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                    Cisplatin Treatment Options
A collection of 1441 research studies where Cisplatin is the interventional treatment. These studies are located in the  United States . Cisplatin is used for conditions such as Head and Neck Cancer, Lung Cancer and Non-Small Cell Lung Cancer.
            193 - 204 of 1441
        Featured Trial
                
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                            Conditions: 
                                    
        
            
                        Healthy
                    
                                    
                        Healthy Volunteers
                    
                                    
                        Healthy Subjects
                    
                                    
                        Healthy Volunteer
                    
                                    
                        Healthy Participants
                    
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        Recruiting
            
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                            Conditions: 
                                    
        
            
                        Overweight
                    
                                    
                        Overweight and Obesity
                    
                                    
                        Obesity
                    
                                    
                        Weight Loss
                    
                                    
                        Morbid Obesity
                    
                                    Featured Trial
                
                Stroke Clinical Study
            
        Recruiting
            
        A clinical study for people that suffer with Stroke
    
    
                            Conditions: 
                                    
        
            
                        Stroke
                    
                                    Featured Trial
                
                Chronic Kidney Disease (CKD) Clinical Study
            
        Recruiting
            
        A clinical study for people that suffer with Chronic Kidney Disease (CKD)
    
    
                            Conditions: 
                                    
        
            
                        Chronic Kidney Disease (CKD)
                    
                                    
                
                                    A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss
                                
            
            
        Recruiting
                            
            
                This phase III trial tests two hypotheses in patients with low-risk and average-risk medulloblastoma. Medulloblastoma is a type of cancer that occurs in the back of the brain. The term, risk, refers to the chance of the cancer coming back after treatment. Subjects with low-risk medulloblastoma typically have a lower chance of the cancer coming back than subjects with average-risk medulloblastoma. Although treatment for newly diagnosed average-risk and low-risk medulloblastoma is generally effect...  Read More             
        
        
    Gender:
                ALL
            Ages:
                Between 4 years and 21 years
            Trial Updated:
                07/10/2025
            
            Locations: Children's Hospital of Alabama, Birmingham, Alabama  +80 locations         
        
        
            Conditions: Childhood Medulloblastoma
        
            
        
    
                
                                    Study of Dato-Dxd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
                                
            
            
        Recruiting
                            
            
                TROPION-PanTumor03 will investigate the safety, tolerability, and anti-tumour activity of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Combination with Anticancer Agents in Patients with Advanced/Metastatic Solid Tumours.             
        
        
    Gender:
                ALL
            Ages:
                Between 18 years and 130 years
            Trial Updated:
                07/10/2025
            
            Locations: Research Site, Los Angeles, California  +94 locations         
        
        
            Conditions: Endometrial Cancer, Gastric Cancer, Metastatic Castration-resistant Prostate Cancer, Ovarian Cancer, Colorectal Cancer, Urothelial Cancer, Biliary Tract Cancer
        
            
        
    
                
                                    A Study to Evaluate Chemotherapy Plus Osimertinib Against Chemotherapy Plus Placebo in Patients With Non-small Cell Lung Cancer (NSCLC)
                                
            
            
        Active Not Recruiting
                            
            
                The study will evaluate the efficacy and safety of treatment with chemotherapy in combination with osimertinib compared to chemotherapy in combination with placebo in patients whose disease has progressed extracranially following first-line osimertinib treatment.             
        
        
    Gender:
                ALL
            Ages:
                Between 18 years and 130 years
            Trial Updated:
                07/09/2025
            
            Locations: Research Site, Silver Spring, Maryland  +39 locations         
        
        
            Conditions: Non-small Cell Lung Cancer
        
            
        
    
                
                                    A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
                                
            
            
        Recruiting
                            
            
                This is a Phase Ⅲ, randomized, open-label, Sponsor-blinded, 3-arm, global, multicenter study assessing the efficacy and safety of rilvegostomig in combination with fluoropyrimidine and T-DXd (Arm A) compared to trastuzumab, chemotherapy, and pembrolizumab (Arm B) in HER2-positive locally advanced or metastatic gastric or GEJ adenocarcinoma participants whose tumors express PD L1 CPS ≥ 1. Rilvegostomig in combination with trastuzumab and chemotherapy will be evaluated in a separate arm (Arm C) to...  Read More             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                07/09/2025
            
            Locations: Research Site, Anchorage, Alaska  +264 locations         
        
        
            Conditions: HER2-positive Gastric Cancer, Gastroesophageal Junction Adenocarcinoma
        
            
        
    
                
                                    A Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Standard of Care, Following Complete Tumour Resection, in Participants With Stage I Adenocarcinoma NSCLC Who Are ctDNA-positive or Have High-risk Pathological Features
                                
            
            
        Recruiting
                            
            
                This is a Phase III, randomised, open-label, multicentre, global study assessing the efficacy and safety of adjuvant Dato-DXd in combination with rilvegostomig compared with SoC, after complete surgical resection (R0) in participants with Stage I adenocarcinoma NSCLC who are ctDNA-positive, as determined by the Sponsor-designated ctDNA assay, or have at least one high-risk pathological feature.             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                07/09/2025
            
            Locations: Research Site, Gilbert, Arizona  +220 locations         
        
        
            Conditions: Non-small Cell Lung Cancer
        
            
        
    
                
                                    A Study of Subcutaneous (SC) Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77)
                                
            
            
