkologie ( Site 1514), Koblenz, Rheinland-Pfalz

Helios Klinikum Erfurt GmbH ( Site 1502), Erfurt, Thuringen

Katholisches Marienkrankenhaus gGmbH ( Site 1522), Hamburg, Not set

National Hospital Organization Nagoya Medical Center ( Site 0806), Nagoya, Aichi

Aichi Cancer Center ( Site 0803), Nagoya, Aichi

National Cancer Center Hospital East ( Site 0801), Kashiwa, Chiba

Kanazawa University Hospital ( Site 0811), Kanazawa, Ishikawa

Kanagawa Cancer Center ( Site 0807), Yokohama, Kanagawa

Sendai Kousei Hospital ( Site 0812), Sendai, Miyagi

Kansai Medical University Hospital ( Site 0804), Hirakata, Osaka

National Hospital Organization Kinki-chuo Chest Medical Center ( Site 0813), Sakai, Osaka

Shizuoka Cancer Center ( Site 0802), Suntogun, Shizuoka

National Hospital Organization Kyushu Medical Center ( Site 0805), Fukuoka, Not set

Niigata Cancer Center Hospital ( Site 0808), Niigata, Not set

Okayama University Hospital ( Site 0810), Okayama, Not set

Osaka International Cancer Institute ( Site 0809), Osaka, Not set

Cancer Institute Hospital of JFCR ( Site 0800), Tokyo, Not set

Chungbuk National University Hospital ( Site 1002), Cheongju si, Chungbuk

National Cancer Center ( Site 1006), Goyang-si, Kyonggi-do

The Catholic University of Korea St. Vincent s Hospital ( Site 1003), Suwon, Kyonggi-do

Ajou University Hospital ( Site 1004), Suwon, Kyonggi-do

Gyeongsang National University Hospital ( Site 1005), Jinju, Kyongsangnam-do

Asan Medical Center ( Site 1007), Songpa-gu, Seoul

Seoul National University Hospital ( Site 1000), Seoul, Not set

Korea University Guro Hospital ( Site 1008), Seoul, Not set

MidCentral DHB Palmerston North Hospital ( Site 1102), Palmerston North, Manawatu-Wanganui

Capital & Coast District Health Board - Wellington Hospital ( Site 1101), Wellington, Not set

Wielospecjalistyczny Szpital SPZOZ w Zgorzelcu ( Site 2404), Zgorzelec, Dolnoslaskie

Krakowski Szpital Specjalistyczny im Jana Pawla II ( Site 2420), Krakow, Malopolskie

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( Site 2418), Warszawa, Mazowieckie

Szpital Rejonowy im. dr Jozefa Rostka ( Site 2402), Raciborz, Slaskie

Warminsko-Mazurskie Centrum Chorob Pluc w Olsztynie ( Site 2417), Olsztyn, Warminsko-mazurskie

Przychodnia Lekarska Komed ( Site 2416), Konin, Wielkopolskie

MED-POLONIA Sp. z o.o. ( Site 2419), Poznan, Wielkopolskie

MEMORIAL HEALTHCARE INTERNATIONAL S.R.L. ( Site 2502), Bucharest, Bucuresti

Cardiomed SRL Cluj-Napoca ( Site 2504), Cluj Napoca, Cluj

S.C. Radiotherapy Center Cluj S.R.L ( Site 2507), Cluj-Napoca, Cluj

Ovidius Clinical Hospital OCH ( Site 2501), Ovidiu, Constanta

S.C. Centrul de Oncologie Sf. Nectarie SRL ( Site 2508), Craiova, Dolj

Policlinica Oncomed SRL ( Site 2505), Timisoara, Timis

Spitalul PDR Medlife ( Site 2509), Brasov, Not set

Moscow Regional Oncological Dispensary ( Site 2028), Balashikha, Moskovskaya Oblast

Russian Oncological Research Center n.a. N.N.Blokhin of MoH ( Site 2000), Moscow, Moskva

First Moscow State Medical University n.a. I.M.Sechenov ( Site 2024), Moscow, Moskva

Moscow Research Oncology Institute named after P.A. Hertsen ( Site 2009), Moscow, Moskva

FSAI Treatment and Rehabilitation Centre of the MoH and SD of RF ( Site 2006), Moscow, Moskva

Nizhniy Novgorod Region Oncology Dispensary ( Site 2026), Nizhniy Novgorod, Nizhegorodskaya Oblast

Budgetary Healthcare Institution of Omsk Region Clinical Oncology Dispensary-Chemotherapy #1 ( Site 2010), Omsk, Omskaya Oblast

SBHI Samara Regional Clinical Oncology Dispensary ( Site 2016), Samara, Samarskaya Oblast

SBHI Leningrad Regional Clinical Hospital ( Site 2002), Saint Petersburg, Sankt-Peterburg

SPb Central Clinical Railway Hospital ( Site 2003), Saint Petersburg, Sankt-Peterburg

National Medical Research Center of Oncology N.A. N.N. Petrov ( Site 2004), Saint Petersburg, Sankt-Peterburg

SPb SBHI City Clinical Oncological Dispensary ( Site 2001), Saint Petersburg, Sankt-Peterburg

Republican Clinical Oncology Dispensary of Tatarstan MoH named after professor M.Z. Sigal ( Site 2021), Kazan, Tatarstan, Respublika

Hospital Universitario Quiron Madrid ( Site 1701), Pozuelo de Alarcon, Madrid

Hospital Clinico Universitario de Valencia ( Site 1706), Valencia, Valenciana, Comunitat

Hospital del Mar ( Site 1702), Barcelona, Not set

Hospital Universitario Nuestra Senora de Valme ( Site 1703), Sevilla, Not set

Hospital Clinico Lozano Blesa ( Site 1700), Zaragoza, Not set

Chang Gung Medical Foundation. Kaohsiung Branch ( Site 0907), Kaohsiung, Not set

China Medical University Hospital ( Site 0904), Taichung, Not set

National Cheng Kung University Hospital ( Site 0905), Tainan, Not set

National Taiwan University Hospital ( Site 0900), Taipei, Not set

Mackay Memorial Hospital ( Site 0902), Taipei, Not set

Chang Gung Medical Foundation.Linkou Branch ( Site 0903), Taoyuan, Not set

Namik Kemal Universitesi Tip Fakultesi ( Site 2100), Tekirdag, Tekirdas

Baskent Unv. Adana Uyg. ve Arast. Hastanesi ( Site 2101), Adana, Not set

Gazi Universitesi Tip Fakultesi ( Site 2104), Ankara, Not set

Ankara Bilkent Sehir Hastanesi ( Site 2105), Ankara, Not set

Bezmialem Vakif Univ. Tıp Fakultesi Hastanesi Tibbi Onkoloji Bolumu ( Site 2107), Istanbul, Not set

Göztepe Prof. Dr. Süleyman Yalçın Şehir Hastanesi-oncology ( Site 2103), Istanbul, Not set

Ege Universitesi Tip Fakultesi ( Site 2109), Izmir, Not set

Erciyes Universitesi Tip Fakultesi ( Site 2108), Kayseri, Not set

Ondokuz Mayıs Universitesi-Oncology department ( Site 2106), Samsun, Not set

Cherkasy Regional Oncology Dispensary ( Site 2211), Cherkasy, Cherkaska Oblast

Municipal Non-Profit Enterprise City Clinical Hospital 4 of Dnipro City Council ( Site 2201), Dnipro, Dnipropetrovska Oblast

MI Precarpathian Clinical Oncology Center ( Site 2204), Ivano-Frankivsk, Ivano-Frankivska Oblast

Grigoriev Institute for medical Radiology NAMS of Ukraine ( Site 2212), Kharkiv, Kharkivska Oblast

CNPE "Regional Center of Oncology"-Thoracic organs ( Site 2205), Kharkiv, Kharkivska Oblast

PP PPC Acinus Medical and Diagnostic Centre ( Site 2209), Kropyvnitskiy, Kirovohradska Oblast

Medical Center Asklepion LLC ( Site 2234), Khodosivka, Kyivska Oblast

Medical Center Verum ( Site 2230), Kyiv, Kyivska Oblast

Medical and Diagnostic Centre LLC Dobryi Prognoz ( Site 2213), Kyiv, Kyivska Oblast

MI Odessa Regional Oncological Centre ( Site 2208), Odesa, Odeska Oblast

Central City Clinical Hospital ( Site 2207), Uzhgorod, Zakarpatska Oblast

Kyiv City Clinical Oncology Centre ( Site 2210), Kyiv, Not set

Barts Health NHS Trust - St Bartholomew s Hospital ( Site 1923), London, London, City Of

Chelsea and Westminster Hospital ( Site 1901), London, London, City Of

West Suffolk Hospitals NHS Trust ( Site 1919), Bury Saint Edmunds, Suffolk

Singleton Hospital ( Site 1909), Swansea, Wales

Colchester General Hospital ( Site 1911), Colchester, Worcestershire

Birmingham Heartlands Hospital ( Site 1910), Birmingham, Not set

Western General Hospital, Edinburgh ( Site 1924), Edinburg, Not set

Conditions: Carcinoma, Nonsquamous Non-small-cell Lung

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Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

NCT06236438

Recruiting

Non-Squamous Non-Small Cell Lung Cancer (NSCLC) remains a leading cause of cancer mortality worldwide, with poor survival prospects for metastatic disease. The purpose of this study is to evaluate the optimized dose, adverse events, and efficacy of livmoniplimab in combination with budigalimab plus chemotherapy versus pembrolizumab plus chemotherapy in participants with untreated metastatic non-squamous non-small cell lung cancer. Livmoniplimab is an investigational drug being developed for the treatment of NSCLC. There are 2 stages to this study. In Stage 1, there are 4 treatment arms. Participants will either receive livmoniplimab (at different doses) in combination with budigalimab (another investigational drug) + chemotherapy, budigalimab +chemotherapy, or pembrolizumab +chemotherapy. In Stage 2, there are 2 treatments arms. Participants will either receive livmoniplimab (optimized dose) in combination with budigalimab +chemotherapy or placebo in combination with pembrolizumab +chemotherapy. Chemotherapy consists of IV Infused pemetrexed + IV infused cisplatin or IV infused or injected carboplatin. Approximately 840 adult participants will be enrolled in the study across 200 sites worldwide. Stage 1: In cohort 1, participants will receive intravenously (IV) infused livmoniplimab (dose A)+ IV infused budigalimab, + chemotherapy for 4 cycles followed by livmoniplimab + budigalimab + IV Infused pemetrexed. In cohort 2, participants will receive livmoniplimab (dose B) + budigalimab + chemotherapy for 4 cycles followed by livmoniplimab + budigalimab + pemetrexed. In cohort 3, participants will receive budigalimab + chemotherapy for 4 cycles followed by budigalimab + pemetrexed . In cohort 4, participants will receive IV Infused pembrolizumab + chemotherapy for 4 cycles followed by pembrolizumab + pemetrexed. Stage 2: In arm 1, participants will receive livmoniplimab (dose optimized) + budigalimab + chemotherapy for 4 cycles followed by livmoniplimab + budigalimab + pemetrexed. In arm 2, participants will receive IV Infused placebo + pembrolizumab + chemotherapy for 4 cycles followed by pembrolizumab + pemetrexed. The estimated study duration is 55 months. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic and may require frequent medical assessments, blood tests, questionnaires, and scans. Read Less