        Active Not Recruiting
                            
            
                This study is to assess the pharmacokinetics (PK) and safety of SC pembrolizumab formulated with berahyaluronidase alfa (MK-3475A) versus (vs) intravenous (IV) pembrolizumab (MK-3475), administered with chemotherapy in first line treatment of adult participants with metastatic non-small cell lung cancer. The primary hypotheses of this study are pembrolizumab formulated with berahyaluronidase alfa subcutaneous (SC) is noninferior to pembrolizumab IV with respect to PK parameters.             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                07/08/2025
            
            Locations: St. Joseph's Hospital and Medical Center-Dignity Health Cancer Institute ( Site 0023), Phoenix, Arizona  +109 locations         
        
        
            Conditions: Metastatic Non-small Cell Lung Cancer
        
            
        
    
                
                                    Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-859/KEYNOTE-859)
                                
            
            
        Completed
                            
            
                The purpose of this study is to evaluate the efficacy of pembrolizumab (MK-3745) in combination with chemotherapy (Cisplatin combined with 5-Fluorouracil \[FP regimen\] or oxaliplatin combined with capecitabine \[CAPOX regimen\]) versus placebo in combination with chemotherapy (FP or CAPOX regimens) in the treatment of human epidermal growth factor receptor 2 (HER2) negative advanced gastric or GEJ adenocarcinoma in adult participants.
The primary hypotheses of this study are that pembrolizumab...  Read More             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                07/08/2025
            
            Locations: UCLA Hematology/Oncology - Westwood (Building 200 Suite 120) ( Site 0124), Los Angeles, California  +214 locations         
        
        
            Conditions: Stomach Neoplasms
        
            
        
    
                
                                    A Study to Investigate the Efficacy and Safety of Trastuzumab Deruxtecan as the First Treatment Option for Unresectable, Locally Advanced/Metastatic Non-Small Cell Lung Cancer With HER2 Mutations
                                
            
            
        Recruiting
                            
            
                DESTINY-Lung04 will investigate the efficacy and safety of Trastuzumab Deruxtecan (T-DXd) versus Standard of Care (SoC) as first-line treatment of Non-Small Cell Lung Cancer (NSCLC) with HER2 Exon 19 or 20 mutations             
        
        
    Gender:
                ALL
            Ages:
                Between 18 years and 123 years
            Trial Updated:
                07/07/2025
            
            Locations: Research Site, Anchorage, Alaska  +162 locations         
        
        
            Conditions: Locally Advanced or Metastatic Non-Small Cell Lung Cancer
        
            
        
    
                
                                    Study Evaluating a Stereotactic Boost/Treatment for Recurrent or Metastatic Cancer of the Head and Neck
                                
            
            
        Active Not Recruiting
                            
            
                This research study seeks to gain new knowledge about the addition of a carefully targeted "boost" dose of radiation as a possible treatment for recurrent or metastatic head or neck cancer. The name of the study intervention involved in this study is stereotactic body radiotherapy, which is a way of delivering radiation in a more precisely targeted way and with a higher dose than conventional radiotherapy.             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                07/07/2025
            
            Locations: Dana-Farber Cancer Institute, Boston, Massachusetts         
        
        
            Conditions: Recurrent Head and Neck Carcinoma, Head and Neck Cancer Metastatic, Head or Neck Cancer
        
            
        
    
                
                                    Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008)
                                
            
            
        Active Not Recruiting
                            
            
                This study will evaluate the combination of a fixed dose pembrolizumab/vibostolimab co-formulation (MK-7684A) with etoposide/platinum chemotherapy followed by MK-7684A compared to the combination of atezolizumab with etoposide/platinum chemotherapy followed by atezolizumab in the first-line treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC). The primary hypothesis is, with respect to overall survival, MK-7684A in combination with the background therapy of etoposide/platinum followed b...  Read More             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                07/04/2025
            
            Locations: Infirmary Cancer Care ( Site 0022), Mobile, Alabama  +139 locations         
        
        
            Conditions: Small Cell Lung Carcinoma
        
            
        
    
                
                                    A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer
                                
            
            
        Recruiting
                            
            
                The purpose of this study is to find out if lower doses of radiation may help reduce the side effects of radiation therapy in combination with standard-of-care chemotherapy in people with HPV-positive throat cancer. The chemotherapy drugs used in this study include cisplatin, carboplatin, and 5-fluorouracil (5- FU), paclitaxel and abraxane- (Albumin-bound Paclitaxel).             
        
        
    Gender:
                ALL
            Ages:
                18 years and above
            Trial Updated:
                07/03/2025
            
            Locations: Memorial Sloan Kettering Cancer Center at Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey  +6 locations         
        
        
            Conditions: HPV, Throat Cancer, Oropharyngeal Carcinoma, Oropharyngeal Cancer, Human Papilloma Virus
        
            
        
    
                
                                    A Study of Osimertinib With or Without Chemotherapy as 1st Line Treatment in Patients With Mutated Epidermal Growth Factor Receptor Non-Small Cell Lung Cancer (FLAURA2)
                                
            
            
        Active Not Recruiting
                            
            
                The reason for the study is to find out if an experimental combination of an oral medication called osimertinib (TAGRISSO®) when used in combination with chemotherapy is more effective than giving osimertinib alone for the treatment of locally advanced or metastatic non-small cell lung cancer. Some lung cancers are due to mutations in the Deoxyribonucleic acid (DNA) which, if known, can help physicians decide the best treatment for their patients. One type of mutation can occur in the gene that...  Read More             
        
        
    Gender:
                ALL
            Ages:
                Between 18 years and 110 years
            Trial Updated:
                07/03/2025
            
            Locations: Research Site, Bellflower, California  +152 locations         
        
        
            Conditions: Non-Small Cell Lung Cancer
        
            
        
    193 - 204 of 1441
            