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/29/2025

Locations: Moores Cancer Center /ID# 267782, La Jolla, California +60 locations

Moores Cancer Center /ID# 267782, La Jolla, California

Memorial Hospital West /ID# 262221, Pembroke Pines, Florida

Bond Clinic /ID# 262611, Winter Haven, Florida

University Cancer & Blood Cent /ID# 261824, Athens, Georgia

The University of Chicago Medical Center /ID# 262259, Chicago, Illinois

University of Kansas Medical Center /ID# 263196, Westwood, Kansas

Baptist Health Lexington /ID# 261823, Lexington, Kentucky

Cancer & Hematology Centers of Western Michigan - East /ID# 261826, Grand Rapids, Michigan

Washington University-School of Medicine /ID# 262759, Saint Louis, Missouri

Stony Brook Cancer Center /ID# 261954, Stony Brook, New York

Cone Health Cancer Center /ID# 262583, Greensboro, North Carolina

Oncology Hematology Care, Inc - Blue Ash /ID# 262733, Cincinnati, Ohio

Guthrie Robert Packer Hospital /ID# 262758, Sayre, Pennsylvania

Renovatio clinical /ID# 262000, El Paso, Texas

Houston Methodist Hospital /ID# 262722, Houston, Texas

Texas Oncology - Plano East /ID# 264356, Plano, Texas

Texas Oncology - San Antonio Medical Center - Research Drive /ID# 264311, San Antonio, Texas

Renovatio Clinical /ID# 261999, The Woodlands, Texas

Vista Oncology - East Olympia /ID# 262303, Olympia, Washington

Canberra Hospital /ID# 261891, Garran, Australian Capital Territory

Nepean Hospital /ID# 262157, Kingswood, New South Wales

Westmead Hospital /ID# 261894, Westmead, New South Wales

Universitair Ziekenhuis Antwerpen /ID# 261270, Edegem, Antwerpen

Cliniques Universitaires UCL Saint-Luc /ID# 261267, Bruxelles, Bruxelles-Capitale

Hospital La Louviere Site Jolimont - Helora /ID# 261269, La Louvière, Hainaut

Groupe Sante CHC - Clinique du MontLegia /ID# 262338, Liège, Liege

AZ Maria Middelares /ID# 262313, Gent, Not set

UCL Namur University Hospital, Site Sainte-Elisabeth /ID# 262557, Namur, Not set

Centro de Investigacion y Desarrollo Oncologico /ID# 261800, Temuco, Araucania

Fundacion Arturo Lopez Perez /ID# 261700, Providencia, Region Metropolitana De Santiago

Oncored /Id# 261801, Vitacura, Region Metropolitana Santiago

Sociedad Cem-Cancer Spa /Id# 262316, Viña del Mar, Valparaíso

Hospital Clinico Universidad De Los Andes /ID# 262665, Santiago, Not set

APHM - Hopital Nord /ID# 261129, Marseille, Bouches-du-Rhone

CHU Grenoble - Hopital Michallon /ID# 261131, La Tronche, Isere

Institut Curie /ID# 261127, Paris CEDEX 05, Paris

Hospices Civils de Lyon (HCL) - Hopital Louis Pradel /ID# 261644, Bron, Rhone

Centre Hosp Intercommunal de Creteil /ID# 261130, Creteil, Val-de-Marne

Shaare Zedek Medical Center /ID# 262432, Jerusalem, Yerushalayim

Rambam Health Care Campus /ID# 262431, Haifa, Not set

National Cancer Center Hospital East /ID# 261923, Kashiwa-shi, Chiba

Saitama Cancer Center /ID# 262703, Kitaadachi-gun, Saitama

National Cancer Center Hospital /ID# 261925, Chuo-ku, Tokyo

Ziekenhuis St. Jansdal /ID# 261193, Harderwijk, Gelderland

Zuyderland Medisch Centrum /ID# 261190, Heerlen, Limburg

Isala /ID# 262458, Zwolle, Overijssel

Pan American Center for Oncology Trials /ID# 269666, Rio Piedras, Not set

Complejo Hospitalario Universitario de Santiago (CHUS) /ID# 262723, Santiago de Compostela, A Coruna

Institut Català d'Oncologia (ICO) - L'Hospitalet /ID# 262118, L'Hospitalet de Llobregat, Barcelona

UOMi Cancer Center - Clinica Tres Torres /ID# 262116, Barcelona, Not set

Hospital Universitario Vall d'Hebron /ID# 262113, Barcelona, Not set

Hospital General Universitario Gregorio Maranon /ID# 262114, Madrid, Not set

Hospital Universitario 12 de Octubre /ID# 262112, Madrid, Not set

Hospital Clinico Universitario de Valencia /ID# 262115, Valencia, Not set

National Cheng Kung University Hospital /ID# 262016, Tainan, Not set

Mackay Memorial Hospital /ID# 262534, Taipei City, Not set

Taipei Medical University Hospital /ID# 262020, Taipei City, Not set

Linkou Chang Gung Memorial Hospital /ID# 262535, Taoyuan City, Not set

Gazi University Medical Faculty /ID# 261786, Ankara, Not set

Ankara City Hospital /ID# 261785, Ankara, Not set

Dr. Suat Seren Gogus Has /ID# 261789, Izmir, Not set

Conditions: Non-Small Cell Lung Cancer

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Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Patients With Stage I-III Adrenocortical Cancer With High Risk of Recurrence

NCT03583710

Recruiting

This phase III trial studies how well mitotane alone works compared to mitotane with cisplatin and etoposide when given after surgery in treating patients with adrenocortical cancer that has a high risk of coming back (recurrence). Cortisol can cause the growth of adrenocortical tumor cells. Antihormone therapy, such as mitotane, may lessen the amount of cortisol made by the body. Drugs used in chemotherapy, such as cisplatin and etoposide, work in different ways to stop the growth of tumor cell... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/29/2025

Locations: University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan +7 locations

Conditions: ENSAT Stage I Adrenal Cortex Carcinoma, ENSAT Stage II Adrenal Cortex Carcinoma, ENSAT Stage III Adrenal Cortex Carcinoma

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PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

NCT04329494

Recruiting

This phase I trial studies the side effects of pressurized intraperitoneal aerosol chemotherapy (PIPAC) in treating patients with ovarian, uterine, appendiceal, stomach (gastric), or colorectal cancer that has spread to the lining of the abdominal cavity (peritoneal carcinomatosis). Chemotherapy drugs, such as cisplatin, doxorubicin, oxaliplatin, leucovorin, fluorouracil, mitomycin, and irinotecan, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/28/2025

Locations: City of Hope Medical Center, Duarte, California +2 locations

Conditions: Clinical Stage IV Gastric Cancer AJCC v8, Clinical Stage IVA Gastric Cancer AJCC v8, Clinical Stage IVB Gastric Cancer AJCC v8, Malignant Uterine Neoplasm, Metastatic Colorectal Carcinoma, Metastatic Gastric Carcinoma, Metastatic Malignant Neoplasm in the Peritoneum, Metastatic Ovarian Carcinoma, Pathologic Stage IV Gastric Cancer AJCC v8, Peritoneal Carcinomatosis, Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8, Stage IV Colorectal Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Uterine Corpus Cancer AJCC v8, Stage IVA Colorectal Cancer AJCC v8, Stage IVA Ovarian Cancer AJCC v8, Stage IVA Uterine Corpus Cancer AJCC v8, Stage IVB Colorectal Cancer AJCC v8, Stage IVB Ovarian Cancer AJCC v8, Stage IVB Uterine Corpus Cancer AJCC v8, Stage IVC Colorectal Cancer AJCC v8, Metastatic Appendix Carcinoma, Metastatic Malignant Solid Neoplasm, Stage IV Appendix Carcinoma AJCC v8, Stage IVA Appendix Carcinoma AJCC v8, Stage IVB Appendix Carcinoma AJCC v8, Stage IVC Appendix Carcinoma AJCC v8

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Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

NCT04900623

Recruiting

This research is being conducted to understand if treatment can be tailored for participants with HPV-related oropharynx cancers using both clinical features (stage of the tumor, smoking status) combined with an investigational HPV blood test. The names of the test and treatments involved in this study are: * NavDx® HPV ctDNA testing (HPV blood test) * Radiation therapy * Chemotherapy: Cisplatin, or Carboplatin and Paclitaxel (not all participants receive any or all of these agents)

Gender:

ALL

Ages:

22 years and above

Trial Updated:

07/28/2025

Locations: Brigham and Women's Hospital, Boston, Massachusetts +1 locations

Conditions: HPV-Associated Oropharyngeal Squamous Cell Carcinoma, HPV Positive Oropharyngeal Squamous Cell Carcinoma, HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Stage, HPV-Related Squamous Cell Carcinoma, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Clinical Stage, HPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Pathologic Stage

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A Study of Tislelizumab (BGB-A317) in Combination With Chemotherapy as First Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma

NCT03783442

Completed

The purpose of this study is to evaluate the efficacy and safety of tislelizumab as first line treatment in combination with chemotherapy in participants with advanced unresectable/metastatic esophageal squamous cell carcinoma (ESCC).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/28/2025

Locations: Smilow Cancer Hospital At Yale, New Haven, Connecticut +123 locations

Smilow Cancer Hospital At Yale, New Haven, Connecticut

Renovatio Clinical, The Woodlands, Texas

Coffs Harbour Base Hospital, Coffs Harbour, New South Wales

St Vincents Hospital Melbourne, Fitzroy, Victoria

Institut Jules Bordet, Anderlecht, Not set

Az Sint Jan Brugge, Brugge, Not set

Grand Hopital de Charleroi Site Notre Dame, Charleroi, Not set

UZ GENT, Gand, Not set

University Hospitals Leuven, Leuven, Not set

Chc Montlegia, Liege, Not set

Anhui Provincial Hospital, Hefei, Anhui

Anhui Provincial Cancer Hospital Aka West Branch of Anhui Province Hospital, Hefei, Anhui

The Second Hospital of Anhui Medical University, Hefei, Anhui

Beijing Friendship Hospital, Capital Medical University, Beijing, Beijing

The Fifth Medical Center of Chinese Pla General Hospital, Beijing, Beijing

Beijing Cancer Hospital, Beijing, Beijing

Peking Union Medical College Hospital, Beijing, Beijing

The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian

Fujian Cancer Hospital, Fuzhou, Fujian

Quanzhou First Affliated Hospital of Fujian Medical University, Quanzhou, Fujian

The First Affiliated Hospital of Xiamen University, Xiamen, Fujian

Zhongshan Hospital Xiamen University, Xiamen, Fujian

The First Affiliated Hospital, Sun Yat Sen University, Guangzhou, Guangdong

The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, Guangdong

Guangdong Province Traditional Chinese Medical Hospitsal, Guangzhou, Guangdong

The Sixth Affiliated Hospital, Sun Yat Sen University, Guangzhou, Guangdong

Cancer Hospital of Shantou University Medical College, Shantou, Guangdong

The Tumor Hospital Affiliated to Guangxi Medical University, Nanning, Guangxi

Hainan General Hospital, Haikou, Hainan

Harbin Medical University Cancer Hospital, Harbin, Heilongjiang

The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan

Henan Cancer Hospital, Zhengzhou, Henan

The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan

Hubei Cancer Hospital, Wuhan, Hubei

Xiangyang Central Hospital, Xiangyang, Hubei

Hunan Cancer Hospital, Changsha, Hunan

The First Peoples Hospital of Changzhou, Changzhou, Jiangsu

Jiangsu Province Hospital, Nanjing, Jiangsu

Nantong Tumor Hospital Branch North, Nantong, Jiangsu

Affiliated Hospital of Jiangnan University North Campus (Wuxi Fourth Peoples Hospital ), Wuxi, Jiangsu

The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu

The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi

Liaoning Cancer Hospital and Institute, Shenyang, Liaoning

Shandong Cancer Hospital, Jinan, Shandong

Linyi Cancer Hospital, Linyi, Shandong

Weifang Peoples Hospital, Weifang, Shandong

Fudan University Shanghai Cancer Center, Shanghai, Shanghai

Shanxi Provincial Peoples Hospital, Taiyuan, Shanxi

Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang

Zhejiang Cancer Hospital, Hangzhou, Zhejiang

Fakultni Thomayerova Nemocnice, Praha, Not set

Chru de Brest Hopital Cavale Blanche, Brest, Not set

Chu Besancon Hopital Jean Minjoz, Doubs, Not set

Hopital Franco Britannique, LevalloisPerret, Not set

Centre Oscar Lambret, Lille, Not set

Centre Leon Berard, Lyon Cedex, Not set

Hopital Saint Antoine Service Dhepato Gastro Enterologie, Paris Cedex, Not set

Hopital Europeen Georges Pompidou, Paris, Not set

Chu Bordeaux Hopital Haut Leveque, Pessac, Not set

Chu de Poitiers Site de La Mileterie, Poitiers, Not set

Centre de Lutte Contre Le Cancer Institut de Cancerologie de Louest Rene Gauducheau, SaintHerblain, Not set

Universitatsklinikum Hamburg Eppendorf, Hamburg, Not set

Slk Kliniken Heilbronn Gmbh Klinik Fur Radiologie, Minimalinvasive Therapien Und Nuklearmedizin, Heilbronn, Not set

Universitares Krebszentrum Leipzig, Leipzig, Not set

Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori Irst, Meldola, Not set

Istituto Europeo Di Oncologia, Milano, Not set

Istituto Nazionale Tumori Fondazione G Pascale, Napoli, Not set

Iov Istituto Oncologico Veneto Irccs, Padova, Not set

Azienda Ospedaliera Universitaria Delle Marche, Torrette, Not set

Akita University Hospital, Akitashi, Akita

National Cancer Center Hospital East, Kashiwa, Chiba

National Hospital Organization Kyushu Medical Center, Fukuokacity, Fukuoka

Nho Kyushu Cancer Center, FukuokaShi, Fukuoka

Hyogo Cancer Center, AkashiShi, Hyogo

Johas Kansai Rosai Hospital, Amagasakishi, Hyogo

Kanagawa Cancer Center, Yokohamashi, Kanagawa

University Hospital, Kyoto Prefectural Univ of Medicine, KyotoShi, Kyoto

Osaka International Cancer Institute, OsakaShi, Osaka

The University of Osaka Hospital, Suitashi, Osaka

Saitama Cancer Center, Kitaadachigun, Saitama

National Cancer Center Hospital, ChuoKu, Tokyo

Hiroshima University Hospital, Hiroshima, Not set

Kumamoto University Hospital, Kumamoto, Not set

Niigata Cancer Center Hospital, Niigata, Not set

Keimyung University Dongsan Hospital, Dalseogu, Daegu Gwang'yeogsi

Cha Bundang Medical Center, Cha University, BundangGu SeongnamSi, Gyeonggi-do

Seoul National University Bundang Hospital, BundangGu SeongnamSi, Gyeonggi-do

Gachon University Gil Medical Center, NamdongGu, Incheon Gwang'yeogsi

Chonnam National University Hwasun Hospital, HwasunGun, Jeollanam-do

Smg Snu Boramae Medical Center, DongjakGu, Seoul Teugbyeolsi

Korea University Guro Hospital, GuroGu, Seoul Teugbyeolsi

The Catholic University of Korea, Seoul St Marys Hospital, SeochoGu, Seoul Teugbyeolsi

Samsung Medical Center Hematology Oncology, Seoul, Seoul Teugbyeolsi

Asan Medical Center, SongpaGu, Seoul Teugbyeolsi

Szpital Specjalist W Brzozowie,Podkarpacki Osrodek Onkologiczny, Brzozow, Not set

Szpital Wojewodzki Im Mikoaja Kopernika W Koszalinie, Koszalin, Not set

Spzoz Mswia Z Warminsko Mazurskim Centrum Onkologii, Olsztyn, Not set

Narodowy Instytut Onkologii Im Marii Skodowskiej Curie Pastwowy Instytut Badawczy, Warszawa, Not set

Institutul Oncologic Prof Dr Ion Chiricuta Cluj Napoca, ClujNapoca, Not set

Medisprof Cancer Center, ClujNapoca, Not set

Radiotherapy Center Cluj, ClujNapoca, Not set

Sc Centrul de Oncologie Sf Nectarie Srl, Craiova, Not set

Arkhangelsk Regional Clinical Oncological Dispensary, Arkhangelsk, Arkhangel'skaya Oblast'

Rbih Ivanovo Regional Oncological Dispensary, Ivanovo, Ivanovskaya Oblast'

State Budget Healthcare Institution Leningrad Regional Clinical Oncologic Dispensary, Kuzmolovsky, Leningradskaya Oblast'

Orenburg Regional Clinical Oncology Center, Orenburg, Orenburgskaya Oblast'

Rostov State Medical University, RostovonDon, Rostovskaya Oblast'

Pavlov First Saint Petersburg State Medical University, SaintPetersburg, Sankt-Peterburg

Fsbi National Medical Research Center For Oncology Na Nn Petrov of the Moh of the Rf, SaintPetersburg, Not set

Hospital Universitario Vall Dhebron, Barcelona, Not set

Institut Catala Doncologia, Barcelona, Not set

Hospital Clinic de Barcelona, Barcelona, Not set

Hospital General Universitario Gregorio Maranon, Madrid, Not set

Hospital Regional Universitario de Malaga, Malaga, Not set

Hospital Universitario Central de Asturias, Oviedo, Not set

Hospital Universitario Miguel Servet, Zaragoza, Not set

Chiayi Chang Gung Memorial Hospital, Chiayi, Not set

Chi Mei Hospital Liouying, Liuying Dist, Not set

China Medical University Hospital, North Dist, Not set

Chi Mei Medical Center, Yongkang Dist, Not set

The Christie Hospital, Greater Manchester, Not set

Guys and St Thomas Hospital Nhs Foundation Trust, London, Not set

Conditions: Esophageal Squamous Cell Carcinoma (ESCC)

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Gemcitabine, Cisplatin and Nab-Paclitaxel as Neoadjuvant Treatment for Patients With Resectable or Borderline Resectable Pancreatic Cancer

NCT06423326

Recruiting

This phase II trial tests how well gemcitabine, cisplatin and nab-paclitaxel given before surgery (neoadjuvant) works in treating patients with pancreatic cancer that can be removed by surgery (resectable) or that is borderline resectable. The standard treatment for resectable and borderline resectable pancreatic cancer is a combination of surgery and chemotherapy. Neoadjuvant therapy has been shown to improve overall survival compared to patients receiving surgery first. Gemcitabine is a chemot... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/25/2025

Locations: Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia

Conditions: Borderline Resectable Pancreatic Ductal Adenocarcinoma, Resectable Pancreatic Adenocarcinoma, Stage I Pancreatic Cancer AJCC v8, Stage II Pancreatic Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8

Learn More ›

A Study of Cemiplimab With Chemotherapy and Immunotherapy in People With Head and Neck Cancer

NCT04722523

Recruiting

The purpose of this study is to find out whether combining the standard chemotherapy for head and neck cancer with the immunotherapy drugs cetuximab and cemiplimab (the study drug) is a safe treatment for head and neck cancer, and whether receiving this combination treatment before surgery may allow participants to forgo the standard radiation treatment after surgery.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/25/2025

Locations: Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey +6 locations

Conditions: Head and Neck Cancer, Head Cancer, Head Cancer Neck, Neck Cancer, Head and Neck Squamous Cell Carcinoma, HNSCC

Learn More ›

Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer

NCT05819892

Recruiting

To learn if chemotherapy given in combination with radiation therapy, followed by maintenance therapy, can help to control endometrial cancer. The safety and effects of this study treatment will also be studied

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

07/25/2025

Locations: M D Anderson Cancer Center, Houston, Texas

Conditions: Endometrial Cancer

Learn More ›

A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, INSPIRE Trial

NCT04216290

Active Not Recruiting

This phase II trial studies the benefit of adding an immunotherapy drug called MEDI4736 (durvalumab) to standard chemotherapy and radiation therapy in treating bladder cancer which has spread to the lymph nodes. Drugs used in standard chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Cisplatin is in a class of medications known as platinum-containing compounds. It works by killin... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/25/2025

Locations: Anchorage Associates in Radiation Medicine, Anchorage, Alaska +215 locations

Anchorage Associates in Radiation Medicine, Anchorage, Alaska

Alaska Breast Care and Surgery LLC, Anchorage, Alaska

Alaska Oncology and Hematology LLC, Anchorage, Alaska

Alaska Women's Cancer Care, Anchorage, Alaska

Anchorage Oncology Centre, Anchorage, Alaska

Katmai Oncology Group, Anchorage, Alaska

Providence Alaska Medical Center, Anchorage, Alaska

Mercy Hospital Fort Smith, Fort Smith, Arkansas

CHI Saint Vincent Cancer Center Hot Springs, Hot Springs, Arkansas

Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California

VA Palo Alto Health Care System, Palo Alto, California

Penrose-Saint Francis Healthcare, Colorado Springs, Colorado

Rocky Mountain Cancer Centers-Penrose, Colorado Springs, Colorado

AdventHealth Porter, Denver, Colorado

Saint Anthony Hospital, Lakewood, Colorado

AdventHealth Littleton, Littleton, Colorado

Longmont United Hospital, Longmont, Colorado

AdventHealth Parker, Parker, Colorado

Saint Mary Corwin Medical Center, Pueblo, Colorado

Beebe South Coastal Health Campus, Millville, Delaware

Helen F Graham Cancer Center, Newark, Delaware

Medical Oncology Hematology Consultants PA, Newark, Delaware

Beebe Health Campus, Rehoboth Beach, Delaware

Sibley Memorial Hospital, Washington, District of Columbia

Holy Cross Hospital, Fort Lauderdale, Florida

Mount Sinai Medical Center, Miami Beach, Florida

Emory University Hospital Midtown, Atlanta, Georgia

Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho

Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho

Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho

Idaho Urologic Institute-Meridian, Meridian, Idaho

Saint Luke's Cancer Institute - Meridian, Meridian, Idaho

Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho

Saint Luke's Cancer Institute - Nampa, Nampa, Idaho

Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho

Saint Luke's Cancer Institute - Twin Falls, Twin Falls, Idaho

Rush-Copley Medical Center, Aurora, Illinois

Illinois CancerCare-Bloomington, Bloomington, Illinois

Illinois CancerCare-Canton, Canton, Illinois

Memorial Hospital of Carbondale, Carbondale, Illinois

SIH Cancer Institute, Carterville, Illinois

Illinois CancerCare-Carthage, Carthage, Illinois

Centralia Oncology Clinic, Centralia, Illinois

Northwestern University, Chicago, Illinois

Carle at The Riverfront, Danville, Illinois

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois

Decatur Memorial Hospital, Decatur, Illinois

Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Crossroads Cancer Center, Effingham, Illinois

Illinois CancerCare-Eureka, Eureka, Illinois

Illinois CancerCare-Galesburg, Galesburg, Illinois

Western Illinois Cancer Treatment Center, Galesburg, Illinois

Northwestern Medicine Cancer Center Delnor, Geneva, Illinois

Edward Hines Jr VA Hospital, Hines, Illinois

Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois

Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois

Illinois CancerCare-Macomb, Macomb, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

Loyola University Medical Center, Maywood, Illinois

SSM Health Good Samaritan, Mount Vernon, Illinois

Cancer Care Center of O'Fallon, O'Fallon, Illinois

Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois

Illinois CancerCare-Pekin, Pekin, Illinois

OSF Saint Francis Radiation Oncology at Pekin, Pekin, Illinois

Illinois CancerCare-Peoria, Peoria, Illinois

OSF Saint Francis Radiation Oncology at Peoria Cancer Center, Peoria, Illinois

Methodist Medical Center of Illinois, Peoria, Illinois

OSF Saint Francis Medical Center, Peoria, Illinois

Illinois CancerCare-Peru, Peru, Illinois

Valley Radiation Oncology, Peru, Illinois

Illinois CancerCare-Princeton, Princeton, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Springfield Clinic, Springfield, Illinois

Springfield Memorial Hospital, Springfield, Illinois

Carle Cancer Center, Urbana, Illinois

The Carle Foundation Hospital, Urbana, Illinois

Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois

Mary Greeley Medical Center, Ames, Iowa

McFarland Clinic - Ames, Ames, Iowa

Mercy Cancer Center-West Lakes, Clive, Iowa

UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive, Iowa

Greater Regional Medical Center, Creston, Iowa

Iowa Methodist Medical Center, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Des Moines Clinic, Des Moines, Iowa

Broadlawns Medical Center, Des Moines, Iowa

Mercy Medical Center - Des Moines, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines, Iowa

Iowa Lutheran Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

Methodist West Hospital, West Des Moines, Iowa

Mercy Medical Center-West Lakes, West Des Moines, Iowa

Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky

Saint Joseph Hospital East, Lexington, Kentucky

Jewish Hospital, Louisville, Kentucky

Baptist Health Louisville, Louisville, Kentucky

UofL Health Medical Center Northeast, Louisville, Kentucky

East Jefferson General Hospital, Metairie, Louisiana

LSU Healthcare Network / Metairie Multi-Specialty Clinic, Metairie, Louisiana

Louisiana State University Health Science Center, New Orleans, Louisiana

University Medical Center New Orleans, New Orleans, Louisiana

Eastern Maine Medical Center, Bangor, Maine

Lafayette Family Cancer Center-EMMC, Brewer, Maine

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan

Trinity Health Medical Center - Brighton, Brighton, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan

Trinity Health Medical Center - Canton, Canton, Michigan

Chelsea Hospital, Chelsea, Michigan

Henry Ford Health Saint John Hospital, Detroit, Michigan

Genesys Hurley Cancer Institute, Flint, Michigan

Hurley Medical Center, Flint, Michigan

University of Michigan Health - Sparrow Lansing, Lansing, Michigan

Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan

Michigan Healthcare Professionals Pontiac, Pontiac, Michigan

Trinity Health Saint Joseph Mercy Oakland Hospital, Pontiac, Michigan

MyMichigan Medical Center Saginaw, Saginaw, Michigan

Henry Ford Health Warren Hospital, Warren, Michigan

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan

Essentia Health Saint Joseph's Medical Center, Brainerd, Minnesota

Mercy Hospital, Coon Rapids, Minnesota

Essentia Health - Deer River Clinic, Deer River, Minnesota

Essentia Health Cancer Center, Duluth, Minnesota

Essentia Health Saint Mary's Medical Center, Duluth, Minnesota

Miller-Dwan Hospital, Duluth, Minnesota

Unity Hospital, Fridley, Minnesota

Essentia Health Hibbing Clinic, Hibbing, Minnesota

Essentia Health Sandstone, Sandstone, Minnesota

Essentia Health Virginia Clinic, Virginia, Minnesota

Mercy Oncology and Hematology - Clayton-Clarkson, Ballwin, Missouri

Mercy Cancer Center - Cape Girardeau, Cape Girardeau, Missouri

Saint Francis Medical Center, Cape Girardeau, Missouri

Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri

Parkland Health Center - Farmington, Farmington, Missouri

MU Health Care Goldschmidt Cancer Center, Jefferson City, Missouri

Mercy Hospital Joplin, Joplin, Missouri

Mercy Clinic-Rolla-Cancer and Hematology, Rolla, Missouri

Phelps Health Delbert Day Cancer Institute, Rolla, Missouri

Heartland Regional Medical Center, Saint Joseph, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital South, Saint Louis, Missouri

Siteman Cancer Center-South County, Saint Louis, Missouri

Missouri Baptist Medical Center, Saint Louis, Missouri

Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri

Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri

Mercy Hospital Springfield, Springfield, Missouri

CoxHealth South Hospital, Springfield, Missouri

Missouri Baptist Sullivan Hospital, Sullivan, Missouri

BJC Outpatient Center at Sunset Hills, Sunset Hills, Missouri

Billings Clinic Cancer Center, Billings, Montana

Bozeman Health Deaconess Hospital, Bozeman, Montana

Benefis Sletten Cancer Institute, Great Falls, Montana

Great Falls Clinic, Great Falls, Montana

Logan Health Medical Center, Kalispell, Montana

Community Medical Center, Missoula, Montana

Nebraska Cancer Specialists/Oncology Hematology West PC, Grand Island, Nebraska

CHI Health Good Samaritan, Kearney, Nebraska

Alegent Health Immanuel Medical Center, Omaha, Nebraska

Alegent Health Bergan Mercy Medical Center, Omaha, Nebraska

Alegent Health Lakeside Hospital, Omaha, Nebraska

Creighton University Medical Center, Omaha, Nebraska

University of New Mexico Cancer Center, Albuquerque, New Mexico

Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio

Bethesda North Hospital, Cincinnati, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Mercy Hospital Oklahoma City, Oklahoma City, Oklahoma

Saint Charles Health System, Bend, Oregon

Clackamas Radiation Oncology Center, Clackamas, Oregon

Providence Cancer Institute Clackamas Clinic, Clackamas, Oregon

Bay Area Hospital, Coos Bay, Oregon

Providence Newberg Medical Center, Newberg, Oregon

Providence Portland Medical Center, Portland, Oregon

Providence Saint Vincent Medical Center, Portland, Oregon

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania

Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania

Pocono Medical Center, East Stroudsburg, Pennsylvania

Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania

Gibbs Cancer Center-Gaffney, Gaffney, South Carolina

Gibbs Cancer Center-Pelham, Greer, South Carolina

Spartanburg Medical Center, Spartanburg, South Carolina

SMC Center for Hematology Oncology Union, Union, South Carolina

University of Tennessee - Knoxville, Knoxville, Tennessee

Saint Joseph Regional Cancer Center, Bryan, Texas

Sovah Health Martinsville, Martinsville, Virginia

Providence Regional Cancer System-Aberdeen, Aberdeen, Washington

PeaceHealth Saint Joseph Medical Center, Bellingham, Washington

Highline Medical Center-Main Campus, Burien, Washington

Providence Regional Cancer System-Centralia, Centralia, Washington

Swedish Cancer Institute-Edmonds, Edmonds, Washington

Providence Regional Cancer Partnership, Everett, Washington

Swedish Cancer Institute-Issaquah, Issaquah, Washington

Providence Regional Cancer System-Lacey, Lacey, Washington

PeaceHealth Saint John Medical Center, Longview, Washington

Swedish Medical Center-Ballard Campus, Seattle, Washington

Swedish Medical Center-First Hill, Seattle, Washington

PeaceHealth United General Medical Center, Sedro-Woolley, Washington

Saint Michael Cancer Center, Silverdale, Washington

PeaceHealth Southwest Medical Center, Vancouver, Washington

Providence Saint Mary Regional Cancer Center, Walla Walla, Washington

Duluth Clinic Ashland, Ashland, Wisconsin

Northwest Wisconsin Cancer Center, Ashland, Wisconsin

Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Marshfield Medical Center - Minocqua, Minocqua, Wisconsin

Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin

Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin

Marshfield Medical Center - Weston, Weston, Wisconsin

Welch Cancer Center, Sheridan, Wyoming

Conditions: Bladder Urothelial Carcinoma, Stage III Bladder Cancer AJCC v8

Learn More ›

Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer

NCT02595879

Active Not Recruiting

This phase I trial studies the side effects and best dose of triapine when given with radiation therapy and cisplatin in treating patients with stage IB2-IVA cervical or vaginal cancer. Triapine may stop the growth of cancer cells by blocking an enzyme needed for cell growth. Cisplatin is a drug used in chemotherapy that kills cancer cells by damaging their deoxyribonucleic acid (DNA) and stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells and shrink tumors... Read More

Gender:

FEMALE

Ages:

18 years and above

Trial Updated:

07/25/2025

Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama +16 locations

Conditions: Stage IB2 Cervical Cancer AJCC v6 and v7, Stage II Cervical Cancer AJCC v7, Stage II Vaginal Cancer AJCC v6 and v7, Stage III Vaginal Cancer AJCC v6 and v7, Stage IIIB Cervical Cancer AJCC v6 and v7, Stage IVA Cervical Cancer AJCC v6 and v7, Stage IVA Vaginal Cancer AJCC v6 and v7, Advanced Cervical Adenocarcinoma, Advanced Cervical Adenosquamous Carcinoma, Advanced Cervical Squamous Cell Carcinoma, Advanced Vaginal Adenocarcinoma, Advanced Vaginal Adenosquamous Carcinoma, Advanced Vaginal Squamous Cell Carcinoma

Learn More ›

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